Clinical Trials Sponsored by Aastrom Biosciences

Total 1938 results

Catalyst Biosciences

Terminated

Study of Coagulation Factor VIIa Marzeptacog Alfa (Activated) in Subjects With Hemophilia A or B

Hemophilia A With Inhibitor | Hemophilia B With Inhibitor

United States, United Kingdom, Taiwan, Italy, Spain, India, Turkey, Malaysia, Russian Federation, Armenia, Georgia, Hungary, Mexico, Poland, South Africa, Ukraine
Palladio Biosciences

No longer available

Lixivaptan in a Single Subject With Intractable Pain Due to Polycystic Kidney Disease

Polycystic Kidney

United States
Kaleido Biosciences

Completed

A Clinical Study to Assess the Physiologic Effects of KB109 in Patients With COVID-19 on Gut Microbiota Structure and Function

Mild-to-Moderate COVID-19

United States
Novadip Biosciences

Completed

Safety and Preliminary Effectiveness of NVD-001 for the Treatment of Low Grade Degenerative Lumbar Spondylolisthesis (Spine1)

Spondylolisthesis

Czechia, Poland, Belgium
Kaleido Biosciences

Completed

A Clinical Study to Assess the Natural History of COVID-19 and Effects of KB109 and Supportive Self-care in Outpatients With Mild-to-moderate COVID-19

Mild-to-moderate COVID-19

United States
Assembly Biosciences

Completed

A Study to Assess Safety, Tolerability, and Pharmacokinetics of ABI-H3733 in Healthy Adults

Chronic Hepatitis B

New Zealand
Assembly Biosciences

Completed

A Study of ABI-H2158 in Healthy Volunteers and Patients With Chronic Hepatitis B

Chronic Hepatitis B

Korea, Republic of, Australia, United States, Hong Kong, United Kingdom, China, New Zealand
Kaleido Biosciences

Terminated

VITORA: Clinical Study to Evaluate the Effect of KB109 on the Gut Microbiome in Subjects Whose Gastrointestinal Tracts Are Colonized With Multiple Drug-resistant Organisms (VITORA)

Vancomycin-Resistant Enterococcus, Extended-Spectrum Beta Lactamase-Producing Enterobacteriaceae, or Carbapenem-Resistant Enterobacteriaceae Colonized Subjects

United States
Kaleido Biosciences

Completed

A Clinical Study to Assess the Effect of Increasing Intake Amounts of Two Novel Glycans on the Gut Microbiota of Healthy Subjects

Healthy

United States
Neurocrine Biosciences

Completed

The Potential for Clinical Dependence and Withdrawal Symptoms Associated With Valbenazine

Tardive Dyskinesia (TD)

United States, Puerto Rico
Assembly Biosciences

Completed

A Study to Assess the Relative Bioavailability and Food Effect of ABI-H2158 in Healthy Adults

Chronic Hepatitis B

United States
Antiva Biosciences

Completed

Study of Topical ABI-1968 in Subjects With Precancerous Cervical Lesions From Human Papillomavirus (HPV) Infection

Cervical Cancer | Cervical Intraepithelial Neoplasia | CIN | Human Papilloma Virus | Cervical Dysplasia | HSIL of Cervix | Cervical Neoplasm | HSIL | High-Grade Squamous Intraepithelial Lesions | High-grade Cervical Intraepithelial Neoplasia

United States, Australia
Translational Biosciences

Unknown

Umbilical Cord Tissue-derived Mesenchymal Stem Cells for Rheumatoid Arthritis

Rheumatoid Arthritis

Panama
Neurocrine Biosciences

Completed

A Study of the Pharmacokinetics, Pharmacodynamics, and Safety of Opicapone in Subjects With Parkinson's Disease Taking Levodopa.

