Clinical Trials Sponsored by SmithKlinBeecham Biologicals

Total 977 results

HCW Biologics

Active, not recruiting

HCW9218 for Advanced Pancreatic Cancer

Advanced Pancreatic Carcinoma

United States
Heat Biologics

Withdrawn

A Phase 1 Study of PTX-35 in Healthy Volunteers

Healthy Volunteer
GenSight Biologics

Completed

Efficacy Study of GS010 for Treatment of Vision Loss From 7 Months to 1 Year From Onset in LHON Due to the ND4 Mutation (REVERSE) (REVERSE)

Optic, Atrophy, Hereditary, Leber

United Kingdom, United States, Germany, Italy, France
rEVO Biologics

Completed

A Phase I Safety, Pharmacokinetics and Pharmacodynamics Study of Recombinant Factor VIIa in Adult Patients With Hemophilia A or B (rhFVIIa)

Hemophilia

Netherlands, United States
RenaMed Biologics

Terminated

Study to Evaluate the Safety and Efficacy of the Renal Assist Device in Patients With Acute Renal Failure

Kidney Failure, Acute

United States
rEVO Biologics

Completed

Assess Incidence of Deep Vein Thrombosis(DVT)Following Administration of Recombinant Human Antithrombin (rhAT) to Hereditary Antithrombin(AT) Deficient Patients in High Risk Situations. (rhAT)

Antithrombin Deficiency, Congenital

France, United Kingdom, Germany, United States, Sweden, Italy
Hualan Biological Engineering, Inc.

Completed

Clinical Trial of the Inactivated Influenza Vaccine (0.25ml Formulation for Pediatric Use)

Influenza

China
Hualan Biological Engineering, Inc.

Completed

Clinical Trial of Group ACYW135 Meningococcal Polysaccharide Vaccine 001

Meningitis
GlaxoSmithKline
Biological E. Limited

Recruiting

Safety and Immunogenicity of a Novel Conjugate Vaccine Against Salmonella Typhi and Salmonella Paratyphi A in Healthy Adults

Typhoid Fever

Belgium
Hualan Biological Engineering, Inc.

Completed

Phase IV Clinical Trial of an Inactivated Influenza Split Vaccine

Human Influenza

China
Hualan Biological Engineering, Inc.

Completed

Clinical Trial of Group ACYW135 Meningococcal Polysaccharide Vaccine 003

Meningitis
Hualan Biological Engineering, Inc.

Completed

Clinical Trial of Group ACYW135 Meningococcal Polysaccharide Vaccine 002

Meningitis
Hualan Biological Engineering, Inc.

Completed

Clinical Trial of Inactivated Influenza Vaccine (0.5ml Formulation)

Influenza

China
Hualan Biological Engineering, Inc.

Completed

Post-marketing Clinical Observation of an Inactivated Influenza Split Vaccine

Human Influenza

China
University Hospital, Lille
Grifols Biologicals, LLC

Completed

Study of Infections in Patients With Autoimmune Diseases Treated With Rituximab (EXPRIME)

Autoimmune Diseases

France
Instituto Grifols, S.A.

Completed

Efficacy and Safety of Plasma Exchange With Albumin in Patients With Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis

Spain
General Biologicals Corporation
Mackay Memorial Hospital

Unknown

Development of a Molecular Diagnosing Platform for Monitoring Oral Hygiene in Diabetic Patients

Diabetes Mellitus | Periodontal Diseases

Taiwan
Instituto Grifols, S.A.

Completed

Safety and Efficacy Study of Fibrin Sealant Grifols as an Adjunct to Hemostasis During Peripheral Vascular Surgery

Vascular Surgical Bleeding

United States, Hungary, Russian Federation, Serbia
Instituto Grifols, S.A.
Grifols Biologicals, LLC

Completed

Efficacy and Safety of Plasma Exchange With 5% Albumin in Beta-amyloid Peptide Clearance in Cerebral Spinal Fluid

Alzheimer's Disease

Spain, United States
Instituto Grifols, S.A.

Completed

Efficacy and Safety of Niuliva® for the Prevention of Hepatitis B Virus Recurrence in Newly Orthotopic Liver Transplant Recipients

Liver Transplantation | Hepatitis B

Italy
Instituto Grifols, S.A.

Completed

Clinical Trial in Patients Diagnosed With Immune Thrombocytopenic Purpura (ITP)

Immune (Idiopathic) Thrombocytopenic Purpura

Spain, Russian Federation, United Kingdom
Instituto Grifols, S.A.

Completed

Efficacy and Safety of Intramuscular HBIG Grifols for the Prevention of Recurrence After Liver Transplantation

Hepatitis B, Chronic

Italy
University of Washington
Grifols Biologicals, LLC

Withdrawn

Monotherapy IVIG Gamunex-C for HMG-CoA Reductase Auto-Antibody Positive Necrotizing Myopathy Treatment (The MIGHT Trial)

Immune-Mediated Necrotizing Myopathy

United States
Grifols Therapeutics LLC
Grifols Biologicals, LLC

Terminated

Alphanate in Immune Tolerance Induction Therapy

Hemophilia A, Congenital

United States, Spain, Italy, India, Canada, Russian Federation
Grifols Therapeutics LLC
Grifols Biologicals, LLC

Completed

Efficacy and Safety of Plasma Exchange With Albutein® 5% in Participants With Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis

United States
Instituto Grifols, S.A.
Grifols Biologicals, LLC

Completed

A Study to Evaluate Albumin and Immunoglobulin in Alzheimer's Disease (AMBAR)

Alzheimer's Disease

Spain, United States
Instituto Grifols, S.A.

