Clinical Trials Sponsored by NHS England (NHSE/I) London

Total 1028 results

Moorfields Eye Hospital NHS Foundation Trust
King's College London; Cardiff University; University College, London; Newcastle... and other collaborators

Recruiting

Quality-Assured Follow-up of Quiescent Neovascular Age -Related maculaR dEgeneration by Non-medical Practitioners (FENETRE)

AMD

United Kingdom
Institute of Cancer Research, United Kingdom
Royal Marsden NHS Foundation Trust; Nottingham University Hospitals NHS Trust; Barts & The London NHS Trust and other collaborators

Recruiting

The BARCODE 2 Study - The Use of Genetic Profiling to Guide Prostate Cancer Treatment (BARCODE2)

Hormone Refractory Prostate Cancer

United Kingdom
NHS National Waiting Times Centre Board
NHS Greater Glasgow and Clyde; University of Glasgow; Royal London Hospital

Not yet recruiting

Incidence, Impact and Mechanisms of Perioperative Right VEntricular Dysfunction (IMPRoVE) (IMPRoVE)

Right Ventricular Dysfunction

United Kingdom
Chelsea and Westminster NHS Foundation Trust
Imperial College London; Imperial College Healthcare NHS Trust; University of...

Completed

PRIME: Cognitive Outcome Following Major Burns (PRIME)

Depression | Quality of Life | Burns | Cognitive Dysfunction | Anxiety | PostTraumatic Stress Disorder | Inflammation, Brain

United Kingdom
Innersight Labs Ltd
King's College London; Guy's and St Thomas' NHS Foundation Trust; Sheffield Teaching... and other collaborators

Not yet recruiting

Virtual 3D Modelling for Improved Surgical Planning of Robotic-assisted Partial Nephrectomy (VISP)

Kidney Cancer
Queen Mary University of London
Biogen; Barts & The London NHS Trust; Moorfields Eye Hospital NHS Foundation... and other collaborators

Recruiting

Natalizumab for the Treatment of People With Inflammatory Demyelination Suggestive of Multiple Sclerosis, or Definite Multiple Sclerosis, at First Presentation (AttackMS) (AttackMS)

Multiple Sclerosis | Clinically Isolated Syndrome of Demyelination

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...
Imperial College London; Barts & The London NHS Trust; Intensive Care National...

Completed

FIRST-line Support for Assistance in Breathing in Children (FIRST-ABC) Feasibility Study (FIRST-ABC)

Hypoxia | Respiratory Acidosis | Moderate/Severe Respiratory Distress

United Kingdom
University College, London
Norfolk and Norwich University Hospitals NHS Foundation Trust; The Christie... and other collaborators

Recruiting

VideoEndoscopic Radical Inguinal Lymphadenectomy for Penile Cancer (VELRAD)

Melanoma | Penile Cancer | Inguinal Lymphadenopathy

United Kingdom
Imperial College London
Nottingham University Hospitals NHS Trust; Royal Brompton & Harefield NHS Foundation... and other collaborators

Not yet recruiting

Nebulised Hypertonic Saline to Decrease Respiratory Exacerbations in Neuromuscular Disease or Neurodisability (SPICE-UP)

Cerebral Palsy | Neuromuscular Diseases | Neurodevelopmental Disorders

United Kingdom
King's College Hospital NHS Trust
King's College London; Cardiff University; Brighton and Sussex University Hospitals...

Recruiting

Beta-blockers or Placebo for Primary Prophylaxis (BOPPP) of Oesophageal Varices Trial. (BOPPP)

Portal Hypertension | Cirrhosis, Liver | Variceal Hemorrhage | Varices, Esophageal

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
University College London Hospitals; Guy's and St Thomas' NHS Foundation Trust

Recruiting

Connecting Breath and Mind for CYP With Long COVID

Anxiety | Post-COVID-19 Syndrome | Breathlessness

United Kingdom
King's College London
Guy's and St Thomas' NHS Foundation Trust; Brighton and Sussex University Hospitals...

Recruiting

A Study to Measure the Expression of the HER2-HER3 Dimer in Tumour and Blood (Exosomes) Samples From Patients With HER2 Positive Breast Cancer Receiving HER2 Targeted Therapies (HERdi PREDICT)

HER2-positive Breast Cancer

United Kingdom
St George's, University of London
King's College Hospital NHS Trust; Guy's and St Thomas' NHS Foundation Trust

Completed

Exercise Training in Hypertrophic Cardiomyopathy: (SAFE-HCM) (SAFE-HCM)

Hypertrophic Cardiomyopathy

United Kingdom
Heart of England NHS Trust
University of Birmingham; National Institute for Health Research, United Kingdom

Completed

A Study of Home Monitoring in Adults With Cystic Fibrosis (HOMECF) (HOME-CF)

Cystic Fibrosis

United Kingdom
University College, London
King's College London; King's College Hospital NHS Trust; University of Oxford; Great Ormond Street Hospital for Children NHS Foundation Trust

