Search clinical trials for: Nemolizumab

Total 245 results

GlaxoSmithKline

Completed

Efficacy and Safety Study of Mepolizumab Adjunctive Therapy in Subjects With Severe Uncontrolled Refractory Asthma

Asthma

United States, Argentina, Australia, Canada, France, Germany, Japan, Russian Federation, Spain, Ukraine, Belgium, Chile, Korea, Republic of, Mexico, Italy, United Kingdom
Takeda

Completed

Vedolizumab Intravenous (IV) Dose Optimization in Ulcerative Colitis (ENTERPRET)

Colitis, Ulcerative

United States, Canada
Takeda

Completed

Phase III Study of MLN0002 (300 mg) in the Treatment of Ulcerative Colitis

Ulcerative Colitis

Japan
St. Paul's Sinus Centre

Not yet recruiting

th2 Modulation CRSwNP

Chronic Rhinosinusitis With Nasal Polyps

Canada
Policlinico Universitario, Catania

Recruiting

Mepolizumab Effectiveness in Severe Eosinophilic Asthma and Bronchiectasis

Bronchiectasis | Bronchial Asthma

Italy
GlaxoSmithKline

Recruiting

Study in Pediatrics With HypEREosinophilic Syndrome (SPHERE) (SPHERE)

Hypereosinophilic Syndrome

United States, Argentina, Spain, Turkey, Israel, Brazil, Mexico, United Kingdom
GlaxoSmithKline

Completed

Intravenous Mepolizumab In Subjects With Hypereosinophilic Syndromes (HES)

Hypereosinophilic Syndrome | Hypereosinophilia

United States, Belgium, Canada, Germany, Italy, France, Switzerland, Australia
GlaxoSmithKline

Completed

Pharmacokinetics and Pharmacodynamics of Mepolizumab Administered Subcutaneously in Children

Asthma

Japan, United States, United Kingdom, Poland
GlaxoSmithKline

Completed

Intravenous Mepolizumab In Children With Eosinophilic Esophagitis

Oesophagitis, Eosinophilic

United States, Canada, United Kingdom, Australia
GlaxoSmithKline

Terminated

Open-Label Extension Of Intravenous Mepolizumab In Patients With Hypereosinophilic Syndrome

Hypereosinophilic Syndrome

United States, Belgium, Canada, Germany, Italy, France, Australia
University Hospital Schleswig-Holstein
GlaxoSmithKline

Completed

Safety and Efficacy Study of Mepolizumab in Churg Strauss Syndrome (MEPOCHUSS)

Churg Strauss Syndrome

Germany
Takeda

Not yet recruiting

A Study of Vedolizumab in Children and Teenagers With Ulcerative Colitis or Crohn's Disease

Crohn's Disease | Ulcerative Colitis
Bio-Thera Solutions

Completed

Evaluate the Pharmacokinetics of BAT2606 Injection in Healthy Chinese Male Subjects

Severe Asthma

China
GlaxoSmithKline

Not yet recruiting

REIMAGINE - Real World EvaluatIon of Mepolizumab in Severe Asthma achievinG on Treatment clinIcal remissioN, a prospEctive Study (REIMAGINE)

Asthma
University of Crete

Recruiting

Role of Epithelial Barrier Integrity in Biologic Treatment Response of Severe Asthmatics With/Out Chronic Rhinosinusitis With Nasal Polyps (CRSwNP).

Severe Eosinophilic Asthma w/wo CRSwNP

Greece
Temple University
GlaxoSmithKline

Not yet recruiting

Immunological Basis for Mepolizumab Activity in COPD

COPD
Hospital Clinico Universitario de Santiago
GlaxoSmithKline

Recruiting

Effect of Mepolizumab on Severe Eosinophilic Asthma (EMESEA)

Asthma | Eosinophilic Asthma

Spain
Geert D'Haens
Takeda

Completed

An Open Label Phase 4 Study to Evaluate Efficacy of Early Versus Late Use of Vedolizumab in Ulcerative Colitis (LOVE-UC)

