Search clinical trials for: KRAS G12D (ON)

Total 77916 results

GlaxoSmithKline

Completed

Study of Retigabine Immediate Release as Adjunctive Therapy to Specified Monotherapy Antiepileptic Treatments in Adults With Partial-Onset Seizures (IR)

Epilepsy

Bulgaria, Belgium, Thailand, Denmark, Russian Federation, Italy, Spain, Ukraine, Netherlands, Germany, France, Poland
Janssen R&D Ireland

Completed

A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Etravirine Administered in Combination With Other Antiretroviral Agents in Antiretroviral Treatment-Experienced HIV-1 Infected Patients

Human Immunodeficiency Virus (HIV) Infection

France, Ukraine, United States, Mexico, Romania, South Africa, Peru, Argentina, Puerto Rico, Russian Federation, Guatemala
Janssen Research & Development, LLC

Terminated

A Study Comparing Siltuximab Plus Best Supportive Care to Placebo Plus Best Supportive Care in Anemic Patients With International Prognostic Scoring System Low- or Intermediate-1-Risk Myelodysplastic Syndrome

Myelodysplastic Syndrome

United States, Belgium, Spain, Australia, Sweden, Netherlands, Russian Federation
Hoffmann-La Roche

Completed

A Study of Avastin (Bevacizumab) in Combination With Carboplatin-Based Chemotherapy in Patients With Advanced or Recurrent Non-Squamous Non-Small Cell Lung Cancer.

Non-Small Cell Lung Cancer

Australia, Belgium, France, Italy, Hong Kong, Canada, Denmark, Taiwan, Russian Federation, United Kingdom, Spain, Hungary, Czech Republic, Poland, Germany, Netherlands
Johnson & Johnson Pharmaceutical Research & Development...
Bayer

Completed

An Efficacy and Safety Study for Rivaroxaban in Patients With Acute Coronary Syndrome

Myocardial Infarction | Myocardial Ischemia | Acute Coronary Syndrome | Unstable Angina

United States, France, Poland, Ukraine, United Kingdom, China, Belgium, Germany, Spain, Argentina, Chile, Colombia, Israel, Mexico, Portugal, Bulgaria, India, Malaysia, Romania, Russian Federation, Serbia, Turkey, Korea, Republic of, ... and more
Eli Lilly and Company

Withdrawn

Study of Ixekizumab in Participants With Active Ankylosing Spondylitis (AS) (SPIRIT A1)

Spondylitis, Ankylosing

Spain, United States, Hungary, Belgium, France, Mexico, Netherlands, Poland, Russian Federation, Ukraine, United Kingdom, Canada, Argentina, Germany, Czech Republic
Novartis Pharmaceuticals

Completed

Evaluation of Patient Reported Outcomes in RRMS Patients Candidates for MS Therapy Change and Transitioned to Fingolimod 0.5 mg (EPOC) (EPOC)

Relapsing Remitting Multiple Sclerosis

Russian Federation
Merck KGaA, Darmstadt, Germany

Completed

Oxaliplatin and Cetuximab in First-line Treatment of Metastatic Colorectal Cancer (mCRC) (OPUS)

Neoplasm Metastasis | Colorectal Cancer

France, Italy, Poland, Russian Federation, Spain, Germany, Austria, Belgium, Israel, Romania, Greece, Ukraine, Portugal
Helsinn Healthcare SA

Completed

Efficacy and Safety of Palonosetron Intravenous in Prevention of Chemotherapy Induced Nausea and Vomiting in Pediatric Patients

Chemotherapy-Induced Nausea and Vomiting

United States, Argentina, Poland, Peru, Russian Federation, Germany, Austria, Chile, Ukraine, Bulgaria, Czech Republic, Estonia, France, Hungary, Romania, Serbia
Merck KGaA, Darmstadt, Germany
Merck Quimica Argentina S.A.I.C

Completed

Prevalence of the Mutational Status of V-Ki-ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) in Metastatic Colorectal Cancer (mCRC) in Argentine Patients

Colorectal Neoplasms

Argentina
GlaxoSmithKline

Completed

An Open-label Study of GSK1120212 Compared With Docetaxel in Stage IV KRAS-mutant Non-small Cell Lung Cancer

Lung Cancer, Non-Small Cell

United States, Spain, Korea, Republic of, Netherlands, Greece, France, Italy, Hungary
BHR Pharma, LLC
Syneos Health; PRA Health Sciences

Completed

Efficacy and Safety Study of Intravenous Progesterone in Patients With Severe Traumatic Brain Injury (SyNAPSe)

