Search clinical trials for: herpes simplex virus infection

Total 57560 results

Bayer

Active, not recruiting

A Study to Compare Sitavig (Acyclovir) Buccal Tablet With a Placebo in the Treatment of Herpes Labialis in Participants Whose Immune System Works Normally

Recurrent Herpes Labialis

United States
National Cancer Institute (NCI)

Active, not recruiting

Talimogene Laherparepvec and Nivolumab in Treating Patients With Refractory Lymphomas or Advanced or Refractory Non-melanoma Skin Cancers

Sezary Syndrome | Refractory T-Cell Non-Hodgkin Lymphoma | Merkel Cell Carcinoma | Anaplastic Large Cell Lymphoma, ALK-Positive | Extramammary Paget Disease | Recurrent T-Cell Non-Hodgkin Lymphoma | Recurrent Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma | Refractory Mature T-Cell and NK-Cell Non-Hodgkin... and other conditions

United States
GlaxoSmithKline

Completed

A Study on the Reactogenicity, Safety and Immune Response of a Targeted Immunotherapy Against HSV in Healthy Japanese Participants Aged 18-40 Years (TH HSV REC-004)

Herpes Simplex

Japan
GlaxoSmithKline

Active, not recruiting

A Study on the Reactogenicity, Safety, Immune Response, and Efficacy of a Targeted Immunotherapy Against HSV in Healthy Participants Aged 18-40 Years or in Participants Aged 18-60 Years With Recurrent Genital Herpes

Herpes Simplex

Germany, United States, Belgium, Canada, Spain, United Kingdom, Estonia, Australia
King Edward Medical University

Completed

Comparison of Prophylactic Acyclovir and Placebo in Prevention of Eczema Herpeticum in Pediatric Burns (childburn)

Herpes Virus Infection

Pakistan
GlaxoSmithKline

Completed

Study to Evaluate Immunogenicity and Safety of GSK Biologicals' Herpes Zoster Subunit (HZ/su) Vaccine at 9 and 10 Years After Vaccine Administration and Assessment of Re-vaccination With 2 Additional Doses at 10 Years After Initial Vaccination, in Healthy Subjects Aged 60 Years of Age(YOA) and Older

Herpes Zoster

Germany, Czechia, Sweden
GlaxoSmithKline

Completed

A Study on the Immune Response and Safety of a Vaccine Against Herpes Zoster in Adults Aged 50 Years and Older in India

Herpes Zoster

India
ModernaTX, Inc.

Active, not recruiting

A Study of mRNA-1608, a Herpes Simplex Virus -2 (HSV-2) Therapeutic Candidate Vaccine, in Healthy Adults 18 to 55 Years of Age With Recurrent HSV-2 Genital Herpes

Genital Herpes

United States
Replimune Inc.
Regeneron Pharmaceuticals

Active, not recruiting

Study Evaluating Cemiplimab Alone and Combined With RP1 in Treating Advanced Squamous Skin Cancer (CERPASS)

Cutaneous Squamous Cell Carcinoma | Advanced Cutaneous Squamous Cell Carcinoma | Metastatic Cutaneous Squamous Cell Carcinoma

Spain, United States, France, Australia, Germany, Canada, Greece, Bulgaria, Italy, Poland
MAXVAX Biotechnology Limited Liability Company
Henan Center for Disease Control and Prevention

Active, not recruiting

Safety and Immunogenicity of Recombinant Herpes Zoster Vaccine (CHO Cells) in Healthy Subjects Aged 18 Years and Above

Herpes Zoster

China
GlaxoSmithKline

Completed

A Long-term Follow-up Study (ZOE-LTFU) of Two Studies 110390 (ZOSTER-006) and 113077 (ZOSTER-022) to Assess the Efficacy, Safety, and Immunogenicity Persistence of GSK Biologicals' Herpes Zoster Subunit (HZ/su) Vaccine and Assessment of 1 or 2 Additional Doses in Two Subgroups of Older Adults

Herpes Zoster

United States, Australia, Spain, Finland, Germany, Japan, Taiwan, Sweden, Korea, Republic of, Brazil, Mexico, Canada, Italy, France, Czechia, Estonia, Hong Kong, United Kingdom
NOWDiagnostics, Inc.

Withdrawn

NOWDx Test for the Diagnosis of Herpes Simplex Virus Type 2

Herpes Simplex Virus Infection | HSV-2 Infection

United States
GlaxoSmithKline

Active, not recruiting

An Epidemiological Study to Assess Performance of Using Healthcare Tools to Understand Genital Herpes Simplex Virus-2 (HSV-2) in Patients ≥ 18 Years of Age in the United States and Europe.

