Search clinical trials for: intravenous acetaminophen

Total 7478 results

All India Institute of Medical Sciences, New Delhi

Completed

Comparison of Three Different Treatment Regimes in Early Rheumatoid Arthritis: A Randomized Open-labelled Trial

Rheumatoid Arthritis

India
University of Puerto Rico

Completed

Multi-Modal Anesthesia Protocol in Pain Management of Patients Undergoing Posterior Lumbar Spinal Fusion Surgery

Pain Management | Posterior Spinal Fusion

Puerto Rico
National Institute of Allergy and Infectious Diseases...
Rho Federal Systems Division, Inc.

Terminated

Donor-Alloantigen-Reactive Regulatory T Cell (darTregs) in Liver Transplantation (deLTa)

Liver Transplantation

United States
University of Wisconsin, Madison
Immune Tolerance Network (ITN)

Completed

Combination Immunosuppressive Therapy to Prevent Kidney Transplant Rejection in Adults

Kidney Transplantation | Kidney Disease

United States
University of Milano Bicocca
Azienda Ospedaliera Universitaria Integrata Verona; Azienda Socio Sanitaria... and other collaborators

Recruiting

Dual Anti-glutamate Therapy in Super-refractory Status Epilepticus After Cardiac Arrest (SUPER-CAT)

Cardiac Arrest | Status Epilepticus

Italy
Mirati Therapeutics Inc.

Completed

PK Study to Assess Drug-drug Interaction and QTc Between Sitravatinib and a Cocktail of Substrates

Advanced Solid Tumor

United States
Amgen

Active, not recruiting

Study to Investigate the Effect of Rocatinlimab (AMG 451) on the Pharmacokinetics of Multiple Cytochrome P450 (CYP450) Substrates in Participants With Moderate to Severe Atopic Dermatitis

Atopic Dermatitis

United States
GlaxoSmithKline

Completed

Drug-drug Interaction Study of Gepotidacin

Infections, Bacterial

United States
Novartis Pharmaceuticals

Withdrawn

HDM201 Added to CT in R/R or Newly Diagnosed AML

Leukemia, Myeloid, Acute
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Effect of Ibrutinib on the Pharmacokinetics of Oral Contraceptives, CYP2B6, and CYP3A4 Substrates in Female Participants With B Cell Malignancy

Leukemia, Lymphocytic, Chronic, B-Cell

Spain, Poland
HTL-Strefa S.A.

Completed

Characteristics of Different Types of Safety Lancets on Blood Volume and Perceived Pain in Male and Female Volunteers

Healthy

Poland
Bristol-Myers Squibb

Completed

A Study to Assess the Effect of BMS-986142 on Pharmacokinetics (PK) of Probe Substrates

Rheumatoid Arthritis

United States
New York State Psychiatric Institute

Completed

NMDA Antagonists in Bipolar Depression

Bipolar Disorder

United States
Boehringer Ingelheim

Completed

The Effect of BI 187004 on the Pharmacokinetics of Cytochrome P450 Substrates (Caffeine, Warfarin, Omeprazole, Metoprolol and Midazolam) and a P Glycoprotein Substrate (Digoxin)

Healthy

Germany
AstraZeneca

Completed

A Phase I Study in Healthy Volunteers to Assess the Effect of Cytochrome3A4 (CYP3A4) Inhibitors (Diltiazem and Itraconazole) on the Pharmacokinetics (PK) of AZD3293 and the Effects of AZD3293 on the Pharmacokinetics of Midazolam, a Cytochrome 3A4 and Cytochrome 3A5 (CYP3A4/CYP3A5) Substrate (AZD3293DDI)

Healthy Volunteers | Pharmacologic Action

United States
Aga Khan University

Recruiting

Analgesic Efficacy of Ropivacaine Alone or in Combination With Adjuvants on Post-operative Analgesia Following Video-Assisted Thoracoscopic Surgery.

