Search clinical trials for: Sirolimus

Total 1215 results

IGLESIAS Juan Fernando
Clinical Trials Unit University of Bern

Not yet recruiting

STEMI Treated With a Polymer-free Sirolimus-coated Stent and P2Y12 Inhibitor-based SAPT Versus Conventional DAPT (STARS DAPT)

ST Elevation Myocardial Infarction

Switzerland
Nader Sanai
Barrow Neurological Institute; Ivy Brain Tumor Center

Recruiting

Superselective Intra-arterial Cerebral Infusion of Temsirolimus in HGG

Glioma | Glioblastoma | High Grade Glioma | Glioma, Malignant

United States
Peking University International Hospital

Not yet recruiting

Study of Sirolimus in IgG4-related Disease

IgG4-related Disease
Beijing Tiantan Hospital
Alain Medical (Beijing) Co., Ltd.

Recruiting

Evaluating the Safety and Efficacy of the Maurora® DES in ICAS (Maurora ICAS)

Intracranial Arteriosclerosis | Stroke (CVA) or TIA

China
Terumo Europe N.V.

Recruiting

Ultimaster Nagomi™ Sirolimus Eluting Coronary Stent System in Complex PCI Patients (NAGOMI COMPLEX)

Cardiovascular Disease | Ischemic Heart Disease | Coronary Artery Occlusion

Switzerland, Spain, Netherlands, Belgium, United Kingdom, Ireland, Italy, Estonia
Aadi Bioscience, Inc.

Recruiting

Dose-escalation Study to Assess Safety and Pharmacokinetics of Nab-Sirolimus in Patients With Locally Advanced or Metastatic Solid Tumors and Moderate Liver Impairment

Advanced Solid Tumor | Tumor | Tumor, Solid

United States
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Recruiting

A Study of Safety and Efficacy of Sirolimus for Injection (Albumin-bound) in Patients With Advanced Malignant Perivascular Epithelioid Cell Tumor (PEComa)

Advanced Malignant Perivascular Epithelioid Cell Tumor (PEComa)

China
Peking University People's Hospital

Recruiting

Low-dose Interleukin-2 and Rapamycin on sjögren's Syndrome

Sjögren's Syndrome

China
Columbia University

Recruiting

Bile Acids in Acute Insulin Resistance

Cancer | Insulin Resistance | MTOR Gene Mutation | PI3K Gene Mutation | AKT Gene Mutation

United States
SWOG Cancer Research Network
National Cancer Institute (NCI)

Recruiting

Comparing Combinations of Drugs to Treat Newly Diagnosed Multiple Myeloma (NDMM) When a Stem Cell Transplant is Not a Medically Suitable Treatment

Plasma Cell Myeloma

United States
Federal Research Institute of Pediatric Hematology...

Recruiting

Efficacy and Safety of Sirolimus in Children and Adolescents With Juvenile Nasopharyngeal Angiofibroma (JNA)

Juvenile Nasopharyngeal Angiofibroma

Russian Federation
Biotronik AG
Biotronik AG

Not yet recruiting

Safety and Clinical Performance of the DREAMS 3G Resorbable Magnesium Scaffold System (BIOMAG-II)

Myocardial Ischemia | Coronary Artery Disease | Angina Pectoris | Acute Coronary Syndrome | Ischemic Heart Disease | Atherosclerosis, Coronary
Katarzyna Kotulska

Recruiting

Placebo Controlled Study to Assess the Efficacy and Safety of Rapamycin in Drug Resistant Epilepsy Associated With Tuberous Sclerosis Complex (RaRE-TS)

Tuberous Sclerosis Complex

Poland
First Affiliated Hospital Xi'an Jiaotong University
Nanjing First Hospital, Nanjing Medical University; Beijing Tongren Hospital; People's Hospital of Xinjiang Uygur Autonomous Region and other collaborators

Not yet recruiting

Rapamycin Plus Methylprednisolone Versus Methylprednisolone Alone in Active, Moderate-to-severe Graves' Orbitopathy.

Graves Ophthalmopathy

China
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Not yet recruiting

A Study of Sirolimus for Injection (Albumin-bound) in Patients With Advanced Solid Tumors

Malignant Solid Tumors
Prevail Therapeutics
Eli Lilly and Company

Recruiting

A Clinical Trial of PR001 (LY3884961) in Patients With Peripheral Manifestations of Gaucher Disease (PROCEED)

Gaucher Disease | Gaucher Disease, Type 1

United States, Spain, Germany
Fondazione Evidence per Attività e Ricerche Cardiovascolari...

