Clinical Trials Sponsored by Onconova Therapeutics, Inc

Total 2992 results

Pearl Therapeutics, Inc.

Completed

Phase I Study Evaluating the Safety and Pharmacokinetics of Budesonide, Glycopyrronium, and Formoterol Fumarate Inhalation Aerosol (BGF MDI) in Healthy Volunteers

Healthy Volunteers

United States
Melinta Therapeutics, Inc.

Completed

Safety and Efficacy Study of Oxazolidinones to Treat Uncomplicated Skin Infections

Streptococcal Infections | Abscess | Staphylococcal Skin Infections | Infectious Skin Diseases | Bacterial Skin Diseases

United States
Nivalis Therapeutics, Inc.

Completed

Safety and Tolerability Study of N6022 in Healthy Subjects

Healthy

United States
Avalo Therapeutics, Inc.

Completed

Antitussive Effects of FP01 Lozenges in Subjects With Cough Due to Upper Respiratory Tract Infection

Acute Cough

Chile, Peru
Revance Therapeutics, Inc.

Completed

A 4-Arm Efficacy and Safety Study of RT001 for the Treatment of Moderate to Severe Lateral Canthal Lines in Adults

Facial Wrinkles | Lateral Canthal Lines | Crow's Feet

United States
Repros Therapeutics Inc.

Completed

Comparison of Two Formulations of Proellex for Vaginal Administration

Comparison of 2 Different Formulations of 12 mg Proellex Vaginal Capsules

United States
Ortek Therapeutics, Inc.

Completed

Comparison of Early Caries Detection in Children Utilizing an Electrical Conductance Device and the Gold Standard of Visual-tactile Technique.

Dental Caries in Children

Venezuela
Tarsa Therapeutics, Inc.

Completed

A Study Comparing Oral Calcitonin to Nasal Spray Calcitonin in Postmenopausal Osteoporotic Women (ORACAL)

Osteoporosis, Postmenopausal

United States, United Kingdom, Bulgaria, Hungary, Poland, South Africa
Revance Therapeutics, Inc.

Completed

Safety and Efficacy Study of RT001 to Treat Moderate to Severe Lateral Canthal Lines

Facial Wrinkles | Lateral Canthal Lines | Crow's Feet

United States
Revance Therapeutics, Inc.

Completed

Safety and Efficacy Study of RT001 to Treat Moderate to Severe Lateral Canthal Lines

Facial Wrinkles | Lateral Canthal Lines | Crow's Feet

United States
INSYS Therapeutics Inc

Completed

Long-term Safety and Efficacy Study of Fentanyl Sublingual Spray for the Treatment of Breakthrough Cancer Pain

Pain | Cancer

United States, India, Canada
Mati Therapeutics Inc.

Completed

A Dose Evaluation Study of the Effect of Plug Placement on the Efficacy and Safety of the Latanoprost Punctal Plug Delivery System (L-PPDS) in Subjects With Ocular Hypertension or Open-Angle Glaucoma

Glaucoma | Ocular Hypertension (OH)

United States
Mati Therapeutics Inc.

Completed

Safety and Efficacy of Punctum Plug Delivery System in Subjects With Open-Angle Glaucoma or Ocular Hypertension (CORE)

Ocular Hypertension | Glaucoma

United States
Seaside Therapeutics, Inc.

Completed

Efficacy and Safety Study of STX209 (Arbaclofen) for the Treatment of Social Withdrawal in Children With Fragile X Syndrome (Harbor-C)

Fragile X Syndrome

United States
Tobira Therapeutics, Inc.

Completed

A Proof of Concept Study to Evaluate the Antiviral Activity, Safety, and Pharmacokinetics of the CCR5 Antagonist TBR 652 in HIV 1-Infected, Antiretroviral Treatment-Experienced, CCR5 Antagonist-Naïve Patients

HIV-1 Infection
Aileron Therapeutics, Inc.

Completed

Phase 1 Safety Study of ALRN-5281 in Healthy Subjects

Growth Hormone Deficiency

United States
Oraya Therapeutics, Inc.

Unknown

An Open-label Study to Evaluate the Clinical and Economic Benefits of I-Ray in Patients With Choroidal Neovascularization Secondary to Age-related Macular Degeneration (ENDEAVOUR)

Eye Diseases | Age-Related Macular Degeneration | Macular Degeneration | Retinal Diseases | Wet Macular Degeneration

United Kingdom
INSYS Therapeutics Inc

Completed

Pharmacokinetic Study of Fentanyl 400 µg Sublingual Spray, Actiq® 400 µg Transmucosally, and Fentanyl Citrate Injection 100 µg Intravenously (iv)

Pain

United States
Orexigen Therapeutics, Inc

Terminated

Olanzapine Given in Combination With Zonisamide SR to Prevent Weight Gain in Schizophrenic Subjects

Schizophrenia | Schizoaffective Disorder | Schizophreniform Disorder

United States
Orexigen Therapeutics, Inc

Terminated

Naltrexone SR and Fluoxetine Combination Therapy in Subjects With Obsessive-Compulsive Disorder

Obsessive-Compulsive Disorder

United States
Orexigen Therapeutics, Inc

Completed

A Study of Naltrexone SR/ Bupropion SR in Overweight or Obese Subjects With Major Depression

Depression

United States
Oraya Therapeutics, Inc.

Unknown

Iray for Vascularized Pigment Epithelial Detachment (VPED) Secondary to Age Related Macular Degeneration

Age Related Macular Degeneration | Retinal Pigment Epithelial Detachment With Vascularization

Italy
Azaya Therapeutics, Inc.

