Search clinical trials for: Lumefantrine Solid Dispersion Formulation

Total 11759 results

Bayer

Completed

Study in Healthy Adult Male Participants to Gather Information How the Human Body Absorbs, Distributes and Excretes the Study Drug Selitrectinib Including the Effect of the Interaction of Food With the Study Drug on the Human Body

Solid Tumors Harboring NTRK Fusion

Germany
Novartis Pharmaceuticals

Completed

Bioequivalence of 2 Formulations of TKI258 in Patients With Advanced Solid Tumors

Advanced Solid Tumors | Excluding Breast Cancer

United States
Arthrosi Therapeutics

Completed

The Study is Designed to Evaluate Single Ascending Doses of AR882 in Healthy Adult Males

Healthy Volunteers

Australia
Amgen

Completed

A Study to Evaluate the Safety, Tolerability Pharmacokinetics, and Pharmacodynamics of a New Spray Dried Dispersion (SDD) Formulation of CC-11050 After Single Dose of CC-11050 and to Evaluate the Pharmacokinetics of CC-11050 Under Fasted and Fed Conditions and After Coadministration With Omeprazole

Healthy Volunteers

United States
AstraZeneca
Quotient Sciences

Completed

AZD4635 Relative Bioavailability Study (Rel Bio)

Healthy Volunteers

United Kingdom
Janssen Research & Development, LLC

Terminated

A Study of JNJ-64140284 Solid Dose Formulations in Healthy Male Participants

Healthy

Belgium
Bausch Health Americas, Inc.

Completed

Dose-ranging Study of Rifaximin Soluble Solid Dispersion (SSD) Tablets for the Prevention of Complications of Early Decompensated Liver Cirrhosis

Liver Cirrhosis

United States, Russian Federation
Eisai Limited

Completed

An Open-label, Multicenter, Multiple Dose, Phase 1 Study to Establish the Maximum Tolerated Dose of E7389 Liposomal Formulation in Patients With Solid Tumors

Solid Tumors

United Kingdom
InnoPharmax Inc.

Completed

Phase1 Study of Gemcitabine HCl Oral Formulation(D07001-F4) in Patients With Advanced Solid Malignancies and Malignant Lymphomas

Advanced Solid Malignancies | Malignant Lymphomas

Taiwan
Hoffmann-La Roche

Terminated

Study of Intravenous RXDX-107 in Patients With Solid Tumors

Solid Tumor

United States
Daiichi Sankyo, Inc.
ICON Clinical Research; ArQule, Inc. (a wholly owned subsidiary of Merck Sharp...

Completed

Determination of the Relative Bioavailability of ARQ 197 Tablet Formulation With Capsule C Formulation as a Reference in Subjects With Advanced Solid Tumors

Solid Tumors

United States
Merck Sharp & Dohme LLC

Terminated

Study of Robatumumab (SCH 717454, MK-7454) in Combination With Different Treatment Regimens in Participants With Advanced Solid Tumors (P04722, MK-7454-004)

Neoplasms
University of British Columbia
Simon Fraser University; Astellas Pharma Canada, Inc.

Completed

Comparison of Medication Adherence Between Once and Twice Daily Tacrolimus in Stable Renal Transplant Recipients

Renal Transplant | Renal Disease

Canada
Takeda

Completed

TAK-020 Relative Bioavailability and Food Effect Study in Healthy Participants

Healthy

United Kingdom
City of Hope Medical Center
National Cancer Institute (NCI); National Comprehensive Cancer Network

Completed

Intraperitoneal Paclitaxel Albumin-Stabilized Nanoparticle Formulation in Treating Patients With Advanced Cancer of the Peritoneal Cavity

Ovarian Cancer | Peritoneal Cavity Cancer | Unspecified Adult Solid Tumor, Protocol Specific

United States
University of California, Davis
Eli Lilly and Company; Celgene

Terminated

Abraxane and Alimta in Advanced Solid Tumors

Breast Cancer | Lung Cancer | Unspecified Adult Solid Tumor, Protocol Specific

United States
Masonic Cancer Center, University of Minnesota

Completed

Bortezomib and Cetuximab in Treating Patients With Advanced Solid Tumors

Sarcoma | Kidney Cancer | Breast Cancer | Head and Neck Cancer | Colorectal Cancer | Pancreatic Cancer | Lung Cancer | Unspecified Adult Solid Tumor, Protocol Specific

United States
AbbVie

Completed

To Determine the Food Effect and Bioavailability of Three Formulations of Veliparib in Subjects With Solid Tumors

Solid Tumors
AbbVie
Genentech, Inc.

