Search clinical trials for: First-line therapy

Total 51741 results

Genta Incorporated

Unknown

Tesetaxel Plus Capecitabine and Cisplatin in Advanced Gastric Cancer

Gastric Carcinoma

Korea, Republic of
University of Virginia
American College of Gastroenterology

Unknown

Pravastatin Therapy in Patients With Active Crohn's Disease: A Pilot Study

Crohn's Disease

United States
Chronic Lymphocytic Leukemia Research Consortium
Celgene Corporation

Unknown

Multi-center Trial of Revlimid® and Rituximab, for First-Line Treatment of Chronic Lymphocytic Leukemia (CLL)

Chronic Lymphocytic Leukemia | CLL | Untreated | First-Line | Front-line | Initial Therapy

United States
Korean Cancer Study Group

Unknown

S-1 and Irinotecan Combination Chemotherapy for Advanced Gastric Cancer

Gastric Cancer

Korea, Republic of
UPECLIN HC FM Botucatu Unesp

Unknown

Lopinavir/Ritonavir or Efavirenz as First-line Antiretroviral Therapy

HIV Infections

Brazil
Nanfang Hospital, Southern Medical University

Not yet recruiting

Long-term Outcomes of Duodenal Adenocarcinoma From a Large Cohort

Gastrointestinal Disease
Shandong Cancer Hospital and Institute

Recruiting

WASPE Sleep Adjustment for Children Aged 0-4 Years Undergoing Radiation Therapy

Pediatric Cancer

China
Miami Cancer Research Center, Inc.

Recruiting

I-124 PET/CT Imaging and Dosimetry for RAI-Naïve or Refractory Thyroid Cancer

Thyroid Cancer | RAI-Refractory Thyroid Cancer

United States
Fresenius Medical Care Deutschland GmbH
Winicker Norimed GmbH

Not yet recruiting

Influence of Variable Inflow Volume, Dwell Duration and Glucose Concentration on Ultrafiltration Volume in APD Patients (pPD)

Chronic Kidney Diseases | Renal Failure
Takeda

Not yet recruiting

A Study to Learn About the Safety of Vedolizumab and How Well it Works in Children and Teenagers With Active Chronic Pouchitis

Pouchitis

Belgium, Spain, Czechia, Italy, Israel, Croatia, Greece, Poland
University of Sydney
Woke Pharmaceuticals

Not yet recruiting

A Multi-centre, Double-blinded, Placebo-controlled, Randomised, Phase II Clinical Trial for Psilocybin-assisted Therapy for Alcohol Use Disorder

Depression | Alcohol Dependence | Anxiety | Alcohol Use Disorder
William Beaumont Hospitals

Recruiting

HYPOFRACTIONATED REGIONAL NODAL IRRADIATION IN BREAST CANCER

Breast Cancer

United States
Lei Liu

Not yet recruiting

A Phase II Study of Neoadjuvant Immunotherapy in Combination With Chemotherapy in Locally Advanced Head and Neck Squamous Cell Carcinoma

Head and Neck Squamous Cell Carcinoma
University Hospital, Angers

Not yet recruiting

Gene Therapy Development and Validation for Huntington's Disease Fibro TG-HD (FibroTG-HD)

Huntington Disease

France
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Efficacy and Safety of Bezafibrate 400 mg and Bezafibrate 200 mg as Adjunctive Treatments in Patients With Primary Biliary Cholangitis and Non-optimal Biochemical Response to Ursodeoxycholic Acid Therapy (BEZURSO 2)

BPC | Non Optimal Response to UDCA

France
Kirsehir Ahi Evran Universitesi

Recruiting

Spine of Caregivers of Children With Cerebral Palsy

Cerebral Palsy | Spine Deformity

Turkey
Osaka University
Japan Agency for Medical Research and Development

Recruiting

Clinical Trial of Targeted Alpha Therapy for Prostate Cancer (Alpha-PS1)

