Search clinical trials for: Haploidentical HSCT

Total 1111 results

Instituto Nacional de Ciencias Medicas y Nutricion...

Unknown

Autologous Hematopoietic Stem Cell Transplantation as Adjuvant Treatment for Triple Negative Breast Cancer Patients

Triple-Negative Invasive Breast Carcinoma | Residual Tumor

Mexico
Instituto Nacional de Ciencias Medicas y Nutricion...

Unknown

Addition of Gemcitabine to Pre Allo-HSCT Conditioning for Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia, Adult

Mexico
Ronald Levy
National Institutes of Health (NIH)

Completed

Phase 1-2 of a CpG-Activated Whole Cell Vaccine Followed by Autologous Immunotransplant for MCL

Lymphoma, Mantle-Cell

United States
Assistance Publique - Hôpitaux de Paris

Unknown

Inflammatory Response to Paramyxovirus Infection in an Ex-vivo Model of Bronchial Epithelial Cells in Allogeneic HSCT Recipients (ALLOVIRO)

Stem Cell Transplantation

France
Northside Hospital, Inc.

Completed

Caregiver Burden and Distress in Hematopoeitic Stem Cell Transplant

Depression | Fatigue | Anxiety | Distress

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Donor Umbilical Cord Blood Transplant in Treating Patients With Hematologic Cancer

Lymphoma | Acute Myeloid Leukemia | Refractory Hodgkin Lymphoma | Recurrent Mantle Cell Lymphoma | Recurrent Marginal Zone Lymphoma | Acute Lymphoblastic Leukemia | Myelodysplastic Syndrome | Chronic Phase Chronic Myelogenous Leukemia | Recurrent Small Lymphocytic Lymphoma | Chronic Myelogenous Leukemia | Refractory Chronic Lymphocytic Leukemia and other conditions

United States
National Institutes of Health Clinical Center (CC)

Completed

Problem-Solving Education for Caregivers and Patients During Stem Cell Transplant

Distress | Hematopoietic Stem Cell Transplantation

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Yttrium-90 Anti-CD45 Monoclonal Antibody BC8 Followed by Donor Stem Cell Transplant in Treating Patients With High-Risk AML, ALL, or MDS

Chronic Myelomonocytic Leukemia | Previously Treated Myelodysplastic Syndrome | Recurrent Adult Acute Myeloid Leukemia | Secondary Acute Myeloid Leukemia | Recurrent Adult Acute Lymphoblastic Leukemia | Refractory Anemia With Excess Blasts

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

90 Y-BC8-DOTA Monoclonal Antibody, Fludarabine Phosphate, and Total-Body Irradiation Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Multiple Myeloma

Plasma Cell Myeloma | Refractory Plasma Cell Myeloma

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Sirolimus, Cyclosporine, and Mycophenolate Mofetil in Preventing Graft-versus-Host Disease in Treating Patients With Blood Cancer Undergoing Donor Peripheral Blood Stem Cell Transplant

Hematopoietic and Lymphoid Cell Neoplasm | Recurrent Hodgkin Lymphoma | Waldenstrom Macroglobulinemia | Mantle Cell Lymphoma | Chronic Lymphocytic Leukemia | Childhood Acute Lymphoblastic Leukemia | Plasma Cell Myeloma | Recurrent Diffuse Large B-Cell Lymphoma | Prolymphocytic Leukemia | Refractory Chronic... and other conditions

United States, Denmark
University of Wisconsin, Madison
Miltenyi Biomedicine GmbH

Terminated

Haploidentical Transplant With NK Cell Infusion for Pediatric Acute Leukemia and Solid Tumors

Leukemia | Solid Tumors

United States
National Institutes of Health Clinical Center (CC)

Completed

Physical and Emotional Health of Caregivers for People Who Have Had Stem Cell Transplants

Stress | Family Caregivers

United States
Stanford University

Completed

Allogeneic Transplantation From Related Haploidentical Donors

Leukemia | MDS | NHL | Graft Versus Host Disease | Blood Cancer | Malignancy | CLL | Hodgkin's Disease

United States
Children's Hospital Medical Center, Cincinnati
Hoxworth Blood Center

Terminated

CD34+ Stem Cell Infusion to Augment Graft Function

Bone Marrow Failure | Waning Donor Chimerism | Waning Immune Function | Primary Immunodeficiency Disease(s)

United States
University of Minnesota

Completed

Adoptive Transfer of Haploidentical Natural Killer Cells and IL-2

HIV

United States
Central Hospital, Nancy, France

Completed

Detection of Sinusoidal Obstruction Syndrome With Ultrasound After Allogeneic HSCT

Sinusoidal Obstruction Syndrome
Imperial College London

Completed

Effect of Fibre Products on Appetite and Weight

Obesity

United Kingdom
University of Wisconsin, Madison
National Cancer Institute (NCI); National Institutes of Health (NIH)

Completed

Biobehavioral Intervention to Enhance Hematopoietic Stem Cell Transplant Recovery

Myelodysplastic Syndromes | Myeloid Leukemia | Multiple Myeloma | Hodgkin Lymphoma | Non-Hodgkin Lymphoma | Plasma Cell Myeloma | Lymphoid Leukemia