Recruiting

AnGiographic Performance With A Sirolimus-elutiNG Balloon in the TrEatment of De Novo CoronaRy Artery Disease (GINGER)

Coronary Restenosis

Italy
National Institute of Allergy and Infectious Diseases...

Recruiting

Allogeneic Hematopoietic Stem Cell Transplantation for Chronic Granulomatous Disease (CGD) With an Alemtuzumab, Busulfan and TBI-based Conditioning Regimen Combined With Cytokine (IL-6, +/- IFN-gamma) Antagonists

Chronic Granulomatous Disease

United States
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Sirolimus in Cutaneous Sarcoidosis (SIRIUS)

Sarcoidosis | Cutaneous Sarcoidosis
University Hospital, Essen

Recruiting

Vascular Effects Through Sirolimus vs. Paclitaxel DCB Implantation

Peripheral Arterial Disease | Drug Eluting Balloon | Infrainguinal Peripheral Arterial Disease | Flow-mediated Dilation

Germany
Samsung Medical Center
Genoss Company Limited, Suwon, Korea

Recruiting

GENOSS Coronary Stent Clinical Trial

Ischemic Heart Disease

Korea, Republic of
National Cancer Institute (NCI)

Recruiting

The Lowest Effective Dose of Post-Transplantation Cyclophosphamide in Combination With Sirolimus and Mycophenolate Mofetil as Graft-Versus-Host Disease Prophylaxis After Reduced Intensity Conditioning and Peripheral Blood Stem Cell Transplantation

Hematopoietic Stem Cell Transplantation | Peripheral Blood Stem Cell Transplantation

United States
Vascular Therapies, Inc.

Recruiting

A Study Testing the Use of a Perivascular Sirolimus Formulation (Sirogen) in ESRD Patients Undergoing AV Fistula Surgery (ACCESS2)

End Stage Renal Disease | ESRD | End Stage Kidney Disease | Arteriovenous Fistula | Vascular Access Complication | Chronic Kidney Failure | Complication of Hemodialysis | Complication of Renal Dialysis

United States, United Kingdom
The Hospital for Sick Children
Thalassemia Foundation of Canada

Recruiting

Thal-Fabs: Reduced Toxicity Conditioning for High Risk Thalassemia

Thalassemia in Children

Canada
Meril Life Sciences Pvt. Ltd.

Not yet recruiting

Non-inferiority Clinical Trial to Compare the Safety and Performance of MeRes100 Sirolimus-eluting BioResorbable Vascular Scaffold System Versus Contemporary DES Platforms in Patients With de Novo Coronary Artery Lesions (MeRethonRCT)

Coronary Artery Disease
University of Nottingham
University of Oxford

Recruiting

Impacts of Mechanistic Target of Rapamycin (mTOR) Inhibition on Aged Human Muscle (Rapamune) (Rapamune)

Muscle Atrophy | Age-Related Sarcopenia

United Kingdom
REVA Medical, Inc.

Recruiting

MOTIV BTK Randomized Controlled Trial

Critical Limb Ischemia

United States, Germany
University of Missouri-Columbia

Recruiting

Short Term Sirolimus Treatment and MRI of the Brain

Genetic Predisposition to Disease | Healthy Volunteers

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

TMLI and Alemtuzumab for Treatment of Sickle Cell Disease

Sickle Cell Disease

United States
National Taiwan University Hospital
M.A. Med Alliance S.A.

Recruiting

Selution Sirolimus-eluting Balloon for Internal Pudendal-penile Artery Disease-related Erectile Dysfunction

Peripheral Arterial Disease | Erectile Dysfunction | Arterial Stenosis

Taiwan
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Addition of JSP191 (C-kit Antibody) to Nonmyeloablative Hematopoietic Cell Transplantation for Sickle Cell Disease and Beta-Thalassemia

Sickle Cell Anemia | Beta Thalassemia

United States
Children's Hospital of Fudan University

Recruiting

The Effect of Sirolimus on Immunizations During the Treatment of Kaposiform Hemangioendothelioma

Kaposiform Hemangioendothelioma

China
Singapore General Hospital

Recruiting

A Real-world Registry Investigating Sirolimus-coated Balloon Versus Paclitaxel-coated Balloon Angioplasty for the Treatment of Dysfunctional Arteriovenous Fistula (SAVE AVF)

