Search clinical trials for: high-risk stage

Total 16032 results

Daping Hospital and the Research Institute of Surgery...

Not yet recruiting

Osimertinib and Etoposide as First-Line Treatment in Osimertinib-Resistant Advanced EGFR-Mutant NSCLC

Non Small Cell Lung Cancer | Non Small Cell Lung Cancer Stage IIIB | EGFR Gene Mutation | Non-small Cell Lung Cancer Stage IV
University of British Columbia
Providence Health & Services

Not yet recruiting

Validation and Usability Study of Intermittent Electrical Simulation in Management of Pressure Injuries Stages 1 and 2 (IESPI)

Pressure Injury
University of North Carolina, Chapel Hill
National Institute of Allergy and Infectious Diseases (NIAID)

Not yet recruiting

Optimizing PrEP Regimens for Pregnant Women in Sub-Saharan Africa (O-PrEP Study) - Stage 1

Pregnancy | HIV | Prevention

Malawi, Zimbabwe
UMC Utrecht
The Netherlands Cancer Institute; Personal Genome Diagnostics (PGDx)

Recruiting

Circulating Tumor DNA Based Adjuvant Chemotherapy in Stage II Colon Cancer Patients: the MEDOCC-CrEATE Trial (CrEATE)

Recurrence | Circulating Tumor DNA | Colon Cancer Stage II

Netherlands
Cerevel Therapeutics, LLC

Recruiting

A Trial to Assess the Absorption, Metabolism, Excretion, and Mass Balance of [14C]-Darigabat After a Single Oral Dose in Healthy Male Participants

Healthy Participants

United States
Jonsson Comprehensive Cancer Center
Boston Scientific Corporation

Not yet recruiting

Yttrium-90 (Y90) Radioembolization for the Treatment of Early Stage Renal Cell Carcinoma, The RENEGADE Trial

Stage I Renal Cell Cancer | Stage II Renal Cell Cancer

United States
University of Vermont

Recruiting

Accelerated Pulmonary Rehabilitation in the Preoperative Period (PREHAB)

Chronic Obstructive Pulmonary Disease | Lung Cancer Stage I | Lung Cancer Stage III | Lung Cancer Stage II

United States
Amgen

Not yet recruiting

Pharmacokinetic Similarity Between ABP 234 and Keytruda® (Pembrolizumab) (Eucalyptus)

Early-stage Non-squamous Non-small Cell Lung Cancer (NSCLC)
University of Southern Denmark
Odense University Hospital; Sygehus Lillebaelt; Sonderborg Hospital; Esbjerg Hospital

Not yet recruiting

Clinical Biomarker of Paclitaxel-induced Peripheral Neuropathy

Chemotherapy-induced Peripheral Neuropathy
Nanfang Hospital, Southern Medical University

Not yet recruiting

PD-L1 Inhibitor Combined With Apatinib as First-line Maintenance Treatment for Extensive-stage Small Cell Lung Cancer

Small Cell Lung Cancer Extensive Stage
University of Virginia

Recruiting

Role of TXA in Patients Undergoing Breast Free Flap Reconstruction

Breast Cancer | Blood Loss, Surgical

United States
Sheba Medical Center

Recruiting

Health Coaching Telemedicine Program for Lung Transplant Candidates With End-stage Lung Disease. (HCTP)

Copd | End Stage Lung Disease

Israel
Fudan University

Recruiting

Clinical Study of T3011 Intravesical Instillation for Treatment of NMIBC Patients

Bladder Cancer

China
Sun Yat-sen University

Not yet recruiting

ctDNA-MRD Guided Consolidation Toripalimab in Stage IB-IIIA NSCLC (CONTINUE)

Lung Cancer, Nonsmall Cell
Georgiamune Inc

Recruiting

Safety and Tolerability Study of GIM-531 in Advanced Solid Tumors

Solid Tumor | Melanoma Stage IV

United States
Universidade Federal Fluminense

Recruiting

Clinical and Microbiological Evaluation of Laser Therapy in the Treatment of Periodontal Disease in Stages III and IV

Periodontitis | Periodontitis, Adult

Brazil
Roswell Park Cancer Institute

Not yet recruiting

An Investigational Scan (124I-hJAA-F11 PET/CT) for Diagnosing Lung Cancer

Stage IV Lung Cancer | Lung Non-Small Cell Carcinoma | Extensive-stage Small-cell Lung Cancer | Limited-stage Small-cell Lung Cancer | Stage IIIA Lung Cancer
China Medical University Hospital

