Search clinical trials for: fasted and fed state

Total 482906 results

Ixchelsis Limited

Completed

Relative Bioavailability Study of IX-01 Caplet Versus Aqueous Dispersion and Food Effect of the Caplet in Healthy Males (IX-0106 RBA)

Healthy

United States
Janssen Research & Development, LLC

Completed

A Study to Assess the Bioequivalence of the Metformin Component of the Fixed Dose Combination Tablet of Canagliflozin and Metformin Extended Release With Respect to Metformin XR Tablet Co-administered With Canagliflozin in Healthy Fed and Fasted Participants

Healthy

United States
Janssen Research & Development, LLC

Completed

A Study to Assess the Bioequivalence of the Metformin Component of the Fixed Dose Combination Tablet of Canagliflozin and Metformin Extended Release With Respect to Metformin Extended Release Tablet Coadministered With Canagliflozin in Healthy Fed and Fasted Participants

Healthy

United States
Eli Lilly and Company

Completed

A Study of LY3023414 Formulations and the Effect of Food

Healthy

United States
Bristol-Myers Squibb

Completed

Safety Study of INX-08189, Pharmacokinetic and Pharmacodynamic With Ribavirin and Food Effect Study, in Chronically-infected Genotype 1 Hepatitis C Virus, Treatment-naïve Subjects (INH-189-006)

Hepatitis C

United States, Puerto Rico
Pain Therapeutics

Completed

Single-Dose, Crossover Study To Compare Bioavailability Of Two Formulations Under Fed And Fasted Conditions

Healthy

United States
Elan Pharmaceuticals

Completed

Comparison of Safety and Efficacy of Tizanidine Hydrochloride Capsules Versus Zanaflex® (Tizanidine Hydrochloride Tablets) Taken While in the Fed State (Just After a Meal) and in the Fasted State (Before a Meal) in Patients With Moderate to Severe Spasticity.

Stroke | Multiple Sclerosis | Muscle Spasticity | Spinal Cord Injury

United States
Mundipharma Research Limited

Completed

A Study of Whether 2 New Oral Formulations of a Strong Pain Killer Release the Same Amount of Drug Into the Body as the Marketed Medication

Pain

United Kingdom
Pfizer

Completed

Study to Evaluate Safety and Tolerability of Single Ascending Doses of Multiple Formulations of PF-06650833 in Healthy Subjects Under Fasted and Fed Conditions

Healthy

United States
AstraZeneca

Completed

Bioequivalence Study of Saxagliptin and Glucophage Combination Formulations in Healthy Subjects (A)

Type 2 Diabetes Mellitus

United States
AstraZeneca

Completed

Bioequivalence Study of 2.5-mg Saxagliptin and 500-mg Glucophage in Tablets and a Fixed-dose Combination Tablet in Healthy Participants

Type 2 Diabetes Mellitus

United States
Janssen Research & Development, LLC

Completed

Bioequivalence Study of Metformin Component of Fixed Dose Combination (FDC) Immediate Release (IR) Tablet of Canagliflozin and Metformin Compared to Metformin IR Tablet Co-administered With Canagliflozin in Healthy Fed and Fasted Participants

Bioequivalence

United States
Janssen Research & Development, LLC

Completed

Bioequivalence Study of Metformin Component of Canagliflozin and Metformin Fixed Dose Combination Immediate Release (IR) Tablet Comparing With Metformin IR Tablet Co-administered With Canagliflozin Tablet in Healthy Fed and Fasted Participants

Healthy

United States
Boehringer Ingelheim

Completed

Relative Bioavailability of Tipranavir (TPV)/Ritonavir (RTV) at Steady State Administered as Oral Solutions vs. Capsules in the Fed and Fasted State in Healthy Volunteers

Healthy
Richmond Pharmacology Limited

Completed

Food and Insulin Effect on QT/QTC Interval of ECG (C11035)

Effects of Different Meals on the QT/QTc Interval | Insulin and Oral Hypoglycemic [Antidiabetic] Drugs Causing Adverse Effects in Therapeutic Use | C-Peptide Effects on the QT/QTc Interval | Moxifloxacin ECG Profile in Fed and Fasted State | Japanese vs. Caucasian TQT Comparison

United Kingdom
Boehringer Ingelheim

Withdrawn

Relative Bioavailability of BI 691751 Administered With and Without Food to Healthy Male Subjects

Healthy

United States
Mundipharma Research Limited

Completed

A Study to Assess How the Body Processes a Strong Painkiller When it is Given Alongside a Drug That Counteracts the Side Effects of Strong Painkillers in a Fasted and Fed State.

