Clinical Trials Sponsored by BonusBio Group Ltd

Total 881 results

Hunan Cancer Hospital
Henan Cancer Hospital; Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Recruiting

Anlotinib Plus Penpulimab in Advanced Non-Small-Cell Lung Cancer Previously Treated With PD-1/PD-L1 Inhibitors

Non Small Cell Lung Cancer

China
Xianhai Mao
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Recruiting

TQB2450 Plus Anlotinib as Adjuvant Therapy in HCC Patients at High Risk of Recurrence After Resection (ALTER-H006)

Hepatocellular Carcinoma | Adjuvant Therapy

China
Pharming Technologies B.V.
CMIC Co, Ltd. Japan; Labcorp Central Laboratory; Fortrea; Aixial Group

Active, not recruiting

Pediatric Patients Aged 4 to 11 Years With APDS

APDS

United States, Japan, France, Netherlands
Family Planning Associates Medical Group, LTD
Merck Sharp & Dohme LLC; The Cleveland Clinic

Completed

Nexplanon Application Post-Abortion (NAPA) (NAPA)

Contraception | Abortion, Therapeutic

United States
China National Biotec Group Company Limited
Beijing Institute of Biological Products Co Ltd.

Active, not recruiting

A Immuno-bridging and Immunization Schedules Study of COVID-19 Vaccine (Vero Cell), Inactivated (COVID-19)

Covid19

China
China National Biotec Group Company Limited
Beijing Institute of Biological Products Co Ltd.

Completed

Immuno-bridging Study of Inactivated SARS-CoV-2 Vaccine in Healthy Population Aged 3-17 vs Aged 18 Years Old and Above (COVID-19)

COVID-19 | COVID-19 Pneumonia

United Arab Emirates
First Affiliated Hospital Xi'an Jiaotong University
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Active, not recruiting

Anlotinib Combined With TACE in Hepatocellular Carcinoma Patients at High Risk of Post Surgery Recurrence (ALTER-H-004)

Hepatocellular Carcinoma | Anlotinib | TACE

China
Xiangya Hospital of Central South University
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Unknown

Anlotinib Plus Platinum-etoposide in First-line of Extensive-stage Small-cell Lung Cancer

Extensive-stage Small-cell Lung Cancer

China
Nanfang Hospital of Southern Medical University
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Unknown

A Study of Sequential Anlotinib Followed by EP Regimen Plus Concurrent Radiotherapy for Unresectable Stage III Non-small Cell Lung Cancer

Unresectable Stage III Non-small Cell Lung Cancer

China
The Affiliated Hospital of Qingdao University
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Unknown

Anlotinib Combined With Docetaxel for Advanced Non-Small Cell Lung Cancer（ALTER-L034） (ACDFNSCLC)

Non Small Cell Lung Cancer
Sichuan Cancer Hospital and Research Institute
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Unknown

Anlotinib Versus Docetaxel as the Second-line Treatment in EGFR Wild Type Patients With Advanced NSCLC

Lung Cancer | Lung Cancer Metastatic

China
Pharming Technologies B.V.
CMIC Co, Ltd. Japan; Labcorp Central Laboratory; Fortrea; Aixial Group

Recruiting

Pediatric Patients Aged 1 to 6 Years With APDS

APDS

United States, Japan, Spain, United Kingdom, Portugal
Wanbangde Pharmaceutical Group Co., LTD
Second Affiliated Hospital, School of Medicine, Zhejiang University

Not yet recruiting

The Effect of Huperzine A Injection on Postoperative Cognitive Dysfunction in Patients With Aneurysmal Subarachnoid Hemorrhage: a Pilot Study

Postoperative Cognitive Dysfunction in Patients With Aneurysmal Subarachnoid Hemorrhage

China
China National Biotec Group Company Limited
Beijing Institute of Biological Products Co Ltd.

Active, not recruiting

A Phase 3 Study of BIBP Diphtheria, Tetanus and Acellular Pertussis (Three Components) Combined Vaccine, Adsorbed (DTaP)

Whooping Cough | Tetanus | Diphtheria

China
Sun Yat-sen University
Innovent Biologics (Suzhou) Co. Ltd.; CSPC Pharmaceutical Group Limited

Completed

Efficacy and Safety of Preoperative Sintilimab Plus Nab-paclitaxel and Cisplatin in BR-ESCC Patients

Esophageal Squamous Cell Carcinoma

China
Sichuan Cancer Hospital and Research Institute
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Unknown

Efficacy and Safety of Anlotinib Plus Platinum Plus Pemetrexed in T790M-negative NSCLC

Lung Cancer Metastatic

China
The First People's Hospital of Lianyungang
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Unknown

Anlotinib Plus Chemotherapy for Patients With Advanced Non-small Cell Lung Cancer

Lung Neoplasms | Anlotinib | Docetaxel | S-1 | Pemetrexed

China
Cellular Biomedicine Group Ltd.
RenJi Hospital; General Hospital of Chinese Armed Police Force

Completed

Clinical Trial of Autologous Adipose Tissue-Derived Mesenchymal Progenitor Cells (MPCs) Therapy for Knee Osteoarthritis

Knee Osteoarthritis

China
Access Business Group
Fudan University; Sprim Advanced Life Sciences; Sinphar Pharmaceutical Co., Ltd

Completed

Effect of Ginko and Cistanche Against Fatigue Symptoms (GkoCist)

Fatigue | Mental Fatigue | Chronic Fatigue Syndrome
Sinopharm Wuhan Plasma-derived Biotherapies Co....
China National Biotec Group Company Limited; Beijing Tiantan Biological Products...

