Clinical Trials Sponsored by Heart Initiative

Total 7230 results

Imperial College London
National Heart Foundation, Australia; Royal Brompton & Harefield NHS Foundation... and other collaborators

Completed

Radial Artery Versus Saphenous Vein Patency (RSVP) Study (RSVP)

Coronary Arteriosclerosis

United Kingdom
The George Washington University Biostatistics...
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Combined Antioxidant and Preeclampsia Prediction Studies (CAPPS) (CAPPS)

Preeclampsia

United States
Kaiser Permanente
National Heart, Lung, and Blood Institute (NHLBI); Oregon Health and Science... and other collaborators

Completed

Dissemination of CVD Risk Factor Treatment Among Diabetic Patients in Safety Net Clinics (ALL)

Cardiovascular Diseases | Diabetes Mellitus
Catholic University of the Sacred Heart
University Hospital, Geneva; Universiteit Antwerpen; Clinical Centre of Serbia; Canisius-Wilhelmina Hospital and other collaborators

Unknown

SATURN 04 Nosocomial Acquisition Study (SATURN)

Infection Due to ESBL Bacteria | Bacterial Resistance | Infection Resistant to Multiple Drugs | Staph Aureus Methicillin Resistant Colonization

Italy, Romania, Serbia
Singapore General Hospital
National University Hospital, Singapore; Tan Tock Seng Hospital; Medtronic; Changi... and other collaborators

Unknown

High Low Biphasic Energy Defibrillation (HiLoBED)

Ventricular Fibrillation

Singapore
Clinton Health Access Initiative Inc.
University of Amsterdam; Harvard School of Public Health (HSPH); Ministry of... and other collaborators

Completed

MaxART: Early Access to ART for All in Swaziland (MaxART)

HIV/AIDS

Swaziland
University of Toronto
University of Manitoba; University Health Network, Toronto; University of Alberta and other collaborators

Not yet recruiting

TIME™ at Home Randomized Controlled Trial

Mobility Limitation
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Recruiting

Treosulfan-Based Conditioning Regimen Before a Blood or Bone Marrow Transplant for the Treatment of Bone Marrow Failure Diseases (BMT CTN 1904)

Congenital Amegakaryocytic Thrombocytopenia | Paroxysmal Nocturnal Hemoglobinuria | Diamond-Blackfan Anemia | Shwachman-Diamond Syndrome | Bone Marrow Failure Syndrome | Hereditary Sideroblastic Anemia | Hematologic Neoplasm With Germline GATA2 Mutation | Hematologic Neoplasm With Germline SAMD9... and other conditions

United States
University of California, San Francisco
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Recruiting

Short-Term Cardiovascular Effects of E-Cigarettes: Influence of E-Liquid pH (TCORS-2)

Cardiovascular Risk Factor | Nicotine Dependence

United States
UMC Utrecht
Maastricht University Medical Center; Academisch Medisch Centrum - Universiteit... and other collaborators

Recruiting

Dutch-AMR: Early Mitral Valve Repair Versus Watchful Waiting in Asymptomatic Patients With Severe Mitral Regurgitation (Dutch-AMR)

Mitral Regurgitation

Netherlands
University of California, San Francisco
National Heart, Lung, and Blood Institute (NHLBI); Northwestern University; New... and other collaborators

Recruiting

Mediators of Atherosclerosis in South Asians Living in America (MASALA)

Heart Diseases | Cardiovascular Diseases | Coronary Artery Disease | Coronary Disease | Atherosclerosis

United States
University of Minnesota
National Heart, Lung, and Blood Institute (NHLBI); Syracuse University; Liverpool... and other collaborators

Completed

Bloodsafe Ghana- Iron and Nutritional Counseling Strategy Pilot Study (BLIS)

Iron-deficiency | Iron-deficiency Anemia

Ghana
McMaster University
Hamilton Health Sciences Corporation; Ontario Ministry of Health and Long Term... and other collaborators

Completed

Optimizing Hospital-to-home Transitions for Older Adults With Stroke and Multimorbidity

Stroke

Canada
Medical College of Wisconsin
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

Bone Marrow Transplant From Partially Matched Donors and Nonmyeloablative Conditioning for Blood Cancers (BMT CTN 0603)

Lymphoma, Follicular | Lymphoma, B-Cell | Lymphoma, Large B-Cell, Diffuse | Leukemia, Myeloid, Acute | Burkitt Lymphoma | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma

United States
Medical College of Wisconsin
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

Prospective Cohort for the Evaluation of Biomarkers Following HCT (BMT CTN 1202)

Allogeneic Hematopoietic Stem Cell Transplantation

United States
Nova Scotia Health Authority
AstraZeneca; Heart and Stroke Foundation of Canada; Atlantic Health Sciences... and other collaborators

