Search clinical trials for: Adult moderate to serve SLE

Total 479725 results

AbbVie

Active, not recruiting

A Study to Assess the Adverse Events and Effectiveness of BOTOX Injections for the Treatment of Moderate to Severe Forehead Lines in Chinese Adult Participants

Forehead Lines

China
Eli Lilly and Company

Active, not recruiting

A Study of Lebrikizumab (LY3650150) in Adult and Adolescent Participants With Moderate-to-Severe Atopic Dermatitis Previously Treated With Dupilumab (ADapt)

Atopic Dermatitis

United States
Vedic Lifesciences Pvt. Ltd.

Completed

A Study to Evaluate the Efficacy of UP165 on Sleep Quality and Mood State in Healthy Adults

Sleep Disturbance

India
AbbVie

Enrolling by invitation

A Study to Evaluate Upadacitinib in Combination With Topical Corticosteroids in Adolescent and Adult Participants With Moderate to Severe Atopic Dermatitis (AD Up)

Atopic Dermatitis

United States, Australia, Austria, Belgium, Canada, China, Czechia, France, Germany, Greece, Hong Kong, Hungary, Ireland, Israel, Italy, Japan, Netherlands, New Zealand, Norway, Puerto Rico, Slovakia, Spain, Sweden, United Kingdom
Penn State University
University of Arizona; Proactive Life Inc

Completed

Enhanced CBTi for Older Adult Sleep and Cognition (R44)

Insomnia | Alzheimers Disease Related Dementias

United States
University Hospital, Ghent
University Ghent

Completed

24-hour Movement Behaviors Among Normal Weight, Overweight and Obese Adults (OwOb_24hmb)

Overweight and Obesity

Belgium
GlaxoSmithKline

Completed

Study to Evaluate Immunogenicity and Safety of GSK Biologicals' Herpes Zoster Subunit (HZ/su) Vaccine at 9 and 10 Years After Vaccine Administration and Assessment of Re-vaccination With 2 Additional Doses at 10 Years After Initial Vaccination, in Healthy Subjects Aged 60 Years of Age(YOA) and Older

Herpes Zoster

Germany, Czechia, Sweden
Eli Lilly and Company
Shanghai Junshi Bioscience Co., Ltd.; AbCellera Biologics Inc.

Completed

A Study of LY3819253 (LY-CoV555) and LY3832479 (LY-CoV016) in Participants With Mild to Moderate COVID-19 Illness (BLAZE-1)

COVID-19

United States
Kodiak Sciences Inc

Terminated

A Study to Evaluate the Efficacy and Safety of Intravitreal KSI-301 in Participants With Moderately Severe to Severe Non-proliferative Diabetic Retinopathy (NPDR) (GLOW)

Non-proliferative Diabetic Retinopathy

United States, Latvia, Slovakia, Poland, Puerto Rico, Spain, Czechia
Parc de Salut Mar

Active, not recruiting

Asthma Research in Children and Adolescents (ARCA)

Asthma in Children | Persistent Asthma | Asthma Exacerbation

Spain
Invirsa, Inc.
Biomedical Advanced Research and Development Authority

Completed

Study of INV-102 Ophthalmic Solution in Adults With Moderate Symptomatic Dry Eye Disease

Dry Eye Disease

United States
Vifor Fresenius Medical Care Renal Pharma
Tigermed Consulting Co., Ltd

Active, not recruiting

Phase 3 Study of Difelikefalin in Haemodialysis Chinese Adult Subjects With Moderate-to-Severe Pruritus

Uremic Pruritus

China
MiNK Therapeutics

Completed

Evaluate the Safety of agenT-797 in Participants With Moderate to Severe Difficulty Breathing Secondary to SARS-CoV-2

Respiratory Distress Syndrome, Adult

United States
Concert Pharmaceuticals

Completed

A Study to Evaluate the Durability of Response Study of CTP-543 in Adult Patients With Moderate to Severe Alopecia Areata

Alopecia Areata

United States
University of Alberta
Alberta Health services; Glenrose Foundation

Active, not recruiting

Smart Home Technologies for Assessing and Monitoring Frailty in Older Adults

Healthy | Frail Elderly Syndrome | Frailty | Healthy Aging | Frailty Syndrome | Aging Problems | Aging Disorder | Pre-Frailty

Canada
Lallemand Health Solutions

Completed

Probiotics on Sleep Among Adults Study

Sleep Disturbance | Sleep Patterns

Canada
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Donor Peripheral Stem Cell Transplant in Treating Patients With Advanced Hematologic Cancer or Other Disorders

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Diseases | Graft Versus Host Disease | Precancerous/Nonmalignant Condition
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Vaccine Therapy in Preventing Cytomegalovirus Infection in Patients With Hematological Malignancies Undergoing Donor Stem Cell Transplant

Primary Myelofibrosis | Polycythemia Vera | Essential Thrombocythemia | Stage I Multiple Myeloma | Stage II Multiple Myeloma | Stage III Multiple Myeloma | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid... and other conditions

United States
Oticon Medical

Terminated

A Monocentric Study Evaluating Pupillometry as an Objective Measurement for CI Fittings (PupillOM)

Hearing Loss, Sensorineural | Hearing Loss, Bilateral | Cochlear Hearing Loss | Hearing Loss, Cochlear

France
TrialSpark

Completed

A Study to Evaluate the Anti-pruritic Effectiveness of ASN008 in Adults With Mild to Moderate Atopic Dermatitis

Dermatitis, Atopic | Pruritus

United States
M.D. Anderson Cancer Center

Completed

Exploring the Neuro-Immune Basis of Cancer-Related Fatigue Using Behavioral Measures

Head and Neck Cancer

United States
Millennium Pharmaceuticals, Inc.

