Search clinical trials for: 0.9% NaCl

Total 5306 results

Alnylam Pharmaceuticals

Completed

A Phase 1, Single- and Multi-Dose, Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Subcutaneously Administered ALN-TTRSC (Revusiran) in Healthy Volunteers

TTR-mediated Amyloidosis

United Kingdom
University of Iowa

Completed

Essential Fatty Acids for Major Depression

Major Depression

United States
MassBiologics
Celerion

Completed

First Clinical Study of the Safety and Blood Levels of a Human Monoclonal Antibody (2217LS) Against Lyme Disease Bacteria in Healthy People

Lyme Disease

United States
Ionis Pharmaceuticals, Inc.
Akcea Therapeutics

Completed

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of IONIS APO(a)-LRx in Healthy Volunteers With Elevated Lipoprotein(a)

Elevated Lipoprotein(a)

Canada
Alnylam Pharmaceuticals

Active, not recruiting

HELIOS-B: A Study to Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

Transthyretin Amyloidosis (ATTR) With Cardiomyopathy

United States, Poland, Argentina, Australia, Belgium, France, Germany, Japan, Netherlands, Portugal, Spain, Sweden, United Kingdom, Canada, Czechia, Denmark, Hungary, Ireland, Norway, Korea, Republic of, Austria, Croatia, Israel, Latvia, Lithuan... and more
Universitas Bali Internasional

Completed

The Effects of Intra-articular Platelet-Rich Plasma Injection on The Severity of Knee Osteoarthritis

Osteoarthritis, Knee

Indonesia
Assistance Publique - Hôpitaux de Paris

Completed

Cell Therapy Using Umbilical Cord-derived Mesenchymal Stromal Cells in SARS-CoV-2-related ARDS (STROMA-CoV2)

Severe Acute Respiratory Syndrome Coronavirus 2 | Severe Acute Respiratory Distress Syndrome

France
Arrowhead Pharmaceuticals

Completed

Study of ARO-HSD in Healthy Volunteers and Patients With Non-Alcoholic Steatohepatitis (NASH) or Suspected NASH

Non-alcoholic Steatohepatitis

New Zealand
Dicerna Pharmaceuticals, Inc.

Completed

Study to Evaluate Safety, Tolerability, PK and PD of DCR-PHXC in PH Type 3 Patients (PHYOX4)

Primary Hyperoxaluria Type 3

United States, Germany, Netherlands, United Kingdom
Arrowhead Pharmaceuticals

Completed

Study of ARO-HBV in Normal Adult Volunteers and Patients With Hepatitis B Virus (HBV)

Hepatitis B

Australia, Hong Kong, New Zealand
Berlin Cures GmbH

Completed

A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Efficacy of BC 007 in Healthy Subjects

Healthy Volunteers

Germany
Alnylam Pharmaceuticals

Completed

A Study of the Safety, Tolerability and Pharmacokinetics of ALN-TTR02 in Japanese Healthy Volunteers

Transthyretin (TTR)-Mediated Amyloidosis

United Kingdom
Ahmed Mohamed ELbadawy

Unknown

Prophylaxis Versus Treatment for TURP Syndrome.

Transurethral Resection of Prostate Syndrome

Egypt
Rigshospitalet, Denmark

Completed

Acute Exercise and NK Cell Regulation in Tissue and Circulation After IL-6R Blockade

Appetitive Behavior | Physical Stress | Interleukin-6 Inhibition

Denmark
University of Liege

Completed

G-CSF in the Treatment of Toxic Epidermal Necrolysis (NeupoNET)

Stevens - Johnson Syndrome

Belgium
University Hospital, Basel, Switzerland
Swiss National Science Foundation

Completed

PROVOCATION Trial - PROphylactic intraVenOus Hydration for Contrast Agent Toxicity PreventION

Kidney Failure, Acute

Switzerland, Italy
PhaseBio Pharmaceuticals Inc.

Completed

Phase 1/2a, Randomized, Double-Blind, Placebo-Controlled, Study to Assess Safety, Tolerability, PK and PD Response of PB1023 Injection Following Single and Multiple SQ Doses in Adults With Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

United States
Assistance Publique - Hôpitaux de Paris

Completed

Ilomedin in Septic Shock With Persistent Microperfusion Defects (I-MICRO) (I-MICRO)

Septic Shock Hyperdynamic

France
Rawalpindi Medical College

Completed

Effect of Hot Saline Irrigation on the Operative Field During Endoscopic Sinus Surgery

Rhinosinusitis

Pakistan
MassBiologics

Completed

Evaluate the Safety Pharmacokinetics of a Human Monoclonal Antibody S315 Against Diphtheria Toxin in Healthy Subjects (S315)

Diphtheria

United States
Medical University of Vienna

Completed

Changes in Adaptive Immune Responses and Effector Cell Responses Upon Nasal Allergen Exposure - a Pilot Study

Allergic Rhinitis | Allergic Inflammation

Austria
The Hospital for Sick Children

Completed

0.9% NaCl/Dextrose 5% vs 0.45% NaCl/Dextrose 5% as Maintenance Intravenous Fluids in Hospitalized Children

Hyponatremia

Canada
Chulalongkorn University
National Research Council of Thailand

Terminated

Randomized Controlled Study of the Effectiveness of IV Fluid Infusion in Patients With Acute Ischemic Stroke (IVIS) (IVIS)

Ischemic Stroke

Thailand
Fresenius Kabi

Completed

Effects of Voluven on Hemodynamics and Tolerability of Enteral Nutrition in Patients With Severe Sepsis (CRYSTMAS)

Sepsis

France, Germany
Ankara City Hospital Bilkent

Not yet recruiting

Investigation of the Analgesic Effects of Intradermal and Subdermal Sterile Water Injection on Active Labor Pain

Labor Pain and to Reduce Pain
Noveome Biotherapeutics, formerly Stemnion

Completed

Evaluation of the Effectiveness of ST266 Ophthalmic Drops Compared to Placebo to Treat Allergic Conjunctivitis

Allergic Conjunctivitis

United States
Larissa University Hospital

Completed

Effect of Nasopharyngeal Wash With Normal Saline on SARS-CoV2 Viral Load

SARS-CoV2 Infection

Greece
MiMedx Group, Inc.

