Search clinical trials for: PUMA

Total 97 results

NSABP Foundation Inc
Puma Biotechnology, Inc.

Completed

Phase II Randomized Trial Evaluating Neoadjuvant Therapy With Neratinib and/or Trastuzumab Followed by Postoperative Trastuzumab in Women With Locally Advanced HER2-positive Breast Cancer

Breast Cancer

United States, Canada, Puerto Rico, Italy, Spain
Zealand University Hospital

Completed

Remote Ischemic Preconditioning in Patients Undergoing Acute Minor Abdominal Surgery (PUMAS)

Endothelial Dysfunction | Acute Cholecystitis

Denmark
Puma Biotechnology, Inc.

Completed

Study Evaluating The Effects Of Neratinib After Adjuvant Trastuzumab In Women With Early Stage Breast Cancer (ExteNET)

Breast Cancer

United States, Spain, Korea, Republic of, China, United Kingdom, Canada, France, Australia, Denmark, Switzerland, Japan, Malaysia, Italy, Singapore, Taiwan, Belgium, Croatia, Czechia, Romania, Germany, Bahamas, Brazil, Bulgaria, Colombia and more
Puma Biotechnology, Inc.

Completed

A Study of Neratinib Plus Capecitabine Versus Lapatinib Plus Capecitabine in Patients With HER2+ Metastatic Breast Cancer Who Have Received Two or More Prior HER2 Directed Regimens in the Metastatic Setting (NALA)

HER2+ Metastatic Breast Cancer (MBC)

United States, Canada, Spain, Singapore, Korea, Republic of, Taiwan, United Kingdom, Israel, Australia, Japan, Hong Kong, Finland, Ireland, Italy, France, Portugal, Germany, Sweden, Belgium, Brazil, Czechia, Switzerland, Argentina, Au... and more
Puma Biotechnology, Inc.

Terminated

HER-Seq: A Blood-based Screening Study to Identify Patients With HER2 Mutations for Enrollment Into Clinical Research Studies of Neratinib

Metastatic Cervical Cancer | Hormone Receptor-Positive, HER2-Negative Metastatic Breast Cancer

Spain, Israel, United States, Serbia, France, Ireland, Italy
Hospital Universitario Ramon y Cajal

Unknown

Myofunctional Therapy in Patients With Mild-moderate Sleep Apnea

Obstructive Sleep Apnea of Adult | Myofunctional Therapy

Spain
Gustavo Zabert, MD
AstraZeneca

Unknown

PUMA Implementation 2 (IPUMA2)

COPD | Risk Factors | Diagnosis | Spirometry | Adult | Primary Care | Screening Score

Argentina
Puma Biotechnology, Inc.

Completed

A Study Of Neratinib (HKI-272) And Capecitabine In Japanese With Solid Tumor

Advanced Malignant Solid Tumors

Japan
Puma Biotechnology, Inc.

Completed

Study Evaluating Safety And Tolerability, Solid Tumor

Advanced Malignant Solid Tumors

Japan
Puma Biotechnology, Inc.

Completed

Temsirolimus Plus Neratinib for Patients With Metastatic HER2-Amplified or Triple Negative Breast Cancer

Breast Cancer

Spain, United Kingdom, France, United States, Denmark, Hong Kong
Puma Biotechnology, Inc.

Completed

Study Evaluating Neratinib In Combination With Temsirolimus In Subjects With Solid Tumors

Neoplasms | Malignant Carcinoma

United States, France
Puma Biotechnology, Inc.

Completed

Study Evaluating HKI-272 in Tumors

Breast Neoplasms

United States
Puma Biotechnology, Inc.

Completed

A Study Of The Safety And Tolerability Of HKI-272 Administered Orally To Japanese Subjects With Advanced Solid Tumors

Tumors

Japan
Puma Biotechnology, Inc.

