Search clinical trials for: SYK inhibitor

Total 381597 results

The Christie NHS Foundation Trust
University of Liverpool; University of Manchester

Not yet recruiting

Circulating Tumour DNA Guided Adaptive BRAF and MEK Inhibitor Therapy (DyNAMIc)

Melanoma
Shanghai Jiaolian Drug Research and Development...
Shanghai Pharmaceuticals Holding Co., Ltd

Not yet recruiting

A Clinical Study of B007 in the Treatment of Primary Membranous Nephropathy.

Primary Membranous Nephropathy

China
GlaxoSmithKline
iTeos Therapeutics

Recruiting

A Study of Belrestotug Plus Dostarlimab Compared With Placebo Plus Pembrolizumab in Previously Untreated Participants With Programmed Death Ligand 1 (PD-L1) High Non-small-cell Lung Cancer (NSCLC)

Lung Cancer, Non-Small Cell

Argentina, Belgium, Brazil, Canada, Finland, Germany, Italy, Japan, Mexico, Panama, Spain, Taiwan, Turkey, Poland, Netherlands, Korea, Republic of, France, Greece, Bulgaria, Croatia, Czechia, Estonia, Hong Kong, Hungary, India, Philippines, Portuga... and more
Soligenix

Not yet recruiting

Confirmatory Study of Topical HyBryte™ vs. Placebo for the Treatment of CTCL (FLASH2)

Mycosis Fungoides | Cutaneous T Cell Lymphoma | CTCL | CTCL/ Mycosis Fungoides
Seoul National University

Not yet recruiting

Thoracic Sympathetic Ganglion Block With Botulinum Toxin Type A

Complex Regional Pain Syndromes
Zaparackas and Knepper LTD
Northwestern University Feinberg School of Medicine

Not yet recruiting

RQC for the Prevention of Alzheimer's Disease and Retinal Amyloid-β

Alzheimer Disease | Mild Cognitive Impairment | Cognitive Decline

United States
Chinese PLA General Hospital

Recruiting

A Phase ll Trial of the Combination of Zanubrutinib, Rituximab and Venetoclax in Patients With Previously Untreated Follicular Lymphoma (ZARAV)

Ann Arbor Stage II Follicular Lymphoma | Ann Arbor Stage III Follicular Lymphoma | Ann Arbor Stage IV Follicular Lymphoma | Grade 1 Follicular Lymphoma | Grade 2 Follicular Lymphoma | Grade 3a Follicular Lymphoma

China
Zhiyong Huang
Hubei Cancer Hospital; Wuhan Union Hospital, China; Renmin Hospital of Wuhan... and other collaborators

Recruiting

Palliative Hepatectomy Combined With Targeted Therapy and Immunotherapy for Advanced Hepatocellular Carcinoma

Advanced Hepatocellular Carcinoma

China
The First Affiliated Hospital with Nanjing Medical...
Jiangsu Hengrui Pharmaceuticals Co.,Ltd

Not yet recruiting

To Evaluate the Efficacy of Adebrelimab Combined With Chemotherapy After HIFU Induction Neoadjuvant Therapy HR+/HER2- Breast Cancer

Breast Cancer | HR+/HER2- Breast Cancer
University of California, San Francisco
Merck Sharp & Dohme LLC; Astellas Pharma Inc

Not yet recruiting

Enfortumab Vedotin and Pembrolizumab Combined With Radiotherapy in Muscle Invasive Bladder Cancer

Bladder Cancer | Muscle-Invasive Bladder Carcinoma | Stage IIIA Bladder Cancer AJCC v8 | Stage II Bladder Cancer AJCC v8

United States
Institut Cancerologie de l'Ouest

Not yet recruiting

Corticodependent or Corticoresistant Brain Radionecrosis After Radiotherapy for Brain Metastases (BRADI)

Brain Metastases | Radionecrosis of Brain

France
Navy General Hospital, Beijing

Not yet recruiting

CHG Combined With Venetoclax and Azacytidine in Newly Diagnosed AML

Acute Myeloid Leukemia

China
Merck Sharp & Dohme LLC

Not yet recruiting

Substudy 06C: A Study of Sacituzumab Tirumotecan (MK-2870) With Pembrolizumab (MK-3475) and Chemotherapy in Participants With First-Line Locally Advanced Unresectable/Metastatic Gastroesophageal Adenocarcinoma (MK-3475-06C/KEYMAKER-U06)

Esophageal Cancer | Esophageal Neoplasms | Gastroesophageal Adenocarcinoma | Gastroesophageal Junction
Navy General Hospital, Beijing

Not yet recruiting

VA Conditioning Regimen Allo-HSCT for Elderly Higher-risk MDS

Higher-risk Myelodysplastic Syndromes

China
University Hospital, Montpellier

Not yet recruiting

Specific Biomarkers of Immune-mediated Hepatitis Secondary to Immune Checkpoint Inhibitors (Pro-CHILI)

Immune-mediated Hepatitis

France
Ohio State University
Patient-Centered Outcomes Research Institute; Northwestern University; Preeclampsia...

