Search clinical trials for: Focal onset seizures

Total 4374 results

Beth Israel Deaconess Medical Center
AbbVie

Recruiting

BOTOX Effects on Seizure Severity and Susceptibility

Drug-resistant Focal Seizure

United States
Ohio State University

Not yet recruiting

The Impact of Focused Ultrasound Thalamotomy of the Anterior Nucleus for Focal-Onset Epilepsy on Anxiety

Anxiety | Medication-refractory Focal-onset Epilepsy

United States
NYU Langone Health

Not yet recruiting

Efficacy of Intersectional Short Pulse Stimulation for Terminating Seizures

Seizures | Focal Epilepsy
Neuroelectrics Corporation

Recruiting

Pivotal-Safety and Therapeutic Measures of tDCS in Patients With Refractory Focal Epilepsy

Epilepsy | Seizures | Refractory Epilepsy | Epilepsy, Tonic-Clonic | Epilepsy in Children | Seizures, Focal | Focal Seizure

Spain, United States, France, Belgium
Institut National de la Santé Et de la Recherche...

Not yet recruiting

Multi-level Approach of Brain Activity Using Intracranial Electrodes in Epileptic Patients (EpiMicro)

Cognitive Function | Focal Epilepsy | Neurophysiology | Electrodes, Implanted
Institut National de la Santé Et de la Recherche...
France Alzheimer

Not yet recruiting

MECHANISMS OF NEURONAL RESILIENCE IN ALZHEIMER'S DISEASE AND ITS FOCAL VARIANTS: A PET/MR STUDY (PET-AL)

Alzheimer Disease, Early Onset | Posterior Cortical Atrophy

France
ProgenaBiome

Recruiting

A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Alzheimer's Disease

Alzheimer Disease | Alzheimer Disease, Early Onset | Alzheimer Disease, Late Onset | Alzheimer Disease 1 | Alzheimer Disease 2 | Alzheimer Disease 3 | Alzheimer Disease 4 | Alzheimer Disease 7 | Alzheimer Disease 17 | Alzheimer Disease 5 | Alzheimer Disease 6 | Alzheimer Disease 8 | Alzheimer Disease 10 | Alzheimer... and other conditions

United States
Eisai Inc.

Recruiting

A Study to Evaluate Efficacy and Safety of Perampanel Administered as an Adjunctive Therapy in Pediatric Participants With Childhood Epilepsy

Partial-onset Seizures | Pediatric Epileptic Syndrome

United States, Spain, France, Belgium, Czechia, Denmark, Germany
Children's Hospital of Fudan University

Recruiting

A Cohort Study on the Prognosis of Neonatal KCNQ2 Gene-associated Epileptic Encephalopathy

Seizures | Seizure Disorder | Epileptic Encephalopathy | Seizures, Generalized | Seizure Newborn | Epileptic Encephalopathy, Neonatal-onset | Epileptic Encephalopathy, Infant-onset | KCNQ2

China
Beijing Children's Hospital
Hopital Universitaire Robert-Debre; Shandong University; Rennes University Hospital

Recruiting

Population Pharmacokinetics of Anti-tuberculosis Drugs in Children With Tuberculosis

Tuberculosis

China
Fondation Ophtalmologique Adolphe de Rothschild

Recruiting

Impact of Thermocoagulation During Invasive EEG Monitoring in Children With Focal Drug-resistant Epilepsies (COAG)

Epilepsy

France
Boston Children's Hospital

Recruiting

Genetics of Epilepsy and Related Disorders

Epilepsy | Dravet Syndrome | Infantile Spasms | Epileptic Encephalopathy | Ohtahara Syndrome | Early Myoclonic Epileptic Encephalopathy | PCDH19-related Epilepsy and Related Conditions | KCNQ2-Related Epileptic Encephalopathy | Epilepsy of Infancy With Migrating Focal Seizures (Disorder)

United States
Eisai Inc.

Available

An Extended Access Program (EAP) for Perampanel

Lennox Gastaut Syndrome | Primary Generalized Tonic-Clonic or Partial Onset Seizures

Belgium, Chile, Estonia, Hungary, Latvia, Lithuania, Poland, Spain, Czechia, Serbia
SK Life Science, Inc.

Completed

Safety and Pharmacokinetic Study of YKP3089 as Adjunctive Therapy in Subjects With Partial Onset Seizures

Partial Epilepsy

United States, Spain, Korea, Republic of, Serbia, Germany, Bulgaria, Argentina, Australia, Chile, Czechia, Hungary, Mexico, Poland, Russian Federation, Sweden, Thailand, Ukraine
UCB S.A. - Pharma Sector

Completed

Study With Seletracetam (Ucb 44212) in Adult Subjects (18 to 65 Years) With Partial Onset Seizures

Epilepsy, Partial

United States
RTI International
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Enrolling by invitation

Early Check: Expanded Screening in Newborns

Primary Hyperoxaluria Type 3 | Diabetes Mellitus | Hemophilia A | Hemophilia B | Hereditary Fructose Intolerance | Cystic Fibrosis | Factor VII Deficiency | Phenylketonurias | Sickle Cell Disease | Dravet Syndrome | Duchenne Muscular Dystrophy | Prader-Willi Syndrome | Fragile X Syndrome | Chronic Granulomatous Disease and other conditions

United States
Xenon Pharmaceuticals Inc.
Worldwide Clinical Trials

Enrolling by invitation

An Open-label Study of XEN1101 in Epilepsy (X-TOLE4)

Focal Epilepsy | Tonic-Clonic Seizures

Spain, United States, Canada, Poland
Balikesir University

Completed

What Are the Determinant Factors of Ceasing Anti-seizure Medication in Infants With Neonatal Seizures?