United States
Instituto de Investigación Hospital Universitario...
Instituto de Salud Carlos III; Universidad Carlos III Madrid (TERMeG); St John... and other collaborators

Unknown

Safety Study and Preliminary Efficacy of Infusion Haploidentical Mesenchymal Stem Cells Derived From Bone Marrow for Treating Recessive Dystrophic Epidermolysis Bullosa

Epidermolysis Bullosa Dystrophica, Recessive

Spain
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Tacrolimus and Mycophenolate Mofetil With or Without Sirolimus in Preventing Acute Graft-Versus-Host Disease in Patients Who Are Undergoing Donor Stem Cell Transplant for Hematologic Cancer

Previously Treated Myelodysplastic Syndrome | Recurrent Adult Acute Myeloid Leukemia | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma | Recurrent Adult Lymphoblastic... and other conditions

United States, Germany, Denmark
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Graft-Versus-Host Disease Prophylaxis in Treating Patients With Hematologic Malignancies Undergoing Unrelated Donor Peripheral Blood Stem Cell Transplant

Hematopoietic and Lymphoid Cell Neoplasm | Diffuse Large B-Cell Lymphoma | Acute Myeloid Leukemia | Refractory Hodgkin Lymphoma | Waldenstrom Macroglobulinemia | Acute Lymphoblastic Leukemia | Mantle Cell Lymphoma | Chronic Lymphocytic Leukemia | Myelodysplastic Syndrome | Prolymphocytic Leukemia | Refractory... and other conditions

United States, Germany, Denmark
The University of Hong Kong

Completed

VZV Vaccine for Hematopoietic Stem Cell Transplantation (VZIDST)

Varicella Zoster Infection

Hong Kong
Rafic Farah, MD

Completed

Nonmyeloablative Hematopoietic Cell Transplantation (HCT) for Patients With Hematologic Malignancies Using Related, HLA-Haploidentical Donors: A Pilot Trial of Peripheral Blood Stem Cells (PBSC) as the Donor Source

Lymphoma | Leukemia | Myelofibrosis | MDS

United States
Stanford University
Genzyme, a Sanofi Company

Terminated

Allogeneic HCT Using Nonmyeloablative Host Conditioning With TLI & ATG vs SOC in AML

Leukemia | Leukemia, Myeloid | Acute Myeloid Leukemia (AML)

United States
Federal Research Institute of Pediatric Hematology...

Unknown

Plerixafor/G-CSF as Additional Agents for Conditioning Before HSCT in CGD Patients

Chronic Granulomatous Disease

Russian Federation
University of Florida

Completed

UF-BMT-HSCT-001: A Non-Interventional Study Evaluating Diet in HSCT Survivors

Hematopoietic Neoplasm

United States
National Taiwan University Hospital
National Cheng-Kung University Hospital; Far Eastern Memorial Hospital; Tri-Service... and other collaborators

Terminated

Imatinib for Cytomegalovirus Prophylaxis and Treatment After Allogeneic Hematopoietic Stem Cell Transplantation

Patients Who Have Received Allo-HSCT

Taiwan
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Bortezomib and Chemotherapy in Treating Participants With Lymphoid Malignancies Undergoing Stem Cell Transplant

Hematopoietic and Lymphoid Cell Neoplasm | Lymphoma | CD20 Positive | Lymphocytic Neoplasm

United States
Great Ormond Street Hospital for Children NHS Foundation...
Newcastle-upon-Tyne Hospitals NHS Trust

Completed

Treosulfan Pharmacokinetics in Children Undergoing Allogeneic HSCT (TreoPK)

Allogeneic Haematopoietic Stem Cell Transplantation

United Kingdom
Damiano Rondelli, MD

Terminated

SCD-Haplo: Phase II Study of HLA-Haploidentical SCT for Aggressive SCD (SCD-Haplo)

Sickle Cell Disease

United States
Nanfang Hospital of Southern Medical University
Xiangya Hospital of Central South University; Peking University People's Hospital and other collaborators

Completed

Sorafenib for Prophylaxis of Leukemia Relapse in Allo-HSCT Recipients With FLT3-ITD Positive AML

Acute Myeloid Leukemia | Hematopoietic Stem Cell Transplantation

China
Takeda

Completed

Dose Finding Study of Vedolizumab for GvHD in Participants Undergoing Allogeneic HSCT

Allogeneic Hematopoietic Stem Cell Transplantation

United States
European Society for Blood and Marrow Transplantation
European Research Initiative on CLL

Completed

Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) in 17p- Chronic Lymphocytic Leukemia (CLL) (17p-CLL)

CLL

Germany, United Kingdom, Netherlands, Finland, Sweden, Denmark, Israel
Shanghai General Hospital, Shanghai Jiao Tong University...

