Clinical Trials Sponsored by Optos, PLC.

Total 11368 results

Pharmacyclics LLC.

Completed

Study of the Tolerability, Safety, and Pharmacokinetics of CRA-024781 in Cancer Patients

Neoplasms | Hematologic Neoplasms

United States
Lundbeck LLC

Completed

A Study of the Pharmacokinetics (PK) and Safety of IV Carbamazepine Relative to Oral Carbamazepine in Adults With Epilepsy

Epilepsy
MedImmune LLC

Withdrawn

A Study to Evaluate the Antitumor Activity and Safety of IPI-504 in Patients With Advanced Breast Cancer

Breast Cancer

United States
VIVUS LLC

Completed

A Study to Evaluate How VI-0521 Affect Cardiac Repolarization in Healthy Male and Female Volunteers (TQT)

Torsades de Pointes

United States
VIVUS LLC

Completed

A Drug Interaction Study of VI-0521 With Metformin, Sitagliptan and Probenecid in Healthy Subjects.

Obesity

United States
HairDx, LLC

Completed

Association of Polymorphisms in the Androgen Receptor Gene and Finasteride Response in Women With Androgenetic Alopecia

Androgenetic Alopecia
VIVUS LLC

Completed

To Evaluate The Effect Of Ketoconazole, Ritonavir and Erythromycin on the Safety and Pharmacokinetics of Avanafil

Erectile Dysfunction

United States
VIVUS LLC

Completed

A Study to Evaluate the Pharmacokinetics of VI-0521 Subjects With Renal Impairment

Renal Impairment

United States
MedImmune LLC

Completed

Respiratory Events Among Premature Infants

Respiratory Syncytial Virus

United States
MedImmune LLC

Completed

Study of MEDI-522 Administered by Subcutaneous Injection to Adults With Plaque Psoriasis

Psoriasis

United States, Canada
Pharmacyclics LLC.

Completed

A Study of Motexafin Gadolinium and Temozolomide for the Treatment of Malignant Gliomas

Glioma | Glioblastoma | Astrocytoma | Brain Neoplasm | Oligodendroglioma

United States
VIVUS LLC

Completed

Topical Alprostadil for Female Sexual Arousal Disorder

Sexual Dysfunction, Physiological

United States
MedImmune LLC

Completed

Phase I Trial of Weekly MEDI-522 in Patients With Refractory Solid Tumors

Cancer

France
MedImmune LLC

Completed

Study Evaluating the Addition of Amifostine (Ethyol®) to Idarubicin and Cytosine Arabinoside in Older Patients With Acute Myeloid Leukemia

Acute Myeloid Leukemia | Leukemia

United States, Israel
MedImmune LLC

Completed

Study of MEDI 507 in the Treatment of Pediatric Patients (Pediatric GvHD)

Graft Versus Host Disease

United States
MedImmune LLC

Completed

A Sequential Dose-Escalation Study in Subjects With Mild Asthma

Asthma

United States
MedImmune LLC

Completed

Study to Evaluate the Effectiveness of FluMist Vaccination in a School-Based Intervention Program

Influenza

United States
MedImmune LLC

Withdrawn

A Phase I Study to Evaluate Safety, Tolerability in Adults With Lymphoma

Lymphoma, B-Cell | Lymphoma, Non-Hodgkin
ParaPRO LLC

Completed

NatrOVA Photoallergy Study - NatrOVA Creme Rinse in Healthy Volunteers

Head Lice

United States
MedImmune LLC

Completed

Phase I Study of MEDI522 in Patients With Irinotecan-Refractory Advanced Colorectal Cancer

Cancer

United States
ParaPRO LLC

Completed

Phototoxicity Potential of NatrOVA Creme Rinse - 1%

Head Lice

United States
MedImmune LLC

Completed

MEDI-522 in the Treatment of Patients With Metastatic Androgen-Independent Prostate Cancer

Prostate Cancer

United States, Belgium, Israel, Russian Federation, Canada, Hungary, Poland
MedImmune LLC

Completed

A Phase II Study of MEDI-507, Administered by Injection to Adults With Psoriasis

Plaque Psoriasis

United States, Canada
MedImmune LLC

Completed

Study To Evaluate the Safety of Bivalent Vaccine

Healthy

United States
Pharmacyclics LLC.

