Search clinical trials for: Single Nucleotide Polymorphisms

Total 9071 results

Wyeth is now a wholly owned subsidiary of Pfizer
Solvay Pharmaceuticals

Terminated

Study Evaluating the Safety and Tolerability of Single Ascending Dose (SAD) SLV-351 in Healthy Subjects

Healthy
Seoul National University Hospital
Kyowa Hakko Kirin Pharma, Inc.; Jeil-Kirin Pharmaceutical Inc.

Completed

Pharmacokinetic, Pharmacodynamic and Safety Evaluation After Single Oral Administration of KRN1493

Healthy

Korea, Republic of
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Single Ascending Dose Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of HSD-016

Healthy Subjects

United States
Pfizer

Completed

Single-Dose Study Of PF-04603629 In Type 2 Diabetic Subjects

Diabetes Mellitus, Type 2

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating Safety, Tolerability and Pharmacokinetics of Single and Multiple Dose of SAM-531

Alzheimer Disease

France
Seoul National University Hospital

Unknown

Laparoendoscopic Single-site Radical Nephrectomy for Localized Renal Cell Carcinoma (LESS)

Localized Renal Cell Carcinoma

Korea, Republic of
Pfizer

Completed

Single Dose Escalation Study of PF-04360365 In Subjects With Mild To Moderate Alzheimer's Disease

Alzheimer's Disease

United States
Stetrix, Inc.
Baptist Memorial Health Care Corporation

Completed

Prevention and/or Reduction of Hemorrhoids and/or Thrombosed External Hemorrhoids Using the HEM-AVERT Perianal Stabilizer Instrument (HEM-AVERT)

Hemorrhoids

United States
AstraZeneca

Completed

Study to Investigate Safety, Tolerability and PK Following Single and Multiple Ascending Doses of AZD7295 in Japanese

Healthy Subjects

Japan
Pfizer
Medivation, Inc.

Completed

A Phase 1 Trial To Assess The Safety And Pharmacokinetics Of Single, Ascending, Oral Doses Of Dimebon In Healthy Adults

Healthy Volunteers

Belgium
Merck Sharp & Dohme LLC

Completed

Antihypertensive Response to Losartan and Genetic Polymorphisms

Hypertension
BioLineRx, Ltd.

Completed

A Positron Emission Tomography (PET) Study to Assess the Degree of Dopamine-2 (D2) Receptor Occupancy in the Human Brain After Single Doses of BL-1020 or Perphenazine in Healthy Male Subjects Using [11C]Raclopride as PET Tracer

Healthy

Sweden
RTI International
National Institute on Drug Abuse (NIDA)

Completed

Safety, Tolerability, and Pharmacokinetics of Single, Escalating Oral Doses of RTI-336 in Healthy, Male Subjects

Cocaine Dependence

United States
Pfizer

Completed

A Single Dose Study Of PF-04620110 In Overweight And Obese, Otherwise Healthy Volunteers

Overweight

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating Single Doses of BLI-489 in Healthy Subjects

Healthy Subjects

United States
Eli Lilly and Company

Completed

A Safety Study of LY2811376 Single Doses in Healthy Subjects

Alzheimer's Disease

United States
Bavarian Nordic
National Institutes of Health (NIH)

Completed

Single-Blind, Controlled Safety and Immunogenicity Study of Recombinant MVA Virus to Treat HIV Infection

HIV Infections

Germany
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study to Determine the Impact of Multiple Doses of Ketoconazole on Single-Dose Pharmacokinetics of HCV-796

Healthy
AstraZeneca

Completed

Asthma Control-A "Patient Follow up Programme" Maintenance and Reliever Therapy in a Single Inhaler

Asthma

Vietnam
Sarepta Therapeutics, Inc.

Completed

Pharmacokinetic Study in Cerebral Spinal Fluid After a Single Dose of AVI-4020

West Nile Virus

United States
Sarepta Therapeutics, Inc.

Completed

Pharmacokinetic Study of a Single Dose of AVI-4126 (RESTEN-NG®) in Cerebral Spinal Fluid

Neoplasms

United States
Sarepta Therapeutics, Inc.

Completed

Pharmacokinetic Study of a Single Dose of AVI-4065 in Cerebral Spinal Fluid

Encephalitis

United States
Pfizer

Completed

A Study To Evaluate Whether Food Affects The Plasma Drug Levels Of A 35 mg Single Dose Of PF-04447943 Taken Orally In Healthy Adult Participants

Healthy

United States
AstraZeneca

Completed

Study to Investigate Safety and Tolerability Single Ascending Doses of AZD4017.