Prostate Cancer

Japan
University of Michigan Rogel Cancer Center

Not yet recruiting

Self-Administered Relaxing Acupressure to Reduce Fatigue in Adolescent and Young Adult Cancer Survivors

Malignant Solid Neoplasm | Hematopoietic and Lymphatic System Neoplasm

United States
Ain Shams University

Recruiting

Clinical Outcome of Vinpocetine in Diabetic Nephropathy

Diabetic Kidney Disease | Diabetic Nephropathies

Egypt
NYU Langone Health

Not yet recruiting

Efficacy Of Combined Nebulized Hypertonic Saline and Chest Percussion Therapy in Acute Viral Bronchiolitis

Acute Bronchiolitis

United States
Uppsala University

Not yet recruiting

A Metacognitive Group Therapy of Depression and Anxiety in Youth With Autism

Anxiety Depression

Sweden
Medical University of South Carolina
National Institute on Drug Abuse (NIDA)

Not yet recruiting

ACTION: Trial of Adding Buprenorphine, CBT, and TMS to Improve Outcomes of Long-Term Opioid Therapy for Chronic Pain (ACTION)

Chronic Pain | Opioid Withdrawal

United States
Accelerated Cure Project for Multiple Sclerosis
Charite University, Berlin, Germany; United States Department of Defense; US... and other collaborators

Not yet recruiting

Confirmatory Trial for Alleviating Fatigue in Multiple Sclerosis (CAFE-MS)

Multiple Sclerosis | Fatigue
University of Palermo

Recruiting

Effectiveness of Extracorporeal Shockwave Therapy and Nutraceutical Supplementation in the Treatment of Epicondylitis: a Clinical Trial

Tennis Elbow | Epicondylitis, Lateral | Epicondylitis of the Elbow

Italy
University of Illinois at Chicago

Not yet recruiting

BRE-10: Biomarker Optimization of Neoadjuvant Therapy in Breast Cancer (BRE-10)

Breast Cancer | HER2-positive Breast Cancer
Foundation University Islamabad

Recruiting

Effects of Intra Muscular Electrotherapy Combined With Manipulative Therapy in Patients With Sacral Torsion

Sacroiliac Joint Dysfunction

Pakistan
Fondazione Italiana Linfomi - ETS

Not yet recruiting

Retrospective-prospective Study to Evaluate Treatment Management and Outcomes of Patients With Waldenström's Macroglobulinemia (WM) Treated in Italy According to the Zanubrutinib (Brukinsa®) Compassionate Use Program (CUP) and in Common Practice Following Commercial Approval.

Waldenström's Macroglobulinemia (WM)

Italy
Matthew R. Hoffman

Not yet recruiting

Characterizing the Impact of Presbyphonia on Social Interaction

Presbyphonia
Astellas Pharma Global Development, Inc.

Not yet recruiting

A Study to Confirm if Fezolinetant Helps Reduce Hot Flashes in Women With Breast Cancer Who Are Having Hormone Therapy

Hot Flashes
Regina Elena Cancer Institute

Recruiting

Low Intensity Shock Wave Therapy in the Rehabilitation Treatment of Erectile Dysfunction After Robotic Radical Prostatectomy.

Erectile Dysfunction

Italy
ITM Solucin GmbH

Not yet recruiting

Phase I Trial to Determine the Dose and Evaluate the PK of Lutetium Lu 177 Edotreotide Therapy in Pediatric Participants With SSTR-positive Tumors (KinLET)

Lymphoma | CNS Tumor | Solid Tumor, Childhood | Somatostatin Receptor Positive | NET
Northwestern University

Not yet recruiting

Behavioral Treatment for Nightmares in REM Sleep Behavior Disorder

REM Sleep Behavior Disorder | Nightmare | Nightmare Disorder With Associated Other Sleep Disorder

United States
Centre Henri Becquerel

Not yet recruiting

Contribution of the VERITON-CT Camera in Prostate Bone Radiostereotaxy (VERIOS)

