Search clinical trials for: Serotonin Uptake Inhibitors -- adverse effects

Total 146970 results

Washington University School of Medicine

Withdrawn

Fluvoxamine to Augment Olfactory Recovery For Long COVID-19 Parosmia (FluCOP)

COVID-19 | Olfactory Disorder | Parosmia

United States
Instituto Brasileiro de Controle do Cancer

Completed

Efficacy of Olanzapine, Netupitant and Palonosetron in Controlling Nausea and Vomiting Associated With Highly Emetogenic Chemotherapy in Patients With Breast Cancer (OLNEPA)

Nausea Post Chemotherapy

Brazil
Otsuka Pharmaceutical Development & Commercialization...

Completed

A Phase 1, Drug Interaction Study Between AVP-786 and Paroxetine and Between AVP-786 and Duloxetine in Healthy Subjects

Drug-drug Interaction

Australia
Organon and Co

Completed

Efficacy and Safety of Asenapine Using an Active Control in Subjects With Schizophrenia or Schizoaffective Disorder (25520)(P05846) (ACTAMESA)

Schizophrenia | Schizoaffective Disorder
Kristian Kjær Petersen
Aalborg University Hospital; CCBR, Aalborg

Completed

A Mechanism Based Proof of Concept Study of the Effects of Duloxetine in the Treatment of Patients With Osteoarthritic Knee Pain

Osteoarthritis, Knee

Denmark
Organon and Co

Completed

Long-Term Efficacy and Safety of Asenapine Using Olanzapine as a Positive Control (41512)(COMPLETED)(P05784)

Schizophrenia
Organon and Co

Completed

Efficacy and Safety of Asenapine With Placebo and Olanzapine (41021)(P05933)

Schizophrenia
Organon and Co

Completed

Efficacy and Safety of Asenapine Using an Active Control in Subjects With Schizophrenia or Schizoaffective Disorder (25517)(P05935)

Schizophrenia | Schizoaffective Disorder
Organon and Co

Completed

Efficacy and Safety of Asenapine Compared With Olanzapine in Patients With Persistent Negative Symptoms of Schizophrenia (25543)(COMPLETED)(P05817)

Schizophrenia
Organon and Co

Completed

Efficacy and Safety of Asenapine With Placebo and Olanzapine (41022)(P05947)

Schizophrenia
H. Lundbeck A/S

Completed

Comparison of Vortioxetine and Desvenlafaxine in Adult Patients Suffering From Depression (VIVRE)

Major Depressive Disorder

Spain, Czechia, Slovakia, Estonia, Sweden, Argentina, Belgium, Bulgaria, Latvia, Mexico, Russian Federation, Ukraine
Organon and Co

Completed

6-Month Extension Trial of Asenapine With Olanzapine in Negative Symptom Patients Who Completed the Protocol 25543 (25544)(P05777)

Schizophrenia
Organon and Co
Pfizer

Completed

40 Week Extension Study Of Asenapine and Olanzapine For Bipolar Disorder (A7501007)(COMPLETED)(P05857)

Bipolar Disorder
Organon and Co

Completed

6-Month Extension Trial of Asenapine With Olanzapine in Negative Symptoms Patients Who Completed the First 6- Month Trial (A7501014)(COMPLETED)(P05772)

Schizophrenia
Organon and Co

Completed

Efficacy and Safety of Asenapine Compared With Olanzapine in Patients With Persistent Negative Symptoms of Schizophrenia (A7501013)(COMPLETED)(P05771)

Schizophrenia
Organon and Co
Pfizer

Completed

9 Week Extension Study of Asenapine and Olanzapine in Treatment of Mania (P07007)(COMPLETED)

Bipolar Disorder
Organon and Co
Pfizer

Completed

3-Week Study of Asenapine, Olanzapine and Placebo for Treatment of Bipolar Mania (P07008)

Bipolar Disorder
Organon and Co

Completed

An Observational Drug Utilization Study of Asenapine in the United Kingdom (P08308)

Bipolar Disorder
Organon and Co
Pfizer

Completed

3-week Study of Asenapine, Olanzapine and Placebo for Treatment of Bipolar Mania (P07009)

Bipolar Disorder
Tel Aviv University
Tel-Aviv Sourasky Medical Center; Sheba Medical Center

Completed

Effect of Attention Training or SSRIs on Symptoms and Neural Activation in Social Anxiety

Social Anxiety Disorder

Israel
Rajavithi Hospital

Completed

Olanzapine for Chemotherapy-induced Nausea and Vomiting Prophylaxis (OLN-EME)

Complete Response Rate to Chemotherapy-induced Nausea and Vomiting Prophylaxis

Thailand
GlaxoSmithKline

Completed

Bioequivalence Study of Paroxetine and PAXIL Under Fasting Conditions in Healthy Mexican Participants

Anxiety Disorders

Mexico
Brain and Cognition Discovery Foundation

Completed

THINC-it Vortioxetine - Sensitivity to Change

Cognitive Change | Major Depressive Disorder

Canada
University Hospital, Basel, Switzerland

Completed

Effect of Methylenedioxymethamphetamine (MDMA) (Serotonin Release) on Fear Extinction (MFE)

Healthy

Switzerland
Instituto do Cancer do Estado de São Paulo

Completed

Pre-operative Olanzapine as Prophylactic Antiemetic in Oncologic Patients

Postoperative Nausea and Vomiting | Postoperative Nausea

Brazil
HealthPartners Institute

Completed

Olanzapine for Acute Headaches (Olanzapine)

Headache

United States
Istanbul Medipol University Hospital

Active, not recruiting

EEG Results of Deep TMS in Patients With OCD

Obsessive-Compulsive Disorder | EEG With Periodic Abnormalities

Turkey
Georgetown University
Patient-Centered Outcomes Research Institute

Completed

Treatments for Anxiety: Meditation and Escitalopram (TAME)

Anxiety Disorders | Generalized Anxiety Disorder | Social Anxiety Disorder | Panic Disorder | Agoraphobia

United States
Abivax S.A.