Not yet recruiting

Human COVID-19 Immunoglobulin (COVID-HIG) Therapy for COVID-19 Patients

COVID-19

United Arab Emirates
Japan Clinical Oncology Group
Taiho Pharmaceutical Co., Ltd.; Ministry of Health, Labour and Welfare, Japan; Yakult Honsha Co., LTD

Completed

A Study of 5-FUci Versus CPT-11 Plus CDDP Versus S-1 Alone in Advanced Gastric Cancer

Gastric Cancer

Japan
Peking University Third Hospital
Beijing Municipal Health Commission; BOE Technology Group Co. Ltd.

Recruiting

Screening and Early Warning of Chronic Obstructive Pulmonary Disease Combined With Sleep Respiratory Disease Based on Medical Internet of Things

COPD | Osa Syndrome

China
The First Hospital of Jilin University
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Unknown

Anlotinib Single Drug as the Maintenance Treatment for Advanced NSCLC

Non-Small Cell Lung Cancer

China
Spanish Cooperative Group for the Treatment of...

Completed

Study of FOLFIRI + Panitumumab Using Ultra-selection Technology of Patients With Stage IV Colorectal Cancer Refractory to Irinotecan Without Any Mutation on KRAS, PIK3Ca, BRAF and NRAS Genes Detected With Highly Sensitive Techniques (ULTRA)

Stage IV Colorectal Cancer

Spain
Spanish Cooperative Group for the Treatment of...

Completed

Safety and Efficacy Study of mFOLFOX-6 Plus Cetuximab for 8 Cycles Followed by mFOLFOX-6 Plus Cetuximab or Single Agent Cetuximab as Maintenance Therapy in Patients With Metastatic Colorectal Cancer and WT KRAS Tumours (MACRO-2)

Metastatic Colorectal Cancer

Spain
Spanish Cooperative Group for the Treatment of...

Completed

Safety and Efficacy Study of XELOX vs. Oxaliplatin+5-FU CI as First Line Treatment in Metastatic Colorectal Cancer

Colorectal Cancer

Spain
Spanish Cooperative Group for the Treatment of...

Terminated

Axitinib as Maintenance Treatment in Patients With Metastatic CRC (TTD-11-01)

Colorectal Carcinoma

Spain
Spanish Cooperative Group for the Treatment of...

Completed

Phase I/II Study of Nab-paclitaxel and Gemcitabine Followed by AG-mFOLFOX in Patients With Metastatic Pancreatic Adenocarcinoma (SEQUENCE)

Metastatic Pancreatic Adenocarcinoma

Spain
Groupe Hospitalier Diaconesses Croix Saint-Simon
Cosmo Artificial Intelligence-AI Ltd

Completed

Performance of Artificial Intelligence in Colonoscopy for Right Colon Polyp Detection (AIRCOP)

Colon Cancer | Colon Polyp | Colon Lesion | Colon Adenocarcinoma

France
German CLL Study Group
AbbVie; Hoffmann-La Roche; Swiss Group for Clinical Cancer Research; Stichting... and other collaborators

Completed

Standard Chemoimmunotherapy (FCR/BR) Versus Rituximab + Venetoclax (RVe) Versus Obinutuzumab (GA101) + Venetoclax (GVe) Versus Obinutuzumab + Ibrutinib + Venetoclax (GIVe) in Fit Patients With Previously Untreated Chronic Lymphocytic Leukemia (CLL) Without Del(17p) or TP53 Mutation (GAIA)

Chronic Lymphocytic Leukemia

Ireland, Germany, Israel, Austria, Belgium, Denmark, Switzerland, Finland, Sweden, Netherlands
First Affiliated Hospital of Wenzhou Medical University
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Recruiting

Anlotinib Capsules in the Treatment for IPF/PF-ILDs

Interstitial Lung Diseases

China
Zhejiang Provincial Center for Disease Control...
China National Biotec Group Company ltd

Completed

Immunogenicity and Safety of the Booster Dose of Polio Vaccine With Different Primary Sequential Schedules in China

Vaccine Reaction | Polio

China
Tianjin Medical University Cancer Institute and...
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Unknown

Study of Anlotinib Combined With Osimertinib as Second-line Treatment in Stage IIIb-IV NSCLC With Confirmed EGFRm and T790M (ALTN-03)

Non Small Cell Lung Cancer

China
Beijing Continent Pharmaceutical Co, Ltd.
Shanghai Genomics, Inc.; GNI-EPS Pharmaceuticals, Inc. (GNI Group)

Unknown

Efficacy and Safety of Pirfenidone in Patient With Systemic Sclerosis-associated Interstitial Lung Disease

