Clinical Trials Sponsored by Arnold Ventures

Total 317 results

GlaxoSmithKline
Medicines for Malaria Venture

Completed

Assessment of Any Potential Retinal Effects of Tafenoquine (TQ)

Malaria, Vivax

United States
GlaxoSmithKline
Medicines for Malaria Venture

Completed

A Study to Evaluate the Pharmacokinetics of a Single Dose of Tafenoquine Co-administered With Either Artemether + Lumefantrine or Dihydroartemisinin + Piperaquine Tetraphosphate

Malaria, Vivax

United States
GlaxoSmithKline
Medicines for Malaria Venture

Completed

Tafenoquine/Chloroquine DDI Study

Malaria

United States
GlaxoSmithKline
Medicines for Malaria Venture

Completed

G6PD (Glucose-6-phosphate Dehydrogenase) Study to Evaluate Hemolysis Potential of TFQ (Tafenoquine)

Malaria

Thailand
Sanofi
Medicines for Malaria Venture

Terminated

To Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of a Single Dose Regimen of Ferroquine and Artefenomel in Adults and Children With Uncomplicated Plasmodium Falciparum Malaria (FALCI)

Plasmodium Falciparum Infection

Benin, Burkina Faso, Gabon, Kenya, Mozambique, Uganda, Vietnam
GlaxoSmithKline
Medicines for Malaria Venture

Completed

A Pharmacokinetics, Safety and Efficacy Study of Tafenoquine (TQ) in Pediatric Subjects With Plasmodium Vivax (P. Vivax) Malaria

Malaria, Vivax

Vietnam, Colombia
Daisy Pharma Opioid Venture, LLC

Unknown

Dronabinol Opioid Sparing Evaluation (DOSE) Trial

Chronic Pain

United States
GlaxoSmithKline
Medicines for Malaria Venture

Completed

Single-Blind, Placebo-Controlled, Randomized Study Testing Single Ascending Doses Of GSK369796 In Healthy Subjects

Malaria

United Kingdom
Sanofi
Medicines for Malaria Venture

Completed

Artesunate Plus Amodiaquine in Malaria in Cote d'Ivoire

Malaria

Côte D'Ivoire
Amy Arnold
American Heart Association

Recruiting

Angiotensin 1-7 in Obesity Hypertension

Hypertension | Obesity

United States
San Diego Veterans Healthcare System
Inflammagen/Leading Ventures

Terminated

Single Dose Enteral Tranexamic Acid in Critically Ill Patients

Sepsis | Shock | Critical Illness | Hypotension

United States
Fundação Altino Ventura

Completed

Artificial Tears Versus Preservative Free Ketorolac Trometamol 0.45% for Acute Viral Conjunctivitis

Conjunctivitis, Viral

Brazil
Ventrus Biosciences, Inc

Completed

Efficacy and Safety Study With Diltiazem Hydrochloride Cream to Treat Anal Fissures

Chronic Anal Fissures

United States
Ventrus Biosciences, Inc

Unknown

Topical Safety Study of Topical Diltiazem Hydrochloride

Diltiazem Skin Sensitivity.

United States
Ventrus Biosciences, Inc

Unknown

An Open-Label, Single- and Multi-Dose Pharmacokinetic (PK) Study of Oral Diltiazem and Topical Diltiazem Hydrochloride

Adult Subjects With Anal Fissures.