Completed

Study Evaluating The Combination Of Neratinib And Capecitabine In Solid Tumors And Breast Cancer

Breast Cancer

United States, Spain, China, Hungary, Singapore, Australia, Russian Federation, Hong Kong, Brazil, Croatia, Korea, Republic of
Puma Biotechnology, Inc.

Completed

Study Evaluating Neratinib Plus Paclitaxel VS Trastuzumab Plus Paclitaxel In ErbB-2 Positive Advanced Breast Cancer (NEFERTT)

Breast Cancer

Spain, China, United States, Australia, Hong Kong, Malaysia, Korea, Republic of, Singapore, Belgium, Japan, India, France, Hungary, Romania, Italy, Bulgaria, Germany, Serbia, United Kingdom, South Africa, Canada, Israel, Taiwan, Switz... and more
GlaxoSmithKline

Completed

Immunogenicity and Safety of GSK Biologicals' (Pre-) Pandemic Influenza Candidate Vaccine

Influenza

Japan
GlaxoSmithKline

Completed

Study to Evaluate the Safety and Immune Response of Two-Doses of Candidate Influenza Vaccine GSK 1557484A in Adults

Influenza

United States, Canada
Puma Biotechnology, Inc.

Completed

Study Evaluating HKI-272 (Neratinib) In Subjects With Advanced Breast Cancer

Neoplasms | Breast Neoplasms

United States, Belgium, India, China, Russian Federation, Mexico, France
Puma Biotechnology, Inc.

Completed

Study Evaluating Neratinib Versus Lapatinib Plus Capecitabine For ErbB2 Positive Advanced Breast Cancer

Breast Cancer | Advanced Breast Cancer

Korea, Republic of, Taiwan, Hong Kong, United States, Japan, Croatia, United Kingdom, Hungary, Australia, Canada, Serbia, Singapore, South Africa, Poland, Spain, Russian Federation, Romania, Austria, Belgium, Bulgaria, Czechia, Fr... and more
Puma Biotechnology, Inc.

Completed

Study Evaluating Neratinib (HKI-272) In Combination With Vinorelbine In Subjects With Solid Tumors And Metastatic Breast Cancer

Breast Cancer | Advanced Malignant Solid Tumors

United States, Taiwan, United Kingdom, Hong Kong, Belgium, France, Spain, China, Netherlands, Poland, Sweden
Puma Biotechnology, Inc.

Completed

A Phase 1/2 Study of HKI-272 (Neratinib) in Combination With Paclitaxel (Taxol) in Subjects With Solid Tumors and Breast Cancer

Breast Neoplasms | Advanced Breast Cancer | Advanced Malignant Solid Tumors

United States, Belgium, China, Hong Kong, Canada, Korea, Republic of, India, Poland, Ukraine
Puma Biotechnology, Inc.

Completed

A Phase 1/2 Study Of HKI-272 (Neratinib) in Combination With Trastuzumab (Herceptin) In Subjects With Advanced Breast Cancer

Advanced Breast Cancer

United States, Switzerland, China, France
Puma Biotechnology, Inc.

Completed

Neratinib With and Without Temsirolimus for Patients With HER2 Activating Mutations in Non-Small Cell Lung Cancer

HER2-mutant Non-Small Cell Lung Cancer

United States, France
Puma Biotechnology, Inc.

Completed

Study Evaluating Neratinib In Combination With Vinorelbine In Subjects With Advanced Or Metastatic Solid Tumors

Advanced Malignant Solid Tumors

Japan
Puma Biotechnology, Inc.

Completed

Study Evaluating the Safety Of HKI-272 (Neratinib) In Subjects With Advanced Non-Small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung | Lung Neoplasms

United States, France, Hungary, Poland, Spain
Molnlycke Health Care AB

Completed

Mepilex Ag Versus Silver Sulfadiazine in Children and Adults With Burn Injuries.

Burn Injuries

China
Molnlycke Health Care AB

Completed

Evaluating the Cost-effectiveness, Efficacy, Safety and Tolerance of Mepilex® Ag Versus Silvadene®

Second Degree Burn

United States
Eurofarma Laboratorios S.A.