Completed

Safety and Efficacy of Topical Thrombin (Human) Grifols as an Adjunct to Hemostasis During Surgery

Hemostasis

United States
Grifols Biologicals, LLC
Instituto Grifols, S.A.

Completed

IGIV Study for Chronic ITP Patients Ages 3-70

Idiopathic Thrombocytopenic Purpura

United States, India, Puerto Rico, Canada
Grifols Biologicals, LLC
Instituto Grifols, S.A.

Completed

Safety and Efficacy of Fibrin Sealant Grifols (FS Grifols) During Soft Tissue Open Surgeries

Soft Tissue Surgical Bleeding

United States, Hungary, Serbia
Instituto Grifols, S.A.

Completed

Safety and Efficacy of Fibrin Sealant Grifols (FS Grifols) During Parenchymous Tissue Open Surgeries

Parenchymous Tissue Surgical Bleeding

United States, Hungary, Russian Federation, Serbia
Instituto Grifols, S.A.

Completed

Safety and Efficacy Study of Flebogamma 5% DIF IGIV in Pediatric Subjects

Primary Immune Deficiency Disease

United States
Instituto Grifols, S.A.

Completed

Use of Antithrombin in Cardiac Surgery With Cardiopulmonary Bypass

Coronary Artery Bypass | Acquired Antithrombin III Deficiency

Italy
Instituto Grifols, S.A.

Completed

Safety and Efficacy Study of Fibrin Sealant Grifols Evaluated as an Adjunct to Hemostasis

Target Bleeding Site During Peripheral Vascular Surgery

Canada, United Kingdom, Spain
Instituto Grifols, S.A.

Completed

Evaluation of Serum Levels and Pharmacokinetics of a New Hepatitis B Immune Globulin Following Liver Transplantation

Hepatitis B, Chronic

Spain
Burst Biologics

Unknown

Burst Biologics Foot and Ankle Registry

Foot and Ankle Disorders | Ankle Fusion, Osteotomy

United States
Synermore Biologics Co., Ltd.
Synermore Biologics USA Limited

Active, not recruiting

A Study to Find the MTD of SYN125 in People With Solid Tumors and the MTD of SYN125 With a Fixed Dose of SYN004 in People in Patients With Epithelial Cancers With EGFR Expressions

Solid Tumor | Epithelial Carcinoma

United States
EXO Biologics S.A.

Recruiting

Safety and Efficacy of MSC-EVs in the Prevention of BPD in Extremely Preterm Infants (EVENEW)

Bronchopulmonary Dysplasia

Italy, Belgium
CanSino Biologics Inc.

Recruiting

A Clinical Trial of Adsorbed Cell-free DPT Vaccine (5-component) (for People Aged 6 Years and Above)

Pertussis | Tetanus | Diphtheria

China
Direct Biologics, LLC

Recruiting

Study of ExoFlo for the Treatment of Perianal Fistulas

Crohn's Disease | Perianal Fistula

United States
Turnstone Biologics, Corp.

Recruiting

A Study of TBio-4101 (TIL) and Pembrolizumab in Patients With Advanced Solid Tumors (STARLING)

Breast Cancer | Colorectal Cancer | Non-Small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Uveal Melanoma | Cutaneous Melanoma

United States, Canada
Direct Biologics, LLC

Recruiting

Study of ExoFlo for the Treatment of Medically Refractory Ulcerative Colitis

Inflammatory Bowel Diseases | Ulcerative Colitis

United States
Direct Biologics, LLC

Not yet recruiting

Bone Marrow Mesenchymal Stem Cell Derived Extracellular Vesicles Infusion Treatment for ARDS (EXIT-ARDS)

ARDS, Human
Direct Biologics, LLC

Not yet recruiting

ExoFlo™ Infusion for Post-Acute COVID-19 and Chronic Post-COVID-19 Syndrome

Covid19 | Dyspnea | Postviral Syndrome
Aesculap Biologics, LLC

Recruiting

NOVOCART 3D Treatment Following Microfracture Failure

Articular Cartilage Defect

United States
CanSino Biologics Inc.

Active, not recruiting

A Clinical Trial of ACYW135 Group Meningococcal Polysaccharide Conjugate Vaccine (CRM197 Vector) in a 4 to 6 Year-old Population

Epidemic Meningitis

China
VIVEX Biologics, Inc.

Terminated

Wound Healing Following Penile Prosthesis Implant

Erectile Dysfunction

United States
Direct Biologics, LLC

Withdrawn

Extracellular Vesicles Infusion Treatment for Mild-to-Moderate COVID-19

COVID-19
Direct Biologics, LLC

Available

Expanded Access for Use of ExoFlo in Abdominal Solid Organ Transplant Patients

Solid Organ Transplant Rejection | Organ Rejection Transplants | Organ Rejection

United States
Direct Biologics, LLC

Available

Expanded Access for Use of bmMSC-Derived Extracellular Vesicles in Patients With COVID-19 Associated ARDS

Hypoxia | Covid19 | ARDS | Cytokine Storm
CanSino Biologics Inc.

Active, not recruiting

Clinical Trial of Recombinant Pneumococcal Protein Vaccine

Respiratory Tract Infections | Respiratory Tract Diseases | Pneumonia

China

Clinical Trials Sponsored by SmithKlinBeecham Biologicals

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