Completed

Assess the Oral Bioavailability of a New ABT-263 Formulation in Subjects With Cancer

Solid Tumors | Lymphoid Malignancy
GlaxoSmithKline

Completed

Relative Bioavailibilty for Pediatric Powder for Suspension (PfOS) Formulation

Cancer

United States
Endo Pharmaceuticals
Quintiles, Inc.

Completed

Evaluate Weight Gain Using 2 Different Formulations of Megestrol Acetate Oral Suspension for AIDS-related Weight Loss

HIV Infections | Anorexia | Cachexia | HIV Wasting Syndrome | AIDS Wasting Syndrome

United States, India, South Africa
GlaxoSmithKline

Completed

A Bioequivalence Study of Two Oral Formulations of Topotecan in Patients With Advanced Solid Tumors

Solid Tumor Cancer | Lung Cancer, Small Cell

United States, Canada
GlaxoSmithKline

Completed

Bioavailability Study of Candesartan Cilexetil 8mg Tablet Under Fasting Conditions

Hypertension

India
University of California, Davis
National Cancer Institute (NCI)

Completed

Erlotinib and Cetuximab in Treating Patients With Advanced Solid Tumors With Emphasis on Non-Small Cell Lung Cancer

Lung Cancer | Unspecified Adult Solid Tumor, Protocol Specific

United States
Beth Israel Deaconess Medical Center
National Center for Research Resources (NCRR); Harvard University

Completed

Effect on Acetaminophen Metabolism by Liquid Formulations

Acetaminophen Poisoning | Acetaminophen Metabolism | Drug Metabolism by Excipients

United States
Samyang Biopharmaceuticals Corporation

Completed

A Trial to Determine the Maximum Tolerated Dose and Evaluate the Safety and Pharmacokinetics of Docetaxel-PNP, Polymeric Nanoparticle Formulation of Docetaxel, in Subjects With Advanced Solid Malignancies

Advanced Solid Malignancies

Korea, Republic of
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Bioavailability, Safety and Tolerability of a Solid Dosage Formulation Relative to a Suspension of JNJ-54175446 in Healthy Male and Female Participants

Healthy

United States
Daehwa Pharmaceutical Co., Ltd.

Completed

A Study DHP107, a Novel Oral Paclitaxel Formulation, in Patients With Advanced Solid Tumours or Gastric Cancer

Solid Tumor | Stage IV Gastric Cancer

Korea, Republic of
Hoffmann-La Roche

Completed

A Study of Valcyte (Valganciclovir) Syrup Formulation in Pediatric Solid Organ Transplant Recipients

Cytomegalovirus Infections

Spain, France, Germany, Mexico, United States, Australia, Canada
AstraZeneca

Completed

To Assess the Effect of Itraconazole (a CYP3A4 Inhibitor) on the Pharmacokinetics of Olaparib, and the Effect of Olaparib on QT Interval Following Oral Dosing of a Tablet Formulation to Patients With Advanced Solid Tumours

Solid Tumours

Belgium, Denmark, United Kingdom, Netherlands
AstraZeneca

Completed

Comparison of Two Formulations of AZD5363 and the Effect of Food on Pharmacokinetic Exposure, Safety and Tolerability (OAK)

Safety and Tolerability, | Advanced Solid Malignancy, | Pharmacokinetics, Pharmacodynamics, | Tumour Response,

United Kingdom, Netherlands
R-Pharm

Terminated

Phase 1 Trial of Oral Ixabepilone

Advanced Solid Tumors

United States
Eli Lilly and Company

Completed

Study to Evaluate the Effect of Cetuximab on Corrected QT (QTc) Interval Changes in Patients With Advanced Malignancies From Solid Tumors