Not yet recruiting

Effectiveness of Two Aspirin Doses for Prevention of Hypertensive Disorders of Pregnancy: ASPIRIN TRIAL (ASPIRIN)

Preeclampsia | Gestational Hypertension | Hypertensive Disorders of Pregnancy

United States
Chang Gung Memorial Hospital

Not yet recruiting

Efficacy and Safety of Hydroxychloroquine in the Treatment of Sudden Sensorineural Hearing Loss

Sudden Hearing Loss
Tang-Du Hospital

Recruiting

Study on the Therapeutic Effect of Irinotecan Liposomes in Small Cell Lung Cancer

Small Cell Lung Cancer

China
University of East Anglia
Clinical Research and Trials Unit (Norfolk & Norwich University Hospital,...

Recruiting

The Role of SGLT2i in Management of Moderate AS

Moderate Aortic Valve Stenosis

United Kingdom
National Aeronautics and Space Administration (NASA)

Recruiting

Effect of Sex on Orthostatic Intolerance and Cardiovascular Response During Lunar Descent and Ascent (Lunar OI)

Healthy

United States
Regeneron Pharmaceuticals

Not yet recruiting

A Study to Learn if 27T51, a Mucin-16 (MUC16) Protein Targeting Immune Cell Therapy, Administered Alone or in Combination is Safe and How Well it Works for Adult Participants With Recurrent or Treatment Resistant Ovarian Cancers

Fallopian Tube Cancer | Epithelial Ovarian Cancer | Primary Peritoneal Carcinoma

United States
The First Affiliated Hospital with Nanjing Medical...

Recruiting

NALIRIFOX as Induction Therapy in LAPC

Pancreatic Ductal Adenocarcinoma

China
Radboud University Medical Center

Not yet recruiting

Methylphenidate in KBG Syndrome: N-of-1 Series (KBGS_N_of_1)

ADHD - Combined Type | Kbg Syndrome
Second Affiliated Hospital, School of Medicine,...

Not yet recruiting

Efficacy and Safety of Dupilumab in Combination With Tofacitinib in Moderate to Severe Adult AD Patients

Atopic Dermatitis
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

IcoSApent ethyL to Slow Down Aortic VAlve Stenosis proGrEssion (SALVAGE)

Aortic Valve Stenosis

Netherlands
Kerry Rogers

Not yet recruiting

Pirtobrutinib (LOXO-305) and Venetoclax for the Treatment of Patients With CLL or SLL Resistant to Covalent BTKi

Chronic Lymphocytic Leukemia | Small Lymphocytic Lymphoma

United States
David Ilan Sandberg

Not yet recruiting

Fourth Ventricular Administration of Immune Checkpoint Inhibitor (Nivolumab) and Methotrexate or 5-Azacytidine for Recurrent Medulloblastoma, Ependymoma, and Other CNS Malignancies

Recurrent Ependymoma | Recurrent Medulloblastoma | CNS Malignancies

United States
Institut de Recherches Internationales Servier
Servier Bio-Innovation LLC

Not yet recruiting

Ivosidenib (IVO) Monotherapy and Azacitidine (AZA) Monotherapy in Patients With Hypomethylating Agent (HMA) Naive Myelodysplastic Syndromes (MDS) With an IDH1 Mutation (PyramIDH)

Myelodysplastic Syndromes (MDS) | Hypomethylating Agent (HMA) Naive Myelodysplastic Syndromes (MDS)
Stefano Vicari
Italian Institute of Technology (IIT)

Recruiting

Efficacy of Bumetanide to Improve Cognitive Functions in Down Syndrome

Down Syndrome

Italy
TC Erciyes University

Not yet recruiting

Comparing Inhalation and Total Intravenous Anesthesia Methods

Hernia, Inguinal | Children

Turkey
Gruppo Oncologico Italiano di Ricerca Clinica

Recruiting

AGNOSTIC THERAPY IN A PHASE II SINGLE-ARM STUDY IN FIRST-LINE TREATMENT OF DURVALUMAB IN ASSOCIATION WITH CARBOPLATIN OR CISPLATIN AND ETOPOSIDE IN PATIENTS AFFECTED BY EXTENSIVE STAGE - EXTRAPULMONARY SMALL CELL CARCINOMA (DURVASCC)

Extrapulmonary Small Cell Carcinoma

Italy
Milton S. Hershey Medical Center
Aminex Therapeutics, Inc.

Not yet recruiting

Difluoromethylornithine (DFMO) and AMXT-1501 for Neuroblastoma, CNS Tumors, and Sarcomas

Ewing Sarcoma | Embryonal Tumor With Multilayered Rosettes | Osteosarcoma Recurrent | Atypical Teratoid/Rhabdoid Tumor | DIPG Brain Tumor | Neuroblastoma Recurrent
Nanjing IASO Biotechnology Co., Ltd.

