Clinical Trials Sponsored by Sandcastle Kids

Total 1476 results

St Stephens Aids Trust

Terminated

NNRTI/PI Toxicity Switch to Darunavir Study

HIV

United Kingdom
St Stephens Aids Trust

Completed

Atazanavir/Ritonavir and Darunavir/Ritonavir PK Tail Study

HIV Infections | HIV

United Kingdom
St Stephens Aids Trust

Completed

Double Protease Inhibitor to Darunavir Switch Study

HIV Infections

United Kingdom
St Stephens Aids Trust

Completed

Maraviroc 300 mg Twice Daily in HIV Negative Male Volunteers

HIV Infections

United Kingdom
St Stephens Aids Trust

Terminated

Pre-Exposure Prophylaxis Using TMC278LA

HIV Infections

United Kingdom
St Stephens Aids Trust

Completed

Pharmacokinetics (PK) Study of Once Daily Darunavir/Ritonavir and Twice and Once Daily Raltegravir in HIV-infected Subjects

HIV Infections

United Kingdom
St Stephens Aids Trust

Completed

TMC 125 Blood Levels Study

HIV Infections

United Kingdom
St Stephens Aids Trust

Completed

Cardiovascular Risk in HIV Patients Switching From a Boosted Protease Inhibitor (PI) to Dolutegravir (DTG)

HIV

Germany, Spain, France, United Kingdom, Belgium, Italy
St Stephens Aids Trust

Completed

Study in Healthy Volunteers of the Safety and Metabolism of Different Doses of the Anti-HIV Drug TMC278LA.

HIV Infection

United Kingdom
St Stephens Aids Trust

Completed

Open Label Trial of PEG-IFN, RBV & TVR vs. PEG-IFN & RBV Alone in Tx of HCV-1 in HIV-1 Co-infected Patients (CHAT) (CHAT)

HIV

United Kingdom
St Stephens Aids Trust

Completed

A Study to Assess Cerebrospinal Fluid INflammatory Markers After Addition of Maraviroc to MONotherapy Darunavir/Ritonavir - The CINAMMON Study (CINAMMON)

HIV

United Kingdom
St Stephens Aids Trust

Completed

A Two Way Cross Over Pharmacokinetic Interaction Study Between Raltegravir and Amlodipine in Healthy Volunteers

HIV

United Kingdom
St Stephens Aids Trust

Completed

The Effect of Hyperbilirubinemia on CV Disease, Neurocog Function and Renal Function (SSAT044)

HIV

United Kingdom
International AIDS Vaccine Initiative

Completed

Safety and Immunogenicity of TBC-M4, a MVA HIV Vaccine Alone or in a Prime-Boost Regimen With ADVAX DNA HIV Vaccine

HIV Infections

United Kingdom
International AIDS Vaccine Initiative

Completed

A Pilot Study of Pre-Exposure Prophylaxis (PrEP) to Evaluate Safety, Acceptability, and Adherence in At-risk Populations in Uganda, Africa

HIV Infection

Uganda
Yunnan AIDS Care Center

Unknown

Safety and Efficacy of Raltegravir+TDF+3TC in HBV/HIV Co-infected Patients

HIV Infections | HBV Coinfection

China
St Stephens Aids Trust

Withdrawn

Depot Contraception With and Without Lopinavir/Ritonavir

HIV Infection

United Kingdom
St Stephens Aids Trust

Completed

Raltegravir Insulin Sensitivity Study

HIV Infections

United Kingdom
International AIDS Vaccine Initiative

Completed

A Pilot Study of Pre-Exposure Prophylaxis (PrEP) to Evaluate Safety, Acceptability, and Adherence in At-Risk Populations in Kenya, Africa

HIV Infections

Kenya
St Stephens Aids Trust

Completed

Pilot Study Switching Individuals Receiving EFV With Continuing Central Nervous System Toxicity to TMC125

HIV

United Kingdom
Epividian
AIDS Healthcare Foundation

Completed

COVID-19 Quantitative Antibody Titers & Booster Vaccinations

COVID-19 | COVID-19 Vaccines | Immunogenicity, Vaccine

United States
St Stephens Aids Trust

Unknown

Targeted Clinical Strategies and Low Level Viraemia (LLV) in Boosted Protease Inhibitor Therapy

HIV

United Kingdom
St Stephens Aids Trust

Completed

A Pilot Study to Assess the Feasibility of Switching, Individuals Receiving Atripla With Continuing Central Nervous System (CNS) Toxicity, to a Fixed Dose Combination of Tenofovir/Emtricitabine/Rilpivirine

HIV

United Kingdom
St Stephens Aids Trust

Completed

The Pharmacology/Aging Clinic (SSAT041)

HIV Infection

United Kingdom
St Stephens Aids Trust

Completed

A Phase IV, Open-label Single-arm Study Investigating the Pharmacokinetics and Pharmacodynamics of the Antiretroviral Combination of Rilpivirine and Ritonavirboosted Darunavir in Therapy-naive HIV-1 Infected Patients.

HIV

United Kingdom
International AIDS Vaccine Initiative

Completed

Safety and Immunogenicity Study of SeV-G(NP) HIV Vaccine Administered Intranasally and Ad35-GRIN HIV Vaccine Given Intramuscularly in Prime-Boost Regimens in HIV-Uninfected Volunteers

HIV Infections

United Kingdom, Kenya, Rwanda
Kips Bay Medical, Inc.