Stenosis | Dialysis Access Malfunction

Singapore
National Cancer Institute (NCI)

Recruiting

Donor Lymphocyte Infusion After Allogeneic Hematopoietic Cell Transplantation for High-Risk Hematologic Malignancies

Hematologic Neoplasms

United States
West China Hospital

Recruiting

Different Doses of Sirolimus for the Maintenance Treatment of Kaposiform Hemangioendothelioma

Hemangioendothelioma

China
Unity Health Toronto
National Institutes of Health (NIH)

Recruiting

Sirolimus for Nosebleeds in HHT

Epistaxis | Hereditary Hemorrhagic Telangiectasia | Nosebleeds

Canada
Instituto Nacional de Cardiologia Ignacio Chavez

Recruiting

Zotarolimus vs Sirolimus Eluting Stent in High Bleeding Risk (ZEVS-HBR)

Coronary Artery Disease | Percutaneous Coronary Intervention | High Bleeding Risk

Mexico
University of Texas Southwestern Medical Center

Not yet recruiting

The Role of Sirolimus in Preventing Functional Decline in Older Adults

Aging
University of Copenhagen
Danish Diabetes Academy

Recruiting

mTOR as Mediator of Insulin Sensitivity Study

Insulin Sensitivity

Denmark
Chong Kun Dang Pharmaceutical

Recruiting

Study to Compare the Efficacy and Safety After Conversion to RaparoBell® or My-Rept® in Kidney Transplant Patients

Kidney Transplantation

Korea, Republic of
Institut d'Investigació Biomèdica de Bellvitge

Recruiting

Effect of Loratadine in Lymphangioleiomyomatosis (LORALAM)

Lymphangioleiomyomatosis

Spain
Palvella Therapeutics, Inc.

Recruiting

A Multicenter, Phase 3 Randomized, Double-Blind, Vehicle-Controlled Study Evaluating the Safety and Efficacy of QTORIN 3.9% Rapamycin Anhydrous Gel in the Treatment of Pachyonychia Congenita (VAPAUS)

Pachyonychia Congenita

United States, United Kingdom
Rapa Therapeutics LLC

Recruiting

RAPA-201 Therapy of Solid Tumors

Breast Cancer | Head and Neck Cancer | Gastric Cancer | Solid Tumor | Bladder Cancer | Triple Negative Breast Cancer | Esophageal Adenocarcinoma | Esophageal Squamous Cell Carcinoma | Malignant Melanoma | Carcinoma of Unknown Primary | Squamous Cell Carcinoma of Larynx | Squamous Cell Carcinoma of Oral Cavity | Squamous Cell Carcinoma of Nasopharynx and other conditions

United States
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Recruiting

A Study of Sirolimus for Injection (Albumin Bound) in Patients With Advanced Solid Tumors

Advanced Solid Tumors

China
Masonic Cancer Center, University of Minnesota

Recruiting

PTCy + Sirolimus/VIC-1911 as GVHD Prophylaxis in Myeloablative PBSC Transplantation

Lymphoma | Myelodysplastic Syndromes | Acute Leukemia | Myeloproliferative Neoplasm

United States
Darcy Krueger

Recruiting

Stopping TSC Onset and Progression 2B: Sirolimus TSC Epilepsy Prevention Study (TSC-STEPS)

Epilepsy | Tuberous Sclerosis Complex

United States
Lepu Medical Technology (Beijing) Co., Ltd.

Not yet recruiting

Long-term Efficacy of Drug-coated Balloon Versus Drug-eluting Stent in Large de Novo Coronary Lesions

Coronary Artery Disease | Drug-coated Balloon
Palvella Therapeutics, Inc.

Recruiting

Study Evaluating the Safety and Efficacy of PTX-022 (QTORIN Sirolimus) in the Treatment of Microcystic Lymphatic Malformations

Microcystic Lymphatic Malformation

United States
Medical University of South Carolina

Recruiting

COAST Therapy in Advanced Solid Tumors and Prostate Cancer (COAST)

Prostate Cancer Recurrent | Solid Tumor, Adult

United States
General Hospital of Ningxia Medical University

Recruiting

Prophylactic Norepinephrine and Phenylephrine Infusion for Hemodynamic Effects in Patients With Preeclampsia

Hemodynamic Instability

China

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