Clinical Trials Sponsored by Health Effects Institute

Total 24883 results

National Heart, Lung, and Blood Institute (NHLBI)

Completed

Methods to Enhance the Safety and Effectiveness of Stem Cell Transplants

Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Myelodysplastic Syndrome | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effects of Niacin Therapy on Lipoprotein Composition and Function

Cardiovascular Disease

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Bioprosthetic or Native Aortic Scallop Intentional Laceration to Prevent Iatrogenic Coronary Artery Obstruction (BASILICA) Prospective Investigation (BASILICA)

Native and Valve in Valve Aortic Valve Failure

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Combination Therapy of Severe Aplastic Anemia

Severe Aplastic Anemia

United States
National Institutes of Health Clinical Center (CC)
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Evaluation of Budesonide and How It Interacts With Antifungal Drugs in People With Gastrointestinal Graft-Versus-Host Disease

Stem Cell Transplantation | Graft vs Host Disease

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Collection of Biological Samples From Patients With Hepatitis-Associated Aplastic Anemia

Hepatitis-Associated Aplastic Anemia

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effect of Fasting on the Asthma Inflammasome

Asthma

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effect of Fasting on the NLRP3 Inflammasome

Cardiovascular Disease | Inflammatory Disease

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

An Evaluation of Safety and Efficacy of Escalating Doses of AMD3100 to Mobilize CD34+ Cells in Healthy Volunteers

Healthy Volunteers

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Mutations in Genes Associated With Pentalogy of Cantrell

Pentalogy of Cantrell

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Evaluation and Treatment of Patients With Lung Disease Not Participating in Research

Pulmonary Disease

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Niacin to Improve Blood Flow in People With Sickle Cell Disease

Sickle Cell Disease

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Collection of Blood From Patients With Pancytopenia

Pancytopenia

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Peripheral Stem Cell Transplant in Treating Patients With Metastatic Kidney Cancer

Kidney Cancer

United States
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Sildenafil to Treat HIV-Associated Pulmonary Hypertension

HIV

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Safety of ON 01910.Na in Patients With Myelodysplasia

Myelodysplastic Syndrome (MDS)

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Hydroxyurea for the Treatment of Patients With Sickle Cell Anemia

Sickle Cell Anemia

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Bone Marrow Stromal Cell Infusions for Stem Cell Transplant Complications

Graft-Versus-Host Disease

United States
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Biomarkers in Exhaled Breath From Asthmatic Patients

Asthma

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Collection of Blood, Bone Marrow, and Buccal Mucosa Samples From Healthy Volunteers for Center for Human Immunology, Autoimmunity, and Inflammatory Diseases (CHI) Laboratory Research Studies

Healthy Volunteers

United States
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Ultrasound and Other Images of Artery Blockages

Atherosclerosis

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

A Pilot Study of the Safety and Activity of Escalating Doses of ON 01910.Na in Patients With Relapsed Mantle Cell Lymphoma, Multiple Myeloma, Chronic Lymphocytic Leukemia, and Related Lymphoid Malignancies

Multiple Myeloma | Waldenstrom Macroglobulinemia | Leukemia, Lymphocytic, Chronic, B-Cell | Leukemia, Hairy Cell | Lymphoma, Mantle-cell

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Pulmonary Hypertension in Patients With Sickle Cell Disease in Nigeria

Sickle Cell Disease | Pulmonary Hypertension | Secondary Pulmonary Arterial Hypertension

Nigeria
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Therapeutic Application of Intravascular Nitrite for Sickle Cell Disease

Sickle Cell Anemia

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Cardiopulmonary Function Assessment and NO-Based Therapies for Patients With Hemolysis-Associated Pulmonary Hypertension

Pulmonary Hypertension

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Transcaval Access for Transcatheter Aortic Valve Replacement in People With No Good Options for Aortic Access

Aortic Valve Stenosis

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

A Pilot Study of Alemtuzumab (Campath[R]) in Patients With Myelodysplastic Syndrome

