Search clinical trials for: Immunomodulatory agent

Total 189818 results

Haukeland University Hospital
Oslo University Hospital; The Kavli Foundation

Completed

Cyclophosphamide in Myalgic Encephalopathy/ Chronic Fatigue Syndrome (ME/CFS) (CycloME)

Chronic Fatigue Syndrome (CFS) | Myalgic Encephalomyelitis (ME)

Norway
Liaquat University of Medical & Health Sciences

Completed

Trial to Study the Adjuvant Benefits of Quercetin Phytosome in Patients With COVID-19

COVID-19

Pakistan
Hoffmann-La Roche

Completed

A Study of Atezolizumab (Anti-Programmed Death-Ligand 1 [PD-L1] Antibody) Alone or in Combination With an Immunomodulatory Drug and/or Daratumumab in Participants With Multiple Myeloma (MM)

Multiple Myeloma

United States
Gilead Sciences

Completed

Study to Investigate Idelalisib in Combination With Chemotherapeutic Agents, Immunomodulatory Agents and Anti-CD20 Monoclonal Antibody (mAb) in Participants With Relapsed or Refractory Indolent B-cell Non-Hodgkin's Lymphoma, Mantle Cell Lymphoma or Chronic Lymphocytic Leukemia

Mantle Cell Lymphoma | Chronic Lymphocytic Leukemia | Indolent Non-Hodgkin's Lymphoma

United States
Barretos Cancer Hospital
Farmoquimica S.A.

Completed

Randomized Clinical Trial Evaluating the Efficacy of Topical Imiquimod in High Grade Cervical Intraepithelial Lesions

Cervix Cancer | High Grade Intraepithelial Neoplasia

Brazil
Bosnalijek D.D

Completed

Clinical Trial to Evaluate the Efficacy and Safety of an Immunomodulatory Therapy for the Treatment of Patients With Moderate to Severe COVID-19 Infection

COVID-19 Infection

Bosnia and Herzegovina
Famewave Ltd.

Terminated

Study of CM-24 (MK-6018) Alone and In Combination With Pembrolizumab (MK-3475) in Participants With Selected Advanced or Recurrent Malignancies (MK-6018-001)

Melanoma | Gastric Cancer | Colorectal Cancer | Ovarian Cancer | Bladder Cancer | Non-small Cell Lung Carcinoma (NSCLC)

United States, Israel
University of California, San Francisco
Pfizer; Stanford University; amfAR, The Foundation for AIDS Research; Case Western... and other collaborators

Completed

Maraviroc as an Immunomodulatory Drug for Antiretroviral-treated HIV Infected Patients Exhibiting Immunologic Failure

HIV Infection

United States
Aljazeera Hospital

Completed

The Role of Immunomodulatory Treatment in Success of ICSI in Patients With Autoimmune Thyroiditis

Infertility | Autoimmune Thyroiditis

Egypt
Shenzhen Geno-Immune Medical Institute
Shenzhen Children's Hospital; Shenzhen Hospital of Southern Medical University

Unknown

Immune Modulatory DC Vaccine Against Brain Tumor

Diffuse Intrinsic Pontine Glioma or Glioblastoma

China
Al-Neelain University
University of Khartoum

Unknown

Potential Role of Gum Arabic as Immunomodulatory Agent Among COVID 19 Patients (GA&COVID19)

COVID 19

Sudan
Gustave Roussy, Cancer Campus, Grand Paris

Unknown

Ex-vivo Evaluation of the Reactivity of the Immune Infiltrate of Cancers to Treatments With Monoclonal Antibodies Targeting the Immunomodulatory Pathways (MAB IN SITRO)

Cancer

France
Hoffmann-La Roche

Completed

A Study Evaluating the Safety and Pharmacology of Atezolizumab Administered in Combination With Immunomodulatory Agents in Participants With Acute Myeloid Leukemia (AML)

Acute Myeloid Leukemia

United States
National Cancer Institute (NCI)

Terminated

Combination Therapy of Interleukin-12 and Interleukin-2 to Treat Advanced Cancer

Sarcoma | Breast Neoplasm | Lung Neoplasm | Kidney Neoplasm

United States
National Cancer Institute (NCI)
Millennium Pharmaceuticals, Inc.