Brain Injuries

Spain, United States, United Kingdom, Austria, Netherlands, Taiwan, Belgium, Singapore, Israel, Germany, Finland, China, Thailand, Malaysia, France, Hungary, Italy, Czech Republic, Argentina, Romania, Russian Federation
Boehringer Ingelheim

Completed

Efficacy and Safety of Dabigatran Compared to Warfarin for 6 Month Treatment of Acute Symptomatic Venous Thromboembolism (RE-COVER I)

Thromboembolism

United States, Argentina, Australia, Austria, Belgium, Brazil, Canada, Czech Republic, Denmark, France, Germany, Greece, Hungary, India, Israel, Italy, Mexico, Netherlands, New Zealand, Norway, Portugal, Russian Federation, Slovakia, South... and more
Boehringer Ingelheim

Completed

Phase III Study Testing Efficacy & Safety of Oral Dabigatran Etexilate vs Warfarin for 6 m Treatment for Acute Symp Venous Thromboembolism (VTE) (RE-COVER II)

Thromboembolism

United States, Australia, Brazil, Bulgaria, Canada, China, Czech Republic, Denmark, France, Hungary, India, Israel, Italy, Korea, Republic of, Malaysia, Netherlands, New Zealand, Norway, Philippines, Poland, Russian Federation, Si... and more
Boehringer Ingelheim

Completed

Secondary Prevention of Venous Thrombo Embolism (VTE). (RE-MEDY)

Thromboembolism

United States, Argentina, Australia, Austria, Belgium, Brazil, Bulgaria, Canada, China, Czech Republic, Denmark, Finland, France, Germany, Greece, Hungary, India, Israel, Italy, Mexico, Netherlands, New Zealand, Norway, Poland, Portugal, Russian... and more
Centocor, Inc.

Completed

A Safety, Efficacy and Pharmacokinetic Study of Siltuximab (CNTO 328) in Participants With Solid Tumors

Head and Neck Neoplasms | Lung Neoplasms | Colorectal Neoplasms | Pancreatic Neoplasms | Ovarian Neoplasms

United States, France, United Kingdom, Spain, Belgium
Regione Lombardia
Mario Negri Institute for Pharmacological Research; Istituto Clinico Humanitas and other collaborators

Completed

Prognostic Factors for Patients With Advanced Colorectal Cancer Treated With Cetuximab.

Colorectal Cancer

Italy
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study of Docetaxel Monotherapy or DOXIL and Docetaxel in Patients With Advanced Breast Cancer

Breast Cancer

United States, Poland, Ukraine, United Kingdom, Spain, Israel, Bulgaria, Romania, Serbia, South Africa, Russian Federation, Hungary, Lithuania, Netherlands, Latvia, Portugal, Estonia, France
Clovis Oncology, Inc.

Completed

A Study Comparing CO-1.01 With Gemcitabine as First Line Therapy in Patients With Metastatic Pancreatic Adenocarcinoma (LEAP)

Metastatic Pancreatic Adenocarcinoma

United States, Belgium, Canada, Australia, United Kingdom, Germany, Italy, Argentina, Russian Federation, France, Brazil, Sweden, Norway, Netherlands, Ukraine
Tibotec Pharmaceuticals, Ireland

Approved for marketing

TMC114-C226: An Early Access Program to Evaluate the Long-term Safety and Tolerability of TMC114 Combined With a Low Dose of Ritonavir (TMC114/r) With Other Antiretrovirals, for HIV-1 Infected Patients Who Have Failed Multiple Antiretroviral Regimens.

HIV Infections

United States, Belgium, Germany, Taiwan, Spain, Switzerland, Mexico, Slovenia, Malaysia, Turkey, Canada, Netherlands, Denmark, Greece, Sweden, Russian Federation, Czech Republic, Puerto Rico, Thailand, Hungary, Luxembourg, Venezuela
AstraZeneca

Terminated

JUPITER - Crestor 20mg Versus Placebo in Prevention of Cardiovascular (CV) Events

Elevated High-sensitivity C-Reactive Protein (hsCRP)

United States, Brazil, Bulgaria, Poland, Russian Federation, South Africa, United Kingdom, Germany, Estonia, Romania, Denmark, Netherlands, Norway, Canada, Mexico, Belgium, Israel, Puerto Rico, Colombia, Argentina, Venezuela, Panama, Urugu... and more
Meir Medical Center

Unknown

Hair Cortisol in Asthma or Allergic Rhinitis Treated With Topical Corticosteroids

ASTHMA | ALLERGIC RHINITIS

Israel
Anthera Pharmaceuticals

Completed

FRANCIS-ACS Trial: A Study of the Safety and Efficacy of A 002 in Subjects With Acute Coronary Syndromes (FRANCIS-ACS)

