Search clinical trials for: Extended spectrum beta lactamase producing organisms

Total 17897 results

Hospital Universitari de Bellvitge
Institut d'Investigació Biomèdica de Bellvitge; Instituto de Salud Carlos III

Recruiting

Efficacy of Extended Infusion of β-lactam Antibiotics for the Treatment of Febrile Neutropenia in Hematologic Patients (BEATLE)

Febrile Neutropenia

Spain
UMC Utrecht
National University Hospital, Singapore; Berry Consultants; University of Pittsburgh... and other collaborators

Recruiting

Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia (REMAP-CAP)

Community-acquired Pneumonia, Influenza, COVID-19

United Kingdom, United States, Canada, Australia, Netherlands, Croatia, Germany, Belgium, New Zealand, Ireland, Spain, Japan, Hungary, Colombia, India, Nepal, Pakistan, Portugal, Romania, Saudi Arabia
Pfizer
Allergan

Terminated

Efficacy, Safety, and Tolerability of ATM-AVI in the Treatment of Serious Infection Due to MBL-producing Gram-negative Bacteria

Serious Bacterial Infection

Romania, Taiwan, China, Malaysia, Thailand, Philippines, Argentina, Greece, India, United States, Mexico, Russian Federation
Daniel Benjamin
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care (PTN_POPS)

Heart Failure | Epilepsy | Pain | Pneumonia | Sepsis | Inflammation | Hypertension | Chronic Kidney Diseases | Hemophilia | Schizophrenia | Central Nervous System Infections | Nosocomial Pneumonia | Insomnia | Anxiety | Bipolar Disorder | Neutropenia | Staphylococcal Infections | Bradycardia | Seizures | Urinary Tract Infections | Pulmonary... and other conditions

United States, Canada, United Kingdom, Israel, Singapore
The University of Queensland
Merck Sharp & Dohme LLC

Withdrawn

Ceftolozane-tazobactam Versus Meropenem for ESBL and AmpC-producing Enterobacterales Bloodstream Infection (MERINO III)

Bacteremia Caused by Gram-Negative Bacteria

Spain, Australia, Singapore, Italy, Saudi Arabia
Menzies School of Health Research
University of Malaya; Nanyang Technological University; Griffith University; The... and other collaborators

Active, not recruiting

Hospitalised Pneumonia With Extended Treatment (HOPE) Study (HOPE)

Pneumonia

Australia, Malaysia, New Zealand
Franciscus Gasthuis
Erasmus Medical Center

Completed

Reduction of Intravenous Antibiotics In Neonates (RAIN)

Neonatal Infection | Neonatal SEPSIS

Netherlands
Coordinación de Investigación en Salud, Mexico
Instituto Mexicano del Seguro Social; Hospital Infantil de Mexico Federico... and other collaborators

Completed

Efficacy of Betalactam Antibiotics in Prolonged Infusion Compared to Intermittent in Pediatric Patients With Sepsis

Sepsis

Mexico
Duke University
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Multi-Drug Resistant Organism (MDRO): Study of Highly Resistant Escherichia Coli (SHREC)

E Coli Infection

United States
Ain Shams University

Completed

Extended-infusion of Piperacillin-Tazobactam Versus Intermittent Infusion

Gram-Negative Infections

Egypt
University of South Florida
National Cancer Institute (NCI)

Completed

Lisinopril or Coreg CR® in Reducing Side Effects in Women With Breast Cancer Receiving Trastuzumab

Breast Cancer | Cardiac Toxicity

United States
Fundación Pública Andaluza para la gestión de la...
Spanish Network for Research in Infectious Diseases

Completed

Study on Reduced Antibiotic Treatment vs Broad Spectrum Betalactam in Patients With Bacteremia by Enterobacteriaceae (SIMPLIFY)

Enterobacteriaceae Infections

Spain
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Withdrawn

Fecal Transplant +/- Gut Decontamination in Preventing Acute Graft Versus Host Disease in Patients Given Broad-Spectrum Antibiotics

Graft-versus-host Disease Prevention

United States
Venus Remedies Limited

Completed

CSE-1034 (Ceftriaxone+ Sulbactam+ EDTA) Compared to Meropenem in Complicated Urinary Tract Infections (cUTIs) Caused by ESBL Producing Gram Negative Bacteria (PLEA)

Acute Pyelonephritis | Urinary Tract Infection Complicated

India
Universidad del Norte

Unknown

Piperacillin/Tazobactam Versus Carbapenems in Non-bacteremic UTI Due to -ESBL-producing Enterobacteriaceae (CAPITIS)

