Clinical Trials Sponsored by Amicus Therapeutics

Total 7103 results

University of Florida
Amicus Therapeutics

Completed

Diet and Exercise in Pompe Disease

Lysosomal Storage Diseases | Glycogen Storage Disease Type II | Pompe Disease

United States
University of Florida
Amicus Therapeutics

Terminated

A Pilot Study of Zavesca® in Patients With Pompe Disease and Infusion Associated Reaction

Pompe Disease | Hypersensitivity Reaction
Vicus Therapeutics

Terminated

Efficacy and Safety Study of Etodolac and Propranolol in Patients With Clinically Progressive Prostate Cancer

Prostatic Neoplasms

United States
Vicus Therapeutics

Completed

Regimen for the Treatment of Cachexia in Subjects With NSCLC (VT-122)

Cachexia

India, United States
Vicus Therapeutics

Unknown

Study of Sorafenib With or Without VT-122 in Patients With Hepatocellular Carcinoma (HCC)

HCC

United States
Caroline Michaela Kistorp
Rigshospitalet, Denmark; Amicus Therapeutics

Active, not recruiting

Real World Evidence Study of Danish Fabry Patients (RWE-FABRY)

Fabry Disease

Denmark
Scioderm, Inc.
Food and Drug Administration (FDA); Amicus Therapeutics

Terminated

Open-Label Extension Study to Evaluate the Safety of SD-101 Cream in Participants With Epidermolysis Bullosa

Epidermolysis Bullosa

United States
University Hospital, Bordeaux
Amicus Therapeutics; Fédération Française de Cardiologie; Fondation Bordeaux...

Completed

Assessment of the Relations Between Endothelial and Venous Dysfunctions and Left Ventricular Obstruction in Genetic Hypertrophic Cardiomyopathies (HCM-Vein)

Endothelial Dysfunction | Hypertrophic Cardiomyopathy

France
Ospedale San Donato
Amicus Therapeutics; Institute of Biomedicine and Molecular Immunology - CNR

Completed

Effect of Migalastat on Cardiac Involvement in Fabry Disease (MAIORA)

Heart Diseases | Fabry Disease

Italy
General University Hospital, Prague
Charles University, Czech Republic; Amicus Therapeutics; Klinické centrum ISCARE

Unknown

Screening of Fabry Disease in Patients With GI Symptoms (GiFD)

Fabry Disease

Czechia
Ranok Therapeutics (Hangzhou) Co., Ltd.

Recruiting

A Study of RNK05047 in Subjects With Advanced Solid Tumors/Diffuse Large B-cell Lymphoma (CHAMP-1)

Advanced Solid Tumor | DLBCL

United States
Zalicus

Completed

A Study Comparing CRx-102 Plus Disease-modifying Anti-rheumatic Drug (DMARD) Therapy to Placebo Plus DMARD Therapy in RA

Rheumatoid Arthritis
Zalicus

Completed

A Phase II Trial Comparing Z-102 With Placebo In Patients With Moderate To Severe Rheumatoid Arthritis (Synergy)

Rheumatoid Arthritis

United States
Zalicus

Completed

Multicenter Study to Evaluate CRx-102 vs. Each of Its Components to Treat Active Rheumatoid Arthritis (MARS-1)

Rheumatoid Arthritis

United States, Poland, Argentina, Romania, Serbia, Canada, Estonia, Russian Federation, Lithuania, South Africa, Hungary, Mexico
Zalicus

Completed

Phase I Study of Topical CRx-191 in Normal Healthy Volunteers

Healthy

Germany
Zalicus

Terminated

CRx-102 Osteoarthritis Multicenter Evaluation Trial (COMET-1)

Knee Osteoarthritis

United States, Canada
Zalicus

Completed

Efficacy and Safety Study of Z160 in Subjects With Postherpetic Neuralgia (PHN)

Postherpetic Neuralgia

United States
Zalicus

Completed

Phase 2 Efficacy Trial of Z160 in Lumbosacral Radiculopathy

Lumbosacral Radiculopathy

United States
Zalicus

Terminated

Long Term Safety Trial of z102 and Prednisone in Patients With Moderate to Severe Rheumatoid Arthritis

Rheumatoid Arthritis

Serbia
Zalicus

Completed

A Single-Center Exploratory Study to Assess the Activity of CRx-197-002 in Plaque Psoriasis (197-002)

Plaque Psoriasis

Germany
Zalicus

Completed

Study of CRx-401 on Glucose Levels in Subjects With Type II Diabetes

Type 2 Diabetes

Canada
Zalicus

Completed

A Phase I Study to Assess the Safety and Tolerability of Topical CRx-197 Formulations in Healthy Volunteers

Atopic Dermatitis

Germany
Akebia Therapeutics
Cyclerion Therapeutics

Completed

A Study to Evaluate the Soluble Guanylate Cyclase (sGC) Stimulator IW-1973 in Diabetic Nephropathy / Diabetic Kidney Disease as Measured by Albuminuria

Type 2 Diabetes Mellitus With Diabetic Nephropathy

United States
Akebia Therapeutics
Cyclerion Therapeutics

Completed

A Study of the Effect of IW-1973 on the Exercise Capacity of Patients With Heart Failure With Preserved Ejection Fraction (HFpEF) (CAPACITY-HFpEF)

Heart Failure With Preserved Ejection Fraction

United States, Canada
Marcus Migura
Mercy Health

Completed

A Transparent Elasticized Adhesive Occlusive Compression Bandage for Use as an Arterial Tourniquet

Hemorrhage | Vascular Injury

United States
Eikon Therapeutics
Impact Therapeutics, Inc.

