Clinical Trials Sponsored by Adventa Biosciences

Total 1902 results

Neurocrine Biosciences

Terminated

Study to Evaluate the Efficacy, Safety, and Tolerability of Valbenazine as an Adjunctive Treatment for Schizophrenia

Schizophrenia

United States
Sanguine Biosciences

Withdrawn

Study SBX-01-101: A Stool Collection Study in Colorectal Cancer (CRC) Patients Treated With Irinotecan-Based Regimens

Colorectal Cancer

United States
Spruce Biosciences

Completed

A Study of Safety and Efficacy of Tildacerfont in Females With Polycystic Ovary Syndrome and Elevated Adrenal Androgens

Polycystic Ovary Syndrome

United States
Assembly Biosciences

Completed

A First in Human Study to Assess Safety, Tolerability, Pharmacokinetics of ABI-4334 in Healthy Subjects

Chronic Hepatitis B

New Zealand
Neurocrine Biosciences

Enrolling by invitation

Extension Study to Evaluate NBI-827104 in Pediatric Participants With Epileptic Encephalopathy With Continuous Spike-and-Wave During Sleep (Steamboat 2)

Epileptic Encephalopathy | Continuous Spike and Wave During Sleep

United States, Denmark, Spain, Switzerland, United Kingdom
Bond Biosciences

Terminated

A Study to Evaluate BBI-001 in Hereditary Haemochromatosis (HH) Patients and Iron Deficient Volunteers

Hereditary Hemochromatosis

Australia
Xeno Biosciences

Completed

A Phase 1 Study to Evaluate Safety and Tolerability of Single and Multiple Ascending Doses of XEN-101

Healthy

Hungary
Codiak BioSciences

Terminated

A Study of exoASO-STAT6 (CDK-004) in Patients With Advanced Hepatocellular Carcinoma (HCC) and Patients With Liver Metastases From EIther Primary Gastric Cancer or Colorectal Cancer (CRC)

Advanced Hepatocellular Carcinoma (HCC) | Gastric Cancer Metastatic to Liver | Colorectal Cancer Metastatic to Liver

United States
Asana BioSciences

Terminated

Study of ASN003 in Subjects With Advanced Solid Tumors

Melanoma | Neoplasms | Colorectal Neoplasm | Carcinoma, Non-small Cell Lung

United States
Palladio Biosciences

Completed

The ELiSA Study - Evaluation of Lixivaptan in Subjects With Autosomal Dominant Polycystic Kidney Disease

Autosomal Dominant Polycystic Kidney Disease

United States
Neurocrine Biosciences

Completed

Opicapone Treatment Initiation Open-Label Study (OPTI-ON)

Parkinson Disease

United States
Assembly Biosciences

Terminated

A Study of ABI-H2158-containing Regimens in Participants With Chronic Hepatitis B Virus Infection

Chronic Hepatitis B

China, Korea, Republic of, United States, United Kingdom, Australia, Canada, Hong Kong, Taiwan, New Zealand
LISCure Biosciences

Completed

A Study to Assess the Safety and Tolerability of LB-P6 and LB-P8 in Healthy Participants

Rheumatoid Arthritis | Non-Alcoholic Steatohepatitis

Australia
Neurocrine Biosciences

Completed

Safety, Efficacy, and Tolerability of NBI-827104 for the Treatment of Essential Tremor

Essential Tremor

Netherlands
Neurocrine Biosciences

Terminated

Safety and Efficacy of NBI-98854 in Pediatric Subjects With Tourette Syndrome

Tourette Syndrome

United States, Puerto Rico
Hope Biosciences

Completed

Phase 1/2a Clinical Trial to Assess the Safety of HB-adMSCs for the Treatment of Rheumatoid Arthritis (HB-adMSCs)

Rheumatoid Arthritis

United States
Locus Biosciences

Completed

Safety, Tolerability, and PK of LBP-EC01 in Patients With Lower Urinary Tract Colonization Caused by E. Coli

