Search clinical trials for: Antifungal prophylaxis

Total 5894 results

Institute of Tropical Medicine, Belgium
Drugs for Neglected Diseases; Medecins Sans Frontieres, Netherlands; Addis Ababa... and other collaborators

Completed

Prophylaxis of Visceral Leishmaniasis Relapses in HIV Co-infected Patients With Pentamidine: a Cohort Study

HIV-infection/Aids | Visceral Leishmaniosis

Ethiopia
Dana-Farber Cancer Institute
National Cancer Institute (NCI); Massachusetts General Hospital; Brigham and...

Completed

Tacrolimus/Sirolimus/Methotrexate vs Tacrolimus/Methotrexate or Cyclosporine/Mycophenolate Mofetil for GVHD Prophylaxis After Reduced Intensity Allogeneic Stem Cell Transplantation for Patients With Lymphoma

Hodgkin Lymphoma | Non-hodgkin Lymphoma

United States
Mayne Pharma International Pty Ltd

Completed

Bioavailability Study of Lozanoc™ 65 mg Itraconazole Capsules in Patients Requiring Prophylaxis

Neutropenia

Australia
Mayne Pharma International Pty Ltd

Completed

Steady-State Comparative Bioavailability Study in Prophylaxis Patients of Lozanoc® 50 mg With Sporanox® 100 mg

Neutropenia

Australia
Astellas Pharma Singapore Pte. Ltd.

Completed

Non-interventional Study for Prevention and Treatment of Fungal Infections in Paediatric Patients in Asia/Oceania - ERADICATE Study

Invasive Fungal Infections

Hong Kong, Korea, Republic of, Singapore, Taiwan, Thailand
Universidade Federal do Rio de Janeiro

Completed

Anti-mold Azole in the Prophylaxis for Invasive Fusariosis (Fusarproph)

Onychomycosis | Fusariosis

Brazil
Jennifer E. Schwartz
Millennium Pharmaceuticals, Inc.

Completed

A Study Using Tacrolimus, Sirolimus and Bortezomib as Acute Graft Versus Host Disease (GVHD) Prophylaxis in Allogeneic Peripheral Blood Stem Cell (PBSC) Transplantation

Graft vs Host Disease | Peripheral Blood Stem Cell Transplantation | Transplantation, Homologous

United States
Fujian Medical University

Unknown

Posaconazole vs Itraconazole in Preventing IFD Post-HSCT

IFD Post-HSCT

China
Bayside Health
Merck Sharp & Dohme LLC

Unknown

Universal Prophylaxis Versus Pre-emptive Therapy With Posaconazole Post-Lung Transplant (UPPRITE)

Fungal Infection

Australia
Children's Hospital Medical Center, Cincinnati
Astellas Pharma Inc

Terminated

A Pharmacokinetic Study of Pediatric Micafungin Prophylaxis (Micafungin)

Cancer | Immunocompromised | Bone Marrow Transplant

United States
Memorial Sloan Kettering Cancer Center
Astellas Pharma US, Inc.

Completed

Posaconazole Versus Micafungin for Prophylaxis Against Invasive Fungal Infections During Neutropenia in Patients Undergoing Chemotherapy for Acute Myelogenous Leukemia, Acute Lymphocytic Leukemia or Myelodysplastic Syndrome

Myelodysplastic Syndrome | Acute Myelogenous Leukemia

United States
F2G Biotech GmbH
University Hospital of Cologne

Withdrawn

Study on Safety and Pharmacokinetics of Intravenous F901318 for Fungal Prophylaxis in AML Patients (SAFEGUARD)

Acute Myeloid Leukemia | Pulmonary Aspergillosis - Invasive
Dr Cipto Mangunkusumo General Hospital

Completed

Oral Nystatin Prophylaxis to Prevent Systemic Fungal Infection in Very Low Birth Weight Preterm Infants

Fungal Infections Systemic
National Cancer Institute (NCI)

Completed

Low-Intensity Stem Cell Transplantation With Multiple Lymphocyte Infusions to Treat Advanced Kidney Cancer

Renal Cell Carcinoma | Graft-Versus-Host Disease | Engraftment Syndrome

United States
H. Lee Moffitt Cancer Center and Research Institute

Completed

In Vivo Treg Expansion and Graft-Versus-Host Disease Prophylaxis

Graft-Versus-Host-Disease

United States
Stanford University

Terminated

Sirolimus & Mycophenolate Mofetil as GvHD Prophylaxis in Myeloablative, Matched Related Donor HCT