Withdrawn

Phase II Study of Subcutaneous (SC) Bortezomib, Lenalidomide and Dexamethasone for Relapsed and/or Refractory Multiple Myeloma; Followed by SC Bortezomib Maintenance

Multiple Myeloma
National Cancer Institute (NCI)

Completed

Pomalidomide for Chronic Graft-versus-Host Disease

Graft vs Host Disease | Graft-Versus-Host Disease

United States
Universitas Padjadjaran
Hasan Sadikin General Hospital

Completed

Immunomodulatory Vitamin D in Thalassemia (ThalTB)

Vitamin D Deficiency | Tuberculosis | Thalassemia

Indonesia
Mehdi Yousefi

Completed

Immunomodulatory Effects of Rapamycin on Pregnancy Rate of Patient With Recurrent Implantation Failure

Recurrent Implantation Failure

Iran, Islamic Republic of
Idera Pharmaceuticals, Inc.

Completed

Placebo-controlled, Dose-escalation Study of the Safety of IMO-2125 (Immunomodulatory Oligonucleotide) in Hepatitis C-infected Patients

Hepatitis C

United States, Puerto Rico
Sisters of Mercy University Hospital
Clinical Hospital Centre Zagreb

Unknown

The Immunomodulatory Effect of Antrifibrinolytic (Tranexamic Acid) in Total Knee Arthroplasty

Hemorrhage

Croatia
University of Chicago

Terminated

Statins for the Early Treatment of Sepsis (SETS)

Sepsis

United States
Maastricht University Medical Center

Completed

Increasing Ferulic Acid Bioavailability in Bran

Healthy Males

Netherlands
Janssen Research & Development, LLC

Completed

An Efficacy and Safety Study of Daratumumab in Patients With Multiple Myeloma Who Have Received at Least 3 Prior Lines of Therapy (Including a Proteasome Inhibitor [PI] and Immunomodulatory Drug [IMiD]) or Are Double Refractory to a PI and an IMiD

Multiple Myeloma

United States, Spain, Canada
King Abdullah International Medical Research Center
Hoffmann-La Roche

Unknown

To Study the Effect of Adding on Pegylated Interferon (PEG-INF) Therapy for Patients Diagnosed With Chronic Hepatitis B (RC14/055)

Hepatitis B

Saudi Arabia
National Cancer Institute (NCI)
Celgene Corporation

Terminated

Lenalidomide Maintenance Therapy for Multiple Myeloma

Multiple Myeloma

United States
Beth Israel Deaconess Medical Center

Completed

Immunomodulatory Properties of Ketamine in Sepsis

Sepsis

United States
National Institute of Allergy and Infectious Diseases...

Completed

Effect of Leflunomide on T Cell Proliferation in HIV-Infected Patients

HIV Infections

United States
National Institute of Mental Health (NIMH)

Completed

Effects of an Anti-Inflammatory Drug in Alzheimer's Disease

Alzheimer's Disease

United States
GlaxoSmithKline

Completed

Establishing Predictors of Enlarged Prostate Treatment Adherence: Linking Symptom Improvement to Adherence

Prostatic Hyperplasia
University Health Network, Toronto
Celgene Corporation

Completed

Open-Label Study of Lenalidomide in Combination With Oral Dexamethasone in the Treatment of Previously Untreated, Symptomatic Patients With Chronic Lymphocytic Leukemia

Chronic Lymphocytic Leukemia

Canada
Rabin Medical Center

Withdrawn

Use of Azithromycin as Immunomodulatory Therapy in Grave&Apos;s Orbitopathy

Graves Ophthalmopathy
Shanghai First Maternity and Infant Hospital

Unknown

The Novel Immunomodulatory and Anticoagulant Therapies for Recurrent Pregnancy Loss

Recurrent Pregnancy Loss

China
Bionor Immuno AS
Celgene Corporation

Completed

Vacc-4x + Lenalidomide vs. Vacc-4x +Placebo in HIV-1-infected Subjects on Antiretroviral Therapy (ART) (IMID)

HIV-1 Infection

Germany
National Institute of Allergy and Infectious Diseases...
Cooperative Clinical Trials in Pediatric Transplantation

Completed

Safety in Immunomodulatory Functions of Alemtuzumab (Campath) in Pediatric Kidney Transplantation Recipients