Recruiting

Children's Adaptive Deep Brain Stimulation for Epilepsy Trial (CADET): Pilot (CADET Pilot)

Epilepsy | Lennox-Gastaut Syndrome, Intractable

United Kingdom
Imperial College London
The Leeds Teaching Hospitals NHS Trust; Norfolk and Norwich University Hospitals... and other collaborators

Completed

Idiopathic Pulmonary Fibrosis Job Exposures Study (IPFJES)

Idiopathic Pulmonary Fibrosis | IPF

United Kingdom
University College, London
Yale University; Barts & The London NHS Trust; Queen Mary University of London; University of Bristol

Completed

Variation Between Hospitals in Short-term Mortality After Acute Coronary Syndromes: A CALIBER Study

Acute Coronary Syndrome

United Kingdom
Edinburgh Napier University
King's College London; University of Edinburgh; NHS Lothian; University of Manchester and other collaborators

Recruiting

DEcision-making Capacity: Intervention Development & Evaluation in Schizophrenia-spectrum Disorder (DEC:IDES)

Schizophrenia and Related Disorders | Mental Competency

United Kingdom
King's College London
Royal Free Hospital NHS Foundation Trust; Chelsea and Westminster NHS Foundation... and other collaborators

Recruiting

Muscle Connective Tissue in Limb Development and Disease

Radial Dysplasia

United Kingdom
Imperial College London
Royal Marsden NHS Foundation Trust; Newcastle University; University of Manchester and other collaborators

Completed

Evaluation of [18F]Fluoroethyl Triazole Labelled [Tyr3]-Octreotate Analogues for the Imaging of Neuroendocrine Tumours. (FETONET)

Neuroendocrine Tumors
University of Manchester
King's College Hospital NHS Trust; Cardiff University; University College London... and other collaborators

Not yet recruiting

Immune Profiles in Myasthenia Gravis

Myasthenia Gravis
Sheffield Teaching Hospitals NHS Foundation Trust
Manchester Metropolitan University; University of Sheffield; Health Education...

Recruiting

The Effect of Lycopene on Sperm Quality in Men Attending Fertility Clinic

Total Motile Sperm Count

United Kingdom
Imperial College London
Royal Free Hospital NHS Foundation Trust; Mid and South Essex NHS Foundation... and other collaborators

Recruiting

Finding the Invasive Haemodynamic Threshold for Symptom Relief in Stable Angina (ORBITA-FIRE)

Stable Angina

United Kingdom
King's College London
Imperial College London; University of Oxford; Sheffield Teaching Hospitals NHS...

Unknown

Pain In Neuropathy Study (PINS)

Chronic Pain | Carpal Tunnel Syndrome | Neuropathic Pain | Diabetic Neuropathy | Peripheral Neuropathies

United Kingdom
University of Bath
South London and Maudsley NHS Foundation Trust; Avon and Wiltshire Mental Health...

Unknown

Examining the Feasibility and Acceptability of Good Quality Intensive CBT for OCD and Good Quality Weekly CBT for OCD

Obsessive Compulsive Disorder (OCD)

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
King's College London; King's College Hospital NHS Trust; Somerset NHS Foundation... and other collaborators

Not yet recruiting

PROSAIC-DS Study (PROState AI in Cancer - Decision Support) (PROSAIC-DS)

Prostate Cancer

United Kingdom
University Hospital Southampton NHS Foundation...
Imperial College London; University of Bristol; University Hospitals Bristol... and other collaborators

Completed

Evaluation of Corticosteroid Therapy in Childhood Severe Sepsis - a Randomised Pilot Study (StePS)

Sepsis

United Kingdom
Royal Marsden NHS Foundation Trust
University College, London; The Leeds Teaching Hospitals NHS Trust; Belfast Health... and other collaborators

Unknown

Targeted Radiotherapy in Androgen-suppressed Prostate Cancer Patients. (TRAP)

Prostate Cancer | Metastasis | Toxicity Due to Radiotherapy | Circulating Tumour DNA

United Kingdom
University College, London
Barts & The London NHS Trust; Anticancer Fund, Belgium; JP Moulton Charitable...

Recruiting

Adaptive ChemoTherapy for Ovarian Cancer in Patients With Replased Platinum-sensitive High Grade Serous or High Grade Endometrioid Ovarian Cancer (ACTOv)

Ovarian Cancer | Fallopian Tube Cancer | Relapsed Ovarian Cancer | Peritoneal Cancer | High Grade Serous Carcinoma | Ovary Cancer | Endometrioid Carcinoma

United Kingdom
Imperial College London
University College London Hospitals; Northern Care Alliance NHS Foundation... and other collaborators

Recruiting

Augmented Response of Volatile Biomarkers in Assessment of Oesophagogastric Cancer (AROMA 1 / BIORESOURCE)

Gastric Cancer | Oesophageal Cancer | Microbiome | Volatile Organic Compounds | Transcriptomics | Microbioata | Breath Analysis | Volatalomics | Metabonomics/Lipidomics | Microbiome Analysis