Herpes Genitalis

United States, France, Italy, Spain, Finland, United Kingdom
NYU Langone Health
National Eye Institute (NEI); National Institutes of Health (NIH)

Active, not recruiting

Zoster Eye Disease Study (ZEDS)

Herpes Zoster Ophthalmicus

United States, Canada
GlaxoSmithKline

Active, not recruiting

A Study to Evaluate the Safety and Immunogenicity of GlaxoSmithKline's Herpes Zoster Subunit Vaccine (HZ/su) When Given on a Two-dose Schedule to Adults at Least 50 Years of Age (YOA) Who Had Prior Episode of Shingles

Herpes Zoster

Spain, Panama, Mexico, Russian Federation, Finland, Estonia, Hong Kong, United Kingdom
AiCuris Anti-infective Cures AG

Completed

Potential Influence of Esomeprazole on the Pharmacokinetics of Pritelivir

HSV Infection

United States
University of Wisconsin, Madison
Boston Medical Center

Active, not recruiting

Immunogenicity of Herpes Zoster Subunit Vaccine in Inflammatory Bowel Disease Patients Treated With Vedolizumab

Inflammatory Bowel Diseases | Crohn Disease | Ulcerative Colitis | Herpes Zoster

United States
GlaxoSmithKline

Active, not recruiting

A Study on the Long-term Efficacy, Safety and Persistence of Immune Response of a Vaccine Against Herpes Zoster in Older Adults

Herpes Zoster

United States, Australia, Finland, Germany, Japan, Taiwan, Sweden, Spain, Korea, Republic of, Brazil, Mexico, Italy, Canada, Czechia, Estonia, France, Hong Kong, United Kingdom
New York State Psychiatric Institute
Alzheimer's Association

Active, not recruiting

Valacyclovir for Mild Cognitive Impairment (VALMCI)

Mild Cognitive Impairment | Herpes Simplex 2 | Herpes Simplex 1

United States
Shanghai Institute Of Biological Products
Chinese Academy of Medical Sciences Dermatology Hospital

Completed

A Study Exploring Efficacy of Peginterferon in Patients With Herpes Zoster

Herpes Zoster

China
GlaxoSmithKline

Active, not recruiting

A Study to Test GlaxoSmithKline's (GSK) Herpes Zoster (HZ) Subunit Vaccine's Long-term Immune Response in Previously Vaccinated Kidney Transplant Adults and Then to Test if 2 Additional Doses of the Vaccine Are Safe and Able to Generate an Immune Response

Herpes Zoster

Spain, Canada, Belgium, Finland, Korea, Republic of, Panama, Taiwan
AiCuris Anti-infective Cures AG
Impatients N.V. trading as myTomorrows

Available

Expanded Access Intermediate Size Treatment Protocol: Pritelivir for Immunocompromised Subjects With Treatment Resistant Herpes Simplex Virus Type 1 or 2

HSV
University of Utah

Enrolling by invitation

EDTA Eye Drops Compared to Abreva for Herpes Simplex Virus Eruptions

Herpes Simplex Oral

United States
University of Nove de Julho

Completed

Treatment of Herpes Labialis by Photodynamic Therapy (Herpes)

Photodynamic Therapy | Herpes Simplex, Labial

Brazil
Immorna Biotherapeutics, Inc.
ICON plc

Active, not recruiting

A First-in-Human Study to Evaluate JCXH-105, an srRNA-based Herpes Zoster Vaccine (JCXH-105)

Infectious Disease | Shingles | Herpes Zoster (HZ)

United States
KBio Inc
Boston University; National Institute of Allergy and Infectious Diseases (NIAID) and other collaborators

Completed

Safety Study of Monoclonal Antibodies to Reduce the Vaginal Transmission of HSV and HIV (VAST)

HIV | Herpes Simplex Infections

United States
MAXVAX Biotechnology Limited Liability Company
Henan Center for Disease Control and Prevention

Active, not recruiting

Immunogenicity and Safety of Recombinant Herpes Zoster Vaccine (CHO Cells) in Healthy Subjects Aged 30 Years and Above

Herpes Zoster

China
Iveriapharma LLC

Completed

Efficacy of Lazolex® Gel in the Treatment of Herpes Simplex

HSV Infection
Labo'Life

Terminated

Study of 2LHERP® in Genital Herpes Infections (HEARTH-GEN)

Herpes Simplex, Genital

Belgium
Nobelpharma

Completed

NPC-06 to Pain Associated With Acute Herpes Zoster

Acute Pain in Herpes Zoster

Japan
Heidelberg ImmunoTherapeutics GmbH

Terminated

Monoclonal Antibody Therapy Against Chronic Herpes Simplex Virus 1 Infection (MATCH-1)

Herpes Labialis

Germany
Daniel Benjamin
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care (PTN_POPS)