Completed

Evaluation of the Potential CYP1A2-mediated Drug Drug Interaction Safety, and Tolerability of ABX464

Healthy

United Kingdom
Jules Desmeules

Completed

Endobiotics for Phenotyping of Human Cytochrome P450 Enzymes (ENDOCYP2D6)

Healthy

Switzerland
Otsuka Pharmaceutical Development & Commercialization...

Terminated

To Assess the Safety and Tolerability of an Oral Aripiprazole/Escitalopram Combination Therapy in Participants With Major Depressive Disorder (MDD)

Major Depressive Disorder (MDD)
Otsuka Pharmaceutical Development & Commercialization...

Terminated

Study to Evaluate the Efficacy, Safety and Tolerability of an Oral Aripiprazole/Escitalopram Combination Therapy in Participants With Major Depressive Disorder (MDD)

Major Depressive Disorder (MDD)

United States, Spain, Hungary, South Africa, Croatia, France, Poland, India, Canada, Sweden, Malaysia
Roswell Park Cancer Institute

Completed

Gabapentin, Methadone, and Oxycodone With or Without Venlafaxine Hydrochloride in Managing Pain in Participants With Stage II-IV Squamous Cell Head and Neck Cancer Undergoing Chemoradiation Therapy

Stage III Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8 | Stage IV Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8

United States
Otsuka Pharmaceutical Development & Commercialization...
H. Lundbeck A/S

Completed

A Study of Flexible Dose Brexpiprazole as Monotherapy or Combination Therapy in the Treatment of Adults With Post-traumatic Stress Disorder (PTSD)

Stress Disorders, Post-Traumatic

United States
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Completed

Study of Desvenlafaxine in Treating Major Depressive Disorder.

Major Depressive Disorder

China
Janssen Scientific Affairs, LLC

Completed

A Study to Compare Disease Progression and Modification Following Treatment With Paliperidone Palmitate Long-Acting Injection or Oral Antipsychotics in Participant's With Recent-onset Schizophrenia or Schizophreniform (DREaM)

Psychotic Disorders | Schizophrenia

United States, Brazil, Mexico
Hospital Clinic of Barcelona

Completed

Risk Factors for AD-Associated Switch to Mania

Bipolar Disorder

Spain
Aziende Chimiche Riunite Angelini Francesco S.p.A
Cross Research S.A.

Completed

Bioavailability Study of 300 mg Trazodone Hydrochloride (New Polymer) vs. 300 mg Trazodone Hydrochloride (Contramid® Prolonged-release Tablets) Under Fasting Conditions

Healthy

Switzerland
Boehringer Ingelheim

Completed

A Study in People With Depression to Test the Effects of BI 1358894 on Parts of the Brain That Are Involved in Emotions

Depressive Disorder, Major

Germany
Bristol-Myers Squibb

Completed

Study to Characterize the Effects of Cytochrome p450 1A2 Inhibition on Systemic Exposure to BMS-986165

Healthy

United States
Joint Stock Company "Farmak"

Completed

Fasted Bioequivalence Study of 2 Olanzapine Film-coated Tablets, 5 mg, in Healthy, Adult Male and Female Subjects.

Pharmacokinetics

Czechia
University of North Carolina, Chapel Hill
National Institute of Mental Health (NIMH)

Completed

A Pilot Trial of Perinatal Depression Treatment in HIV Infected Women

HIV-1-infection | Perinatal Depression

Zambia
National Institute of Allergy and Infectious Diseases...

Terminated

Combination Pain Therapy in HIV Neuropathy

HIV Infections | Peripheral Neuropathy

United States
Otsuka Pharmaceutical Development & Commercialization...

Terminated

Study to Evaluate the Efficacy, Safety and Tolerability of an Oral Aripiprazole/Escitalopram Combination Therapy in Participants With Major Depressive Disorder (MDD)

Major Depressive Disorder (MDD)

United States, Australia, Bulgaria, Romania, India, Slovakia, Philippines
Otsuka Pharmaceutical Development & Commercialization...

Terminated

Study to Evaluate the Efficacy, Safety and Tolerability of an Oral Aripiprazole/Escitalopram Combination Therapy in Participants With Major Depressive Disorder (MDD)

Major Depressive Disorder (MDD)

Finland, Germany, Korea, Republic of, United States, Taiwan, Estonia, India, Italy, Mexico
National Cheng-Kung University Hospital

Terminated

The Therapeutic Effect of Transcranial Direct Current Stimulation on Depression in Parkinson's Disease (Parkinson's)

Depression | Parkinson Disease
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Sertraline Pediatric Registry for the Evaluation of Safety (SPRITES) (SPRITES)

Obsessive Compulsive Disorder

United States
Assiut University

Completed

Duloxetine Role in Reducing Opioid Consumption After Thoracotomy

Post-thoracotomy Pain

Egypt
Guangzhou General Hospital of Guangzhou Military...

Completed

The Effect of Venlafaxine on Language Function in Patients With Subcortical Aphasia: A fMRI Study

Ischemic Stroke | Subcortical Aphasia

China
Bogachan Sahin

Terminated

Fluoxetine for Visual Recovery After Ischemic Stroke (FLUORESCE)

Acute Stroke | Visual Field Loss

United States

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