Systemic Sclerosis-associated Interstitial Lung Disease (Ssc-ild)

China
Cellular Biomedicine Group Ltd.
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University

Unknown

Clinical Trial to Compare ReJoinTM to Sodium Hyaluronate Injection for Knee Osteoarthritis Cartilage Defects

Knee Osteoarthritis | Defect of Articular Cartilage

China
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Tianjin Medical University Cancer Institute and Hospital

Unknown

To Predict Efficacy by Detecting Circulating Endothelial Cell Subsets and Blood Perfusion Parameters Changes in Vivo Tumor in the Phase II/III Study of Anlotinib in Patients With Advanced Non-small Cell Lung Cancer

Non-small Cell Lung Cancer

China
Chengdu University of Traditional Chinese Medicine
Chongqing Taiji Group of Fuling pharmaceutical Co., LTD

Completed

Multicentre, Randomized, Controlled Trial of Qideng Mingmu Capsule in The Treatment of Diabetic Retinopathy

Diabetic Retinopathy | Diabetic Eye Problems | Retinal Disorders

China
Tianjin Medical University Cancer Institute and...
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Not yet recruiting

Penpulimab-based Combination Neoadjuvant/Adjuvant Therapy for Patients With Resectable Locally Advanced Non-small Cell Lung Cancer: a Phase II Clinical Study (ALTER-L043) (ALTER-L043)

Resectable Locally Advanced Non-small Cell Lung Cancer

China
Tianjin Medical University Cancer Institute and...
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Not yet recruiting

Efficacy and Safety of Anlotinib, Irinotecan and Temozolomide in the Treatment of Refractory or Recurrent Neuroblastoma in Children: an Open, Single Arm, Single Center, Phase II Clinical Study

Refractory or Recurrent Neuroblastoma in Children
Dr. Jurjan Aman
Exvastat Ltd.; Simbec-Orion Group; KABS laboratories

Terminated

Intravenous Imatinib in Mechanically Ventilated COVID-19 Patients (INVENT COVID)

Covid19 | Endothelial Dysfunction | Acute Respiratory Distress Syndrome | ARDS | Pulmonary Edema

Netherlands
The First Affiliated Hospital with Nanjing Medical...
Jiangsu HanSoh Tharmaceutical Group Co., Ltd

Withdrawn

Pemetrexed and S-1 in Combination With Bevacizumab in Refractory Colorectal Cancer

Colorectal Neoplasms

China
Tianjin Medical University Cancer Institute and...
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Completed

Study of Anlotinib Combined With Icotinib as the First-line Treatment in Patients With EGFR Mutation-positive NSCLC (ALTER-L004)

Non Small Cell Lung Cancer

China
Tianjin Medical University Cancer Institute and...
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Not yet recruiting

A Study of Efbemalenograstim Alfa Injection for Stage IIIB or IV NSCLC Recieving Moderate-risk Febrile Neutropenia (FN) Chemotherapy Regimen With Risk Factors

Non Small Cell Lung Cancer

China
University of Ulm
AbbVie; Roche Pharma AG; Janssen-Cilag Ltd.; German CLL Study Group

Completed

Trial of Ibrutinib Plus Venetoclax Plus Obinutuzumab in Patients With CLL (CLL2-GiVe)

Leukemia, Lymphocytic, Chronic

Germany
First Affiliated Hospital Xi'an Jiaotong University
Fudan University; Yangtze River Pharmaceutical Group Co., Ltd.

Unknown

A Low-dose Radiation and Contrast Agent Exposure Protocol for Coronary CTA in Diabetic Patients

Coronary Artery Disease

China
Hunan Cancer Hospital
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.; Hunan Provincial People's...

Unknown

Anlotinib Plus Docetaxel for the Treatment of EGFR Wild-type Advanced Non-small-cell Lung Cancer

Non-small Cell Lung Cancer

China
Xiyuan Hospital of China Academy of Chinese Medical...
Wanbangde Pharmaceutical Group Co., LTD

Unknown

Comparing Ginkgo Biloba Pills and Placebo in the Treatment of Coronary Heart Disease With Impaired Glucose Regulation

Randomized Controlled Trial | Ginkgo Biloba Extract

China
Beijing Continent Pharmaceutical Co, Ltd.
Shanghai Genomics, Inc.; GNI-EPS Pharmaceuticals, Inc. (GNI Group)

Unknown

Safety and Efficacy Study of Pirfenidone to Treat Grade 2 or Above Radiation-induced Lung Injury

Radiation Pneumonitis
Spanish Cooperative Group for the Treatment of...
Bayer

Completed

Study Comparing Different Dose Approaches of Induction Treatment of Regorafenib in MCRC (RE-ARRANGE)

Metastatic Colorectal Cancer

Spain
Spanish Cooperative Group for the Treatment of...
Sanofi

Completed

Phase II Trial to Assess FOLFIRI+Aflibercept Efficacy in Patients With Oxaliplatin-pretreated Metastatic Colorectal Cancer With or Without ACE Polymorphisms (POLAF)

Metastatic Colorectal Cancer

Spain

Clinical Trials Sponsored by BonusBio Group Ltd

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