Clinical Trials Sponsored by Karuna Therapeutics

Total 6753 results

Arena Pharmaceuticals

Terminated

Efficacy and Safety of APD334 in Patients With Pyoderma Gangrenosum

Pyoderma Gangrenosum

Australia, New Zealand
Arena Pharmaceuticals

Completed

Safety and Efficacy of Etrasimod (APD334) in Patients With Ulcerative Colitis

Ulcerative Colitis

United States, Australia, Austria, Belgium, Bulgaria, Canada, Czechia, France, Germany, Hungary, Israel, Korea, Republic of, Latvia, Lithuania, New Zealand, Poland, Romania, Russian Federation, Spain, Ukraine, United Kingdom
Arena Pharmaceuticals

Completed

A Study to Evaluate the Effect of Lorcaserin Hydrochloride on Smoking Cessation

Smoking Cessation

United States
Arena Pharmaceuticals

Completed

Single-dose Safety Study of APD916 in Healthy Volunteers

Narcolepsy With or Without Cataplexy

United States
Arena Pharmaceuticals

Completed

Extension Study of APD334-003 in Patients With Moderately to Severely Active Ulcerative Colitis

Ulcerative Colitis

United States, Australia, Austria, Belgium, Bulgaria, Canada, Czechia, France, Germany, Hungary, Israel, Korea, Republic of, Latvia, Lithuania, New Zealand, Poland, Romania, Russian Federation, Spain, Ukraine, United Kingdom
Arena Pharmaceuticals

Terminated

Effect of Olorinab on Gastrointestinal Transit in Patients With Irritable Bowel Syndrome

Irritable Bowel Syndrome

United States
Arena Pharmaceuticals

Completed

Subjective Study to Assess the Efficacy of APD125 in Patients With Sleep Maintenance Insomnia

Primary Insomnia

United States
Arena Pharmaceuticals

Completed

Safety and Efficacy Study of APD125 in Patient With Insomnia

Insomnia

United States
Akebia Therapeutics
Cyclerion Therapeutics

Completed

A Study to Evaluate the Soluble Guanylate Cyclase (sGC) Stimulator IW-1973 in Diabetic Nephropathy / Diabetic Kidney Disease as Measured by Albuminuria

Type 2 Diabetes Mellitus With Diabetic Nephropathy

United States
Akebia Therapeutics
Cyclerion Therapeutics

Completed

A Study of the Effect of IW-1973 on the Exercise Capacity of Patients With Heart Failure With Preserved Ejection Fraction (HFpEF) (CAPACITY-HFpEF)

Heart Failure With Preserved Ejection Fraction

United States, Canada
Aruna Nathan
Children's Hospital of Philadelphia

Terminated

Sedation With Dexmedetomidine During Cardiac Catheterization

Pulmonary Hypertension

United States
Eikon Therapeutics
Impact Therapeutics, Inc.

Recruiting

A First-in-human Study of PARP1 Selective Inhibitor, IMP1734, in Participants With Advanced Solid Tumors

Advanced Solid Tumor

Australia, United States
CRISPR Therapeutics AG

Active, not recruiting

A Safety and Efficacy Study Evaluating CTX130 in Subjects With Relapsed or Refractory Renal Cell Carcinoma (COBALT-RCC)

Renal Cell Carcinoma

United States, Australia, Canada, Netherlands
APRINOIA Therapeutics, LLC

Active, not recruiting

A First-in-Human Study to Assess Single Doses of APNmAb005 in Healthy Participants

Alzheimer Disease | Tauopathies | Healthy Volunteers

United States
University of La Laguna

Recruiting

Telemedicine-based Model of Care for the Management of Hepatitis C Infected Patients

Hepatitis C | Telemedicine

Spain
University of La Laguna

Completed

Integrating Hepatitis C Screening With Dried Blood Spot Testing Into Colorectal Cancer Screening

Hepatitis C Virus Infection

Spain
Kaunas University of Medicine

Completed

Prevention of Prostate Cancer With Dutasteride in Case of High Grade PIN Neoplasia