Acute Coronary Syndrome

Russian Federation, Georgia, Ukraine
National Cancer Institute (NCI)

Completed

Combination Chemotherapy With or Without Peripheral Stem Cell Transplant in Treating Children With Acute Lymphoblastic Leukemia

Childhood Acute Lymphoblastic Leukemia in Remission | Recurrent Childhood Acute Lymphoblastic Leukemia

United States
Oasmia Pharmaceutical AB

Completed

Study of Paclitaxel in Patients With Ovarian Cancer

Fallopian Tube Cancer | Epithelial Ovarian Cancer | Primary Peritoneal Cancer

Ukraine, Belarus, Belgium, Bulgaria, Croatia, Czech Republic, Denmark, Finland, Hungary, Latvia, Lithuania, Romania, Russian Federation, Serbia, Slovakia, Sweden
Centocor, Inc.
Schering-Plough

Completed

An Effectiveness and Safety Study of Intravenous Golimumab in Patients With Active Rheumatoid Arthritis Despite Treatment With Methotrexate Therapy

Arthritis, Rheumatoid

Australia, Poland, Ukraine, United States, Argentina, Colombia, Mexico, Korea, Republic of, Malaysia, Russian Federation, New Zealand, Hungary, Lithuania
Sanofi

Completed

Evaluation of AVE5026 as Compared to Enoxaparin for the Prevention of Venous Thromboembolism in Patients Undergoing Major Abdominal Surgery (SAVE-ABDO)

Venous Thromboembolism

Belgium, Australia, Denmark, Austria, Greece, Korea, Republic of, Peru, Sweden, Italy, Belarus, India, Romania, Serbia, Slovenia, Germany, Latvia, Lithuania, Ukraine, Russian Federation, Spain, Estonia, Poland, Croatia, South Africa, United... and more
Genzyme, a Sanofi Company

Terminated

Efficacy (Induction of Response/Remission) and Safety Study in Patients With Moderate to Severe Crohn's Disease

Crohn Disease

Israel, United States, Romania, Ukraine, South Africa, Canada, Australia, Bulgaria, Russian Federation, New Zealand, Brazil
Endo Pharmaceuticals

Terminated

Efficacy and Safety Study of Octreotide Implant in Patients With Acromegaly

Acromegaly

United States, Czech Republic, Germany, Hungary, Poland, Russian Federation, Serbia, Slovakia, Spain
WiSP Wissenschaftlicher Service Pharma GmbH
ClinAssess GmbH

Unknown

Carboplatin-based Chemotherapy With or Without Panitumumab in Platinum-sensitive Recurrent Ovarian Cancer (PROVE)

Ovarian Cancer

Germany
Pfizer

Terminated

An Evaluation Of The Effectiveness And Safety Of Anidulafungin Compared To Caspofungin For The Treatment Of Deep Tissue Infection Due To Candida

Candidiasis | Fungemia

Belgium, United States, Canada, Switzerland, Netherlands, Bulgaria, Portugal, Romania, Russian Federation
Pfizer

Terminated

Trial Of CP-751, 871 And Erlotinib In Refractory Lung Cancer (NSCLC)

Carcinoma, Non-Small-Cell Lung | Carcinoma, Squamous Cell | Carcinoma, Large Cell | Carcinoma, Adenosquamous Cell

United States, Bulgaria, Italy, Spain, Ukraine, Belgium, France, Ireland, Korea, Republic of, Poland, Russian Federation, United Kingdom, Hungary, Serbia, Taiwan, Canada, South Africa, Brazil, Romania, Greece, Puerto Rico, Czech Republic and more
Tibotec Pharmaceuticals, Ireland

Completed

TMC114-C211: Trial of an Investigational Protease Inhibitor TMC114 With Ritonavir ("TMC114/r") in HIV-1 Infected Patients Who Have Never Been Treated With Antiretroviral Medications.

HIV

United States, France, United Kingdom, Germany, Taiwan, Spain, Belgium, Chile, Costa Rica, Panama, South Africa, Canada, Greece, Singapore, Argentina, Mexico, Puerto Rico, Austria, Russian Federation, Thailand, Australia, Denmark, S... and more
Janssen Research & Development, LLC

Completed

An Efficacy and Safety Study of Extended-Release (ER) Paliperidone in Adolescent Participants With Schizophrenia

Schizophrenia

Ukraine, United States, Spain, India, Romania, Russian Federation, Slovakia
Hoffmann-La Roche
Genentech, Inc.

