Search clinical trials for: Muscle Biopsy

Total 14819 results

King's College London
Royal Free Hospital NHS Foundation Trust; Chelsea and Westminster NHS Foundation... and other collaborators

Recruiting

Muscle Connective Tissue in Limb Development and Disease

Radial Dysplasia

United Kingdom
University Hospital, Brest

Recruiting

Metabolic Exercise Testing (RANNOU)

Myalgia | Exercise Test | Metabolic Myopathies

France
University of Michigan

Recruiting

Identification of Phenotypic Factors That Predict Success for Weight Loss and Long-term Weight Maintenance

Obesity

United States
National Cancer Institute (NCI)

Active, not recruiting

Chemoradiotherapy With or Without Atezolizumab in Treating Patients With Localized Muscle Invasive Bladder Cancer

Bladder Urothelial Carcinoma | Stage IIIA Bladder Cancer AJCC v8 | Muscle Invasive Bladder Carcinoma | Stage II Bladder Cancer AJCC v8

United States
National Cancer Institute (NCI)

Suspended

Testing Ipilimumab and Nivolumab Combination With or Without Cabozantinib in People >= 18 Years Old With Advanced Soft Tissue Sarcoma

Locally Advanced Leiomyosarcoma | Metastatic Undifferentiated Pleomorphic Sarcoma | Locally Advanced Liposarcoma | Locally Advanced Undifferentiated Pleomorphic Sarcoma | Locally Advanced Extraskeletal Myxoid Chondrosarcoma | Locally Advanced Unresectable Soft Tissue Sarcoma

United States, Canada
National Cancer Institute (NCI)

Active, not recruiting

Tipifarnib for the Treatment of Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With HRAS Gene Alterations, a Pediatric MATCH Treatment Trial

Malignant Solid Neoplasm | Recurrent Melanoma | Recurrent Ependymoma | Recurrent Ewing Sarcoma | Recurrent Hepatoblastoma | Recurrent Langerhans Cell Histiocytosis | Recurrent Malignant Germ Cell Tumor | Recurrent Malignant Glioma | Recurrent Medulloblastoma | Recurrent Neuroblastoma | Recurrent Non-Hodgkin... and other conditions

United States, Puerto Rico
National Cancer Institute (NCI)

Active, not recruiting

Erdafitinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With FGFR Mutations (A Pediatric MATCH Treatment Trial)

Recurrent Childhood Medulloblastoma | Recurrent Childhood Ependymoma | Advanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | Recurrent Hepatoblastoma | Recurrent Langerhans Cell Histiocytosis | Recurrent Malignant Glioma | Recurrent Malignant Solid Neoplasm | Recurrent Neuroblastoma and other conditions

United States, Puerto Rico
National Cancer Institute (NCI)

Active, not recruiting

Larotrectinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With NTRK Fusions (A Pediatric MATCH Treatment Trial)

Advanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | Recurrent Ependymoma | Recurrent Hepatoblastoma | Recurrent Langerhans Cell Histiocytosis | Recurrent Malignant Germ Cell Tumor | Recurrent Malignant Glioma | Recurrent Malignant Solid Neoplasm | Recurrent Medulloblastoma | Recurrent... and other conditions

United States, Puerto Rico
Mayo Clinic
United Therapeutics

Enrolling by invitation

A Study of Treprostinil to Treat Interstitial Lung Disease Pulmonary Hypertension

Pulmonary Arterial Hypertension | Interstitial Lung Disease | Healthy Adults

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI); Janssen Research & Development, LLC

Active, not recruiting

Daratumumab in Treating Patients With Muscle Invasive Bladder Cancer or Metastatic Kidney Cancer

Clear Cell Renal Cell Carcinoma | Stage IV Renal Cell Cancer AJCC v8 | Bladder Urothelial Carcinoma | Metastatic Kidney Carcinoma | Malignant Urinary System Neoplasm

United States
National Cancer Institute (NCI)

Active, not recruiting

A Phase II Clinical Trial Evaluating the Combination of Olaparib and Temozolomide for the Treatment of Advanced Uterine Leiomyosarcoma

Stage III Uterine Corpus Leiomyosarcoma AJCC v8 | Stage IV Uterine Corpus Leiomyosarcoma AJCC v8 | Uterine Corpus Leiomyosarcoma

United States
Sahlgrenska University Hospital, Sweden

Active, not recruiting

Rupture of Thumb's Long Extensor Tendon After Fracture of the Distal Radius, Study of Muscle and Tendon Pathology

Distal Radius Fractures | Pathology | Tendon Injury - Hand

Sweden
National Cancer Institute (NCI)