Prostate Cancer

Lithuania
Omer Karaca
Baskent University

Completed

Ultrasound-Guided Versus Conventional Method for Caudal Block

Ultrasound Therapy; Complications

Turkey
Faculdade Evangelica do Parana

Completed

Respiratory Muscle Stretching in Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease

Brazil
Kaunas University of Medicine

Unknown

Preoperative Chemoradiation Versus Short Term Radiation Alone With Delayed Surgery for Stage II and III Resectable Rectal Cancer

Primary Rectal Cancer

Lithuania
CRISPR Therapeutics AG

Recruiting

A Safety and Efficacy Study Evaluating CTX131 in Adult Subjects With Relapsed or Refractory Solid Tumors

Clear Cell Renal Cell Carcinoma | Pancreatic Adenocarcinoma | Cervical Carcinoma | Malignant Pleural Mesothelioma | Esophageal Carcinoma

United States
CRISPR Therapeutics AG

Active, not recruiting

A Safety and Efficacy Study Evaluating CTX130 in Subjects With Relapsed or Refractory T or B Cell Malignancies (COBALT-LYM)

T Cell Lymphoma

United States, Australia, Canada
CRISPR Therapeutics AG

Active, not recruiting

A Safety and Efficacy Study Evaluating CTX110 in Subjects With Relapsed or Refractory B-Cell Malignancies (CARBON)

B-cell Lymphoma | Non-Hodgkin Lymphoma | B-cell Malignancy | Adult B Cell ALL

United States, Spain, Canada, France, Germany, Australia
Bacainn Therapeutics, Inc.

Completed

A Phase 1, Single-Ascending-Dose Study of BT051 in Healthy Subjects

Healthy Volunteers

United States
Celsus Therapeutics PLC

Terminated

Double-Blind, Trial to Evaluate the Safety and Efficacy of MRX-6 Cream 2% (C012013)

Atopic Dermatitis

Israel
CRISPR Therapeutics AG

Recruiting

A Safety and Efficacy Study Evaluating CTX112 in Subjects With Relapsed or Refractory B-Cell Malignancies

Follicular Lymphoma | B-cell Lymphoma | Mantle Cell Lymphoma | Marginal Zone Lymphoma | Non-Hodgkin Lymphoma | B-cell Malignancy | Large B-cell Lymphoma | Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)

United States
CRISPR Therapeutics AG

Enrolling by invitation

A Long-term Follow-up Study of Subjects Who Received CRISPR CAR T Cellular Therapies

Hematologic Malignancy | Solid Malignancy

United States, Australia
CRISPR Therapeutics AG

Active, not recruiting

A Safety and Efficacy Study Evaluating CTX120 in Subjects With Relapsed or Refractory Multiple Myeloma

Multiple Myeloma

United States, Spain, Australia, Canada
APRINOIA Therapeutics, LLC

Active, not recruiting

Evaluation of [18F]APN-1607 PET Uptake in Alzheimer's Disease Patients Compared With Healthy Subjects

Healthy Volunteers | Alzheimer's Disease | Mild Cognitive Impairment Due to Alzheimer's Disease

United States
University of La Laguna

Not yet recruiting

Artificial Intelligence and Bowel Cleansing Quality (CALPER3)

Cleansing Quality of the Colon

Spain
University of La Laguna

Recruiting

Retrieval of Hepatitis C Patients Lost to Follow-up

Hepatitis C

Spain
PiLeJe
BioFortis

Terminated

Prevention of Recurrent Vulvovaginal Candidiasis With Lactibiane Candisis 5M®

Vaginal Candidiasis

France
Faculdade Evangelica do Parana

Completed

Neuromuscular Electrical Therapy in Venous Ulcers

Chronic Venous Insufficiency

Brazil
Kaunas University of Medicine

Unknown

Long or Very Long-Limb Gastric Bypass in Superobese

Obesity

Lithuania
Kaunas University of Medicine

Completed

Risk Factors for Recurrent Urinary Tract Infection in Children

Cystitis | Urinary Tract Infection | Pyelonephritis

Lithuania
Kaunas University of Medicine

Unknown

Investigation of Early Hormonotherapy Efficacy of Prostate Cancer

Prostate Cancer

Lithuania
University of La Laguna

Recruiting

Acceptance and Feasibility of Hepatitis c Screening Strategies in Social Insertion Centers (TGSS_CIS)