Recruiting

Integrated Traditional Chinese and Western Medicine to Care for the Late Stage of Mild to Moderate Burns and Scalds

Burns and Scalds

Taiwan
Celgene

Not yet recruiting

A Study to Evaluate the Efficacy and Safety of Golcadomide in Combination With Rituximab in Participants With Newly Diagnosed Advanced Stage Follicular Lymphoma (GOLSEEK-2)

Lymphoma, Follicular

United States, Australia, Brazil, Canada, Chile, France, Germany, Italy, Korea, Republic of, Poland, Spain, Taiwan, United Kingdom
Zeng Jian

Recruiting

A Study Comparing Neoadjuvant Chemoimmunotherapy and Immuno-consolidationafter Compared With Immunoconsolidation After Radical Chemoradiotherapy for Stage III Potentially Resectable NSCLC

Non Small Cell Lung Cancer

China
Memorial Sloan Kettering Cancer Center

Recruiting

A Registry for People With Lung Cancer

Lung Cancer | Lung Cancer Stage I

United States
Emory University
National Cancer Institute (NCI)

Not yet recruiting

Gemcitabine, Cisplatin and Nab-Paclitaxel as Neoadjuvant Treatment for Patients With Resectable or Borderline Resectable Pancreatic Cancer

Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage I Pancreatic Cancer AJCC v8 | Resectable Pancreatic Adenocarcinoma | Borderline Resectable Pancreatic Ductal Adenocarcinoma

United States
University of Vienna

Not yet recruiting

PRObing The Efficacy of Commercial Stage Storage Buffers and Evaluating Gut Metaproteome Variability Between Individuals (PROTEGI)

Gut Microbiome | Fecal Microbiota | Variability | Methodology Study | Buffer

Austria
Zhujiang Hospital

Recruiting

Effects of TRE With Lactobacillus Plantarum LP-KFY04 Supplementation on Overweight / Obese Individuals (TRELO)

Obesity

China
National Cancer Institute (NCI)

Not yet recruiting

Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas

Undifferentiated Pleomorphic Sarcoma | Stage III Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8 | Stage IV Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8
University of Southern California
National Cancer Institute (NCI)

Not yet recruiting

Access to Genetic Testing in Underserved Patients With Cancer

Malignant Solid Neoplasm | Breast Carcinoma | Metastatic Prostate Carcinoma | Ovarian Carcinoma | Triple-Negative Breast Carcinoma | Male Breast Carcinoma | Pancreatic Exocrine Neoplasm | Stage IVB Prostate Cancer American Joint Committee on Cancer v8

United States
Merit Medical Systems, Inc.

Not yet recruiting

Observational Study of the Merit HeRO® Graft and Super HeRO® in Patients on Hemodialysis (PReSeRVE-HD)

End Stage Renal Disease | Hemodialysis Access Failure
European Institute of Oncology

Not yet recruiting

Efficacy and Safety of HILOTERM® Device for the Prevention of Peripheral Neuropathy

Breast Cancer | Neuropathy;Peripheral

Italy
Mayo Clinic

Recruiting

NXP800 for the Treatment of Patients With Advanced or Metastatic Cholangiocarcinoma

Stage III Intrahepatic Cholangiocarcinoma AJCC v8 | Metastatic Cholangiocarcinoma | Refractory Cholangiocarcinoma | Stage III Hilar Cholangiocarcinoma AJCC v8 | Stage IV Hilar Cholangiocarcinoma AJCC v8 | Stage IV Intrahepatic Cholangiocarcinoma AJCC v8 | Advanced Cholangiocarcinoma

United States
Marmara University

Recruiting

Immunological Parameters Between MRONJ Stages

Medication-Related Osteonecrosis of Jaw

Turkey
Medical University of Vienna

Recruiting

Vienna Hypothermic Oxygenated Machine Perfusion Study (VIHOMPS)

End Stage Liver Disease | Hepatocellular Carcinoma

Austria
First Affiliated Hospital of Chongqing Medical...