Urinary Tract Infections | Enterobacteriaceae Infections | Clinical Trial | Carbapenem | Klebsiella Pneumoniae Infection | Infection Due to ESBL Bacteria | Escherichia Coli Infection | Drug Resistance, Bacterial

Colombia
Centre Hospitalier Universitaire, Amiens

Completed

Study of Adverse Effects Occuring in Patients Receiving an Antibiotic Treatment With Temocillin (Témocilline)

Bacterial Infection With One or More Extended Spectrum Betalactamases Remaining Susceptible to Temocillin

France
Centre Hospitalier Universitaire de Besancon

Unknown

PK/PD of Extended-infusion Meropenem, Piperacillin-tazobactam and Cefepime in the Early Phase of Septic Shock (PAACS)

Septic Shock

France
St. Justine's Hospital

Unknown

Safety and Pharmacokinetics of Piperacillin-tazobactam Extended Infusion in Infants and Children (PIP-TAZO) (PIP-TAZO)

Infection

Canada
Tel-Aviv Sourasky Medical Center

Unknown

Short vs Prolonged Antibiotic Treatment for Hospitalized Hemato-oncology Patients With Febrile Neutropenia (RR)

Fever | Febrile Neutropenia

Israel
National Taiwan University Hospital

Completed

The Prevalence of Extend-Spectrum β-Lactamase (ESBL) Producing Isolates Among Common Enterobacteriaceae in Taiwan

Enterobacteriaceae Infections

Taiwan
Inje University

Completed

The Incidence of Extended-spectrum β-lactamase (ESBL) Klebsiella Pneumonia in Patient on Renal Replacement Therapy

End-stage Renal Disease

Korea, Republic of
Pfizer

Completed

A Single, High-Dose Azithromycin Extended Release (60 mg/kg) Compared With 10 Days of High-Dose Amoxicillin Clavulanate in Children With Ear Infections at High Risk of Persistent/Recurrent Ear Infections

Acute Otitis Media

United States, Costa Rica, Chile, Guatemala, Slovakia, Estonia, Mexico, Russian Federation, Israel, Poland, Argentina, Dominican Republic, Panama
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating Antibiotic Utilization Measures and Control of Extended-Spectrum-Lactamases (ESBLs)

Bacterial Infection
Pfizer

Completed

Zmax Compared to Augmentin in Sinusitis

Sinusitis
Abbott

Completed

Comparative Study of the Safety and Efficacy of Clarithromycin Extended-Release Tablets Versus Amoxicillin-Clavulanate for the Treatment of Acute Bacterial Sinusitis

Acute Bacterial Sinusitis (ABS)

Italy, Spain, Greece, United States, Canada, Poland, Lithuania, Hungary, Romania
Universitas Diponegoro
Dr. Kariadi General Hospital Medical Center

Recruiting

Biomarkers & Infection After Prophylactic Antibiotic in Cardiac Implantable Electronic Device Implantation (BI-PACED)

Heart Block | Biomarkers | Antibiotic Prophylaxis | CIED Related Infection | CIED-related Infections

Indonesia
Clinical Hospital Centre Zagreb

Not yet recruiting

Therapeutic Options for CRAB (TheraCRAB)

Infections, Bacterial | Sepsis Bacterial
University Hospital, Ghent

Recruiting

Pediatric Antibiotic Dosing in Extracorporal Membrane Oxygenation (PADECMO) (PADECMO)

Pharmacokinetics | Vancomycin | Amoxicillin-clavulanate | Piperacillin-tazobactam | Teicoplanin | Meropenem | Ciprofloxacin | Amikacin | Cefazolin

Belgium
Instituto Nacional de Cancerologia de Mexico

Recruiting

Ceftolozane/Tazobactam vs. Piperacillin/Tazobactam for the Treatment of Bacteremia in Hemato-oncological Patients

Hematologic Neoplasms | Neutropenia

Mexico
Lifespan
National Institute on Drug Abuse (NIDA)

Recruiting

Injectable Extended-Release Buprenorphine (XR-B) in a Correctional Setting: Qualitative Interviews

Opioid Use Disorder | Treatment Adherence and Compliance | Criminal Justice

United States
Istanbul University - Cerrahpasa (IUC)

Not yet recruiting

The Effect of Psychoeducation Focused on Reducing Internalized Stigma

Schizophrenia | Treatment Adherence | Stigma, Social

Turkey
Petrovsky National Research Centre of Surgery

Recruiting

Antibacterial Tactics Based on Presepsin Level in Thoracic Aorta Surgery Patients

Thoracic Aortic Aneurysm | Thoracic Aortic Dissection | Cardiac Valve Disease | Aortic Aneurysm and Dissection

Russian Federation
Teva Branded Pharmaceutical Products R&D, Inc.