Completed

A Strategy of Home Telehealth for Management of Congestive Heart Failure(STARTEL)

Heart Failure

Canada
Medical College of Wisconsin
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

Fludarabine-based Conditioning for Severe Aplastic Anemia (BMT CTN 0301)

Anemia, Aplastic

United States
Medical College of Wisconsin
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

Single vs Double Umbilical Cord Blood Transplants in Children With High Risk Leukemia and Myelodysplasia (BMT CTN 0501)

Myelodysplastic Syndrome | Acute Lymphocytic Leukemia | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia | Natural Killer Cell Lymphoblastic Leukemia/Lymphoma

United States, Australia, Canada
Children's Hospital of Philadelphia
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

The ICU-Resuscitation Project (ICU-RESUS) (ICU-RESUS)

Cardiac Arrest

United States
Washington University School of Medicine
National Heart, Lung, and Blood Institute (NHLBI); Canadian Institutes of Health... and other collaborators

Completed

Age of Blood in Children in Pediatric Intensive Care Units (ABC-PICU)

Anemia

United States, Canada, France, Israel, Italy
Beijing Institute of Heart, Lung and Blood Vessel...
The First Hospital of Jilin University; The First Affiliated Hospital of Dalian... and other collaborators

Unknown

Diagnosis and Prognosis for Aortic Aneurysm aNd Dissection in Anzhen(DPANDA) Study

Aortic Aneurysm | Aortic Dissection

China
Joshua M Hare
National Heart, Lung, and Blood Institute (NHLBI); The Emmes Company, LLC; Johns...

Terminated

Prospective Randomized Study of Mesenchymal Stem Cell Therapy in Patients Undergoing Cardiac Surgery (PROMETHEUS) (PROMETHEUS)

Stem Cell Transplantation | Ventricular Dysfunction, Left

United States
Cedars-Sinai Medical Center
National Heart, Lung, and Blood Institute (NHLBI); University of California... and other collaborators

Completed

Cut Your Pressure Too: The Los Angeles Barbershop Blood Pressure Study

Hypertension

United States
Michael A. Matthay
Massachusetts General Hospital; National Heart, Lung, and Blood Institute (NHLBI) and other collaborators

Completed

Human Mesenchymal Stem Cells For Acute Respiratory Distress Syndrome (START)

Acute Respiratory Distress Syndrome

United States
Baylor College of Medicine
National Heart, Lung, and Blood Institute (NHLBI); The Methodist Hospital Research... and other collaborators

Completed

Administration of Virus-Specific Cytotoxic T-Lymphocytes (LYPTAIST)

Adenovirus Infection

United States
Molecular Targeting Technologies, Inc.
National Heart, Lung, and Blood Institute (NHLBI); Yale University; University... and other collaborators

Completed

Study of 99mTc-glucarate to Detect Acute Coronary Syndrome in Chest Pain Patients.

Acute Coronary Syndrome

United States
University of Illinois at Chicago
Patient-Centered Outcomes Research Institute; American Heart Association; University... and other collaborators

Completed

PATient Navigator to rEduce Readmissions (PArTNER)

Myocardial Infarction | Heart Failure | Pneumonia | Chronic Obstructive Pulmonary Disease | Sickle Cell Disease

United States
Finnish Institute for Health and Welfare
University of Helsinki; Tampere University; The Finnish Hearth Association; The...

Completed

Lifestyle Intervention for Toddlers Pilot Study (LIFT)

Obesity

Finland
Nationwide Children's Hospital
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health... and other collaborators

Not yet recruiting

Applying Directly Observed Therapy to Hydroxyurea to Realize Effectiveness (ADHERE)

Sickle Cell Disease

United States
Gachon University Gil Medical Center
Hallym University Medical Center; Hallym University Kangnam Sacred Heart Hospital and other collaborators

Recruiting

Concomitant Intranasal Antihistamine and Corticosteroid in Stepwise Treatment Strategy for Allergic Rhinitis (INCS/INAH)

Allergic Rhinitis

Korea, Republic of
Medical University of Silesia
Silesian University of Technology; Liverpool Centre for Cardiovascular Science...