Completed

A Study to Evaluate the Efficacy and Safety of Herceptin® (Trastuzumab) in Combination With Arimidex® (Anastrozole) an Aromatase Inhibitor Compared to Arimidex® Alone in Patients With Metastatic Breast Cancer

Breast Cancer

Italy, Spain, Sweden, China, Hong Kong, Canada, South Africa, Ukraine, United States, United Kingdom, Russian Federation, Taiwan, Australia, Mexico, Turkey, Israel, Poland, Bulgaria, Germany, France, Netherlands, Norway, India, Hungary, Brazi... and more
Arbeitsgemeinschaft medikamentoese Tumortherapie
Amgen

Terminated

Concurrent Induction Chemoimmunotherapy With Epirubicine, Oxaliplatin, Capecitabine and Panitumumab in KRAs Wild-type, Resectable Type II Gastric Adenocarcinoma

KRAS Wild Type | Resectable Type II Gastric Adenocarcinoma

Austria
Celgene Corporation

Terminated

A Study to Assess the Efficacy and Safety of Lenalidomide in Combination With Cetuximab in Pre-treated Patients With KRAS Mutant Colorectal Cancer

Colorectal Cancer

Australia, Belgium, Germany, Italy, Spain, Sweden
AstraZeneca

Completed

Prevalence Study of Gastrointestinal Risk Factors in Patients With Osteoarthritis (OA), Rheumatoid Arthritis (RA) and Ankylosing Spondylitis (AS). (RATIONAL)

Osteoarthritis (OA) | Rheumatoid Arthritis (RA) | Ankylosing Spondylitis (AS)

Mexico, Vietnam, Malaysia, Argentina, Philippines, Korea, Republic of, Venezuela, Colombia, Russian Federation, Thailand
WiSP Wissenschaftlicher Service Pharma GmbH
Gesellschaft fur Medizinische Innovation - Hamatologie und Onkologie mbH

Suspended

Panitumumab Plus Pemetrexed and Cisplatin (PemCisP) Versus PemCis in the First-line Treatment of Patients With Non-small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung

Germany
University of Roma La Sapienza

Unknown

Ranolazine for Improving Symptoms of Palpitations (RYPPLE)

Ischemic Heart Disease
AIO-Studien-gGmbH
iOMEDICO AG

Terminated

Study to Evaluate the Effects of Panitumumab if Combined With Chemotherapy for 2nd Treatment of Colorectal Cancer (VOXEL)

Colorectal Neoplasms

Germany
National Cancer Institute (NCI)

Completed

Combination Chemotherapy in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia

T-cell Childhood Acute Lymphoblastic Leukemia | Untreated Childhood Acute Lymphoblastic Leukemia

United States
Dr.Laurent Mineur
Merck Serono International SA; BESPIM, CHU Nîmes (data analysis)

Unknown

PREMIUM, Observational Study

First Line WT KRAS mCRC

France
H. Lundbeck A/S

Completed

Short-term Study of Combination Treatment of Escitalopram and Gaboxadol in Major Depressive Disorder

Major Depressive Disorder

Austria, Russian Federation
Abbott
Almedis; Scientific Research Institute of Rheumatology, Moscow

Completed

Study to Characterize Demographics, Compliance, Tolerability and Safety in Patients With Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis Prescribed Adalimumab (Humira®) as Part of Routine Clinical Care

Rheumatoid Arthritis | Psoriatic Arthritis | Ankylosing Spondylitis

Russian Federation
AstraZeneca

Completed

A Study to Observe Real-life Allocation of Antipsychotics in Acute Inpatient Management of Schizophrenia (RECONNECT-S)

Schizophrenia

Russian Federation
Vejle Hospital

Completed

Panitumumab and Pegylated Liposomal Doxorubicin for Platinum-Resistant Epithelial Ovarian Cancer With KRAS Wild-type (PaLiDo)

Epithelial Ovarian Cancer

Denmark, Belgium, Sweden, Austria
Agenus Inc.

Completed

Study of Heat Shock Protein-Peptide Complex (HSPPC-96) Versus IL-2/DTIC for Stage IV Melanoma

Malignant Melanoma

United States, Australia, Poland, Ukraine, United Kingdom, Russian Federation, Hungary, Italy, Sweden
Adherex Technologies, Inc.

Unknown

Study of Eniluracil + 5-Fluorouracil (5-FU) + Leucovorin Versus Capecitabine in Metastatic Breast Cancer

Metastatic Breast Cancer

United States, Russian Federation
AstraZeneca
The Cleveland Clinic

Completed

CRESTOR Athero Imaging Head to Head IVUS Study (SATURN)

Coronary Atherosclerosis

United States, France, Italy, Mexico, Russian Federation, Poland, Netherlands, Canada, Argentina, Australia, Belgium, Hungary, Spain, Brazil

Search clinical trials for: KRAS G12D (ON)

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