United States
Fundação Altino Ventura

Completed

Cataract Surgery With Intracameral Triamcinolone in Infants

Cataract

Brazil
NovoBliss Research Pvt Ltd
ZYWIE VENTURES PRIVATE LIMITED

Completed

A Clinical Study to Assess the Safety and Effectiveness of Plant Based Biotin in Healthy Human Subjects With Thin, Dry, and Brittle Hair

Hair Thinning | Hair Brittle | Dry Hair

India
University of California, Davis
The Arnold P. Gold Foundation

Completed

Use of Theater to Invoke Empathy and Reduce Bias in Medical Students

Medical Student Bias

United States
Ventrus Biosciences, Inc

Terminated

Efficacy and Safety Study to Treat Subjects With Symptomatic Internal Hemorrhoids (VEN309)

Internal Hemorrhoids

United States
Ventrus Biosciences, Inc

Unknown

A 21-Day Topical Safety Study of Diltiazem Hydrochloride Using a Cumulative Irritant Patch Test Design

Skin Irritation

United States
Ventrus Biosciences, Inc

Completed

Efficacy Study of Iferanserin to Treat Hemorrhoids

Hemorrhoids

Germany
Aventure AB
Glucanova AB

Completed

Effects of a Whole Grain Cereal Product on Blood Glucose Response After 3 Consecutive Meals

Blood Glucose

Sweden
Lund University
Vinnova; Öste Venture AB

Completed

Dietary Fibre and Metabolic Benefits

Glucose Tolerance

Sweden
GlaxoSmithKline
Parexel; Medicines for Malaria Venture

Completed

A Study to Assess the Effects of Dissolution Profile on the Pharmacokinetics of Single Oral Doses of Tafenoquine Tablets and Tafenoquine Stable Isotope Labelled Solution

Malaria, Vivax

United States
Medicines for Malaria Venture
Quotient Clinical

Completed

Bioavailability Study of Oral OZ439 Prototype Granule Formulations Administered With Piperaquine Phosphate (PQP) Tablets

Malaria

United Kingdom
Gamida Cell -Teva Joint Venture Ltd.

Completed

Efficacy and Safety Study of StemEx®, to Treat Subjects With High Risk Hematologic Malignancies, Following Myeloablative Therapy (ExCell)

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Non-Hodgkin's Lymphoma | Chronic Myeloid Leukemia | Hematologic Malignancies | Hodgkin's Disease | Lymphoid Leukemia

United States, Israel, Hungary, Italy, Spain
Oregon Health and Science University
Laura and John Arnold Foundation

Completed

Pharmacists Expand Access to Reproductive heaLthcare (PEARL)

Contraception

United States
Susanne Arnold
Kentucky Lung Cancer Research Program

Completed

Effects of Carboplatin and Gemcitabine on Stage IIIB Pleural Effusion and Stage IV Lung Cancer

Stage IIIB Non-small Cell Lung Cancer | Stage IV Non-small Cell Lung Cancer

United States
Medicines for Malaria Venture
Quotient Clinical

Completed

Bioavailability Study of Oral OZ439 Prototype Formulations Administered With Piperaquine Phosphate (PQP)

Malaria

United Kingdom
Medicines for Malaria Venture
Mahidol University

Completed

Efficacy, Tolerability, PK of OZ439 in Adults With Acute, Uncomplicated P.Falciparum or Vivax Malaria Mono-infection

Malaria, Falciparum | Malaria, Vivax
Treague Ltd
Medicines for Malaria Venture

Completed

Study to Investigate the Safety, Tolerability and Pharmacokinetics of AD 452 [(+)-Mefloquine] Compared With Racemic Mefloquine

Healthy Subjects

United Kingdom
NYU Langone Health
The Rainer Arnhold Foundation

Completed

Prevention Trial to Achieve Cardiovascular Targets (IMPACT)

Coronary Artery Disease | Hypertension | Obesity | Diabetes | Peripheral Arterial Disease | Hyperlipidemia | Prediabetes

United States
Elizabeth Arnold
Patient-Centered Outcomes Research Institute

Recruiting

Preventing Suicide Among Sexual and Gender Diverse Young Adults in Primary Care in Texas

Suicidal Ideation | Suicide

United States
Susanne Arnold
United States Department of Defense

Completed

Study of Lung Cancer in Appalachian Kentucky: The Role of Environmental Carcinogens

Lung Cancer

United States
Susanne Arnold
Kentucky Lung Cancer Research Program

Terminated

Phase I Trial of Docetaxel and Low-Dose Fractionated Radiation in the Treatment of Metastatic or Recurrent NSCLC

Non-Small Cell Lung Cancer

United States
Ventus Medical, Inc.