Postoperative Analgesia

Pakistan
University of Arkansas
National Institute on Drug Abuse (NIDA)

Completed

Drug Discrimination in Methadone-Maintained Humans Study 3 (OMDD3)

Drug Dependence

United States
GlaxoSmithKline

Completed

Drug Interaction Study of Darunavir/Ritonavir and Lopinavir/Ritonavir on GSK2248761 PK and CYP450 Probe Drugs

Healthy Subjects | Infection, Human Immunodeficiency Virus

United States
Bristol-Myers Squibb

Completed

Drug Interaction Study With a Potential Alzheimer's Disease Compound

Alzheimer Disease

United States
DICE Therapeutics, Inc., a wholly owned subsidiary...
Eli Lilly and Company

Recruiting

A Study to Assess LY4100511 (DC-853) in Healthy Adult Participants

Healthy

United States
Zagazig University

Completed

Evidence Based Management of Acute Biliary Pancreatitis

Acute Pancreatitis

Egypt
Ain Shams University

Not yet recruiting

Quality of Recovery After Laparoscopic Cholecystectomy Comparing Opioid Free Analgesia Versus Opioid Free Anesthesia

Pain, Postoperative | Quality of Recovery | Elective Laparoscopic Cholecystectomy

Egypt
Janssen Research & Development, LLC

Suspended

A Study to Evaluate the Effect of Ustekinumab on Cytochrome P450 Enzyme Activities Following Induction and Maintenance Dosing in Participants With Active Crohn's Disease or Ulcerative Colitis

Crohn Disease | Ulcerative Colitis

Germany, United States, United Kingdom, Belgium
Institut fuer anwendungsorientierte Forschung und...

Completed

Repeated Dose Study for the Investigation of Heritability of and Genetic Influences on Drug Pharmacokinetics

Membrane Transport | Drug Biotransformation

Germany
Korea University

Completed

Comparative Study of Nonintubated Anesthesia Versus Intubated General Anesthesia in Single Port Thoracoscopic Bullectomy

Primary Spontaneous Pneumothorax

Korea, Republic of
Monica Bhatia

Active, not recruiting

Abatacept for GVHD Prophylaxis After Hematopoietic Stem Cell Transplantation for Pediatric Sickle Cell Disease

Sickle Cell Disease | Graft Versus Host Disease

United States
Medical University of Warsaw

Recruiting

Opioid Free vs Opioid Based Anesthesia for Laparoscopic Sleeve Gastrectomy

Obesity | Postoperative Pain | Opioid Use | Postoperative Nausea | Postoperative Vomiting

Poland
Dr M. B. Breebaart

Recruiting

Lumbar Erector Spinae Plane Block for Back Surgery (LUMBES)

Pain, Postoperative | Back Pain | Anaesthesia | Anesthesia, Local | Surgery | Spinal Fusion | Nerve Block

Belgium
Theodor Bilharz Research Institute

Completed

Dexmedetomidine and Desflurane Consumption

Anesthesia

Egypt
Boehringer Ingelheim

Completed

Study to Evaluate the Effect of Multiple Doses of BIRT 2584 XX Tablets on the Pharmacokinetic Parameters of Warfarin, Omeprazole, Caffeine, and Dextromethorphan in Healthy Male Volunteers

Healthy
Tang-Du Hospital

Unknown

Effects and Mechanism of Pretreatment With Dexmedetomidine to Etomidate Induce Myoclonus

Myoclonus
ASIS Corporation

Unknown

ASIS for GAMMAGARD in Primary Immunodeficiency (ASISinPI)

Primary Immunodeficiency

United States
Università Vita-Salute San Raffaele
Ospedale San Raffaele

Completed

Safety and Feasibility Study of Enhanced Recovery in Pancreaticoduodenectomy

Pancreatic Neoplasms

Italy
Seoul National University Hospital

Completed

Identification and Evaluation of Endogenous Markers for the Assessment of CYP3A Activity