Urinary Tract Infections

United States
Pyramid Biosciences

Completed

A Study to Assess the Effect of Food on the Absorption and Bioavailability of PBI-200

Food Effect in Healthy Volunteers

United States
Kaleido Biosciences

Terminated

UNLOCKED: A Phase 2, Open-label Trial With KB195 in Subjects With a Urea Cycle Disorder (UNLOCKED)

Urea Cycle Disorder

Belgium, United States, Spain, United Kingdom, Germany, Switzerland, Turkey
Catalyst Biosciences

Terminated

Study of Coagulation Factor VIIa Marzeptacog Alfa (Activated) in Subjects With Hemophilia A or B

Hemophilia A With Inhibitor | Hemophilia B With Inhibitor

United States, United Kingdom, Taiwan, Italy, Spain, India, Turkey, Malaysia, Russian Federation, Armenia, Georgia, Hungary, Mexico, Poland, South Africa, Ukraine
Palladio Biosciences

No longer available

Lixivaptan in a Single Subject With Intractable Pain Due to Polycystic Kidney Disease

Polycystic Kidney

United States
Kaleido Biosciences

Completed

A Clinical Study to Assess the Physiologic Effects of KB109 in Patients With COVID-19 on Gut Microbiota Structure and Function

Mild-to-Moderate COVID-19

United States
Novadip Biosciences

Completed

Safety and Preliminary Effectiveness of NVD-001 for the Treatment of Low Grade Degenerative Lumbar Spondylolisthesis (Spine1)

Spondylolisthesis

Czechia, Poland, Belgium
Kaleido Biosciences

Completed

A Clinical Study to Assess the Natural History of COVID-19 and Effects of KB109 and Supportive Self-care in Outpatients With Mild-to-moderate COVID-19

Mild-to-moderate COVID-19

United States
Assembly Biosciences

Completed

A Study to Assess Safety, Tolerability, and Pharmacokinetics of ABI-H3733 in Healthy Adults

Chronic Hepatitis B

New Zealand
Assembly Biosciences

Completed

A Study of ABI-H2158 in Healthy Volunteers and Patients With Chronic Hepatitis B

Chronic Hepatitis B

Korea, Republic of, Australia, United States, Hong Kong, United Kingdom, China, New Zealand
Kaleido Biosciences

Terminated

VITORA: Clinical Study to Evaluate the Effect of KB109 on the Gut Microbiome in Subjects Whose Gastrointestinal Tracts Are Colonized With Multiple Drug-resistant Organisms (VITORA)

Vancomycin-Resistant Enterococcus, Extended-Spectrum Beta Lactamase-Producing Enterobacteriaceae, or Carbapenem-Resistant Enterobacteriaceae Colonized Subjects

United States
Kaleido Biosciences

Completed

A Clinical Study to Assess the Effect of Increasing Intake Amounts of Two Novel Glycans on the Gut Microbiota of Healthy Subjects

Healthy

United States
Neurocrine Biosciences

Completed

The Potential for Clinical Dependence and Withdrawal Symptoms Associated With Valbenazine

Tardive Dyskinesia (TD)

United States, Puerto Rico
Assembly Biosciences

Completed

A Study to Assess the Relative Bioavailability and Food Effect of ABI-H2158 in Healthy Adults

Chronic Hepatitis B

United States
Antiva Biosciences

Completed

Study of Topical ABI-1968 in Subjects With Precancerous Cervical Lesions From Human Papillomavirus (HPV) Infection

Cervical Cancer | Cervical Intraepithelial Neoplasia | CIN | Human Papilloma Virus | Cervical Dysplasia | HSIL of Cervix | Cervical Neoplasm | HSIL | High-Grade Squamous Intraepithelial Lesions | High-grade Cervical Intraepithelial Neoplasia

United States, Australia
Translational Biosciences

Unknown

Umbilical Cord Tissue-derived Mesenchymal Stem Cells for Rheumatoid Arthritis

Rheumatoid Arthritis

Panama
Neurocrine Biosciences

Completed

A Study of the Pharmacokinetics, Pharmacodynamics, and Safety of Opicapone in Subjects With Parkinson's Disease Taking Levodopa.