Advanced Cancer

Puerto Rico, United States
Eli Lilly and Company

Completed

Study of Cetuximab in Combination With Tarceva in Patients With Solid Tumors

Neoplasms

United States
Galapagos NV

Completed

Oral Bioavailability of Solid Formulation of GLPG1837 With and Without Food

Healthy

Belgium
Pfizer

Withdrawn

A Comparison Of The Pharmacokinetics Of PF-04191834 Following Single Dose Administration Of A Dispersion Formulation And A Suspension Formulation In Healthy Volunteers

Healthy
Hoffmann-La Roche

Completed

A Study of the Drug-Drug Interaction of RO5503781 and Posaconazole, the Relative Bioavailability of New Formulations of RO5503781 and the Food-Effect on the Pharmacokinetics of RO5503781 in Patients With Solid Tumors

Neoplasms

Canada, United States
National Cancer Institute (NCI)

Completed

Veliparib, Carboplatin, and Paclitaxel in Treating Patients With Advanced Solid Cancer

Hereditary Breast and Ovarian Cancer Syndrome | Adult Solid Neoplasm | BRCA1 Mutation Carrier | BRCA2 Mutation Carrier

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI); Novartis

Withdrawn

Dovitinib Lactate, Gemcitabine Hydrochloride, and Paclitaxel Albumin-Stabilized Nanoparticle Formulation in Treating Patients With Advanced Solid Tumors or Pancreatic Cancer

Unspecified Adult Solid Tumor, Protocol Specific | Duct Cell Adenocarcinoma of the Pancreas | Recurrent Pancreatic Cancer | Stage III Pancreatic Cancer | Stage IV Pancreatic Cancer

United States
Janssen Research & Development, LLC

Completed

A Study to Evaluate Bioavailability, Food Effect, Safety and Tolerability of a Solid Dosage Formulation of JNJ-54861911 in Healthy Older Male Participants

Healthy

Belgium
Clovis Oncology, Inc.

Completed

Safety and Pharmacokinetic Profiles of Two Formulations of CO-1.01 in Patients With Advanced Solid Tumors

Advanced Solid Tumor

Netherlands
Galapagos NV

Completed

Oral Bioavailability of Solid Formulation of GLPG1205 With and Without Food

Healthy

Belgium
University of California, San Francisco
National Cancer Institute (NCI)

Completed

Lapatinib and Paclitaxel in Treating Patients With Advanced Solid Tumors

Breast Cancer | Gastric Cancer | Esophageal Cancer | Ovarian Cancer | Lung Cancer | Prostate Cancer | Brain and Central Nervous System Tumors | Bladder Cancer | Extragonadal Germ Cell Tumor

United States
AstraZeneca

Completed

Relative Bioavailability Study to Assess Two Solid Formulations Compared to an Oral Solution of AZD3293 in Healthy Male and Non-Fertile Female Subjects (BA)

Healthy Volunteers | Pharmacologic Action

United States
Genzyme, a Sanofi Company

Completed

Study of Oral Clofarabine Administered Daily for 5 Days in Adult Patients With Refractory Solid Tumors

Solid Tumors

United States
Genzyme, a Sanofi Company

Completed

Clofarabine in Adult Patients With Advanced Solid Tumors

Solid Tumors | Leukemia, Myelocytic, Acute, Pediatric | Leukemia, Lymphocytic, Acute, Pediatric | Leukemia, Lymphocytic, Acute, Adult | Leukemia, Myelocytic, Acute, Adult | Myelodysplastic Syndromes, Adult

United States
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study of Solid Formulations of JNJ-39393406 in Healthy Male Participants

Healthy

Belgium
Galapagos NV

Completed

Oral Bioavailability of Two Solid Formulations of GLPG0634

Healthy

Belgium
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study to Evaluate the Relative Bioavailability, Food Effect and Effect of Ketoconazole on the Rate and Extent of Absorption of Solid Dosage Formulation(s) of JNJ-40411813

Healthy

Belgium
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI)

Terminated

Studying Fentanyl in Patients With Cancer

Pain | Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Brain and Central Nervous System Tumors | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Precancerous Condition | Lymphoproliferative Disorder | Myelodysplastic/Myeloproliferative...

United States

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