Active, not recruiting

Talimogene Laherparepvec and Radiation Therapy in Treating Patients With Newly Diagnosed Soft Tissue Sarcoma That Can Be Removed by Surgery

Soft Tissue Sarcoma | Leiomyosarcoma | Liposarcoma | Undifferentiated Pleomorphic Sarcoma | Soft Tissue Sarcoma of the Trunk and Extremities | Stage I Soft Tissue Sarcoma AJCC v7 | Stage II Soft Tissue Sarcoma AJCC v7 | Sarcoma G2 | Sarcoma G3

United States, Canada
AdventHealth Translational Research Institute

Active, not recruiting

Electrical Stimulation of Human Myocytes in Microgravity (microG)

Sarcopenia

United States
AdventHealth Translational Research Institute

Active, not recruiting

Measurement of NAD+ Synthesis in Human Skeletal Muscle (NAD-flux)

Skeletal Muscle

United States
Riphah International University

Completed

Impact of Focal Muscle Vibration on Bio-psychosocial Outcomes in Cerebral Palsy

Cerebral Palsy

Pakistan
Fang Jun

Completed

The Role of Remazolam in Reducing the Incidence of Postoperative Delirium in Elderly Patients

Postoperative Delirium

China
Liverpool John Moores University
Liverpool University Hospitals NHS Foundation Trust; Royal Liverpool University... and other collaborators

Active, not recruiting

Can Brisk Walking Combined With Ingestion of a Lipid-lowering Drug Improve Fat Metabolism in Muscle?

Pre Diabetes

United Kingdom
National Cancer Institute (NCI)

Completed

Durvalumab and Vicineum in Subjects With High-Grade Non-Muscle-Invasive Bladder Cancer Previously Treated With Bacillus Calmette-Guerin (BCG)

Urinary Bladder Neoplasms

United States
Mayo Clinic
National Institute on Aging (NIA); National Center for Research Resources (NCRR)

Completed

Enhancing Adaptations to Exercise

Inflammation

United States
Barts & The London NHS Trust
Imperial College London; Queen Mary University of London

Terminated

Metabolic Myopathy in Endocrinopathy (LYDIA)

Cushing Syndrome | Pheochromocytoma | Conns Syndrome | Metabolic Myopathy

United Kingdom
Pfizer

Completed

Drug-Drug Interaction Study to Estimate the Effect of PF-07321332/Ritonavir and Ritonavir on Midazolam in Healthy Participants

Healthy Participants

Belgium
Merck Sharp & Dohme LLC

Terminated

A Study of Adavosertib (MK-1775) in Combination With Topotecan/Cisplatin in Participants With Cervical Cancer (MK-1775-008)

Cervical Cancer
Duke University
Gilead Sciences

Completed

MusculRA: The Effects of Rheumatoid Arthritis on Skeletal Muscle Biomechanics (MusculRA)

Rheumatoid Arthritis | Healthy Controls

United States
Hacettepe University

Completed

The Effect of Cognitive Exercise Therapy Approach in Individuals With Systemic Sclerosis

Systemic Sclerosis

Turkey
University of Florida
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and other collaborators

Withdrawn

The Role of Muscle Cachexia in Pancreatic Cancer

Pancreas Cancer

United States
Institut de cancérologie Strasbourg Europe
Université de Strasbourg - Unité de Recherche 3072 - Mitochondries, Stress...

Completed

Acute Effects of Chemotherapy Administration on Skeletal Muscle of Breast Cancer Patients: the PROTECT-06 Study (PROTECT-06)

Breast Cancer

France
Rennes University Hospital

Completed

Evaluation of Hepatic Rigidity by Ultrasonic Impulse Elastography in Liver Transplant Patients (SUPERSONIC)

Hepatic Transplantation

France
Nordsjaellands Hospital
University of Copenhagen; Steno Diabetes Center Copenhagen; Danish Research Centre...

Active, not recruiting

Metabolic Adaptation to High-frequent Hypoglycaemia in Type 1 Diabetes (HypoADAPT)

Type1diabetes

Denmark
Mayo Clinic
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

PET Imaging to Delineate Macrophage Activation in Diabetic Gastroparesis

Diabetes | Gastroparesis With Diabetes Mellitus

United States
PepsiCo Global R&D

Completed

Investigating the Efficacy of Low or High Dose Tart Cherry on Recovery From Exercise Induced Muscle Damage and Establishing Its Molecular Mechanisms of Action

Muscle Recovery

United Kingdom
University of Texas Southwestern Medical Center

Terminated

7T Magnetic Resonance Spectroscopy and Skeletal Muscle Biopsy Findings in Statin Associated Adverse Muscle Events