Pain

United Kingdom
Janssen Research & Development, LLC

Completed

A Study to Assess the Effect of Food on the Bioavailability of Mebendazole From a Fast-Disintegrating Chewable Formulation of Mebendazole in Healthy Participants

Healthy

Belgium
AstraZeneca

Withdrawn

BE Study of the Fixed Dose Combination of 5 mg Saxagliptin and 500 mg Metformin HCl XR Tablet Relative to a 5 mg Saxagliptin (Onglyza™) Tablet and a 500 mg Metformin HCl XR (Glifage® XR Marketed in Brazil by Merck S.A.) Tablet Co-Administered to Healthy Subjects in the Fasted and Fed States

Type 2 Diabetes

Brazil
Pfizer

Completed

Relative Bioavailability Of Palbociclib (PD-0332991) Under Fed And Fasted Conditions

Healthy

United States
KU Leuven

Unknown

The Use of a Non-absorbable Marker for the Evaluation of the Gastrointestinal Transit

Concentration-Time Profiles in Stomach & Intestine.

Belgium
KU Leuven

Unknown

Gastrointestinal Behavior of Posaconazol in Healthy Volunteers

Healthy

Belgium
Pfizer

Completed

Characterization Of The Effect Of Food On Palbociclib (PD-0332991) Absorption

Healthy

United States
Eisai Inc.

Completed

A Single-Center, Open-Label, Randomized, 3-Treatment Crossover Bioavailability Study of Single Oral Doses of E5501 Old Tablet Formulation Under Fasted Conditions and a New Tablet Formulation Under Fed and Fasted Conditions in Healthy Subjects

Healthy Subjects

United States
New York Obesity and Nutrition Research Center
Columbia University; St. Luke's-Roosevelt Hospital Center

Unknown

Brain Activation in Response to Appetitive Cues Pre- and Post- Bariatric Surgery

Obesity

United States
Pfizer

Completed

A Study Comparing PF-06273340 Immediate Release Tablet, PF-06273340 Modified Release Tablets To PF-06273340 Oral Solution In The Fasted State. This Study Will Also Compare PF-06273340 Modified Release Tablets In Fasted And Fed State

Healthy

Singapore
AstraZeneca

Completed

Assess Pharmacokinetics of Fostamatinib in Fed and Fasted State in Combination With Ranitidine to Assess Bioavailability (PK Combination)

Pharmacokinetics

United States
Pfizer

Completed

A Study Comparing PF-05089771 TS Tablet to PF-05089771 TS Oral Dispersion In The Fasted State And To PF-05089771 TS Tablet In The Fasted And Fed State

Pain

Belgium
Trio Medicines Ltd.
Ferring Pharmaceuticals

Completed

Effect of Single Doses of YF476 on Stomach Acidity Compared With Ranitidine and Placebo in Fasted and Fed States

Reflux Oesophagitis

United Kingdom
PLx Pharma

Completed

Food-Effect Pharmacokinetic Study of PL2200

Healthy

United States
University of Valencia
University of Bologna; Hospital Universitario La Fe

Recruiting

Plant Sterols on Cardiovascular Markers, Microbiota and Sterol Metabolism (Cardiofoodsterol)

Cardiovascular Diseases | Prediabetic State | Hypercholesterolemia | Overweight and Obesity

Spain
Milton S. Hershey Medical Center
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Cardiovascular Effects of Angiotensin-(1-7) in Obesity Hypertension

Hypertension | Obesity

United States
Hanmi Pharmaceutical Company Limited

Recruiting

A Phase 1 Study to Assess HM15275 in Healthy and Obese Subjects.