Completed

Extension Study of Original Protocol AERO C009 for Obstructive Sleep Apnea-hypopnea (AERO C009E)

Obstructive Sleep Apnea | Obstructive Sleep Apnea Hypopnea | OSAH

United States
Ventus Medical, Inc.

Completed

Randomized Study of Provent Versus Sham Device to Treat Obstructive Sleep Apnea (AERO)

OSA | Obstructive Sleep Apnea Hypopnea | OSAH

United States
ProgenaBiome
Ventura Clinical Trials

Not yet recruiting

Familial Fecal Microbiota Transplant for the Treatment of Subjects With Autism Spectrum Disorders

Autism Spectrum Disorder | Autism

United States
Mathematica Policy Research, Inc.
University of Pennsylvania; University of California, San Francisco; Arnold Ventures and other collaborators

Active, not recruiting

Transitional Care Model Evaluation 2020 (TCM2020)

Pneumonia | COPD | CHF - Congestive Heart Failure

United States
Albert Einstein College of Medicine
Laura and John Arnold Foundation; Vireo Health

Completed

Does Medical Cannabis Reduce Opioid Use in Adults With Pain (ReLeaf-E)

Chronic Pain | Opioid Use | Marijuana

United States
L. Eugene Arnold
National Institute of Mental Health (NIMH)

Completed

Omega-3 and Therapy Study for Depression (OATS)

Depression

United States
Medicines for Malaria Venture
Richmond Pharmacology Limited

Completed

Atoguanil BA Study

Bioavailability

United Kingdom
Medicines for Malaria Venture
Shin Poong Pharmaceuticals

Completed

Pyronaridine Artesunate (3:1) in Children and Adults With Acute Plasmodium Vivax Malaria

Malaria

Indonesia, Cambodia, India, Thailand
Medicines for Malaria Venture
Shin Poong Pharmaceuticals

Completed

Pyronaridine - Artesunate (3:1) Versus Mefloquine Plus Artesunate in Plasmodium Falciparum Malaria Patients

Falciparum Malaria

Cambodia, India, Thailand, Burkina Faso, Côte D'Ivoire, Tanzania, Vietnam
Medicines for Malaria Venture
Richmond Pharmacology Limited

Completed

Determine the Tolerability and Safety of Atovaquone-proguanil (ATV-PG) Co-administered With Amodiaquine (AQ)

Malaria

United Kingdom
Medicines for Malaria Venture
Richmond Pharmacology Limited

Completed

A Study to Evaluate the Pharmacokinetics of Oral Formulations of MMV390048 Administered Fasted to Healthy Volunteers

Malaria

United Kingdom
Medicines for Malaria Venture
Richmond Pharmacology Limited

Completed

A FIH Study to Investigate the Safety, Tolerability and PK of P218

Malaria

United Kingdom
Novartis Pharmaceuticals
Medicine for Malaria Venture

Terminated

Effectiveness of KAE609 in Reducing Asexual & Sexual Blood-stage P.Falciparum Infection & Infectivity to Mosquitos

Plasmodium Falciparum Malaria

Australia
Novartis Pharmaceuticals
Medicines for Malaria Venture

Completed

Efficacy, Safety and Pharmacokinetics of Artemether-lumefantrine Dispersible Tablet in the Treatment of Malaria in Infants < 5 kg

Acute Uncomplicated Falciparum Malaria

Burkina Faso, Benin, Congo, Nigeria, Togo
Medicines for Malaria Venture
Shin Poong Pharmaceuticals

Completed

Drug Interaction Study of Pyronaridine-artesunate & Metoprolol, & Redosing Study of Pyronaridine-artesunate

Malaria

Switzerland

Clinical Trials Sponsored by Arnold Ventures

Sponsors and Collaborators

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CROs in Serbia

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