Recruiting

A Phase III Study of Eque-cel in Subjects With Len-refractory RRMM (FUMANBA-03) (FUMANBA-03)

Multiple Myeloma

China
Wuhan University

Not yet recruiting

A Real-World Study of Neoadjuvant/Conversion Therapy for Locally Advanced or Metastatic Gastric Cancer

Gastric Cancer

China
Pfizer

Not yet recruiting

A Study to Learn About the Study Medicine PF-07220060 Together With Letrozole Compared to Letrozole Alone in Women Post Menopause

Breast Cancer
The First Affiliated Hospital of Henan University...

Not yet recruiting

Adebrelimab in Combination With Apatinib and Chemotherapy/Chemoradiotherapy in Immuno-experienced Second-line ESCC.

Esophageal Cancer

China
Wen-huo Chen

Recruiting

Endovascular Treatment for Mild Ischemic Stroke Due to Acute Large Vessel Occlusion in the Anterior Circulation (Mild-MT)

Mild Stroke | Endovascular Treatment

China
Genelux Corporation
Newsoara Biopharma Co., Ltd.

Not yet recruiting

Efficacy & Safety of Olvimulogene Nanivacirepvec & Platinum-doublet + Physician's of Choice Immune Checkpoint Inhibitor Compared to Docetaxel in NSCL Cancer (VIRO-25) ((VIRO-25))

Non-small Cell Lung Cancer Stage III | Non-small Cell Lung Cancer | Advanced Non-squamous Non-small-cell Lung Cancer | Non-small Cell Lung Cancer Stage IV | Metastatic Squamous Non-Small Cell Lung Carcinoma | Non-small Cell Lung Cancer Recurrent | Metastatic Non-squamous Non Small Cell Lung Cancer and other conditions
University Hospital, Strasbourg, France

Recruiting

Optimizing the Management of Sickle Cell Patients on Hydroxyurea: The Value of Therapeutic Pharmacological Monitoring (OPTIMDREP)

Sickle Cell Disease

France
Faeth Therapeutics
GOG Foundation

Not yet recruiting

Sapanisertib and Serabelisib (PIKTOR) With Paclitaxel, Serabelisib With Paclitaxel, and Paclitaxel Alone in Patients With Advanced/Recurrent Endometrial Cancer

Endometrial Cancer
AbbVie

Not yet recruiting

A Study to Assess Adverse Events and Change in Disease Activity Comparing Oral Upadacitinib to Subcutaneous Dupilumab in Children From 2 to Less Than 12 Years of Age With Moderate to Severe Atopic Dermatitis (Start Up)

Atopic Dermatitis
Guangzhou Medical University

Not yet recruiting

Immune Checkpoint Inhibitor Combined With Pemetrexed Intrathecal Injection for Leptomeningeal Metastasis From Solid Tumors

Leptomeningeal Metastasis

China
Zhou Chengzhi
Guangdong Provincial Hospital of Traditional Chinese Medicine; Sun Yat-sen... and other collaborators

Not yet recruiting

Liposomal Irinotecan Combination Regimen for First-line Treatment of Small Cell Lung Cancer

Small Cell Lung Cancer
University of Melbourne
Monash University; University of Adelaide; University of Sydney; The University... and other collaborators

Not yet recruiting

PLatform for Adaptive Trials In Perinatal UnitS - [Core Protocol] (PLATIPUS)

Preterm Birth
Guangzhou University of Traditional Chinese Medicine
Jiangsu Province Hospital of Traditional Chinese Medicine; The First Affiliated...

Not yet recruiting

Acupuncture for Enhancing Immunotherapy in Advanced NSCLC：a Pilot Study

Non-small Cell Lung Cancer | Non-Small-Cell Lung Carcinoma

China
Guangzhou Medical University

Not yet recruiting

Sacituzumab Govitecan and Intrathecal Chemotherapy for Treating Leptomeningeal Metastases From Her2-negative Breast Cancer

Leptomeningeal Metastases
Stanford University
Janssen, LP

Not yet recruiting

Talquetamab & Lenalidomide as Post Stem Cell Transplant Maintenance in Multiple Myeloma

Multiple Myeloma | Post Stem Cell Transplant

United States
Chen Xiaoping

Recruiting

Precision Treatment of Unresectable HCC Guided by Multi-omics Deep Learning Models

HCC | Precision Therapy

China
Shanghai Yueyang Integrated Medicine Hospital

Not yet recruiting

Clinical Study of Trilinolein Cream for Prevention of Relapse in Remission of Moderate-to-severe Atopic Dermatitis.

Atopic Dermatitis
Merck Sharp & Dohme LLC
GOG Foundation; European Network of Gynaecological Oncological Trial Groups...

Not yet recruiting

A Study to Compare Sacituzumab Tirumotecan (MK-2870) Monotherapy Versus Treatment of Physician's Choice as Second-line Treatment for Participants With Recurrent or Metastatic Cervical Cancer (MK-2870-020/TroFuse-020/Gog-3101/ENGOT-cx20)

Cervical Cancer

Search clinical trials for: SYK inhibitor

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