Unknown

Diagnosis of Lung Complication After Allo-HSCT by Multiple Parameter System Through BAL (SHSYXY-BAL)

Lung Infection | Bronchoalveolar Lavage Fluid
Masonic Cancer Center, University of Minnesota

Completed

Allogeneic Transplantation For Severe Osteopetrosis

Severe Osteopetrosis

United States
Masonic Cancer Center, University of Minnesota

Completed

HSCT for High Risk Inherited Inborn Errors

Wolman Disease | Adrenoleukodystrophy | Metachromatic Leukodystrophy | Sanfilippo Syndrome | GM1 Gangliosidosis | Globoid Cell Leukodystrophy | Tay Sachs Disease | Sandhoffs Disease | I-Cell Disease

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Fludarabine Phosphate, Radiation Therapy, and Rituximab in Treating Patients Who Are Undergoing Donor Stem Cell Transplant Followed by Rituximab for High-Risk Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Chronic Lymphocytic Leukemia | Recurrent Small Lymphocytic Lymphoma | Prolymphocytic Leukemia | Refractory Chronic Lymphocytic Leukemia | Stage III Small Lymphocytic Lymphoma | Stage IV Small Lymphocytic Lymphoma | T-Cell Large Granular Lymphocyte Leukemia | Stage III Chronic Lymphocytic Leukemia | Stage...

United States, Denmark, Italy
Asan Medical Center
Korea Research Institute of Bioscience & Biotechnology

Completed

Haploidentical NK Cells After Pemetrexed in Patients With Stage IV Non-Small Cell Lung Cancer (NSCLC) (Medi-NK)

Non-small Cell Lung Cancer

Korea, Republic of
Asan Medical Center

Terminated

Randomized Study of Haploidentical Hct and Subsequent Donor nk Cell Infusion in High-risk AML and MDS (DNKI-4)

Acute Myelogenous Leukemia

Korea, Republic of
Dana-Farber Cancer Institute
National Cancer Institute (NCI); National Institute of Allergy and Infectious...

Completed

Laboratory-Treated Lymphocyte Infusion After Haploidentical Donor Stem Cell Transplant

Myelodysplastic Syndromes | Leukemia

United States
City of Hope Medical Center

Terminated

Deferasirox for Treating Patients Who Have Undergone Allogeneic Stem Cell Transplant and Have Iron Overload

Primary Myelofibrosis | Stage I Multiple Myeloma | Stage II Multiple Myeloma | Stage III Multiple Myeloma | Iron Overload | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell... and other conditions

United States
Pulmocide Ltd

Terminated

Anti-viral Effect of PC786 on RSV Infection on HSCT Recipients (TreatRSV1)

Respiratory Syncytial Virus Infections

United Kingdom
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Autologous Peripheral Blood Stem Cell Transplant Followed by Donor Bone Marrow Transplant in Treating Patients With High-Risk Hodgkin Lymphoma, Non-Hodgkin Lymphoma, Multiple Myeloma, or Chronic Lymphocytic Leukemia

Waldenstrom Macroglobulinemia | Refractory Plasma Cell Myeloma | Recurrent Adult Hodgkin Lymphoma | Recurrent Adult Non-Hodgkin Lymphoma | Recurrent Small Lymphocytic Lymphoma | Refractory Chronic Lymphocytic Leukemia | Refractory Non-Hodgkin Lymphoma | Recurrent Plasma Cell Myeloma | Plasma Cell Leukemia and other conditions

United States
Chinese PLA General Hospital
Navy General Hospital, Beijing

Completed

Decitabine Based Chemotherapy Followed by Haploidentical Lymphocyte Infusion for Elderly Patients With AML

AML

China
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Fludarabine, Bendamustine, and Rituximab in Treating Participants With Lymphoid Cancers Undergoing Stem Cell Transplant

Follicular Lymphoma | Mantle Cell Lymphoma | Marginal Zone Lymphoma | Chronic Lymphocytic Leukemia | Recurrent Diffuse Large B-Cell Lymphoma | CD20 Positive | T-Cell Non-Hodgkin Lymphoma

United States
Azienda Socio Sanitaria Territoriale degli Spedali...
Janssen Diagnostics, LLC

Completed

CEC Count Changes to Support GvHD Diagnosis. (ALLOCEC)

Endothelial Dysfunction | Graft vs Host Disease | Complications of Organ Transplant Stem Cells

Italy
Peking University
Peking Union Medical College Hospital; Chinese PLA General Hospital; The First... and other collaborators

Completed

Haplo-identical HSCT Versus Chemotherapy for Adult Acute Lymphoblastic Leukemia Patients

Acute Lymphoblastic Leukemia

China
Gazi University

Completed

Physical Deteriorations in Allo-HSCT.

Stem Cell Transplantation

Turkey
Hospices Civils de Lyon

Completed

Three Modalities of Treatment in Operable and Resectable Stage IIIA (T1-3, N2) Non-Small Cell Lung Cancer (NSCLC)

Non-small Cell Lung Cancer

France
Millennium Pharmaceuticals, Inc.

Terminated

A Dose-Finding Study of Vedolizumab for Treatment of Steroid-Refractory Acute Intestinal Graft-Versus-Host Disease (GvHD) in Participants Who Have Undergone Allogeneic Hematopoietic Stem Cell Transplantation (Allo-HSCT)

Allogeneic Hematopoietic Stem Cell Transplantation

United States, Belgium, Sweden, France, Norway

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