Myelodysplastic Syndromes

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Experimental Bone Marrow Transplant Protocol

Myelodysplastic Syndromes | Myeloproliferative Disorders | Chronic Myeloid Leukemia | Acute Lymphocytic Leukemia | Acute Myelocytic Leukemia

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Rituximab to Treat Moderate Aplastic Anemia, Pure Red Cell Aplasia, or Diamond Blackfan Anemia

Anemia, Aplastic | Red-Cell Aplasia, Pure | Anemia, Diamond-Blackfan

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effects of Roflumilast on Insulin and Blood Sugar Levels in Prediabetic Overweight and Obese Individuals

Obesity

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effects of Systemically Administered Hydrocortisone on the Immune System in Healthy Volunteers

Healthy | Healthy Subjects | Immunosuppression

United States
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Mutations Associated With Parkinson s Disease

Parkinson's Disease

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Danazol for Genetic Bone Marrow and Lung Disorders

Aplastic Anemia

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Stem Cell Transplantation for Patients With Cancers of the Blood

Acute Lymphocytic Leukemia | MDS (Myelodysplastic Syndrome) | CLL (Chronic Lymphocytic Leukemia) | CML (Chronic Myelogenous Leukemia) | AML (Acute Myelogenous Leukemia)

United States
National Heart, Lung, and Blood Institute (NHLBI)

Withdrawn

Imatinib and Carvedilol for High Blood Pressure in the Lungs in Adults With Sickle Cell Disease

Pulmonary Hypertension
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Ultra-Low Dose IL-2 Therapy as GVHD Prophylaxis in Haploidentical Allogeneic Stem Cell Transplantation

MDS | Chronic Lymphocytic Leukemia (CLL) | Acute Lymphoblastic Leukemia (ALL) | Acute Myelogenous Leukemia (AML) | Chronic Myelogenous Leukemia (CML)

United States
Emory University
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health...

Completed

Bone Marrow Transplantation in Young Adults With Severe Sickle Cell Disease (STRIDE)

Sickle Cell Disease

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Screening Protocol for Subjects Being Evaluated for Center for Human Immunology, Autoimmunity, and Inflammatory Diseases (CHI) Protocols

Healthy Volunteers | Autoimmune Disease | Inflammatory Disease | Immunologic Disease

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Gene Therapy for the Treatment of Fanconi's Anemia Type C

Pancytopenia | Fanconi's Anemia

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

X-ray Fluoroscopy Fused With Computed Tomography (XFC) Technical Development

Aortic Valve Stenosis

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Genes Causing Ebstein's Anomaly

Heart Defects, Congenital | Double Outlet Right Ventricle | Heart Septal Defects, Ventricle | Truncus Arteriosus, Persistent

United States, Belarus, Ukraine
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Catheter-Based Treatment of Cardiovascular Disease

Structural Heart Disease | Obstructive Coronary Artery Disease | Obstructive Peripheral Artery Disease

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Pilot Study to Assess the Proteome in Human Atrial Tissue

Diabetes | Cardiomyopathy

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

The Framingham Study: Examining DNA Markers and Links to Diseases

Vascular Diseases

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Dietary Nitrate and Nitrite to Increase Nitric Oxide in Patients With Coronary Artery Disease

Coronary Arteriosclerosis

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Pilot Study of Strength Testing in Overweight Women With or Without Insulin Resistance

Obesity

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Predicting Response to Cardiac Resynchronization Therapy in Heart Failure

Heart Failure | Left Ventricular Dysfunction

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Relation of White Blood Cell Function to Diabetes

Diabetes

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Collection of Heart Tissue Sample During Open Heart Surgery

Ischemia

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Treatment of Autoimmune Thrombocytopenia (AITP)

Thrombocytopenia | Autoimmune Disease | Autoimmune Hemolytic Anemia

United States

Clinical Trials Sponsored by Health Effects Institute

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