Kidney Failure, Chronic | Kidney Transplantation | Immunosuppression

United States
Sarah Network of Rehabilitation Hospitals
University of Brasilia

Unknown

Immune Effect of Dexmedetomidine in Patients Undergoing to Spinal Fusion (eMUNODEX)

Spondylolisthesis | Spondylolysis | Spine; Arthrosis | Spondylolysis, Multiple Sites in Spine

Brazil
Yale University
Celgene Corporation

Completed

Continuous Versus Intermittent Dosing Regimens for Pomalidomide in Relapsed/Refractory Multiple Myeloma

Multiple Myeloma

United States
University Health Network, Toronto
Celgene

Terminated

Study of Lenalidomide in Previously Untreated, Symptomatic Chronic Lymphocytic Leukemia (CLL) (Rev-CLL)

Chronic Lymphocytic Leukaemia

Canada
Fundación Pública Andaluza para la gestión de la...

Completed

Immunomodulatory Effect of Vitamin D in Allogenic Post-transplant (Alovita-1)

Hematopoietic Stem Cell Transplantation

Spain
Genzyme, a Sanofi Company

Completed

An Exploratory Study of the Safety and Efficacy of Prophylactic Immunomodulatory Treatment in Myozyme-naive Cross-Reacting Immunologic Material (CRIM[-]) Patients With Infantile-Onset Pompe Disease

Glycogen Storage Disease Type II | Pompe Disease

United States
University of Roma La Sapienza

Withdrawn

Efficacy and Safety of Top-down Therapy in Pediatric Crohn's Disease

Pediatric Crohn's Disease

Italy
National Institute of Allergy and Infectious Diseases...

Withdrawn

Lupus Immunosuppressive/Immunomodulatory Therapy or Stem Cell Transplant (LIST)

Systemic Lupus Erythematosus

United States
Shiraz University of Medical Sciences

Completed

Immunomodulatory Effects of Silymarin in Patients With Beta-Thalassemia Major

Immune Abnormalities

Iran, Islamic Republic of
Agennix

Completed

Safety and Efficacy of Talactoferrin in Previously Treated Patients With Non-small Cell Lung Cancer (FORTIS-M)

Non Small Cell Lung Cancer

United States, Spain, France, Canada, Bulgaria, Australia, Russian Federation, Turkey, Taiwan, Hungary, Philippines, Czech Republic, Germany, Greece, India, Italy, Korea, Republic of, Latvia, Malaysia, Poland, Romania, Singapore, United...
SciClone Pharmaceuticals

Completed

Proof-of-concept Study to Evaluate the Safety and Immunomodulatory Effects of SCV 07 as Monotherapy or in Combination With Ribavirin in Noncirrhotic Subjects With Chronic Hepatitis C Who Have Relapsed

Chronic Hepatitis C

United States
University of Florida
American Heart Association; American College of Clinical Pharmacy

Completed

Systemic Immunomodulatory Effects and Pharmacogenetics of Atorvastatin in Early Atherosclerosis

Inflammation

United States
Sharon Lynch, MD
EMD Serono

Completed

Cognitive Effects of Immunomodulatory Drugs in MS

Multiple Sclerosis

United States
Agennix

Unknown

Safety and Efficacy of Talactoferrin in Addition to Standard Chemotherapy in Patients With Non-small Cell Lung Cancer (FORTIS-C)

Non Small Cell Lung Cancer

United States
Universidad de Antioquia
Instituto Colombiano para el Desarrollo de la Ciencia y la Tecnología (COLCIENCIAS) and other collaborators

Completed

Lovastatin: Immunomodulatory Value Evaluation (LIVE)

HIV Seropositivity

Colombia
University of California, San Diego
Genentech, Inc.

Completed

Assessment of Rituximab's Immunomodulatory Synovial Effects (The ARISE Study)

Rheumatoid Arthritis

United States
Academisch Medisch Centrum - Universiteit van Amsterdam...
Hoffmann-La Roche; Sanquin Research & Blood Bank Divisions

Unknown

Mycophenolate Mofetil in Antiretroviral Naïve Patients 2 (MAN2 Study)

HIV Infection

Netherlands

Search clinical trials for: Immunomodulatory agent

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