Recruiting

99mTc-QULIC-5-P1 SPECT Imaging in Patients With Prostate Cancer

PSMA | Prostate Cancer Stage | SPECT

China
Umm Al-Qura University

Recruiting

Comparative Effectiveness of Different Drugs Used to tr€at Patients in Rheumatoid Arthritis Saudi Database (RASD)"

Rheumatoid Arthritis RA

Saudi Arabia
Roswell Park Cancer Institute

Recruiting

An Education and Navigation Support Tool to Improve Participation in Care Coordination Among Patients With Locally Advanced, Metastatic and Unresectable Bladder Cancer and Their Caregivers

Stage III Bladder Cancer AJCC v8 | Stage IV Bladder Cancer AJCC v8 | Metastatic Bladder Carcinoma | Locally Advanced Bladder Carcinoma | Unresectable Bladder Carcinoma

United States
Ospedale San Raffaele

Recruiting

Genetics in the Progression of Nephropathies

Hypertension | AKI | CKD | Hematologic Malignancy | Ckd-Mbd | ADPKD | Bone Marrow Transplant Complications | CKD (Chronic Kidney Disease) Stage 5D

Italy
Fox Chase Cancer Center
University of South Carolina; Temple University; Thomas Jefferson University; Rutgers...

Not yet recruiting

Reducing Urban Cervical Cancer Disparities

Cervical Cancer | Papilloma Viral Infection

United States
Women's Hospital School Of Medicine Zhejiang University

Recruiting

Prospective Study for Endometrial Carcinoma and Hyperplasia in Childbearing-age Women

Endometrial Hyperplasia | Endometrial Cancer Stage I

China
University Health Network, Toronto

Not yet recruiting

Psilocybin-assisted Existential, Attachment and RelationaL (PEARL) Therapy for Patients With Advanced Cancer

Advanced Cancer | Stage IV Melanoma | Endocrine Cancer | Stage IV Lymphoma | Stage IV Solid Tumor Cancer | Stage IV Sarcoma of Bone

Canada
Osel, Inc.
City of Hope Comprehensive Cancer Center; Miyarisan Pharmaceutical Co., Ltd.

Recruiting

Dose Finding Study of CBM588 in Combination With Nivolumab/Ipilimumab in Advanced Stage Renal Cell Carcinoma

Advanced or Metastatic Renal Cell Carcinoma

United States
Tarsus University

Not yet recruiting

Effect of Placenta Delivery Method on Pain, Bleeding and Comfort

Placenta Abruptio

Turkey
Mario Negri Institute for Pharmacological Research

Not yet recruiting

Blood Flow Conditions and Sounds in AVFs (APOLLO)

End Stage Renal Disease

Italy
Sidney Kimmel Comprehensive Cancer Center at Johns...
Agenus Inc.; Private Philanthropic Funds

Not yet recruiting

KRAS-Targeted Vaccine Combined With Balstilimab and Botensilimab for Patients With Stage IV MMR-p Colorectal Cancer and Pancreatic Ductal Cancer

Colorectal Cancer | Pancreatic Cancer

United States
Sun Yat-sen University

Recruiting

Safety & Efficacy of Peg-ASP-based CCRT in Early Stage ENKTL (ENKTL)

Extranodal NK/T-cell Lymphoma

China
Icahn School of Medicine at Mount Sinai
National Cancer Institute (NCI)

Recruiting

Enhancing Access to Supportive Services for Women of Color With Metastatic Breast Cancer (ACCESS)

Metastatic Breast Cancer | Stage IV Breast Cancer AJCC V7

United States
University of Cologne

Recruiting

Regulation of Extracellular Sodium in End Stage Renal Disease Upon Volume and Electrolyte Challenges (RESERVE)

Hyponatremia

Germany
University Hospital Heidelberg

Recruiting

Predicting Esophageal Cancer Borders Using PET-Imaging (PEGASUS)

Esophagus Cancer, Stage I | Esophagus Cancer, Stage II

Germany
European Organisation for Research and Treatment...

Not yet recruiting

Improvement of Quality of Life Through Supportive Treatments for Hormone Therapy - Related Symptoms in Women With Early Breast Cancer

Musculoskeletal Pain | Drug-Related Side Effects and Adverse Reactions | Breast Cancer Stage I | Breast Cancer Stage II | Breast Cancer Stage III | HER2-negative Breast Cancer | ER+ Breast Cancer
Guangdong Provincial People's Hospital

Recruiting

Pulmonary Watershed Topographic Map Navigation for Lung Nodule Resection

NSCLC, Stage I | Disease Free Survival | Pulmonary Function Assessment

China
Cancer Institute and Hospital, Chinese Academy...

Not yet recruiting

A Multicentre Prospective Cohort Study: Intensive Adjuvant Therapy for TNBC With BRCA Gene Mutation

Early-stage Triple-negative Breast Cancer With BRCA1/2 Mutations

China
Maastricht University Medical Center
Gilead Sciences

Not yet recruiting

Sacituzumab Govitecan and Bevacizumab for NSCLC Brain Metastases

NSCLC Stage IV | Brain Metastases, Adult

Netherlands

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