Neonatal Seizure

Turkey
Assistance Publique - Hôpitaux de Paris

Terminated

Perampanel in Focal Status Epilepticus (PEPSI)

Epilepticus; Status, Focal Motor

France
UCB Pharma SA

Completed

Open-label Long-term Study of Adjunctive Brivaracetam in Pediatric Subjects With Epilepsy

Epilepsy

United States, Belgium, Czechia, France, Germany, Hungary, Ireland, Italy, Mexico, Poland, Spain, United Kingdom
King's College London
King's College Hospital NHS Trust

Completed

Subcutaneous EEG: Forecasting of Epileptic Seizures (SUBER)

Epilepsies, Focal

United Kingdom
SK Life Science, Inc.

Active, not recruiting

Randomized, Double-blind Study to Evaluate Efficacy and Safety of Cenobamate Adjunctive Therapy in POS

Partial Seizure | Focal Seizure

China, Japan, Korea, Republic of
State Budgetary Healthcare Institution, National...

Enrolling by invitation

Thermocoagulation in Drug Resistant Focal Epilepsy

Epilepsy | Epilepsies, Partial | Epilepsy Intractable | Seizures, Focal

Russian Federation
Epilepsy Foundation of America
UCB Biopharma S.P.R.L.; The Epilepsy Study Consortium

Completed

Human Epilepsy Project 2: Resistant Focal Seizures Study (HEP2)

Brain Diseases | Central Nervous System Diseases | Nervous System Diseases | Epilepsy | Biomarkers

United States
UCB Pharma SA

Completed

Study With Subjects 18-65 Years Old With Partial Onset Seizures Who Are Currently Taking Levetiracetam

Epilepsy, Partial

Canada, United States
Daniel Benjamin
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care (PTN_POPS)

Heart Failure | Epilepsy | Pain | Pneumonia | Sepsis | Inflammation | Hypertension | Chronic Kidney Diseases | Hemophilia | Schizophrenia | Central Nervous System Infections | Nosocomial Pneumonia | Insomnia | Anxiety | Bipolar Disorder | Neutropenia | Staphylococcal Infections | Bradycardia | Seizures | Urinary Tract Infections | Pulmonary... and other conditions

United States, Canada, United Kingdom, Israel, Singapore
Engrail Therapeutics INC

Withdrawn

ENACT: A Study of ENX-101 as Adjunctive Treatment in Patients With Focal Seizures (ENACT)

Focal Epilepsy

United States
Marinus Pharmaceuticals

Terminated

A Two-year Open-label Extension Study of Ganaxolone in Patients With Drug-resistant Partial-onset Seizures

Drug Resistant Partial Onset Seizure

United States
Mayo Clinic
National Cancer Institute (NCI)

Terminated

Perampanel for the Reduction of Seizure Frequency in Patients With High-grade Glioma and Focal Epilepsy

Malignant Glioma | WHO Grade 3 Glioma | Intractable Epilepsy | Seizure Disorder | WHO Grade 2 Glioma

United States
Eisai Inc.

Completed

A Post-marketing Observational Study Of The Use Of Zonisamide (ZNS) in the Adjunctive Treatment Of Adult Patients With Partial Onset Seizures (Study E2090-E044-410) (ZOOM)

Partial Onset Seizures

Germany, Sweden, Norway, Austria, Denmark
UCB Biopharma S.P.R.L.
Parexel

Completed

A Clinical Study to Investigate the Long-term Use of Lacosamide as Monotherapy in Subjects Who Completed Study SP0994

Epilepsy

Bulgaria, Finland, France, Germany, Japan, Korea, Republic of, Latvia, Mexico, Philippines, Poland, Romania, Russian Federation, Sweden, Switzerland, Ukraine
Marinus Pharmaceuticals

Completed

A Randomized, Controlled Trial of Ganaxolone in Adult Uncontrolled Partial-Onset Seizures

Partial Epilepsy | Catamenial Epilepsy

United States
Marinus Pharmaceuticals

Completed

Phase 3 Study of Adjunctive Ganaxolone in Adults With Drug-resistant Partial Onset Seizures and Open-label Extension

Drug Resistant Partial Onset Seizure

United States, Australia, Russian Federation, Bulgaria, Germany, Poland
Eisai Limited

Completed

A Study to Investigate Dosage, Effectiveness, and Safety of Perampanel When Used as First Add-on Therapy in Participants >=12 Years With Partial Onset Seizures With or Without Secondary Generalization or With Primary Generalized Tonic-Clonic Seizures Associated With Idiopathic Generalized Epilepsy