Completed

A Study to Evaluate the Safety, Pharmacokinetics (PK), and Pharmacodynamics (PD) of TAK-079 in Combination With Standard Background Therapy in Participants With Moderate to Severe Systemic Lupus Erythematosus (SLE)

Systemic Lupus Erythematosus | Lupus Erythematosus, Systemic

United States
Boston University
Pfizer

Terminated

Improvement In Scratch Behavior And Sleep In Patients With Atopic Dermatitis (PAD)

Atopic Dermatitis

United States
University of Kansas Medical Center

Completed

Cooking Classes for Young Adults With ID (ChefBoyID)

Intellectual Disability, Mild to Moderate

United States
Shionogi

Completed

Evaluation of S-600918 in Adults With Refractory Chronic Cough

Chronic Cough

United States, United Kingdom, Japan, Ukraine, Poland, Czechia
Milton S. Hershey Medical Center

Enrolling by invitation

Predicting Cardiometabolic Risk in Mild-to-Moderate Obstructive Sleep Apnea: Inflammation vs. Apnea/Hypopnea Index

Obstructive Sleep Apnea

United States
Region Västerbotten
Umeå University; Interreg

Enrolling by invitation

Different Forms of OMT as Methods for Reducing Snoring and Mild to Moderate Sleep Apnea (SNORT)

Sleep Apnea, Obstructive | Snoring

Denmark, Sweden
Columbia University
National Heart, Lung, and Blood Institute (NHLBI); NYU Langone Health

Completed

Impact of Sleep Restriction on Performance in Adults

Obesity | Sleep | Sleep Restriction

United States
Sanofi
Regeneron Pharmaceuticals

Active, not recruiting

Pivotal Study to Assess the Efficacy, Safety and Tolerability of Dupilumab in Patients With Moderate to Severe COPD With Type 2 Inflammation (NOTUS)

Chronic Obstructive Pulmonary Disease

Greece, Belgium, Spain, Argentina, Hungary, South Africa, United Kingdom, France, Latvia, Germany, Netherlands, Russian Federation, Ukraine, United States, Australia, Brazil, Bulgaria, Canada, Chile, Colombia, Czechia, Lithuania, Me... and more
Nanoscope Therapeutics Inc.

Completed

Efficacy and Safety of MCO-010 Optogenetic Therapy in Adults With Retinitis Pigmentosa [RESTORE] (RESTORE)

Eye Diseases | Retinal Degeneration | Retinal Diseases | Retinitis Pigmentosa | Retinitis | Eye Diseases, Hereditary | Retinal Dystrophies

United States, Puerto Rico
UCB Biopharma SRL

Completed

A Study to Evaluate the Efficacy and Safety of Bimekizumab in Adult Korean Study Participants With Moderate to Severe Plaque Psoriasis

Moderate to Severe Plaque Psoriasis

Korea, Republic of
Epizyme, Inc.

No longer available

Tazemetostat Expanded Access Program for Adults With Solid Tumors

Renal Cell Carcinoma | Malignant Mesothelioma | Chondrosarcoma | Synovial Sarcoma | Renal Medullary Carcinoma | Malignant Rhabdoid Tumor | Poorly Differentiated Chordoma | Malignant Rhabdoid Tumor of Ovary | Epithelioid Malignant Peripheral Nerve Sheath Tumor | Sinonasal Carcinoma | Spindle Cell Sarcoma | Epithelioid... and other conditions
National Cheng-Kung University Hospital

Completed

The Influences of Intervention With Home-based Recovery Activity in Obstructive Sleep Apnea Syndrome (OSAS)

Obstructive Sleep Apnea

Taiwan
Novartis Pharmaceuticals

Completed

A Prospective Multicenter Study for the Assessment of Treatment Patterns, Effectiveness and Safety of Secukinumab in Adult Patients With Moderate to Severe Plaque Psoriasis in a Real-world Setting in China (UNMASK2)

Psoriasis

China
Fundación Pública Andaluza para la gestión de la...