Completed

Micronized dHACM Injectable for the Treatment of Plantar Fasciitis (dHACM)

Fasciitis, Plantar

United States
Profil Institut für Stoffwechselforschung GmbH

Completed

A Trial Investigating the Influence of Injection Speed and Volume on the Perception of Subcutaneous Injection Pain

Diabetes Mellitus

Germany
Medical University Innsbruck

Completed

Continuous Wound Infiltration After Hallux Valgus Surgery (CWI-HVS)

Hallux Valgus

Austria
Pierre Van Damme

Completed

A Study to Assess the Acceptability and Usability of a New Device for Intradermal Vaccination

Pain | Vaccination Adverse Event

Belgium
Antonio Fojo
Ipsen

Recruiting

LAnreotide in Metastatic Pheochromocytoma / PARAganglioma (LAMPARA) (LAMPARA)

Pheochromocytoma | Paraganglioma

United States
Centre Hospitalier Universitaire, Amiens

Completed

Hepatic Blood Flow Changes During Fluid Challenge Assessed by MRI in Volunteers Subjects. (PORTEAU)

Hepatic Flow Changes

France
Federal University of Uberlandia

Unknown

Hemodynamic Measurements at Different Inclinations of the Head (HMDIH)

Hypovolemic Shock

Brazil
University of Arkansas, Fayetteville
Danone Research

Completed

The Effect of Vasopressin on Glucose Regulation (HYPERGlu)

Insulin Resistance

United States
Kati Järvelä
Finnish Cultural Foundation

Completed

Effects of Hypertonic Saline-HES Solution on Extracellular Water in Cardiac Surgery Patients

Fluid Volume Disorder

Finland
University Hospital, Basel, Switzerland

Recruiting

Canakinumab for the Treatment of Postprandial Hypoglycemia (CanpHy)

Postprandial Hypoglycemia

Switzerland
Arrowhead Pharmaceuticals

Completed

Study of ARO-AAT in Normal Adult Volunteers

Alpha 1-Antitrypsin Deficiency

New Zealand
Alnylam Pharmaceuticals

Terminated

A Study of an Investigational Drug, ALN-AAT, in Healthy Adult Subjects and Patients With ZZ Type Alpha-1 Antitrypsin Deficiency Liver Disease

Antitrypsin Deficiency Liver Disease

United Kingdom
Albina Nowak, MD

Unknown

Effect of Iron on Cerebral Dopamine Receptor Density in Non-anaemic Premenopausal Women With Low Ferritin and Fatigue

Fatigue | Iron-deficiency

Switzerland
University Hospital, Basel, Switzerland

Completed

Effects of Interleukin-1 Beta on Low Testosterone Levels in Men With Obesity and Metabolic Syndrome (TestIL)

Obesity | Hypogonadism | Metabolic Syndrome X

Switzerland
St. Antonius Hospital

Unknown

Pilot Study on the Pharmacodynamics of Sugammadex in Morbidly Obese Patients: Reversal of Deep Neuromuscular Blockade (MOS)

Neuromuscular Blockade

Netherlands
Erasme University Hospital

Recruiting

Can Peripheral NIRS Predict the Response to a Fluid Challenge in Pediatric Patients: An Interventional Study

Anesthesia

Belgium
Kasr El Aini Hospital

Unknown

Use of Two Modern Hydroxyethyl Starch Solutions in Major Urological Procedures

Urologic Surgical Procedures

Egypt
Prof. Dr. Jörg Leuppi

Terminated

Inhaled Aviptadil for the Treatment of COVID-19 in Patients at High Risk for ARDS

Covid19 | Corona Virus Infection | ARDS | Aviptadil

Switzerland
Human Stem Cell Institute, Russia
Betuvax LLC; CEG BIO LLC

Active, not recruiting

Safety, Tolerability and Immunogenicity of Recombinant COVID-19 Vaccine Betuvax-CoV-2 (Betuvax-CoV2)

COVID-19

Russian Federation
Revimmune
Washington University School of Medicine; Vanderbilt University School of Medicine

Completed

A Study of IL-7 to Restore Absolute Lymphocyte Counts in Sepsis Patients (IRIS-7-B)

Severe Sepsis With Septic Shock

United States
Hospital General de Niños Pedro de Elizalde

Completed

Variation in Natremia Using Two Different Maintenance Intravenous Fluids in Postsurgical Hospitalized Children (surgical-Na)

Hyponatremia

Argentina
Sanofi Pasteur, a Sanofi Company

Completed

Study of a Booster Dose of a Tetravalent Dengue Vaccine in Subjects Who Previously Completed the 3-dose Schedule

Dengue Fever | Dengue Hemorrhagic Fever

Brazil, Colombia, Honduras, Mexico, Puerto Rico
University of Erlangen-Nürnberg Medical School

Completed

Trial to Investigate the Influence of the Homeopathic Remedy Naja-comp on Stroke Therapy in Geriatric Rehabilitation (naja-comp)

Stroke

Germany

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