Idiopathic Generalized Epilepsy | Partial Onset Seizures | Generalised Tonic-Clonic Seizures

France, Spain, Italy, Denmark, Germany, Portugal, Russian Federation
Marinus Pharmaceuticals

Completed

Open-label Extension to Protocol 1042-0600

Epilepsies, Partial

United States
Jazz Pharmaceuticals

Completed

A Study of GWP42006 in People With Focal Seizures - Part B

Epilepsy | Focal Seizures

Italy, Poland, United Kingdom, Spain, Hungary, Czechia
Jazz Pharmaceuticals

Completed

A Study of GWP42006 in People With Focal Seizures - Part A

Epilepsy | Focal Seizures

United Kingdom, Spain, Czechia
Jie Liu

Completed

The Etiology of New-onset Status Epilepticus

Status Epilepticus

China
Eisai Inc.

Completed

Perampanel as Adjunctive Therapy in Pediatrics With Partial Onset Seizures or Primary Generalized Tonic Clonic Seizures

Partial-Onset or Primary Generalized Tonic-Clonic Seizures

Canada, France, Italy, Korea, Republic of, Spain, United States, Belgium, Czechia, Hungary, Japan, Latvia, Poland
UCB BIOSCIENCES, Inc.
UCB Biopharma SRL

Completed

A Clinical Study to Investigate the Efficacy and Safety of Lacosamide as an Add on Therapy in Children With Epilepsy With Partial-onset Seizures

Epilepsy

United States, Argentina, Australia, Belgium, Brazil, Bulgaria, China, Colombia, Croatia, Czechia, Estonia, France, Georgia, Greece, Hungary, Israel, Italy, Korea, Republic of, Latvia, Lithuania, Mexico, Moldova, Republic of, Monten... and more
Supernus Pharmaceuticals, Inc.

Active, not recruiting

BIS-001-ER for the Treatment of Adult Focal Impaired Awareness Seizures (FIAS)

Focal Impaired Awareness Seizures

Australia
Eisai Co., Ltd.

Completed

Investigation of the Clinical Safety and Efficacy of Long-term Treatment With Fycompa Tablets in Adolescence Epilepsy Patients With Partial-onset Seizures (With or Without Secondary Generalized Seizures) or Primary Generalized Tonic-clonic Seizures (FYC02T)

Partial Seizures (With or Without Secondary Generalized Seizures) | Primary Generalized Tonic-clonic Seizures

Japan
UCB Pharma

Completed

Brivaracetam Efficacy and Safety Study in Subjects With Partial Onset Seizures (BRITE)

Epilepsy

United States, Czechia, Germany, Poland, Austria, Belgium, Brazil, Bulgaria, Canada, Estonia, Finland, France, Hong Kong, Hungary, India, Italy, Japan, Korea, Republic of, Latvia, Lithuania, Mexico, Netherlands, Puerto Rico, Russian Federation and more
UCB Pharma

Completed

Double-blind, Randomized Study Evaluating the Efficacy and Safety of Brivaracetam in Adults With Partial Onset Seizures

Epilepsy

United States, Australia, Canada, Brazil, Mexico
UCB Pharma SA

Completed

Double-blind, Randomized Study Evaluating the Efficacy and Safety of Brivaracetam in Adults With Partial Onset Seizures

Epilepsy

Belgium, Finland, France, Germany, Hungary, India, Italy, Netherlands, Poland, Spain, Switzerland, United Kingdom
Eisai Inc.

Completed

Study to Evaluate the Efficacy and Safety of Perampanel as Monotherapy or First Adjunctive Therapy in Subjects With Partial Onset Seizures With or Without Secondarily Generalized Seizures or With Primary Generalized Tonic-Clonic Seizures

Partial Onset Seizures | Primary Generalized Tonic-Clonic Seizures | Secondarily Generalized Seizures

United States
SK Life Science, Inc.

Completed

A Double-Blind, Randomized, Placebo-Controlled, Phase 2 Trial of YKP3089 as Adjunctive Therapy in Subjects With Partial Onset Seizures

Partial Epilepsy

Australia, United States, Korea, Republic of, Germany, Hungary, Serbia, Bulgaria, Czechia, France, Israel, Poland, Romania, Spain, Thailand, Ukraine
SK Life Science, Inc.

Completed

Efficacy and Safety of YKP3089 in Subjects With Treatment Resistant Partial Onset Seizures

Partial Epilepsy

Korea, Republic of, United States, India, Poland
Eisai Co., Ltd.

Completed

Investigation of the Clinical Safety and Efficacy of Long-term Treatment With Fycompa Tablets in Adult Epilepsy Patients With Partial-onset Seizures (With or Without Secondary Generalized Seizures) or Primary Generalized Tonic-clonic Seizures (FYC01S)

Partial Seizures (With or Without Secondary Generalized Seizures) | Primary Generalized Tonic-clonic Seizures

Japan
SK Life Science, Inc.

Approved for marketing

Cenobamate Expanded Access Program (EAP)

Partial Epilepsy

Search clinical trials for: Focal onset seizures

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Belgium

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations