Search clinical trials for: General Safety

Total 275453 results

Fujian Shengdi Pharmaceutical Co., Ltd.

Not yet recruiting

Safety, Tolerability, and Preliminary Efficacy of HRS-7450 Injection in the Treatment of Acute Ischemic Stroke: a Multi-center, Randomized, Double-blind, Double-dummy, Placebo-controlled Clinical Trial

Acute Ischemic Stroke

China
Xuanwu Hospital, Beijing

Not yet recruiting

Efficacy and Safety Evaluation of Hyperthermic Baths in the Treatment of Seizures in Children With CDKL5 Deficiency

CDKL5 Deficiency Disorder

China
Shanghai Zhongshan Hospital

Not yet recruiting

Efficacy and Safety of Oxycodone Hydrochloride for Long-term Analgesia in ICU Patients

Analgesia | Mechanical Ventilation | Remifentanil | Postoperative | Oxycodone

China
Penumbra Inc.

Recruiting

Post Market Surveillance to Evaluate the Efficacy and Safety of the INDIGO Aspiration System in Japan (JapanIndigoPMS)

Arterial Occlusion Mesenteric Artery Superior | Acute Limb Ischemia | Acute DVT of Lower Extremity

United States
Insel Gruppe AG, University Hospital Bern

Not yet recruiting

The Effect of Acute High Altitude Exposure on Rescuer Performance and Patient Care

Risk Reduction | Hypobaric Hypoxia | High Altitude

Switzerland
Neudive Inc.

Not yet recruiting

To Evaluate the Efficacy and Safety of 'NDTx-01' in Patients With ASD or SCD

Autism Spectrum Disorder | Social Communication Disorder
Ipsen

Not yet recruiting

A Study Observing Everyday Effectiveness and Safety of the Drug Elafibranor in Participants With Primary Biliary Cholangitis Who Are Receiving Ongoing Treatment (ELFINITY)

Primary Biliary Cholangitis
LEO Pharma

Not yet recruiting

A Study to Evaluate Efficacy, Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of a Single Dose of LEO 158968

Joint Pain | Gout Flares | Joint Inflammation
Scholar Rock, Inc.

Recruiting

Efficacy and Safety of Apitegromab for the Treatment of Adults Who Are Overweight or Obese (EMBRAZE)

Overweight and Obesity

United States
Mohammad Farris Iman Leong Bin Abdullah

Not yet recruiting

Efficacy and Safety of Low-dose Laser Acupuncture on Treating Insomnia Associated With Major Depressive Disorder

Insomnia | Major Depressive Disorder
Takeda

Not yet recruiting

A Study to Learn About the Safety of Vedolizumab and How Well it Works in Children and Teenagers With Active Chronic Pouchitis

Pouchitis

Belgium, Spain, Czechia, Italy, Israel, Croatia, Greece, Poland
Sanofi

Recruiting

A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Adult Participants With Severe Alopecia Areata

Alopecia Areata

United States, Canada
Alcon Research

Not yet recruiting

Study of Safety and Performance of a Novel Ocular Lubricant in Subjects With Dry Eye Disease

Dry Eye Disease

United States
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Efficacy and Safety of Bezafibrate 400 mg and Bezafibrate 200 mg as Adjunctive Treatments in Patients With Primary Biliary Cholangitis and Non-optimal Biochemical Response to Ursodeoxycholic Acid Therapy (BEZURSO 2)

BPC | Non Optimal Response to UDCA

France
Biohaven Therapeutics Ltd.

Not yet recruiting

Long-term Safety and Tolerability of BHV-7000

Focal Epilepsy
National Institute of Allergy and Infectious Diseases...
KBio Inc

Not yet recruiting

Phase 1, Randomized, Double-Blind, Placebo-controlled Study to Evaluate the Safety and Tolerability of an Enterovirus D68-specific Monoclonal Antibody in Healthy Adults

Enterovirus Infection

United States
argenx

Not yet recruiting

A Safety and Efficacy Study of ARGX-119 in Adult Patients With Amyotrophic Lateral Sclerosis (ALS) (ReALiSe)

Amyotrophic Lateral Sclerosis
NovoBliss Research Pvt Ltd
Winnox Cosmeceutics Sdn. Bhd

Not yet recruiting

A Clinical Study to Determine the Safety and Efficacy of Bio-Ray Knee Guard in Panelists With Varicose Vein and Knee Pain.

Varicose Veins With Self-declared Knee Pain
Guangdong Hengrui Pharmaceutical Co., Ltd

Not yet recruiting

A Study to Evaluate the Long-term Safety, Pharmacodynamics and Efficacy of SHR-1703 in Eosinophilic Asthma Patients

Eosinophilic Asthma Patients
Guangzhou Patronus Biotech Co., Ltd.
Yantai Patronus Biotech Co., Ltd.

Not yet recruiting

A Safety and Immunogenicity Trial of a Respiratory Syncytial Virus Vaccine, LYB005 in Healthy Adults

Respiratory Syncytial Virus (RSV) | RSV Infection
Mohd Zulfakar Mazlan, MBBS

Recruiting

To Compare the Efficacy and Safety of Using oXiris and M100 During CRRT

Pneumonia | AKI - Acute Kidney Injury

Malaysia
Siriraj Hospital

Recruiting

The Efficacy and Safety of Platelet-rich Fibrin and Platelet Rich Plasma in Female Pattern Hair Loss Patients (PRF)

Platelet-rich Fibrin | Platelet-Rich Plasma | Female Pattern Hair Loss

Thailand
Fujian Medical University Union Hospital

Recruiting

Multicenter Clinical Trial on the Effectiveness and Safety of Instillation of BCG and Alternative BCG Protocols for Intermediate and High-risk Non-muscle Invasive Bladder Cancer

Urinary Bladder Neoplasms | Treatment Outcome | Neoplasm Recurrence, Local | Multicenter Study | Immunotherapy, Active | BCG Vaccine

China
Sinovac Biotech Co., Ltd

Not yet recruiting

Booster Dose of sIPV Co-administered With MMR and HepA-I.

Poliomyelitis

China
Nuwacell Biotechnologies Co., Ltd.
Beijing Friendship Hospital

Not yet recruiting

A Trial to Evaluate the Safety and Efficacy of NCR300 in Preventing Recurrence of Acute Myeloid Leukemia（AML) After Transplantation

Acute Myeloid Leukemia
Sun Yat-sen University

Recruiting

Fruquintinib With or Without HAI-FOLFOX for Refractory Colorectal Cancer

Colorectal Cancer

China
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Ultrasound-Guided Curved Needle Thread Carpal Tunnel Release: Efficacy and Safety of a Single-Center, Single-Arm Clinical Trial

Carpal Tunnel Syndrome

China
Arthrosi Therapeutics

Recruiting

Phase 3 Evaluation of Efficacy and Safety of AR882 in Gout Patients

Hyperuricemia | Gout | Arthritis, Gouty | Gout Chronic

United States, Australia, New Zealand
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Not yet recruiting

Long-term Safety and Efficacy of TQH2722 Injection in the Treatment of Chronic Sinusitis With or Without Nasal Polyps

Chronic Rhinosinusitis

China
Novartis Pharmaceuticals

Not yet recruiting

A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE) (SPARKLE)

Sickle Cell Disease
Nuritas Ltd

Recruiting

A Study to Determine the Safety and Tolerability of a Range of Doses of PeptiControl in Pre-diabetic Individuals

Overweight | Pre Diabetes

India
Onconic Therapeutics Inc.