Muscle Cramp | Statin Adverse Reaction | Weakness, Muscle | Ache

United States
Minsk Scientific-Practical Center for Surgery,...
Belarusian State Medical University

Completed

Pneumococcal Vaccination of Multiple Myeloma Patients on Novel Agents

Multiple Myeloma | Febrile Neutropenia | Pneumococcal Pneumonia | Pneumococcal Infection

Belarus
Centre Hospitalier Universitaire de Saint Etienne

Terminated

Skeletal Muscle Expression of Myostatin and Cancer of Digestive System Associated Cachexia (MYOCAC)

Cancer of Digestive System

France
Washington University School of Medicine

Active, not recruiting

Composition & Function of Sarcoplasmic Reticulum in Persons With the Metabolic Syndrome (COMP-SR)

Metabolic Syndrome

United States
Sanni Raju
Ohio State University

Completed

Effects of PrimaVie and Exercise Training on Human Skeletal Muscle (PrimaVie)

Obesity

United States
Hasselt University
Jessa Hospital; Ziekenhuis Oost-Limburg

Completed

Paraspinal Muscle Remodeling

Lumbar Disc Herniation

Belgium
Montreal Heart Institute
Ingenew Pharmaceuticals Inc.

Completed

Study of Hesperidin Therapy on COVID-19 Symptoms (HESPERIDIN) (Hesperidin)

Pain | Confusion | Covid19 | Nausea | Vomiting | Cough | Muscle Weakness | Fever | Headache | Anosmia | Sore Throat | Shortness of Breath | Pain, Joint | Pain, Chest | Irritable Mood | Pain, Abdominal | Pain, Muscle

Canada
Assistance Publique - Hôpitaux de Paris

Active, not recruiting

Presymptomatic Neuromuscular Junction Defects and Compensatory Mechanisms in ALS (PRE-ALS)

Amyotrophic Lateral Sclerosis

France
University of Florida
National Institute on Aging (NIA)

Withdrawn

Inflammation Control For Elders: ICE Study (ICE)

Inflammation | Aging
University Hospital, Montpellier
Hill-Rom

Terminated

Quantification of the Pressure Threshold Related to Tissue Injury in Bedriden Paraplegics

Spinal Cord Injury | Pressure Ulcer | Paraplegia | Bedsore

France
Centre Hospitalier Universitaire de Saint Etienne
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement and other collaborators

Completed

Biological Aging of Skeletal Muscles in Humans (BioAge)

HEALTHY

France
Societa Italiana di Chirurgia ColoRettale
SICCR - Gaetano Gallo

Completed

Efficacy and Safety of Polidocanol Foam 3% in the Treatment of II Degree Hemorrhoidal Disease (SCLEROFOAM)

Second-degree Hemorrhoids

Italy
University Hospital, Montpellier

Completed

Transcervical Myoma Biopsy Video (TMBV)

Myoma | Atypical

France
Hasselt University
Jessa Hospital

Completed

Skeletal Muscle Wasting in SARS-CoV-2 (SMW)

Critical Illness | Cachexia | Muscle Atrophy | Muscle Loss | Muscle Wasting

Belgium
University of Kansas Medical Center
US Department of Veterans Affairs

Withdrawn

Physical Inactivity and Insulin Resistance in Skeletal Muscle.

Hypertension | Obesity | Insulin Resistance | Hypercholesterolemia | Metabolic Syndrome X

United States
PepsiCo Global R&D

Completed

Accelerating Post-exercise Muscle Glycogen Resynthesis in Humans: Impact of Combined Nutrient Intake and Intermittent Pneumatic Compression or Heat Therapy

Muscle Soreness | Muscle Recovery | Glycogen Depletion

United States
Mansoura University

Completed

The Role of mRNA-based Urine Test (Xpert Bladder Cancer Monitor) in Predicting the Need for Second Look Biopsy After Transurethral Resection of Non Muscle-invasive Bladder Tumor.

Bladder Cancer

Egypt
Technical University of Munich
Helmholtz Zentrum München

Completed

Metabolomics Study on Intensive Care Acquired Muscle Weakness in Polytrauma (MIRACLE II)

Critical Illness | Muscle Weakness | Critical Illness Myopathy | Critical Care | Critical Illness Polyneuropathy | Metabolomics | Intensive Care (ICU) Myopathy

Germany
Karolinska Institutet
Region Stockholm; Australian Catholic University; Baker Heart and Diabetes Institute

Completed

Frequent Activity Snacks Breaks (FABS)

Obesity | Sedentary Lifestyle | Insulin Resistance

Sweden

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