Obesity

United States
Novo Nordisk A/S

Not yet recruiting

A Research Study Looking at Different Oral Formulations and the Effect of Food Intake on How the Medicine NNC0487-0111 Behaves in the Body of Participants Living With Overweight or Obesity

Obesity | Overweight

United States
Thomas J Sferra, MD

Not yet recruiting

Milk Thistle Clinical Trial in Pediatric NAFLD

Non-Alcoholic Fatty Liver Disease (NAFLD)

United States
University of Illinois at Chicago

Not yet recruiting

Time-restricted Eating Among Pregnant Females With Severe Obesity (TRE-Preg)

Obesity, Morbid | Time Restricted Eating | Pregnancy Weight Gain

United States
St. Petersburg State Pavlov Medical University

Recruiting

BeFluBu vs FluBuRux Conditioning in Haploidentical HCT

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Acute Lymphoblastic Leukemia | Lymphoblastic Lymphoma | Myeloproliferative Neoplasm | Biphenotypic Acute Leukemia

Russian Federation
University of California, Davis

Recruiting

The Influence of Chardonnay Marc Intake on Gut and Cardiometabolic Health

Cardiovascular Diseases | Adiposity | Cardiometabolic Syndrome

United States
State Budget Public Health Institution Scientific...

Recruiting

Laparoscopic Total Extraperitoneal Plasty as a Modification of Sugabecker's Operation (LTEPP)

Parastomal Hernia

Russian Federation
Amur State Medical Academy

Recruiting

The Endovascular Plus GENe Therapy Versus Only EndoVascular Therapy for Severe Limb ischaemiA Trial

Severe Lower Limb Ischemia

Russian Federation
Michelle Cardel, PhD, MS, RD

Recruiting

Medications With or Without WeightWatchers (Meds WOW-WW)

Obesity | Overweight

United States
Duke University
National Institutes of Health (NIH); National Institute on Aging (NIA)

Not yet recruiting

Role of Aging and Individual Variation in Exercise Training Responsiveness (STRRIDE IV)

Cardiovascular Diseases | Obesity | Insulin Resistance | Prediabetic State
State Scientific Centre of Coloproctology, Russian...

Not yet recruiting

Effectiveness of Artificial Intelligence - Assisted Colonoscopy in Colorectal Neoplasms (ArtInCol)

Colonic Polyp | Colonic Neoplasms | Diagnosis

Russian Federation
National Aeronautics and Space Administration (NASA)

Recruiting

Effect of Sex on Orthostatic Intolerance and Cardiovascular Response During Lunar Descent and Ascent (Lunar OI)

Healthy

United States
University of California, Davis
Knownwell

Recruiting

CRAVE Study: Comparing Craving Responses and Diet Quality of GLP1 Receptor Agonist Users

Obesity

United States
United States Army Research Institute of Environmental...

Not yet recruiting

The Effects of Semaglutide on Body Composition and Performance in Military Personnel

Obesity
Northwestern University

Not yet recruiting

Conical Forearm and Cylindrical Upper Arm Non-Invasive Blood Pressure (NIBP) Measurements in Pregnant Patients

Hypertension | Obesity | Hypertension in Pregnancy

United States
Vanderbilt University
Vanderbilt University Medical Center

Not yet recruiting

Whole Foods for Teens: A Pilot Dietary Intervention to Reduce Body Adiposity in Adolescents With Obesity

Body Weight Changes | Obesity, Childhood | Diet, Healthy

United States
Uniformed Services University of the Health Sciences
Henry M. Jackson Foundation for the Advancement of Military Medicine

Recruiting

The Effect of Omega-3 Fortified Smoothies on Omega-3 Index and Physical Performance Related Outcomes Among Soldiers (H2FO3)

Nutrition, Healthy

United States
Indiana University

Recruiting

Inspiratory Muscle Training in Postmenopausal Women (MRS)

Obesity | Aging | Postmenopausal Symptoms

United States

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