Parkinson Disease

United States
Origin Biosciences

Completed

A Natural History Study of Molybdenum Cofactor and Isolated Sulfite Oxidase Deficiencies

Molybdenum Cofactor Deficiency | Isolated Sulfite Oxidase Deficiency

Spain, Israel, United States, United Kingdom, Canada, Netherlands, Germany, Saudi Arabia, Tunisia, Japan, Italy, Malaysia, Poland, Turkey
Origin Biosciences

Completed

Phase 1 Single Dose Study of ALXN1101 in Healthy Volunteers

Molybdenum Cofactor Deficiency (MoCD) | Rare Autosomal Recessive Disorder | Deficiency of Activity of Molybdenum-dependent Enzymes (Sulfite Oxidase [SOX], Xanthine Dehydrogenase, and Aldehyde Oxidase)

United States
Neurocrine Biosciences

Completed

Safety and Tolerability Study of NBI-98854 for the Treatment of Tardive Dyskinesia (Kinect 4)

Tardive Dyskinesia

United States, Canada, Puerto Rico
Translational Biosciences

Unknown

Safety and Feasibility Study of Intranasal Mesenchymal Trophic Factor (MTF) for Treatment of Asthma

Asthma

Panama
Translational Biosciences

Withdrawn

Safety and Feasibility Study of Autologous Stromal Vascular Fraction (SVF) Cells for Treatment of Osteoarthritis

Osteoarthritis

Panama
Translational Biosciences

Withdrawn

Clinical Study of Umbilical Cord Tissue Mesenchymal Stem Cells (UC-MSC) for Treatment of Osteoarthritis

Osteoarthritis of the Knee

Panama
Translational Biosciences

Withdrawn

Autologous Adipose Tissue Stromal Vascular Fraction Cells for Rheumatoid Arthritis

Rheumatoid Arthritis

Panama
Kaleido Biosciences

Completed

Study to Evaluate the Tolerability of Prebiotics on the Microbiota

Healthy

Ireland
Neurocrine Biosciences

Completed

Safety, Pharmacokinetics, and Pharmacodynamics of NBI-98854 in Children and Adolescents With Tourette Syndrome (T-FORCE)

Tourette Syndrome

United States
Neurocrine Biosciences

Withdrawn

Safety, Pharmacokinetics and Pharmacodynamics of NBI-77860 in Adolescent Females With Congenital Adrenal Hyperplasia

Congenital Adrenal Hyperplasia

United States
Knopp Biosciences

Completed

Dexpramipexole and Warfarin Drug Drug Interaction (DDI) Study

Healthy Volunteers

United States
Knopp Biosciences

Completed

Dexpramipexole SAD/MAD Study

Amyotrophic Lateral Sclerosis

United States
Knopp Biosciences

Completed

Study in Healthy Volunteers of the Bioavailability of Dexpramipexole Tablets and Food Effects

Healthy Volunteers

United States
Knopp Biosciences

Completed

Study to Evaluate the QTC Interval in Healthy Volunteers Dosed With Dexpramipexole (QTC = Electrocardiogram (ECG) Interval Measured From the Onset of the QRS Complex to the End of the T Wave Corrected for Heart Rate)

Amyotrophic Lateral Sclerosis

United States
Neurocrine Biosciences

Completed

Efficacy and Safety of NBI-98854 in Subjects With Tardive Dyskinesia

Tardive Dyskinesia

Canada
Strategic Biosciences

Unknown

Comparative Study of Sinol and Sinol-M in Patients With Congestion Due to Allergic Rhinitis (SMAN)

Allergic Rhinitis

United States
YM BioSciences

Terminated

DPPE in Combination With Epirubicin and Cyclophosphamide in the Treatment of Breast Cancer

Breast Cancer | Metastases

United Kingdom

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