Hematologic Diseases | Leukemia | Hodgkin Lymphoma | Acute-graft-versus-host Disease | Non-Hodgkin Lymphoma (NHL)

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Alemtuzumab, Fludarabine Phosphate, and Total-Body Irradiation Followed by Cyclosporine and Mycophenolate Mofetil in Treating Patients Who Are Undergoing Donor Stem Cell Transplant for Hematologic Cancer

Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Juvenile Myelomonocytic Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell... and other conditions

United States, Italy
Merck Sharp & Dohme LLC
AESCA Pharma GmbH

Terminated

Induction of Remission in RA Patients at Low Disease Activity by Additional Infliximab Therapy (Study P04644AM1) (TERMINATED)

Rheumatoid Arthritis
Policlinico Hospital

Completed

Antifungal Prophylaxis in Intensive Care Unit (ICU) Patients

Critical Illness | Surgery | Fungal Prophylaxis | Candida Infection

Italy
Seoul National University Hospital

Completed

Tacrolimus/Methotrexate Versus Cyclosporine/Methotrexate for Prophylaxis of Graft Versus Host Disease

Graft vs Host Disease

Korea, Republic of
Merck Sharp & Dohme LLC

Completed

Prophylaxis Trial in High Risk Allogenic Stem Cell Transplant Recipients With Graft vs. Host Disease

Mycoses
Merck Sharp & Dohme LLC

Completed

Prophylaxis Trial of Posaconazole Versus Standard Azole Therapy for Neutropenic Patients (Study P01899)

Myelodysplastic Syndromes | Neutropenia | Leukemia, Myelocytic, Acute
University Hospital, Brest

Completed

Invasives Aspergillosis in Acute Myeloid Leukemia (IA-AML)

Acute Myeloid Leukemia | Invasive Aspergillosis

France
Affiliated Hospital to Academy of Military Medical...

Unknown

Maraviroc-Based GVHD Prophylaxis in HLA-Unrelated and HLA-Mismatched Related Transplantation

Hematopoietic Stem Cell Transplantation | Graft-versus-host Disease

China
Nantes University Hospital

Completed

Antifungal Prophylaxis With Micafungin After Cord Blood Allogeneic Stem Cell Transplantation (MycaCOORD) (MycaCOORD)

Invasive Fungal Infection

France
Astellas Pharma Korea, Inc.

Completed

Study to Assess the Safety and Efficacy of Tacrolimus (Prograf Capsule/Injection) and Methotrexate (MTX) Combination Therapy for Prevention of Graft Versus Host Disease (GVHD) in Patients Who Received Peripheral Hematopoietic Stem Cell Transplantation From a Sibling Donor

Graft Versus Host Disease

Korea, Republic of
University of California, San Francisco

Withdrawn

Sirolimus Prophylaxis for aGVHD in TME SCID

Severe Combined Immunodeficiency | Stem Cell Transplant | Transplacental Maternal Engraftment

United States
Pfizer

Completed

Voriconazole Versus Itraconazole In Primary Prophylaxis Of Invasive Fungal Infection (IFI) In Subjects With Allogeneic Hematopoietic Stem Cell Transplants (HSCT) (IMPROVIT)

Antifungal Prophylaxis of Invasive Fungal Infections

Canada, Spain, Greece, France, Portugal, United Kingdom, Czech Republic, Egypt, Jordan, Russian Federation, Switzerland, Turkey
Merck Sharp & Dohme LLC

Withdrawn

Evaluation of Treatment and Prophylaxis of Invasive Fungal Infections in Immuncompromised Patients in Austria (Study P05532)(WITHDRAWN)

Mycoses
H. Lee Moffitt Cancer Center and Research Institute

Completed

Graft-Versus-Host Disease (GVHD) Prophylaxis After Allogeneic Peripheral Blood Hematopoietic Cell Transplantation

Acute Graft Versus Host Disease

United States
Gilead Sciences

Completed

PROPHYSOME: Pilot Study on Safety of a Weekly Administration of 10mg/kg of AmBisome® in Antifungal Prophylaxis Treatment of Allogeneic Stem-cell Transplantation and Acute Leukaemia

Leukemia

France
The Affiliated Hospital of the Chinese Academy...