Completed

Safety Study of a Liposomal Docetaxel Formulation in Patients With Solid Tumors Who Have Failed Previous Therapies

Breast Cancer | Pancreatic Cancer | Ovarian Cancer | Solid Tumor | Non-Small Cell Lung

United States
INSYS Therapeutics Inc

Completed

Efficacy and Safety Study of LEP-ETU to Treat Metastatic Breast Cancer

Breast Cancer

India
Avalo Therapeutics, Inc.

Completed

A Single Dose Study to Determine the Safety and Pharmacokinetics of FP01 Lozenges in Healthy Volunteers

Healthy

United States
INSYS Therapeutics Inc

Completed

Comparative Bioavailability of Dronabinol Oral Solution Versus Branded Capsule 5 mg Under Fasting Conditions

Bioavailability

United States
Biolex Therapeutics, Inc.

Completed

Study of Safety, Tolerability, and Anti-Viral Effect of Locteron Compared to PEG-Intron in Patients With Chronic Hepatitis C (PLUS)

Hepatitis C

United States
Oraya Therapeutics, Inc.

Withdrawn

Study to Evaluate the Safety and Effectiveness of IRay in Wet Age-related Macular Degeneration (AMD) Patients With Recurrent Leakage Secondary to Choroidal Neovascularisation (CNV)

Macular Degeneration | Age-related Macular Degeneration | AMD | Wet AMD | Wet Age-related Macular Degeneration

United Kingdom, Italy
INSYS Therapeutics Inc

Completed

Pre-operative IL13-PE38QQR in Patients With Recurrent or Progressive Malignant Glioma

Glioblastoma Multiforme | Malignant Glioma | Anaplastic Astrocytoma | Mixed Oligoastrocytoma

United States, Germany, Israel
InVasc Therapeutics, Inc.

Completed

Study to Determine the Effects of Nebivolol and Hydrochlorothiazide in African Americans With Hypertension (NASAA)

Hypertension

United States
Altheus Therapeutics, Inc.

Completed

Study of the Safety and Tolerability of ALTH12 Versus Mesalamine Enema in Subjects With Left-Sided Ulcerative Colitis

Ulcerative Colitis

United States
Pearl Therapeutics, Inc.

Completed

Study to Evaluate the Safety and Efficacy of Inhaled PT005 in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease

Australia, New Zealand
Altair Therapeutics, Inc.

Completed

Study Evaluating the Effects of AIR645 on Allergen-Induced Airway Responses in Subjects With Mild Atopic Asthma

Asthma

Canada
OcuNexus Therapeutics, Inc.

Withdrawn

A Study to Investigate the Safety and Clinical Effect of Nexagon® to Treat Persistent Epithelial Defects

Persistent Epithelial Defect
Sarepta Therapeutics, Inc.

Terminated

Safety and Efficacy Study of AVI-5126 When Used on Vein Grafts Before Use in Heart by-Pass Graft Surgery (CABG)

Cardiovascular Disease | Coronary Artery Bypass

Ukraine
Sarepta Therapeutics, Inc.

Terminated

An Exploratory Study of AVI-4020 in Patients With Possible Acute Neuroinvasive West Nile Virus (WNV) Disease

West Nile Fever
Sarepta Therapeutics, Inc.

Completed

Pharmacokinetic Study in Cerebral Spinal Fluid After a Single Dose of AVI-4020

West Nile Virus

United States
Dharma Therapeutics Inc.

Completed

Safety and Efficacy Study of an Iontophoretic Patch Containing Lidocaine and Epinephrine for Venipuncture in Healthy Adult Volunteers

Local Anesthesia

United States
OcuNexus Therapeutics, Inc.

Completed

A Study Evaluating Nexagon™ in the Treatment of Skin Wounds.

Wound Healing

New Zealand
Y's Therapeutics, Inc.

Unknown

YSPSL for Prevention of Ischemic Reperfusion Injury in Patients Undergoing Cadaveric Orthotopic Liver Transplantation (YSPSL)

Ischemia Reperfusion Injury

United States
Synvista Therapeutics, Inc

Terminated

Efficacy and Safety of Topical ALT-2074 (SYI-2074) for Treatment of Chronic Plaque Psoriasis

Psoriasis

Israel
Synvista Therapeutics, Inc

Completed

Evaluation of ALT-2074 in Subjects With Type-2 Diabetes, Haptoglobin Type 2-2 Genotype and Coronary Artery Disease

Coronary Artery Disease | Diabetes

United States
Anza Therapeutics, Inc.

Completed

Study of Safety and Tolerability of Intravenous CRS-100 in Adults With Carcinoma and Liver Metastases

Carcinoma | Neoplasm Metastasis | Liver Neoplasms

United States
Orexigen Therapeutics, Inc

Completed

Safety and Efficacy of Different Combinations of Zonisamide-CR Plus Bupropion-SR to Treat Uncomplicated Obesity

Obesity

United States
Sarepta Therapeutics, Inc.

Terminated

A Phase 1b Study Evaluating RESTEN-MP in Subjects With Focal de Novo Stenosis

Coronary Artery Disease | Coronary Stent Restenosis
Y's Therapeutics, Inc.

Unknown

YSPSL for Prevention of Delayed Graft Function in Cadaveric Liver Transplantation

Liver Diseases

United States
Y's Therapeutics, Inc.

Completed

YSPSL for Prevention of Delayed Graft Function Part A

Delayed Graft Function

United States
Sirion Therapeutics, Inc.

Completed

Study of Cyclosporine in the Treatment of Dry Eye Syndrome (ST-603-006)

Dry Eye Syndromes

United States
Sirion Therapeutics, Inc.

Completed

Study of Difluprednate Ophthalmic Emulsion in the Treatment of Postoperative Inflammation

Inflammation
Sirion Therapeutics, Inc.

Completed

Study of Difluprednate Ophthalmic Emulsion in the Treatment of Severe Uveitis

Panuveitis | Uveitis

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