Active, not recruiting

Study to Compare Clozapine vs Treatment as Usual in People With Intellectual Disability & Treatment-resistant Psychosis (CLOZ-AID)

Intellectual Disability | Psychosis

Spain
National Cancer Institute (NCI)

Completed

Tipifarnib in Treating Patients With Acute Myeloid Leukemia in Remission

Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Recurrent Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia in Remission | Myelodysplastic Syndrome With Excess Blasts | Adult Acute Monocytic Leukemia | Adult Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11 and other conditions

United States, Israel, Peru
FibroGen

Terminated

Zephyrus I: Evaluation of Efficacy and Safety of Pamrevlumab in Participants With Idiopathic Pulmonary Fibrosis (IPF)

Idiopathic Pulmonary Fibrosis

United States, China, Australia, Korea, Republic of, Taiwan, Russian Federation, Hong Kong, Argentina, Chile
AbbVie

Completed

A Study to Compare Safety and Efficacy of Upadacitinib to Dupilumab in Adult Participants With Moderate to Severe Atopic Dermatitis (Heads Up)

Atopic Dermatitis

United States, Australia, Canada, Croatia, Czechia, Finland, France, Germany, Hungary, Ireland, Israel, Italy, Malaysia, Netherlands, New Zealand, Norway, Poland, Singapore, Spain, Sweden, Taiwan, Ukraine, United Kingdom
Clinica Universidad de Navarra, Universidad de...
Hospital Clinic of Barcelona; Hospital Son Espases; Hospital del Mar; Hospital... and other collaborators

Active, not recruiting

Predictive Model to Calculate the Risk of RBC Transfusion in Elective Brain Tumours Resections (TScoreBTR) (TScoreBTR)

Surgery | Brain Tumor Adult | Transfusion

Spain
University of California, San Diego
National Institutes of Health (NIH); Small Steps Labs, LLC

Completed

SMART 2.0: Social Mobile Approaches to Reducing weighT in Young Adults (SMART 2)

Overweight and Obesity

United States
Washington University School of Medicine
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National...

Completed

A Clinical Trial of Dantrolene Sodium in Pediatric and Adult Patients With Wolfram Syndrome

Diabetes Mellitus | Ataxia | Wolfram Syndrome | Optic Nerve Atrophy

United States
University of New Mexico
Patient-Centered Outcomes Research Institute; Montana State University; National... and other collaborators

Terminated

Longitudinal Comparative Effectiveness of Bipolar Disorder Therapies

Bipolar Disorder

United States
Lakshmi Nutraceuticals LLC
People Science, Inc.

Completed

Combined Effects of Prunus Cerasus and Apocynum Venetum On Sleep and Anxiety in Adults With Insomnia (Sip2Sleep)

Insomnia

United States
Sanofi

Completed

Proof of Concept Study of Rilzabrutinib in Adult Participants With Moderate-to-severe Asthma

Asthma

Spain, Korea, Republic of, Chile, Mexico, United Kingdom, Argentina, Bulgaria, Canada, Hungary, Poland, Romania, Turkey, Germany
Karolinska Institutet
Karolinska University Hospital

Active, not recruiting

Exercise Intolerance in Post-COVID Patients (EXILE)

Post-COVID Syndrome

Sweden
Wright State University

Completed

Defining N-Acetyl Cysteine as a Treatment for Inhibiting Prurogenic Stimuli

Pruritus | Skin Disorder

United States
AbbVie

Active, not recruiting

Evaluation of Upadacitinib in Adolescent and Adult Patients With Moderate to Severe Atopic Dermatitis (Eczema) (Measure Up 1)

Atopic Dermatitis

United States, Argentina, Australia, Bosnia and Herzegovina, Bulgaria, Canada, China, Colombia, Croatia, Denmark, Estonia, Finland, France, Germany, Italy, Japan, Malaysia, New Zealand, Puerto Rico, Romania, Russian Federation, Sw... and more
AbbVie

Active, not recruiting

A Study to Evaluate Upadacitinib in Adolescents and Adults With Moderate to Severe Atopic Dermatitis (Measure Up 2)

Atopic Dermatitis

United States, Australia, Austria, Belgium, Bulgaria, Canada, Croatia, Czechia, Denmark, France, Germany, Greece, Hungary, Ireland, Italy, Korea, Republic of, Netherlands, New Zealand, Portugal, Singapore, Spain, Taiwan, United Kingdom
Pfizer

Active, not recruiting

Study to Evaluate the Efficacy and Safety of PF-07055480 / Giroctocogene Fitelparvovec Gene Therapy in Moderately Severe to Severe Hemophilia A Adults (AFFINE)

Hemophilia A

Spain, Taiwan, Australia, United States, Japan, France, Turkey, Germany, Korea, Republic of, United Kingdom, Saudi Arabia, Canada, Greece, Sweden, Brazil, Italy
Novartis Pharmaceuticals

Active, not recruiting

2 Years Prospective Study to Collect Real-life Data on the Retention, Quality of Life, Effectiveness and Treatment Pattern of Secukinumab in Adult Patients With Moderate to Severe Plaque Psoriasis, Psoriatic Arthritis, Ankylosing Spondylitis and Non-radiographic Axial Spondyloarthritis (PROMPT)

Psoriatic Arthritis | Ankylosing Spondylitis | Moderate to Severe Plaque Psoriasis | Non-radiographic Axial Spondyloarthritis

Thailand

Search clinical trials for: Adult moderate to serve SLE

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