United Kingdom
Imperial College London
Royal Marsden NHS Foundation Trust; University College London Hospitals; The... and other collaborators

Completed

Cancer Loyalty Card Study (CLOCS)

Ovarian Neoplasms

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
Imperial College London; Edwards Lifesciences

Not yet recruiting

Computational Assessment of Bioprosthetic Aortic Valve Function

Valve Heart Disease | CFD
Lunit Inc.
King's College London; The Leeds Teaching Hospitals NHS Trust

Not yet recruiting

Real World Evaluation of Lunit INSIGHT MMG Technology

Breast Cancer | Breast Diseases

United Kingdom
King's College Hospital NHS Trust
King's College London; Danish Epilepsy Centre

Recruiting

Mos-FED (Mosaicism in Focal Epilepsy Cortical Dysplasia Tissue) (MosFED)

Epilepsy | Focal Cortical Dysplasia

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
City, University of London

Not yet recruiting

Comparison of Two Aspheric Intraocular Lenses for Micro-monovision

Cataract | Presbyopia | Pseudophakia

United Kingdom
Chelsea and Westminster NHS Foundation Trust
Imperial College London; CW plus

Recruiting

The Effect of Music on Patients in Critical Care (EMPIRE)

Intensive Care

United Kingdom
Imperial College London
Novartis; Imperial College Healthcare NHS Trust; Rigel Pharmaceuticals

Recruiting

Inflammatory Signal Inhibitors for COVID-19 (MATIS) (MATIS)

Pneumonia | Covid19 | Coronavirus

United Kingdom
Chiesi UK
Imperial College London; The Leeds Teaching Hospitals NHS Trust

Active, not recruiting

The Effect of Surfactant Dose on Outcomes in Preterm Infants With RDS (OPTI-SURF)

Respiratory Distress Syndrome | Bronchopulmonary Dysplasia

United Kingdom
Chelsea and Westminster NHS Foundation Trust
Gilead Sciences; Imperial College London

Terminated

Efficacy, Tolerability and Acceptability of Biktarvy by TPLWH

Human Immunodeficiency Virus

United Kingdom
Chelsea and Westminster NHS Foundation Trust
Gilead Sciences; Imperial College London

Completed

Efficacy of BIC/F/TAF Versus Standard of Care in the Treatment of New HIV Infection Diagnoses in the Context of 'Test and Treat' (BIC-T&T)

Human Immunodeficiency Virus

United Kingdom
King's College London
Bayer; Guy's and St Thomas' NHS Foundation Trust

Completed

MR INFORM - MR Perfusion Imaging to Guide Management of Patients With Stable Coronary Artery Disease

Coronary Artery Disease | Stable Angina | Myocardial Ischaemia

United Kingdom
Brighton and Sussex University Hospitals NHS Trust
St Thomas' Hospital, London

Withdrawn

RCT: Compare - Pneupac VR1 to Manual Ventilation in Intubated Patients

Cancer
Imperial College London
Royal Brompton & Harefield NHS Foundation Trust; Asthma UK

Completed

Airway Smooth Muscle and Asthma Severity

Asthma

United Kingdom
Royal Marsden NHS Foundation Trust
University College London (UCL) Cancer Institute

Unknown

Exploratory Study of Molecular Characterization in Patients With Metastatic Germ Cell Tumours Refractory/Resistant to Platinum Treatment (EMIT)

Testicular Germ Cell Tumor

United Kingdom
GlaxoSmithKline
Imperial College London; Guy's and St Thomas' NHS Foundation Trust

Terminated

PET Study to Study Tumour Apoptosis

Cancer

United Kingdom
Imperial College London
Royal Brompton & Harefield NHS Foundation Trust; Hill-Rom

Completed

High Frequency Chest Wall Oscillation and Cystic Fibrosis

Cystic Fibrosis

United Kingdom
London South Bank University
Guy's and St Thomas' NHS Foundation Trust

Completed

Acupuncture for the Treatment of Phantom Limb Syndrome

Phantom Limb Syndrome

United Kingdom
St George's, University of London
University Hospital Southampton NHS Foundation Trust; St George's University...

Recruiting

Eosinophilic Oesophagitis Assessment With String Testing (EoEAST)

Eosinophilic Esophagitis

United Kingdom
Royal Marsden NHS Foundation Trust
University College London Hospitals; Great Ormond Street Hospital for Children...

Recruiting

Pelvic Radiation Disease in Childhood Cancer Survivors

Radiation Disease

United Kingdom
Barts & The London NHS Trust
Liverpool Heart and Chest Hospital NHS Foundation Trust; Aortic Dissection...

Recruiting

Living With Marfans and Your Aorta: Surgical Outcomes Study (LIMA II)

Marfan Syndrome | Marfan Syndrome Cardiovascular Manifestations

United Kingdom

Clinical Trials Sponsored by NHS England (NHSE/I) London

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