Unknown

The eMESH 1 Feasibility Study (eMESH 1)

Atherosclerosis of Autologous Vein Coronary Artery Bypass Graft(s)

United States, United Kingdom, Czech Republic, Netherlands, France, Italy, Switzerland
St Stephens Aids Trust

Completed

Atripla to Raltegravir Switch Study for CNS Toxicity (SSAT036)

HIV Infection

United Kingdom
St Stephens Aids Trust

Completed

Men Who Have Sex With Men (MSM) Neurocog 1&2 Study (MSM Neurocog)

HIV Related Neurocognitive Impairment

United Kingdom
St Stephens Aids Trust

Unknown

Hydroxychloroquine for Discordant CD4 Responders on Highly Active Antiretroviral Therapy (HAART) (SSAT039)

HIV Infection

United Kingdom
St Stephens Aids Trust

Completed

Pharmacokinetics of Tenofovir and Tenofovir-diphosphate, Emtricitabine and Emtricitabine-triphosphate, and Rilpivirine Once Daily Over 14 Days Following Drug Intake Cessation in Healthy Volunteers

HIV

United Kingdom
St Stephens Aids Trust

Completed

PK Switch Efavirenz to Maraviroc in Patients Initially Suppressed on an Efavirenz-containing Regimen (SSAT033)

HIV Infection

United Kingdom
St Stephens Aids Trust

Terminated

Impact of Maraviroc on the Immune Function in HIV-1 Infected Subjects Receiving Immunisation With Novel Antigens

HIV Infections

United Kingdom
St Stephens Aids Trust

Completed

Raltegravir and Ezetimibe PK Study

HIV

United Kingdom
St Stephens Aids Trust

Completed

Abacavir Pharmacokinetic Study in the Absence/Presence of Darunavir/Ritonavir or Raltegravir in HIV-infected Subjects

HIV

United Kingdom
AIDS Arms Inc.
GlaxoSmithKline

Completed

Impact of Drug Therapy and Co-Morbidities on the Development of Renal Impairment in HIV-Infected Patients

HIV Infections | Kidney Failure | Human Immunodeficiency Viruses

United States
Holland Bloorview Kids Rehabilitation Hospital
Universidad de Costa Rica

Active, not recruiting

Video Gaming for Home Rehabilitation for Children With Hemiplegic Cerebral Palsy in Costa Rica

Hemiplegic Cerebral Palsy

Canada, Costa Rica
Queen Fabiola Children's University Hospital
The Belgian Kids' Fund

Unknown

Contribution of Attachment and Educational Practices in the Expression of ADHD in School-aged Children (CASPI-ADHD)

Attention Deficit Hyperactivity Disorder

Belgium
University of Toronto
Holland Bloorview Kids Rehabilitation Hospital; ErinoakKids

Unknown

Investigating Best Practices for Children With Cerebral Palsy: A Pilot Study of Two Approaches

Cerebral Palsy
St. Jude Children's Research Hospital
Cookies for Kids' Cancer

Terminated

Microtransplantation to Treat Refractory or Relapsed Hematologic Malignancies in Younger Patients

Acute Myeloid Leukemia (AML) | Myelodysplastic Syndrome (MDS)

United States
Chulalongkorn University
Thai Red Cross AIDS Research Centre; International AIDS Society

Completed

Youth-focused Strategies to Promote Adherence to Pre-exposure Prophylaxis Among Youth At-risk for HIV in Thailand (YouthPrEP)

HIV Prevention | Adherence, Medication | Adolescent Behavior | Mobile Health | Sexual Health

Thailand
Aaron Diamond AIDS Research Center

Unknown

A Study of Tucaresol in HIV-Infected Patients Who Are Taking Other Anti-HIV Drugs

HIV Infections

United States
Aaron Diamond AIDS Research Center

Completed

Placebo-Controlled Trial of Safety and Efficacy of Thalidomide in Patients With Infections Due to Mycobacterium and/or HIV

HIV Infections | Mycobacterium Avium-Intracellulare Infection | Tuberculosis, Mycobacterium Infection

United States
Thai Red Cross AIDS Research Centre
Verein Aids Life through TREAT Asia

Recruiting

Study on Anal Human Papillomavirus Infection and Anal Intraepithelial Neoplasia Among Men Who Have Sex With Men in Indonesia, Malaysia, and Thailand

HPV Testing

Thailand
Thai Red Cross AIDS Research Centre
amfAR, The Foundation for AIDS Research

Active, not recruiting

Exploration of the Neo-Vagina Study

HIV Infections | Transgender Women

Thailand
International AIDS Vaccine Initiative
University of Rochester; Aaron Diamond AIDS Research Center

Completed

Safety and Immunogenicity of a Modified Vaccinia Ankara (MVA) HIV Vaccine in HIV Uninfected Adults

HIV Infection

United States
Mahidol University
Thai AIDs society

Recruiting

Efficacy and Safety of Low-Dose Colchicine on Surrogate Markers of Cardiovascular Events in People Living With HIV Receiving Antiretroviral Therapy

HIV Infections | Inflammatory Markers | Colchicine Adverse Reaction

Thailand
Valley AIDS Council
Gilead Sciences

Not yet recruiting

Advanced HIV: Outcomes for Rapid ART (AHORA)

HIV-1-infection
Taiwan AIDS Nurse Society
GlaxoSmithKline

Unknown

Quality of Life of Taiwan People Living With HIV

HIV-1-infection

Taiwan
RAND
The AIDS Support Organization

Completed

SMS as an Incentive To Adhere (SITA) - An Intervention Communicating Social Norms by SMS to Improve ARV Adherence (SITA)

Human Immunodeficiency Virus

Uganda

3

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