Hepatitis C Virus

Spain
University of La Laguna

Recruiting

Acceptance of Hepatitis C Screening by Self-testing in High Risk and General Population

Hepatitis C

Spain
University of La Laguna

Recruiting

Telemedicine for Linkage to Care People Who Injected Drugs With Hepatitis C

Hepatitis C Virus Infection

Spain
Faculdade Evangelica do Parana

Completed

Virtual Exercises in Patients With Parkinson's Disease.

Parkinson Disease

Brazil
Faculdade Evangelica do Parana

Completed

Inspiratory Muscle Training in Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease
Mauna Kea Technologies

Completed

Clinical Registry of nCLE in Masses and Cystic Tumors of the Pancreas, Lymph Nodes, Submucosal Lesions of the GI Tract (US-nCLE)

Pancreatic Neoplasms | Pancreatic Cancer | Lymphadenopathy | Pancreatic Cyst | GIST | Pancreatic Islet Cell Tumors | Pancreatic Adenoma | Lymph Node Mass

United States
Mauna Kea Technologies

Unknown

Clinical Evaluation Of Needle-based Confocal Laser Endomicroscopy in The Lymph Nodes Along With Masses and Cystic Tumors of the Pancreas (CONTACT)

Pancreatic Neoplasms | Pancreatic Cancer | Lymphadenopathy | Pancreatic Cyst | Pancreatic Islet Cell Tumors | Pancreatic Adenoma | Lymph Node

France
Skyline Therapeutics (US) Inc.

Recruiting

Phase I/II Study of SKG0106 Intravitreal Injection in Patients With Neovascular Age-related Macular Degeneration (nAMD)

Neovascular Age-related Macular Degeneration

China, United States
iCell Gene Therapeutics
iCar Bio Therapeutics

Recruiting

CD7 CAR-T Cell Treatment of Relapsed/Refractory CD7+ T -Acute Lymphoblastic Leukemia/ Lymphoma

Relapsed/Refractory, High Risk Hematologic Malignancies | T-ALL/Lymphoma

China
Carna Biosciences, Inc.

Recruiting

AS-1763 in Patients With Previously Treated CLL/SLL or Non-Hodgkin Lymphoma

Follicular Lymphoma | Waldenstrom Macroglobulinemia | Mantle Cell Lymphoma | Marginal Zone Lymphoma | Chronic Lymphocytic Leukemia | Non-Hodgkin Lymphoma | Small Lymphocytic Lymphoma | B-cell Malignancy

United States
Mauna Kea Technologies

Completed

Registry Trial to Determine pCLE Image Interpretation Criteria and Preliminary Accuracy in the Lung (BREATH)

Lung Neoplasms | Disorder Related to Lung Transplantation

United States
Mauna Kea Technologies

Completed

Probe-based and Needle-based Confocal Laser Endomicroscopy During Gynaecological Procedures.

Ovarian Cancer | Cervix Cancer | Endometrium Cancer | Carcinoma in Situ of Fallopian Tube

France
Mauna Kea Technologies

Completed

Needle-based Confocal Laser Endomicroscopy in Fluoroscopy-guided Procedures

Lung Percutaneous Biopsy | Liver Percutaneous Biopsy

France
Arthrosi Therapeutics

Recruiting

Phase 3 Evaluation of Efficacy and Safety of AR882 in Gout Patients

Hyperuricemia | Gout | Arthritis, Gouty | Gout Chronic

United States, Australia, New Zealand

Clinical Trials Sponsored by Karuna Therapeutics

Sponsors and Collaborators

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CROs in Uzbekistan

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