Colitis, Ulcerative

Netherlands, Belgium, Hungary
Takeda

Completed

A Pilot Study to Compare the Pharmacokinetics (PK) of Single Subcutaneous (SC) Injections of Vedolizumab Administered in Prefilled Syringe (PFS) Versus (vs) Prefilled Syringe in Needle Safety Device (PFS+NSD) in Healthy Participants

Healthy Volunteers

United States
Takeda

Completed

A Pilot Study to Compare the Pharmacokinetics (PK) of Single Subcutaneous (SC) Injections of Vedolizumab Administered in Prefilled Syringe (PFS) Versus (vs) Prefilled Syringe in Autoinjector (PFS+AI) in Healthy Participants

Healthy Volunteers

United States
Instituto de Investigación Marqués de Valdecilla

Not yet recruiting

Mepolizumab and In-office Nasal Polypectomy in Patients With Chronic Rhinosinusitis (CRS). A Three Arm Study. (MELYSA)

Rhinosinusitis Chronic | Polyp, Nasal

Spain
St. Paul's Sinus Centre

Recruiting

Comparison of Immune Profiles in Chronic Rhinosinusitis Patients After Mepolizumab Treatment

Asthma | Chronic Rhinosinusitis With Nasal Polyps | Chronic Rhinosinusitis Without Nasal Polyps

Canada
Hospices Civils de Lyon
GlaxoSmithKline

Recruiting

Symptoms Control and adhErenCe Assessment During Treatment With MepolizUmab New pREfilled Devices (SECURE)

Asthma

France
Takeda

Recruiting

A Study of Vedolizumab in Children and Teenagers With Moderate to Severe Crohn's Disease (CD)

Crohn's Disease (CD)

United States, Australia, Israel, Belgium, Hungary, Canada, China, Croatia, Czechia, Greece, Italy, Japan, Korea, Republic of, Poland, United Kingdom, Lithuania, Slovakia, Spain
Takeda

Recruiting

Efficacy and Safety of Vedolizumab IV in Chinese Participants With Ulcerative Colitis

Moderately to Severely Active Ulcerative Colitis

China
Takeda

Completed

Phase III Study of MLN0002 (300 mg) in Treatment of Crohn's Disease

Crohn's Disease

Japan
Takeda

Completed

Efficacy and Safety of Vedolizumab Subcutaneously (SC) as Maintenance Therapy in Ulcerative Colitis

Colitis, Ulcerative

United States, Korea, Republic of, Netherlands, Australia, Denmark, Russian Federation, Spain, Croatia, Israel, Serbia, Bulgaria, Canada, Italy, Poland, Ukraine, Hungary, Belgium, Czechia, Turkey, Germany, Japan, Estonia, Mexico, Romania and more
Brigham and Women's Hospital
GlaxoSmithKline

Completed

Mepolizumab As a Steroid-sparing Treatment Option in the Churg Strauss Syndrome (MATOCSS)

Churg Strauss Syndrome

United States
Millennium Pharmaceuticals, Inc.

Completed

Long Term Safety of Vedolizumab (MLN0002) in Patients With Ulcerative Colitis and Crohn's Disease

Crohn's Disease | Ulcerative Colitis

Canada
University of Wisconsin, Madison

Completed

Eosinophilic Airway Inflammation and Mepolizumab

Asthma

United States
Washington University School of Medicine

Active, not recruiting

Defining Predictors of RT Response to Vedolizumab in IBD

Crohn Disease of Small Intestine

United States
Millennium Pharmaceuticals, Inc.

Completed

Study of Vedolizumab (MLN0002) in Patients With Moderate to Severe Crohn's Disease (GEMINI II)

Crohn's Disease

United States, Canada, Puerto Rico
University Medical Center Groningen

Completed

Using Vedolizumab-800CW to Gain Insight Into Local Drug Distribution and Mucosal Target Cells in IBD Patients (VISION)

Crohn Disease | Colitis, Ulcerative

Netherlands
GlaxoSmithKline

Terminated

Efficacy and Safety Study of Mepolizumab in Subjects With Moderate to Severe Atopic Dermatitis

Dermatitis, Atopic

United States, Canada
Takeda

Recruiting

A Study of Vedolizumab in Children With Ulcerative Colitis (UC) or Crohn's Disease (CD)