Healthy

Korea, Republic of
MEDSI Clinical Hospital 1, ICU

Recruiting

Efficacy and Safety of Selective Digestive Decontamination in the ICU With High Rates of Antibiotic-resistant Bacteria

Respiratory Tract Infections | Pneumonia | Sepsis | Critical Illness | Respiratory Distress Syndrome | Pneumonia, Ventilator-Associated | Bloodstream Infection

Russian Federation
Guangdong Raynovent Biotech Co., Ltd

Completed

Drug-durg Interaction of Leritrelvir(RAY1216) With Midazolam, Omeprazole, Rosuvastatin, Verapamil, and Rifampin

Drug Drug Interaction

China
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Drug-drug Interaction Study Of Fluzoparib (SHR3162) on Patients With Recurrent Ovarian Cancer

Recurrent Ovarian Cancer

China
Natalia Valadares de Moraes
University of Sao Paulo; Fundação de Amparo à Pesquisa do Estado de São Paulo

Enrolling by invitation

Impact of Bariatric Surgery on Pharmacokinetic Study of Simvastatin and Carvedilol

Obesity | Bariatric Surgery | Roux-en Y Gastric Bypass

United States
University of Debrecen

Completed

Diclofenac Premedication, as the Effect of Preemptive Analgesia After Post-thoracotomy Chest and Shoulder Pain

Pain | Inadequate or Impaired Respiratory Function

Hungary
Seagen Inc.
Millennium Pharmaceuticals, Inc.

Completed

Clinical Pharmacology Study of Brentuximab Vedotin (SGN-35)

Neoplasms | Lymphoma, Non-Hodgkin | Lymphoma, Large-Cell, Anaplastic | Disease, Hodgkin | Carcinomas

United States
University of Patras

Unknown

Epidural Volume Extension and Intrathecal Use of Local Anesthetics in Cesarean Sections

Stillborn Caesarean Section

Greece
Bristol-Myers Squibb

Completed

A Study to Assess the Effect of BMS-986419 on the Single Dose Drug Levels of Probe Substrates in Healthy Participants

Healthy Volunteers

United States
Bristol-Myers Squibb

Completed

A Study to Evaluate the Drug-drug Interaction Potential of BMS-986196 in Healthy Participants

Healthy Volunteers

United States
Amgen

Completed

A Study in Healthy Volunteers to Evaluate the Drug-Drug Interaction Potential of CCX168 With Concomitant Medications

Anti-neutrophil Cytoplasmic Antibody-associated Vasculitis

United States
Inje University

Completed

Development of Minidose Inje Cocktail Method for Simultaneous Evaluating Five Cytochrome P450 Isoforms in Human

Healthy
Merck Sharp & Dohme LLC

Completed

Pharmacokinetics of Midazolam, Dabigatran, Pitavastatin, Atorvastatin, and Rosuvastatin in Participants With Renal Insufficiency in the Presence and Absence of Rifampin (MK-0000-386)

Renal Insufficiency

United States
University of Washington
National Institute of General Medical Sciences (NIGMS)

Completed

The Effects of Multiple Dose Fluoxetine and Metabolites on CYP1A2, CYP2C19, CYP2D6 and CYP3A4 Activity (FLUOXETINE)

Healthy Volunteers | Drug-Drug Interaction
Huazhong University of Science and Technology

Unknown

The Epigenetic Modification in OPRM1 on Postoperative Analgesia and Side Effect Induced by Sufentanil

Epigenetics

China
Boehringer Ingelheim

Completed

Effects of BI 201335 NA on Cytochrome P450 and P-glycoprotein Activity Using a Probe Drug Cocktail in Healthy Volunteers

Healthy
Stanford University

Terminated

Phase 2 Poor Risk DLBCL of TLI and ATG Followed by Matched Allogeneic HT as Consolidation to Autologous HCT

Lymphoma, Non-Hodgkin | Diffuse Large B-cell Lymphoma (DLBCL) | Lymphoma, B-cell | Malignant Lymphoma, Non-Hodgkin

United States

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