Completed

Study of Motexafin Gadolinium and Docetaxel for Advanced Solid Tumors

Breast Neoplasms | Lung Neoplasms | Prostatic Neoplasms | Ovarian Neoplasms

United States
Pharmacyclics LLC.

Completed

Study of Neurologic Progression With Motexafin Gadolinium and Radiation Therapy (SMART)

Carcinoma, Non-Small-Cell Lung | Brain Neoplasms | Metastases, Neoplasm

United States, France, Belgium, Germany, Canada, Netherlands, Austria, Australia
Janssen Research & Development, LLC
Pharmacyclics LLC.

Recruiting

A Study to Customize Ibrutinib Treatment Regimens for Participants With Previously Untreated Chronic Lymphocytic Leukemia (TAILOR)

Leukemia, Lymphocytic, Chronic, B-Cell | Small Lymphocytic Lymphoma

United States, Italy, Poland, Spain, Czechia
Janssen Research & Development, LLC
Pharmacyclics LLC.

Active, not recruiting

A Study of Ibrutinib With Rituximab in Relapsed or Refractory Mantle Cell Lymphoma (VEGA)

Lymphoma, Mantle-Cell

Taiwan, Thailand, Malaysia, India, Puerto Rico, Spain, Turkey, Czechia, Brazil, Greece, Poland, Sweden, Romania
Janssen Research & Development, LLC
Pharmacyclics LLC.

Enrolling by invitation

A Long-term Extension Study of PCI-32765 (Ibrutinib) (CAN3001)

Follicular Lymphoma | Chronic Graft Versus Host Disease | Waldenstrom Macroglobulinemia | Mantle Cell Lymphoma | Chronic Lymphocytic Leukemia | Diffuse Large B-cell Lymphoma | Small Lymphocytic Lymphoma

United States, Spain, United Kingdom, Israel, Canada, Belgium, Poland, China, Japan, France, Korea, Republic of, Australia, Russian Federation, Turkey, Sweden, Italy, Mexico, Czechia, Ukraine, Brazil, Hungary, Portugal, Argentina, Col... and more
SGX Nova LLC

Completed

SCS Programming Study in Treating Intractable Chronic Back Pain (NOVA) (NOVA)

Chronic Back Pain

United States
Pharmacyclics LLC.
Janssen Research & Development, LLC

Active, not recruiting

Study of Ibrutinib Combined With Venetoclax in Subjects With Mantle Cell Lymphoma (SYMPATICO)

Mantle-Cell Lymphoma

France, Canada, Spain, United States, Hungary, Korea, Republic of, Greece, Australia, Netherlands, Belgium, United Kingdom, Czechia, Germany, Poland, Italy, Turkey, Ukraine
Cancer Insight, LLC
Elios Therapeutics, LLC

Completed

Phase IIB TL + YCWP + DC in Melanoma

Melanoma

United States
Lipac Oncology LLC
TesoRx Pharma, LLC

Completed

Proliposomal Intravesical Paclitaxel for Treatment of Low-Grade, Stage Ta, Non Muscle Invasive Bladder Cancer

Urologic Neoplasms | Urogenital Neoplasms | Urologic Diseases | Urinary Bladder Diseases | Urinary Bladder Neoplasms | Bladder Cancer | Transitional Cell Carcinoma of the Bladder | Non-Muscle Invasive Bladder Cancer | Urinary Bladder | Bladder Cancer Cell Transitional