Parkinson Disease

United States
Origin Biosciences

Completed

A Natural History Study of Molybdenum Cofactor and Isolated Sulfite Oxidase Deficiencies

Molybdenum Cofactor Deficiency | Isolated Sulfite Oxidase Deficiency

Spain, Israel, United States, United Kingdom, Canada, Netherlands, Germany, Saudi Arabia, Tunisia, Japan, Italy, Malaysia, Poland, Turkey
Origin Biosciences

Completed

Phase 1 Single Dose Study of ALXN1101 in Healthy Volunteers

Molybdenum Cofactor Deficiency (MoCD) | Rare Autosomal Recessive Disorder | Deficiency of Activity of Molybdenum-dependent Enzymes (Sulfite Oxidase [SOX], Xanthine Dehydrogenase, and Aldehyde Oxidase)

United States
Neurocrine Biosciences

Completed

Safety and Tolerability Study of NBI-98854 for the Treatment of Tardive Dyskinesia (Kinect 4)

Tardive Dyskinesia

United States, Canada, Puerto Rico
Translational Biosciences

Unknown

Safety and Feasibility Study of Intranasal Mesenchymal Trophic Factor (MTF) for Treatment of Asthma

Asthma

Panama
Translational Biosciences

Withdrawn

Safety and Feasibility Study of Autologous Stromal Vascular Fraction (SVF) Cells for Treatment of Osteoarthritis

Osteoarthritis

Panama
Translational Biosciences

Withdrawn

Clinical Study of Umbilical Cord Tissue Mesenchymal Stem Cells (UC-MSC) for Treatment of Osteoarthritis

Osteoarthritis of the Knee

Panama
Translational Biosciences

Withdrawn

Autologous Adipose Tissue Stromal Vascular Fraction Cells for Rheumatoid Arthritis

Rheumatoid Arthritis

Panama
Kaleido Biosciences

Completed

Study to Evaluate the Tolerability of Prebiotics on the Microbiota

Healthy

Ireland
Neurocrine Biosciences

Completed

Safety, Pharmacokinetics, and Pharmacodynamics of NBI-98854 in Children and Adolescents With Tourette Syndrome (T-FORCE)

Tourette Syndrome

United States
Neurocrine Biosciences

Withdrawn

Safety, Pharmacokinetics and Pharmacodynamics of NBI-77860 in Adolescent Females With Congenital Adrenal Hyperplasia

Congenital Adrenal Hyperplasia

United States
Knopp Biosciences

Completed

Dexpramipexole and Warfarin Drug Drug Interaction (DDI) Study

Healthy Volunteers

United States
Knopp Biosciences

Completed

Dexpramipexole SAD/MAD Study

Amyotrophic Lateral Sclerosis

United States
Knopp Biosciences

Completed

Study in Healthy Volunteers of the Bioavailability of Dexpramipexole Tablets and Food Effects

Healthy Volunteers

United States
Knopp Biosciences

Completed

Study to Evaluate the QTC Interval in Healthy Volunteers Dosed With Dexpramipexole (QTC = Electrocardiogram (ECG) Interval Measured From the Onset of the QRS Complex to the End of the T Wave Corrected for Heart Rate)

Amyotrophic Lateral Sclerosis

United States
Neurocrine Biosciences

Completed

Efficacy and Safety of NBI-98854 in Subjects With Tardive Dyskinesia

Tardive Dyskinesia

Canada
Strategic Biosciences

Unknown

Comparative Study of Sinol and Sinol-M in Patients With Congestion Due to Allergic Rhinitis (SMAN)

Allergic Rhinitis

United States
YM BioSciences

Terminated

DPPE in Combination With Epirubicin and Cyclophosphamide in the Treatment of Breast Cancer

Breast Cancer | Metastases

United Kingdom
Zomagen Biosciences, Ltd

Completed

A Study to Evaluate VTX2735 in Patients With Cryopyrin-associated Periodic Syndrome (Explore)

Cryopyrin Associated Periodic Syndrome

United States
Brii Biosciences, Inc.

Withdrawn

A Safety and Efficacy Study of Human Monoclonal Antibodies, BRII-196 and BRII-198 for the Treatment of Patients With COVID-19

COVID-19

China
Assembly Biosciences

Not yet recruiting

A Study to Assess the Safety, Pharmacokinetics, and Antiviral Activity of ABI-5366 in Healthy Participants and Participants Seropositive for HSV-2 With Recurrent Genital Herpes

Recurrent Genital Herpes Simplex Type 2

New Zealand
Anwita Biosciences

Recruiting

Phase 1 Study of AWT020 in Advanced Cancer

Advanced Cancer

Australia
Aura Biosciences

Recruiting

A Phase 3 Randomized, Masked, Controlled Trial to Evaluate Efficacy and Safety of Belzupacap Sarotalocan (AU-011) Treatment Compared to Sham Control in Subjects With Primary Indeterminate Lesions or Small Choroidal Melanoma (CoMpass)