Recruiting

Open-label Trial Characterizing the PK of 3 SC Olanzapine Extended-release Formulations in Participants With Schizophrenia/Schizoaffective Disorder

Schizophrenia, Schizoaffective Disorder

United States
Hellenic Institute for the Study of Sepsis

Recruiting

Clarithromycin Treatment to Prevent Sepsis Progression in CAP (REACT) (REACT)

Community-acquired Pneumonia

Greece
Otto Helve
University of Helsinki

Not yet recruiting

Autoflor -Lyophilized Capsulated Autological FMT to Restore Gut Microbiome After Treatment With Antibiotics (FMT)

Microbial Colonization | Antibiotic Side Effect

Finland
Nantes University Hospital

Not yet recruiting

Amoxicillin Alone Versus Amoxicillin/Clavulanate for Community-acquired Pneumonia in Patients Aged 65 Years or Older, and Hospitalized in a Non-intensive Care Unit Ward (CAPTAIN)

Community-acquired Pneumonia
Sichuan Provincial People's Hospital

Not yet recruiting

Precise Treatment of Ceftazidime-Avibactam in Patients With CRO Infections Under the Guidance of TDM and PPK Model

ECMO | Carbapenem-Resistant Enterobacteriaceae Infection
Sichuan University

Not yet recruiting

Effect of TEE-guided Non-fluid Limited Combined With Dobutamine on Hepatic Venous Blood Flow Spectrum

Laparoscopic Hepatectomy

China
University Hospital, Strasbourg, France

Recruiting

Interest in Probabilistic Antibiotic Therapy With Broad-spectrum Beta-lactams in Orthopedic Surgery (Prob-ATB)

Joint Infection

France
Assiut University

Not yet recruiting

Prophylactic Antibiotic in Non-complicated Low Risk Lap Cholecystectomy (LC)

Cholecystectomy, Laparoscopic
Scandinavian Critical Care Trials Group

Not yet recruiting

Empirical Meropenem Versus Piperacillin/Tazobactam for Adult Patients With Sepsis (EMPRESS)

Sepsis | Septic Shock

Denmark
Qpex Biopharma, Inc.
Shionogi Inc.; Biomedical Advanced Research and Development Authority

Not yet recruiting

PK & Safety Study of Xeruborbactam Oral Prodrug Combined With Ceftibuten in Participants With Renal Impairment

Bacterial Infections
University Hospital, Rouen

Not yet recruiting

Postoperative Anti-infective Strategy Following Pancreaticoduodenectomy in Patients With Preoperative Biliary Stent (FRENCH24 ANIS)

Pancreaticoduodenectomy | Antibiotherapy
Qpex Biopharma, Inc.
Shionogi Inc.; Biomedical Advanced Research and Development Authority

Recruiting

P1, DDI & MAD PK and Safety Study of Xeruborbactam Oral Prodrug in Combo With Ceftibuten in Healthy Participants

Bacterial Infections

Australia
Shandong University
Shandong Provincial Hospital

Recruiting

Population Pharmacokinetic of Piperacillin/Tazobactam in Maternal and Neonatal Populations

Early-Onset Neonatal Sepsis

China
University Hospital, Lille

Not yet recruiting

Validation of the French Version of the Lithium Knowledge Test (LKT) (LKT)

Patient Treated With Lithium, With Bipolar or Schizo-affective Disorder, Hospitalized in a Psychiatric Ward
Sunshine Coast Hospital and Health Service
The Prince Charles Hospital; Mater

Not yet recruiting

Ceftolozane/Tazobactam Continuous Infusion for Infective Exacerbations of Cystic Fibrosis and Bronchiectasis (CERTAIN)

Bronchiectasis | Cystic Fibrosis | Pseudomonas Aeruginosa | Burkholderia Cepacia Infection
Cairo University

Recruiting

Topical Adrenaline Versus Warm Saline Solution for Minimizing Intraperitoneal Bleeding During Caesarian Delivery for Placenta Previa / Accreta Spectrum ( PAS)

Placenta Accreta | Placenta Previa

Egypt
University Hospital, Ghent
Imec; Research Foundation Flanders

Not yet recruiting

Validation of Betalactam ML Prediction Models - TDMAide (TDMAide)

Infections

Belgium
Helse Stavanger HF
Oslo University Hospital; Haukeland University Hospital; St. Olavs Hospital; Alesund... and other collaborators

Recruiting

Antibiotics, Microbiology and Immunology in Children With Chronic Wet Cough - the AMIC Study (AMIC)

Protracted Bacterial Bronchitis

Norway

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