Heart Failure | Epilepsy | Pain | Pneumonia | Sepsis | Inflammation | Hypertension | Chronic Kidney Diseases | Hemophilia | Schizophrenia | Central Nervous System Infections | Nosocomial Pneumonia | Insomnia | Anxiety | Bipolar Disorder | Neutropenia | Staphylococcal Infections | Bradycardia | Seizures | Urinary Tract Infections | Pulmonary... and other conditions

United States, Canada, United Kingdom, Israel, Singapore
Curevo Inc
Green Cross Corporation; Mogam Biotechnology Research Institute

Active, not recruiting

Safety and Immunogenicity of CRV-101 Vaccine for the Prevention of Herpes Zoster in Adults Aged 50 Years and Older

Herpes Zoster | Shingles

United States
Columbia University
National Institutes of Health (NIH); National Institute on Aging (NIA)

Active, not recruiting

Anti-viral Therapy in Alzheimer's Disease

Alzheimer Disease | Herpes Simplex 2 | Herpes Simplex 1

United States
AiCuris Anti-infective Cures AG

Completed

Thorough QT/QTc of Pritelivir in Healthy Subjects

HSV Infection

United Kingdom
ModernaTX, Inc.

Active, not recruiting

A Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1468 in Healthy Adults ≥50 Years of Age

Herpes Zoster

United States, Puerto Rico
Methodist Health System

Completed

Impact of Obesity on Clinical Outcomes in Patients Receiving Acyclovir for HSV Encephalitis"

HSV Encephalitis

United States
Radboud University Medical Center
GlaxoSmithKline

Completed

Age Differences in Influenza and Herpes Zoster Vaccine Responses (INFLUENZA-SHINGRIX)

Influenza | Herpes Zoster

Netherlands
University of California, San Francisco

Completed

Evolution of Pain From Herpes Zoster

Post-Herpetic Neuralgia | Acute Herpes Zoster

United States
AiCuris Anti-infective Cures AG
Medpace, Inc.

Terminated

Safety and Efficacy Comparator Trial of a New Drug Against Genital Herpes

Genital Herpes

United States
St. Justine's Hospital
Canadian Association of Emergency Physicians

Completed

Should We Use Oral Valacyclovir in Acute Herpetic Gingivostomatitis in Children?

Herpetic Gingivostomatitis

Canada
Assistance Publique Hopitaux De Marseille

Completed

PTH - Preemptive Treatment for Herpesviridae (PTH)

Viral Pneumonia

France
Focus Consumer Healthcare
Citruslabs

Completed

An Investigation Into the Efficacy of Herpecin L at Reducing the Frequency and Severity of Cold Sores

Cold Sores

United States
University of Washington
National Institute of Allergy and Infectious Diseases (NIAID)

Terminated

Effect of HSV-2 Suppressive Therapy on Sexual Behavior

Genital Herpes

United States
Dove Medical Press Ltd
The Affiliated Hospital of Qingdao University; Nakhia Impex LLC

Completed

A Clinical Study of Freshly Manufactured 35kDa Hyaluronan Fragment in the Treatment of Pain

Back Pain | Neck Pain | Shoulder Pain | Herpes Zoster Pain | Temporal Pain

China
University of Washington
Gilead Sciences; CONRAD

Completed

Effect of Tenofovir on Genital Herpes Simplex Virus (HSV) Shedding

Herpes Simplex Type II

United States
Rational Vaccines Inc

Completed

A Study of the Characteristics of Patients Diagnosed With Recurrent Symptomatic Genital Herpetic Disease

Patient Engagement | Genital Herpes

United Kingdom
Rigshospitalet, Denmark
Statens Serum Institut

Completed

Host RNA Expression Profiles and Protein Biomarkers in Neonatal Herpes Simplex Virus Infection

Neonatal Infection | Viral Infection | Neonatal Sepsis | Neonatal Death | Herpes Simplex Virus Infection | Newborn; Infection | Neonatal Herpes Simplex Infection | Neonatal HSV Infection

Denmark
Momentum Data
Pfizer; University of Oxford; University of Surrey

Completed

The Epidemiology, Management, and the Associated Burden of Related Conditions in Alopecia Areata

Multiple Sclerosis | Pneumonia | Rheumatoid Arthritis | Systemic Lupus Erythematosus | Anxiety Disorders | Psoriasis | Asthma | Type 1 Diabetes | Graves Disease | Celiac Disease | Allergic Rhinitis | Urinary Tract Infections | Crohn Disease | Influenza | Ulcerative Colitis | Herpes Zoster | Herpes Simplex | Atopic Dermatitis | V... and other conditions

United Kingdom
Dynavax Technologies Corporation

Completed

Trial to Evaluate the Safety, Tolerability, and Immunogenicity of an Investigational Herpes Zoster Vaccine (Z-1018) Compared to Shingrix® in Healthy Adult Volunteers

Herpes Zoster | Vaccine-Preventable Diseases | Shingles

Australia

Search clinical trials for: herpes simplex virus infection

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