Prostatic Cancer

France
Virginia Commonwealth University

Not yet recruiting

CBT-I in Primary Brain Tumor Patients: Phase IIc Randomized Feasibility Pilot Trial (CBT-I in PBT)

Glioblastoma | Astrocytoma | Oligodendroglioma | Meningioma | Primary Brain Tumor | Primary Central Nervous System (CNS) Lymphoma

United States
Instituto de Investigación Biomédica de Salamanca
Carlos III Health Institute

Recruiting

Study of the Hematopoietic Niche and the Role of Inflammation in the Pathophysiology of Cytopenias After CAR-T Cell Therapy: Potential of Therapies Directed to Repair the Bone Marrow Microenvironment

Diffuse Large B Cell Lymphoma

Spain
Taif University

Not yet recruiting

Effects of Lymph Drainage on Patients With Axillary Web Syndrome

Movement Disorders
Novartis Pharmaceuticals

Not yet recruiting

A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE) (SPARKLE)

Sickle Cell Disease
Main Line Health
Pfizer; Sumitomo Pharma America, Inc.

Not yet recruiting

The Effect of Medical Management Following Excisional Surgery for Endometriosis: A Randomized Controlled Trial

Endometriosis

United States
University of Alabama at Birmingham

Not yet recruiting

Role of Combination Therapy in Women With Refractory Overactive Bladder

Overactive Bladder Syndrome
Clinical Hospital Centre Zagreb

Not yet recruiting

Therapeutic Options for CRAB (TheraCRAB)

Infections, Bacterial | Sepsis Bacterial
Indonesia University

Recruiting

The Role of Thread Embedding Acupuncture for Pain and Quality of Life in Endometriosis Patients

Endometriosis-related Pain

Indonesia
University Hospital, Bordeaux
Baxter Healthcare Corporation

Not yet recruiting

Immunothrombosis With Septic Shock Undergoing Renal Replacement Therapy With the OXIRIS Membrane (PLAQSIRIS)

Sepsis

France
Gustave Roussy, Cancer Campus, Grand Paris

Recruiting

Lymphocyte Support to SBRT in Patients With Oligo-metastatic Solid Cancer (LySATRA)

Solid Tumor, Adult | Oligometastatic Disease

France
Dana-Farber Cancer Institute
Johns Hopkins University; Translational Breast Cancer Research Consortium

Not yet recruiting

The SAPPHO Study: A Single-Arm, Phase II Study of Sequential Therapy With Curative Intent in de Novo HER2+ Metastatic Breast Cancer

Breast Cancer | HER2-positive Breast Cancer | Stage IV Breast Cancer | Breast Cancer Female | Breast Cancer Metastatic | Estrogen Receptor-positive Breast Cancer

United States
Foundation University Islamabad

Recruiting

Effects of Sustained Natural Apophyseal Glides Combined With Kinesiotaping in Patients With Chronic Mechanical Neck Pain: A Randomised Controlled Trial

Neck Pain

Pakistan
Tianjin Medical University Cancer Institute and...
Kingbio Medical (Beijing) Co., Ltd.

Not yet recruiting

Clinical Treatment of Refractory Breast Cancer Based on Organoid Drug Sensitivity Results

Refractory Breast Cancer
Foundation University Islamabad

Recruiting

Comparison of Effectiveness Between Active Release Technique and Hold Relax Technique in Patients With Piriformis Syndrome

Piriformis Syndrome

Pakistan
Fondation Ophtalmologique Adolphe de Rothschild

Not yet recruiting

Glenzocimab in Anterior Stroke With Large Ischemic Core Eligible for Endovascular Therapy (GALICE)

Acute Ischemic Stroke
Nigde Omer Halisdemir University
Selcuk University

Not yet recruiting

The Effectiveness of Two Different Methods in Heel Blood Collection

Pain | Infant Behavior
Foundation University Islamabad

Recruiting

"Effects of Passive Static Stretching of 30 Seconds Versus 60 Seconds on the Hamstring Flexibility in Adults With Hamstring Tightness.

Hamstring Flexibility

Pakistan

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