Not yet recruiting

Study to Evaluate the Efficacy and Safety of JP-1366 in the Prevention of NSAIDs-Induced Peptic Ulcers

Peptic Ulcer

Korea, Republic of
Heart Rhythm Clinical and Research Solutions, LLC
Boston Scientific Corporation

Recruiting

Safety and Efficacy of Workflows of High Volume Single Operators in a LAAO Device Implant Procedural Day

Atrial Fibrillation

United States
Beijing Tongren Hospital
The First Affiliated Hospital with Nanjing Medical University

Not yet recruiting

Efficacy and Safety of Sugammadex in Thoracoscopy Thymectomy for Chinese Adults With Myasthenia Gravis

Reversal of Neuromuscular Blockade

China
Seoul National University Hospital

Not yet recruiting

Verification of the Efficacy/Safety of the Mixed Drug Injectable Delivery Vehicle for Treating Intractable Hearing Loss

Hearing Loss, Sensorineural | Hearing Loss, Sudden | Intratympanic Injection
argenx

Not yet recruiting

A Phase 1b Study to Investigate Safety and Tolerability of ARGX-119 in Adult Participants With DOK7-Congenital Myasthenic Syndromes (CMS)

Congenital Myasthenic Syndrome
ENTire Medical Ltd.

Recruiting

Efficacy And Safety of An IRE System For Treatment of Inferior Turbinate Hypertrophy

Nasal Obstruction | Inferior Turbinate Hypertrophy | Turbinate; Hypertrophy Mucous Membrane

Israel, Lithuania
Wuhan Union Hospital, China

Recruiting

Efficacy and Safety of Ganciclovir Capsules in the Treatment of Refractory Moderate-to-severe Allergic Rhinitis

Rhinitis, Allergic

China
Istituto Clinico Humanitas

Not yet recruiting

Efficacy, Safety and Recurrence After Cold-EMR Plus APC for Large Colonic Lesions (EMR+APC)

Colonic Disease

Italy
Hanlim Pharm. Co., Ltd.

Recruiting

Study to Evaluate Efficacy and Safety of Bronpass Tab. in Patients With Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease

Korea, Republic of
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Not yet recruiting

The Efficacy and Safety of Nelarabine Injection in Patients With T-lymphoblastic Leukemia and T-lymphoblastic Lymphoma

T-lymphoblastic Lymphoma | T-lymphoblastic Leukemia

China
Massachusetts General Hospital
Patient-Centered Outcomes Research Institute

Not yet recruiting

Sequential Multiple Assignment Randomized Trial for Bipolar Depression (SMART-BD)

Depression | Bipolar I Disorder

United States, Canada
Levita Magnetics

Recruiting

Safety and Feasibility of Liver Retraction With the Levita Magnetic Surgical System: Extended Magnetic Grasper Device

Hiatal Hernia | Bariatric Surgery Candidate

Chile
University of Alberta
University of Calgary

Not yet recruiting

PAUSE: Sick Day Medication Management Mobile App Study (PAUSE)

Adverse Event | Chronic Condition
Octapharma

Not yet recruiting

Post Marketing Observational Study on Safety of BALFAXAR vs. KCENTRA for Reversal of Vitamin K Antagonist Induced Anticoagulation in Adults Undergoing Urgent Surgery or Invasive Procedure

Significant Bleeding Risk | Vitamin K-Dependent Coagulation Defect
Ionis Pharmaceuticals, Inc.

Not yet recruiting

ATTUNE: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Intrathecally-Administered ION440 in Participants With Methyl CpG Binding Protein 2 (MECP2) Duplication Syndrome (MDS)

Methyl CpG Binding Protein 2 (MECP2) Duplication Syndrome
Erzincan Military Hospital

Not yet recruiting

Evaluating the Efficacy and Safety of Preoperative Administration of Duloxetine for Pain Management in Women Undergoing Vaginal Hysterectomy.

Postoperative Pain | Vaginal Hysterectomy
Hookipa Biotech GmbH

Not yet recruiting

Safety, Reactogenicity and Immunogenicity of HB-502 and HB-501 Versus Placebo in People With HIV on Suppressive ART

Human Immunodeficiency Virus (HIV) Infection

United States
Sichuan University

Recruiting

Safety and Efficacy of Whole Brain LDRT+ICI+Intrathecal Chemotherapy in Refractory Meningeal Metastasis of Lung Cancer

NSCLC | PD-1 Inhibitor | Leptomeningeal Metastasis | Low Dose Radiotherapy

China
GlaxoSmithKline

Recruiting

A Study to Find the Dose and Assess the Immune Response and Safety of a Vaccine Against Influenza in Healthy Younger and Older Adults

Influenza, Human

United States

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