Completed

HLA-mismatched MST vs HLA-matched NST for AML in Intermediate-risk

Acute Myeloid Leukemia

China
Gilead Sciences

Completed

Prevention of Invasive Fungal Infections (IFIs) in Subjects Receiving Chemotherapy for Acute Lymphoblastic Leukemia (AmBiGuard)

Invasive Fungal Disease

United Kingdom
Karolinska Institutet

Completed

Randomized Trial Comparing Sirolimus and Tacrolimus Versus Cyclosporine and Methotrexate as Graft-versus-host Disease (GVHD) Prophylaxis After Allogeneic Stem Cell Transplantation

Survival | Graft-versus-host Disease

Sweden
Universitaire Ziekenhuizen KU Leuven
Institutul Clinic Fundeni

Completed

A New Dosing Regimen for Posaconazole Prophylaxis in Children Based on Body Surface Area

Hematological Malignancy

Belgium, Romania
National Institute of Allergy and Infectious Diseases...

Terminated

Caspofungin Study for Fungal Infections in Adults in Critical Care Settings

Candidiasis

United States
Mesoblast International Sàrl
National Cancer Institute (NCI)

Withdrawn

OTI-010 for Graft-Versus-Host Disease Prophylaxis in Treating Patients Who Are Undergoing Donor Peripheral Stem Cell Transplantation for Hematologic Malignancies

Myelodysplastic Syndromes | Leukemia | Graft Versus Host Disease

United States
Dana-Farber Cancer Institute
Wyeth is now a wholly owned subsidiary of Pfizer; PDL BioPharma, Inc.

Terminated

Sirolimus, Mycophenolate Mofetil and Bortezomib as Graft-Versus-Host Disease (GVHD) Prophylaxis After Reduced Intensity Conditioning (RIC) Hematopoietic Stem Cell Transplantation

Graft-vs-Host Disease

United States
Astellas Pharma Inc

Completed

A Study of Safety and Pharmacokinetics of Repeated Dose of Micafungin as Antifungal Prophylaxis in Children and Adolescents Who Undergo Hematopoietic Stem Cell Transplant

Fungal Infections

United States
National Institute of Allergy and Infectious Diseases...
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

No longer available

B-Lymphocyte Immunotherapy in Islet Transplantation for Initial Islet Graft Failure

Type 1 Diabetes Mellitus

United States
Fundacion SEIMC-GESIDA
Pfizer

Completed

Anidulafungin vs Amphotericin B Safety in High Risk Hepatic Transplant Recipients (AVALTRA)

Fungal Infection | Liver Disease

Spain
Dana-Farber Cancer Institute
Brigham and Women's Hospital

Completed

Tacrolimus and Sirolimus as Prophylaxis After Allogenic Non-myeloablative Peripheral Blood Stem Cell Transplantation

Graft Versus Host Disease | GVHD

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Gemtuzumab Ozogamicin in Treating Young Patients With Newly Diagnosed Acute Myeloid Leukemia Undergoing Remission Induction and Intensification Therapy

Leukemia

United States, Canada, Australia, Puerto Rico, Switzerland
Werner J. Heinz
Merck Sharp & Dohme LLC

Completed

Pharmacokinetic, Safety and Efficacy of Intermittent Application of Caspofungin for Antifungal Prophylaxis (CASPHYLAX)

Fungal Infection

Germany
Bayside Health
Gilead Sciences

Unknown

Intermittent Liposomal Amphotericin B Primary Prophylaxis

Acute Myeloid Leukemia

Australia
Janssen Korea, Ltd., Korea

Completed

The Relationship of Defeverscence and Itraconazole Plasma Level Study in Immunocompromised Participants

Hematologic Neoplasms | Neutropenia | Fever
Zekai Tahir Burak Women's Health Research and Education...

Completed

Comparison of Lactobacillus Reuteri and Nystatin Prophylaxis on Candida Colonization and Infection in Very Low Birth Weight Infants

Very Low Birth Weight Infants

Turkey
University of Chicago
Pfizer

Terminated

Voriconazole as Prophylactic Therapy in Lung Transplant Recipients (VORI)

Infection

United States
M.D. Anderson Cancer Center
Pfizer

Completed

Beta Glucan Assay in Patients Receiving Voriconazole Prophylaxis

Leukemia | Fungal Infection

United States
Azienda Ospedaliera di Padova
Merck Sharp & Dohme LLC

Unknown

Caspofungin as Prophylaxis in High Risk Liver Transplantation Recipients (CPHRLTX)

Mycoses | Fungemia

Italy

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