Recruiting

Cardiovascular Disease in Patients With Diabetes: The Silesia Diabetes-Heart Project

Diabetes Mellitus

Poland
Palo Alto Medical Foundation
National Heart, Lung, and Blood Institute (NHLBI); University of Pittsburgh; University... and other collaborators

Completed

Research Aimed at Improving Both Mood and Weight (RAINBOW-ENGAGE)

Depression | Obesity

United States
Medical College of Wisconsin
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

TAC/MTX vs. TAC/MMF/PTCY for Prevention of Graft-versus-Host Disease and Microbiome and Immune Reconstitution Study (BMT CTN 1703/1801) (1703/1801)

Lymphoma | Acute Leukemia | Myelodysplasia | Chronic Myelogenous Leukemia (CML)

United States
Medical College of Wisconsin
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Active, not recruiting

Haploidentical Bone Marrow Transplantation in Sickle Cell Patients (BMTCTN1507)

Sickle Cell Disease

United States
Medical College of Wisconsin
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Terminated

Autologous or Donor Stem Cell Transplantation in Treating Patients With Recurrent Non-Hodgkin's Lymphoma (BMT CTN 0202)

Follicular Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma

United States
Medical College of Wisconsin
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

Peripheral Blood Stem Cell Transplant vs Bone Marrow Transplant in Individuals With Hematologic Cancers (BMT CTN 0201)

Leukemia | Myeloproliferative Disorders | Myelodysplastic-Myeloproliferative Diseases

United States, Canada
Medical College of Wisconsin
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

Comparison of Fluconazole vs Voriconazole to Treat Fungal Infections for Blood and Marrow Transplants (BMT CTN 0101)

Lymphoma | Leukemia | Infection

United States
Medical College of Wisconsin
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

Autologous Transplant in HIV Patients (BMT CTN 0803)

Lymphoma | HIV

United States
Medical College of Wisconsin
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

Blood Stem Cell Transplant With Low Dose Chemotherapy for Relapsed Follicular Non-Hodgkin's Lymphoma (BMT CTN 0701)

Lymphoma, Non-Hodgkin

United States
Medical College of Wisconsin
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

Reduced Intensity Conditioning for Hemophagocytic Syndromes or Selected Primary Immune Deficiencies (BMT CTN 1204) (RICHI)

Chronic Granulomatous Disease | Hemophagocytic Lymphohistiocytosis | Leukocyte Adhesion Deficiency | Chronic Active Epstein-Barr Virus Infection | HIGM-1 | IPEX

United States, Canada
Medical College of Wisconsin
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

Easy-to-Read Informed Consent (ETRIC) for Hematopoietic Cell Transplantation Clinical Trials (BMT CTN 1205)

Improve the Informed Consent Process

United States
Medical College of Wisconsin
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

Exercise and Stress Management Post Autologous and Allogeneic Transplant (BMT CTN 0902)

Physiological Stress

United States
Medical College of Wisconsin
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

Optimizing Haploidentical Aplastic Anemia Transplantation (BMT CTN 1502) (CHAMP)

Severe Aplastic Anemia

United States
Massachusetts General Hospital
University of Colorado, Denver; National Heart, Lung, and Blood Institute (NHLBI) and other collaborators

Unknown

Using Videos to Facilitate Advance Care Planning for Patients With Heart Failure (VIDEO-HF)

CHF

United States
The University of Texas Health Science Center,...
National Heart, Lung, and Blood Institute (NHLBI); Center for Cell and Gene... and other collaborators

Completed

Patients With Intermittent Claudication Injected With ALDH Bright Cells (PACE)

Intermittent Claudication | Peripheral Artery Disease

United States
National Heart, Lung, and Blood Institute (NHLBI)
National Cancer Institute (NCI); National Institute of Arthritis and Musculoskeletal... and other collaborators

Completed

Women's Health Initiative (WHI)

Myocardial Ischemia | Heart Diseases | Cardiovascular Diseases | Coronary Disease | Breast Neoplasms | Bone Diseases | Osteoporosis | Colonic Neoplasms | Postmenopause
Centre hospitalier de l'Université de Montréal...
Canadian Institutes of Health Research (CIHR); Montreal Heart Institute; Centre...

Terminated

Antidepressants to Promote Recovery of Cardiac Patients Suffering From Depression (ARCADE)

Acute Coronary Syndrome | Major Depressive Episode

Canada
Eunice Kennedy Shriver National Institute of Child...
National Heart, Lung, and Blood Institute (NHLBI); Office of Research on Women...

Completed

Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-be (nuMoM2b)

Pregnancy Complications | Pregnancy

United States
Liverpool John Moores University
Liverpool Heart and Chest Hospital NHS Foundation Trust; University Hospitals... and other collaborators

Recruiting

Mobile Health for Cardiac Rehabilitation (Motivate-CR+)

Cardiac Event

United Kingdom
National University of Ireland, Galway, Ireland
Karolinska University Hospital; Galway University Hospitals; Kerckhoff Heart... and other collaborators

Enrolling by invitation

Feasibility, Safety, and Effectiveness of the ACURATE neo2 Transcatheter Heart Valve for Severe Bicuspid Aortic Stenosis (Neo2BAV)

Aortic Stenosis | Transcatheter Aortic Valve Replacement | Bicuspid Aortic Valve | Transcatheter Aortic Valve Implantation

Sweden, Ireland, Germany

Clinical Trials Sponsored by Heart Initiative

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