Ocular Melanoma | Uveal Melanoma | Choroidal Melanoma | Indeterminate Lesions

United States, Australia, United Kingdom
IDEAYA Biosciences

Recruiting

A Study of PARG Inhibitor IDE161 in Participants With Advanced Solid Tumors

Breast Cancer | Ovarian Cancer | Prostate Cancer | Pancreas Cancer | Advanced or Metastatic Solid Tumors

United States
DEKA Biosciences

Recruiting

Evaluating Safety and Biomarkers Using DK210 (EGFR) for Locally Advanced or Metastatic EGFR+ Tumors

Kidney Cancer | Cancer | Head and Neck Cancer | Gynecologic Cancer | Colorectal Cancer | Solid Tumor | Non Small Cell Lung Cancer | Skin Cancer | Pancreas Cancer

United States
Spruce Biosciences

Recruiting

A Phase 2 Study to Evaluate the Safety, Efficacy and PK of Tildacerfont in Children With CAH

Congenital Adrenal Hyperplasia | 21-OHD

United States
Neurocrine Biosciences

Recruiting

Study to Evaluate NBI-921352 as Adjunctive Therapy in Subjects With SCN8A Developmental and Epileptic Encephalopathy Syndrome (SCN8A-DEE)

SCN8A Developmental and Epileptic Encephalopathy Syndrome

United States
IDEAYA Biosciences

Recruiting

Study of IDE397 in Participants With Solid Tumors Harboring MTAP Deletion

Solid Tumor

United States, Taiwan, Korea, Republic of, France, Spain, Australia, Germany
Persephone Biosciences

Recruiting

ARGONAUT: Stool and Blood Sample Bank for Cancer Patients

Colorectal Cancer | Triple Negative Breast Cancer | Non-small Cell Lung Cancer | Pancreas Cancer

United States
Neurocrine Biosciences

Enrolling by invitation

Extension Study to Evaluate How Safe and Tolerable NBI-921352 is as an Adjunctive Therapy for Participants With SCN8A-DEE

SCN8A Developmental and Epileptic Encephalopathy Syndrome

United States
Neurocrine Biosciences

Active, not recruiting

Global Safety and Efficacy Registration Study of Crinecerfont in Pediatric Patients With Classic Congenital Adrenal Hyperplasia (CAHtalyst Pediatric Study)

Congenital Adrenal Hyperplasia

United States, United Kingdom, France, Greece, Italy, Spain, Belgium, Canada, Germany, Poland
Sanguine Biosciences

Completed

At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions

Depression | Melanoma | Epilepsy | Lymphoma | Multiple Sclerosis | Kidney Cancer | Cervical Cancer | Diabetes Mellitus | Leukemia | Breast Cancer | Chronic Kidney Diseases | Chronic Obstructive Pulmonary Disease | Parkinson's Disease | Systemic Lupus Erythematosus | Multiple Myeloma | Hepatitis B | Insomnia | Colorectal Cancer | HIV/AID... and other conditions

United States
KBP Biosciences

Completed

Safety, Tolerability and Pharmacokinetics of KBP-5074 in Healthy Subjects and Subjects With Renal Impairment

Healthy | Renal Insufficiency

United States
Neurocrine Biosciences

Active, not recruiting

Study to Evaluate the Efficacy, Safety, and Tolerability of Luvadaxistat in Participants With Cognitive Impairment Associated With Schizophrenia (ERUDITE)

Schizophrenia

United States, Spain, Serbia, Czechia, Bulgaria, Mexico
Walden Biosciences

Completed

Single Ascending Dose Study of WAL0921 in Healthy Subjects

Healthy

United States
Persephone Biosciences

Active, not recruiting

My Baby Biome: Infant Stool Samples for Microbiome Health (MBB)

Dysbiosis

United States
Neurocrine Biosciences

Completed

Study to Assess the Efficacy and Safety of NBI-1065845 in Adults With Major Depressive Disorder (MDD) (SAVITRI)

Major Depressive Disorder

United States, Czechia, Bulgaria, Poland, Slovakia, Sweden

Clinical Trials Sponsored by Aastrom Biosciences

Sponsors and Collaborators

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CROs in Luxembourg

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