United States
Grifols Therapeutics LLC
Grifols Biologicals, LLC

Terminated

Alphanate in Immune Tolerance Induction Therapy

Hemophilia A, Congenital

United States, Spain, Italy, India, Canada, Russian Federation
Grifols Therapeutics LLC
Grifols Biologicals, LLC

Completed

Efficacy and Safety of Plasma Exchange With Albutein® 5% in Participants With Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis

United States
Pharmacyclics LLC.
Janssen Research & Development, LLC

Completed

Study of the Bruton's Tyrosine Kinase Inhibitor in Subjects With Relapsed/Refractory Marginal Zone Lymphoma

B-cell Lymphoma | Marginal Zone Lymphoma

United States, Belgium, France, Germany, United Kingdom
MedRegen LLC

Not yet recruiting

MRG-001 in Patients With Amyotrophic Lateral Sclerosis

Motor Neuron Disease | Amyotrophic Lateral Sclerosis | Lou Gehrig Disease | Motor Neuron Atrophy
Adenocyte, LLC

Not yet recruiting

The LINFU® U.S. Registry in Patients With IPMN (Intraductal Papillary Mucinous Neoplasm of the Pancreas)

Pancreas Cancer | Pancreatic Cyst | IPMN, Pancreatic
Pharmtechnology LLC

Recruiting

Bioequivalence Study of Perindopril Tablets in Healthy Volunteers Under Fasting Conditions

Bioequivalence

Russian Federation
Mabscale, LLC

Recruiting

Study, Evaluating Pharmacokinetics, Pharmacodynamics, Immunogenicity and Safety Profiles of Rituximab Compared to MabThera® in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis

Russian Federation
Endourage, LLC

Recruiting

Symptom Tracking in Long COVID Patients Using Formula C™ Sublingual Drops

Long COVID | Long Covid19 | Post-Acute COVID-19 | Long Haul COVID | Long-Haul COVID-19 | Post-Acute COVID-19 Syndrome

United States
PYC Therapeutics

Not yet recruiting

Natural History of Autosomal Dominant Optic Atrophy (ADOA), Caused by OPA1 Mutation

Optic Atrophies, Hereditary | Autosomal Dominant Optic Atrophy | Optic Atrophy, Autosomal Dominant | Kjer Optic Atrophy

Australia
Gentuity, LLC

Recruiting

Clinical Feasibility Evaluation of the Gentuity HF-OCT Imaging System With Vis-M Micro-Imaging Catheter

Anatomy

Argentina
NeuroGlove LLC

Recruiting

NeuroGlove Anxiety and Depression Study

Depression | Anxiety | Anxiety Depression | Depression, Anxiety

United States
Mabscale, LLC

Recruiting

Study Evaluation of the Efficacy, Safety and Immunogenicity of Adalimumab in Comparison With Humira®

Plaque Psoriasis

Russian Federation
Fitbit LLC

Recruiting

Menstrual Cycle Study

Menstruation | Ovulation

United States
Neobiosis, LLC

Not yet recruiting

Safety, Efficacy, and Dosing of VIX001 in Patients With Neurological Symptoms of Post Acute COVID-19 Syndrome (PACS).

Cognitive Impairment | Neurological Complication | Post-Acute COVID-19 Syndrome
LianBio LLC

Recruiting

Phase I Study of the BBP-398 in Patients With Advance Solid Tumors

Advanced Solid Tumor | Advanced or Metastatic Non-small Cell Lung Cancer

China
PYC Therapeutics

Recruiting

Natural History of PRPF31 Mutation-Associated Retinal Dystrophy

Retinitis Pigmentosa | Eye Diseases, Hereditary | Retinal Dystrophies | Retinal Dystrophy Rod | Retinal Dystrophy Rod Progressive

United States, Australia
Nocira, LLC

Recruiting

AVPI Migraine Study (NC06)

Migraine

United States

Clinical Trials Sponsored by Optos, PLC.

Sponsors and Collaborators

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CROs in Israel

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