Healthy

Japan
AstraZeneca

Completed

To Study Safety, Tolerability and Pharmacokinetics of AZD1305 in Healthy Male Japanese Subjects

Healthy

Japan
Pfizer

Completed

A Study To Investigate The Safety And Efficacy Properties Of PF-00547659 In Patients With Active Ulcerative Colitis

Colitis, Ulcerative

Spain, Belgium, Germany, Czech Republic, Norway, Denmark, Slovakia
Azienda Ospedaliera Ordine Mauriziano di Torino

Unknown

Efficacy Study of Single Agent Trastuzumab or Lapatinib to Treat HER2-Overexpressing Breast Cancer (HERLAP)

Metastatic Breast Cancer

Italy
Shantha Biotechnics Limited

Completed

Phase IV Interchangeability Study of a Liquid Pentavalent Combination Vaccine

Hepatitis B | Pertussis | Tetanus | Diphtheria | Haemophilus Influenzae Type B

India
Mepha Ltd.
SocraTec R&D GmbH; SocraMetrics GmbH

Completed

Esomeprazole Bioavailability Study With 40 mg Oral Single Dose Fasted and Fed Administration

Healthy

Germany
International Biomedical Systems S.p.A.
CSC Pharmaceuticals

Unknown

Numen Stent Assessment Using OCT Technique in a Single Center Study (NAUTIC)

Hyperplasia | Restenosis

Austria
GlaxoSmithKline

Completed

Allergen Challenge Chamber Study With Single Dose Intranasal GSK1004723 Compared With Placebo

Allergic Rhinitis

Germany
Tri-Service General Hospital

Completed

A Single-Dose Pharmacokinetics Study of Tapimycin Injection

Healthy
AstraZeneca

Completed

Study to Investigate Safety and Tolerability Single Ascending Doses of AZD4017

Healthy

Sweden
Deep Breeze

Completed

Vibration Response Imaging (VRI) in Patients That Are Undergoing Pulmonary Interventional Procedure

Central Airway Stenosis

United States, France, Germany, Japan
Seoul National Hospital

Unknown

Association of Multiple Genetic Polymorphisms With Clozapine-Associated Metabolic Change in Schizophrenia

Schizophrenia | Metabolic Syndrome | Genetic Polymorphism

Korea, Republic of
Biogen

Completed

Patient Satisfaction Study of Single-Use Autoinjector for the Delivery of Pre-Filled Avonex Syringe

Multiple Sclerosis
Biogen

Terminated

Phase 1, Dose-Escalation Study of Oral CNF2024(BIIB021) in CLL

B-Cell Chronic Lymphocytic Leukemia

United States
Sanofi

Terminated

To Determine the Objective Response Rate of 4 Cycles of Docetaxel + Anthracycline (Epirubicin or Doxorubicine) Followed by 4 Cycles of Docetaxel Single Agent

Breast Neoplasms

Poland, Austria
Pfizer

Completed

A Study To Evaluate The Safety, Tolerability And Pharmacokinetics Of Single Oral Doses Of PF-03716539 In Healthy Adult Subjects

Healthy Volunteers

Belgium
AstraZeneca

Completed

Phase I Study to Assess Absorption, Metabolism & Excretion of a Single Oral Dose [14C]AZD0530 in Healthy Male Volunteers

Healthy

United Kingdom
University Hospital, Geneva

Unknown

Single Port Access (SPA) Cholecystectomy Versus Standard Laparoscopic Cholecystectomy

Cholecystitis | Symptomatic Gallbladder Stones | Biliary Pancreatitis

Switzerland
National Institute of Arthritis and Musculoskeletal...

Unknown

The Effects of Exercise Versus Inactivity on People With Mitochondrial Muscle Disease

Mitochondrial Myopathy

United States
GlaxoSmithKline

Completed

Use Of SB-705498 In The Acute Treatment Of Migraine

Migraine, Acute

Australia, Netherlands, United Kingdom, Canada
AstraZeneca

Completed

Study to Assess Safety, Tolerability and Pharmacokinetics After Single Doses of AZD1446 to Healthy Volunteers (SAD)

Healthy

Sweden
Sanofi

Terminated

Dose Escalation Safety and Pharmacokinetic Study of AVE9633 as Single Agent in Relapsed/Refractory CD33-Positive Acute Myeloid Leukemia

Myeloid Leukemia

United States, France, Spain
Norgine

Completed

Effect of Single Doses of 10 mg NRL001 Applied as a Suppository to the Anal Canal or Rectum

Fecal Incontinence

United Kingdom
AstraZeneca

Completed

Assess Safety, Tolerability and PK of AZD3199 in Japanese

Healthy

United Kingdom
Javelin Pharmaceuticals

Completed

Open-Label, Single-Dose Study to Evaluate the Safety and PK of DIC075V in Subjects With Renal Insufficiency and Hepatic Impairment Compared to Healthy Subjects and Evaluate the Safety and Pharmacokinetics of HPβCD When Administered in DIC075V Compared to Sporanox® in Healthy Subjects

Hepatic Insufficiency | Healthy | Renal Insufficiency, Chronic

United States, United Kingdom
AstraZeneca

Completed

Study to Investigate the Safety, Tolerability and Pharmacokinetics of Single Doses of AZD8566.

Healthy Volunteer

United Kingdom
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating the Safety and Pharmacokinetics of Ascending Single IV Doses of ERB-257

Healthy Subjects

United States

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