Recruiting

A First-in-human Study of PARP1 Selective Inhibitor, IMP1734, in Participants With Advanced Solid Tumors

Advanced Solid Tumor

Australia, United States
CRISPR Therapeutics AG

Active, not recruiting

A Safety and Efficacy Study Evaluating CTX130 in Subjects With Relapsed or Refractory Renal Cell Carcinoma (COBALT-RCC)

Renal Cell Carcinoma

United States, Australia, Canada, Netherlands
APRINOIA Therapeutics, LLC

Active, not recruiting

A First-in-Human Study to Assess Single Doses of APNmAb005 in Healthy Participants

Alzheimer Disease | Tauopathies | Healthy Volunteers

United States
Azidus Brasil

Suspended

Efficacy and Safety of Hydroxychloroquine and Azithromycin for the Treatment of Ambulatory Patients With Mild COVID-19

Covid-19

Brazil
Azidus Brasil

Suspended

Non-inferiority Clinic of Kollagenase® Compared Iruxol® in Treatment of Cutaneous Ulcers

Ulcers

Brazil
Azidus Brasil

Suspended

Pharmacodynamics Of Product Octreotide Acetate Lar 30 Mg Compared To Product Sandostatin LAR ®

Acromegaly

Brazil
Azidus Brasil

Withdrawn

Efficacy and Safety of the Association Drugs in Patients With Allergic Dermatitis

Dermatitis

Brazil
Azidus Brasil

Withdrawn

Sodic Heparin Effectiveness of the Treatment of Burns (Heparin)

Burns

Brazil
Azidus Brasil

Withdrawn

Clinical Trial Of The Effectiveness Of The Product Cloratadd D (Loratadine + Pseudoephedrine Sulfate) Produced By The Laboratory EMS S/A, Compared To The Drug Claritin D Produced By Schering-Plough S/A, In Patients With Allergic Rhinitis

Allergic Rhinitis

Brazil
Azidus Brasil

Withdrawn

Efficacy of Sodium Heparin in Prophylaxis of Venous Thromboembolism in Surgical Patients

Venous Thromboembolism
Azidus Brasil

Completed

Efficacy of the Combination Bismuth + Neomycin + Procaine in the Treatment of Recurrent Aphthous Ulceration

Aphtous Ulcers

Brazil
Azidus Brasil

Completed

Efficacy and Safety of Sodium Heparin

Cardiac Surgery

Brazil
Azidus Brasil

Completed

Pharmacokinetics and Pharmacodynamics of the Interferon Beta-1a Produced by Laboratorio Quimico Farmaceutico Bergamo Compared to Interferon Beta-1a (Rebif - Merck Serono) in Healthy Subjects

Healthy

Brazil
Azidus Brasil

Completed

Efficacy and Safety of Sodium Heparin (Hipolabor) in Patients (HEPSBCCV0109)

Cardiac Surgery

Brazil
Azidus Brasil

Completed

Efficacy and Safety of Sodium Heparin in Patients (Cristália)

Cardiac Surgery

Brazil
Azidus Brasil

Unknown

PK and PD Study After Single Dose, Intravenous Administration of Two Epoetin Alfa, Eritromax and Eprex, in Healthy Subjects

Healthy

Brazil
Azidus Brasil

Unknown

PHARMACODYNAMICS ASSESSMENT PRODUCT HEPARIN SODIUM (INTRAVENOUSLY) OF THE SWINE 5.000UI/ML OF BLAU FARMACÊUTICA S/A IN HEALTHY SUBJECTS IN COMPARISON OF SODIUM HEPARIN APP PHARMACEUTICALS

Healthy

Brazil
Azidus Brasil

Unknown

Study With Chondroitin Sulfate and Glucosamine Sulfate (in Dosage Capsule and Sachet) in Treating Osteoarthritis

Osteoarthritis
Azidus Brasil

Unknown

Randomized Study for Effectiveness and Safety Evaluation of Dexamethasone 0.5 mg + Fumarate Clemastine 1 mg Compared to Dexamethasone 0.5 mg in Patients With Allergic Dermatitis

Allergy | Dermatitis
Azidus Brasil

Unknown

Efficacy And Safety Of Unfractionated Heparin In Patients With Cardiovascular Surgery Using Cardiopulmonary Bypass

Prevention of Venous Thromboembolism

Brazil
Azidus Brasil

Unknown

Comparative Efficacy of the Suppository Versus Guaiacol Suppository Versus Guaifenesin Syrup in Pediatric Patients With Cough Due the Infectious Origin

Cough

Brazil
Azidus Brasil

Unknown

Efficacy and Safety of Sodium Heparin in Patients Submitted to Heart Surgery Using Bypass

Cardiac Surgery

Brazil
Azidus Brasil

Unknown

Comparative Efficacy of Two Preparations of the Association Diosmin (450 mg) + Hesperidin (50 mg) in the Treatment of Chronic Venous Insufficiency (CVI)

Venous Insufficiency

Brazil
Azidus Brasil

Unknown

Efficacy of Sodium Heparin for Prophylaxis of Venous Thromboembolism in Surgical Patients

Venous Thromboembolism

Brazil
Azidus Brasil

Unknown

Efficacy Maxinom® And Maxitrol® in Reducing The Signs And Symptoms Of Acute Bacterial Conjunctivitis

Bacterial Conjunctivitis | Acute

Brazil

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