Completed

A Clinical Trial About Treatment of Mild to Moderate Persistent Alergic Rhinnitis With Test or Reference Mometasone (PUMA)

Mild to Moderate Persistent Allergic Rhinitis

Brazil
Puma Biotechnology, Inc.

Completed

Study Evaluating HKI-272 Administered to Healthy Subjects

Healthy

United States
Puma Biotechnology, Inc.

Completed

Open-label PK Study to Evaluate Lansoprazole and Neratinib in Healthy Subjects

Healthy

United States
Cellceutix Corporation
Dana-Farber Cancer Institute; Beth Israel Deaconess Medical Center

Completed

A Safety, Pharmacokinetic and Pharmacodynamic Study of Kevetrin in Patients With Advanced Solid Tumors

Solid Tumors

United States
University of Nottingham

Unknown

Prevalence of Congenital Uterine Malformations (PUMA)

Congenital Uterine Anomalies

United Kingdom
Venus MedTech (HangZhou) Inc.

Unknown

Safety and Performance of TAVI of Venus MedTech Aortic Valve Prosthesis (Venus-A)

Aortic Valve Stenosis | Aortic Valve Calcification

China
Molnlycke Health Care AB

Completed

Evaluating the Efficacy of an Absorbent Foam Dressing Containing Silver (Mepilex Ag) Versus the Same Dressing Without Silver Used on Subjects With Venous Leg Ulcers or Mixed Ulcers

Venous Leg Ulcers | Mixed Leg Ulcers

France, Germany, Netherlands, Czech Republic
Turku University Hospital

Unknown

Computational Modeling for Prediction of Acoustic Changes in Vowel Production Due to Orthognathic Surgery (PUMA)

Facial Asymmetry | Jaw Deformity

Finland
AstraZeneca

Completed

Prevalence Study and Regular Practice Among General Practitioners in Populations at Risk of Chronic Obstructive Pulmonary Disease (COPD) in Latin America (PUMA PROJECT)

Chronic Obstructive Pulmonary Disease

Venezuela, Colombia, Argentina, Uruguay
Puma Biotechnology, Inc.

Completed

A Single Dose Bioequivalence Study Of Neratinib In Healthy Subjects

Healthy

United States
Puma Biotechnology, Inc.

Withdrawn

Study Evaluating The Effect Of A High-Fat Meal On The Pharmacokinetics Of Neratinib

Healthy
Puma Biotechnology, Inc.

Completed

Study Evaluating The Potential Effect Of Rifampin On The Pharmacokinetics Of Neratinib

Healthy Subjects

United States
Puma Biotechnology, Inc.

Completed

Study Comparing 2 New Formulations of HKI-272 in Healthy Adult Subjects

Healthy

United States
Puma Biotechnology, Inc.

Completed

Study Evaluating TwoTablet Formulations of Neratinib (HKI-272)

Healthy Subjects

United States
Puma Biotechnology, Inc.

Completed

Study Evaluating The PK And Safety Of Neratinib In Healthy Subjects And Subjects With Chronic Liver Disease

Hepatic Insufficiency

Russian Federation
Puma Biotechnology, Inc.

Completed

Study Evaluating The Tolerability Of Multiple Doses Of HKI-272

Healthy Subjects

United States
Puma Biotechnology, Inc.

Completed

Study Evaluating The Potential Effect Of Multiple Doses Of Neratinib On The Pharmacokinetics Of A Single Dose Of Digoxin

Healthy

United States
Puma Biotechnology, Inc.

Completed

HKI-272 Ketoconazole Drug Interaction Study

Healthy
Puma Biotechnology, Inc.

Completed

Study to Examine the Effect of HKI-272 on Rhythms of the Heart (Cardiac Repolarization)

Breast Cancer

United States
Puma Biotechnology, Inc.

Completed

Study Evaluating Oral Administrations of HKI-272 in Healthy Male Subjects

Healthy

Search clinical trials for: PUMA

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