Crohn's Disease | Ulcerative Colitis

Belgium, Australia, Israel, United States, Hungary, Korea, Republic of, China, Canada, Croatia, Italy, Poland, Slovakia, United Kingdom, Japan, Greece
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield

Recruiting

A Pilot Study of the Use of 129Xe and 1H MRI to Measure the Modulation of Eosinophil-Related Inflammation by Mepolizumab In COPD (SUMMER)

COPD

United Kingdom
Medical Centre Leeuwarden
GlaxoSmithKline

Completed

Use of Nucala in Severe Asthma (UNISA)

Asthma Severe Persistent Uncontrolled

Netherlands
Takeda

Not yet recruiting

A Long-Term Extension Study of Vedolizumab in Children and Teenagers With Ulcerative Colitis (UC) or Crohn's Disease (CD)

Crohn's Disease | Ulcerative Colitis
Takeda

Completed

A Study to Compare the Pharmacokinetics (PK) of Single Subcutaneous (SC) Injections of Vedolizumab Administered in Prefilled Syringe (PFS) Versus (vs) Prefilled Syringe in Autoinjector (PFS+AI) in Healthy Participants

Healthy Volunteers

United States
GlaxoSmithKline

Completed

Mepolizumab in Nasal Polyposis

Nasal Polyps

Netherlands, Belgium, United Kingdom
GlaxoSmithKline

Completed

A Study to Determine Long-term Safety of Mepolizumab in Asthmatic Subjects

Asthma

United States, Argentina, Australia, Canada, France, Germany, Japan, Netherlands, Poland, Russian Federation, Spain, Ukraine, Belgium, Chile, Korea, Republic of, United Kingdom, Czechia, Mexico, Italy
GlaxoSmithKline

Completed

Dose Ranging Pharmacokinetics and Pharmacodynamics Study With Mepolizumab in Asthma Patients With Elevated Eosinophils

Asthma

Germany, France, Estonia, United States
Takeda

Recruiting

Specified Drug-Use Survey on Vedolizumab for IV Infusion 300 mg [Crohn's Disease]

Crohn's Disease

Japan
Hospitales Universitarios Virgen del Rocío
Fundación Pública Andaluza para la gestión de la Investigación en Sevilla

Unknown

Vedolizumab Treatment in HIV-Infected Subjects Without Previous Antiretroviral Therapy

HIV Infections

Spain
Takeda

Completed

Vedolizumab Intravenous (IV) Compared to Placebo in Chinese Participants With Crohn's Disease.

Crohn's Disease

China
National Institute of Allergy and Infectious Diseases...
GlaxoSmithKline; Rho Federal Systems Division, Inc.; Inner-City Asthma Consortium

Completed

A Trial of Mepolizumab Adjunctive Therapy for the Prevention of Asthma Exacerbations in Urban Children (MUPPITS-2)

Asthma

United States
National and Kapodistrian University of Athens

Recruiting

Mepolizumab Effectiveness in Patients With Chronic Rhinosinusitis, Nasal Polyps and Comorbid Severe Eosinophilic Asthma (MepoRiNaPAs)

Chronic Rhinosinusitis With Nasal Polyps | Chronic Rhinosinusitis Without Nasal Polyps | Severe Eosinophilic Asthma

Greece
Rigshospitalet, Denmark

Recruiting

A Randomized, Real-world Head-to-head Study of Dupilumab Versus Mepolizumab in Danish CRSwNP Patients (TORNADO)

Eosinophilia | Chronic Rhinosinusitis With Nasal Polyps | Asthma; Eosinophilic

Denmark
Ottawa Hospital Research Institute
CHEO Research Institute; Nebraska Centre for Substance Abuse Research

Recruiting

Vedolizumab Treatment in Antiretroviral Drug Treated Chronic HIV Infection (HAVARTI)

HIV-infection/AIDS

Canada
Millennium Pharmaceuticals, Inc.

Completed

Study of Vedolizumab in Patients With Moderate to Severe Crohn's Disease (GEMINI III)

Crohn's Disease

United States, Canada

Search clinical trials for: Nemolizumab

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