Search clinical trials for: multiple ascending dose healthy volunteers

Total 56202 results

SoftOx Solutions AS

Completed

Safety of Ascending Single and Multiple Doses of Nebulised SoftOx Inhalation Solution in Healthy Subjects

Healthy Volunteers | Safety

Denmark
Vigonvita Life Sciences

Completed

Safety and Pharmacokinetics Study of Multiple Ascending Doses of VV116 in Healthy Volunteers

Healthy Subjects

China
Annexon, Inc.
Nucleus Network Ltd

Completed

A Single and Multiple Ascending Dose Study of ANX009 in Normal Healthy Volunteers (NHV)

Safety and Tolerability in Healthy Volunteers

Australia
Bridge Biotherapeutics, Inc.
KCRN Research, LLC

Completed

First-In-Human Study of BBT-401-1S Following Single and Multiple Ascending Doses in Healthy Volunteers

Ulcerative Colitis

United States
CymaBay Therapeutics, Inc.

Completed

Study Investigating the Safety, Tolerability, and PK, PD, of CB-0406

Healthy Volunteers

Australia
Shanghai Zhimeng Biopharma, Inc.

Completed

A Study of Orally Administered ZM-H1505R to Evaluate Safety, Tolerability and Pharmacokinetics After Single and Multiple Ascending Doses in Healthy Participants

Healthy Volunteers

United States
AstraZeneca
Parexel

Completed

A Study to Assess the Effect AZD4831 in Japanese and Chinese Healthy Volunteers

Heart Failure With Preserved Ejection Fraction (HFpEF)

United States
Galecto Biotech AB

Completed

A First in Human Study to Evaluate the Safety, Tolerability and PK of GB1211 in Healthy Subjects

Safety and Tolerability

United Kingdom
Shire

Completed

A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Ascending, Subcutaneous, Single and Multiple Doses of SHP681 (Glucagon-like Peptide-2 [GLP-2] Analog-Fc Fusion) in Healthy Adult Participants

Healthy Volunteers

United States
Biogen

Completed

Multiple Dose Study Of BIIB118 (PF-05251749) In Healthy Volunteers

Healthy Adult Subjects | Healthy Elderly Subjects

United States
Theravance Biopharma

Completed

SAD and MAD Study to Evaluate Safety, Tolerability, and Pharmacokinetics (PK) of TD-1473 in Healthy Subjects

Healthy

United States
Arthrosi Therapeutics

Completed

Multiple Ascending Dose Study of AR882 in Healthy Adult Male Volunteers

Healthy Volunteers

Australia
Lee's Pharmaceutical Limited

Unknown

An Ascending, Multiple-Dose, Safety and Tolerability Study of Tecarfarin in Healthy Chinese Volunteers

Healthy Chinese Volunteers

China
Crinetics Pharmaceuticals Inc.

Completed

A Single and Multiple-Ascending Dose Study of CRN01941 in Healthy Adult Volunteers

Healthy Volunteers

Australia
GeNeuro Australia PTY Ltd

Completed

Single Ascending Doses Study With GNbAC1 in Healthy Male Volunteers

Multiple Sclerosis

Australia
Future Medicine

Completed

A SAD, MAD, and FE Study to Evaluate the Safety, Tolerability, and Pharmacokinetic Profile of FM101 in Healthy Volunteers

Healthy Subjects

Netherlands
Sihuan Pharmaceutical Holdings Group Ltd.

Completed

A Multiple Ascending High Dose Pharmacology Study of Anaprazole in Healthy Chinese Subjects

Healthy Volunteers

China
Sihuan Pharmaceutical Holdings Group Ltd.

Completed

A Multiple Ascending Dose Pharmacology Study of Anaprazole in Healthy Chinese Subjects

Healthy Volunteers
Jiangsu Sinorda Biomedicine Co., Ltd

Completed

Single-dose and Multiple-dose X842 Phase 1 Study

Healthy Volunteers

China
JW Pharmaceutical

Completed

Single and Multiple Ascending Dose Study of JW1601 for Healthy Volunteers

Healthy

Korea, Republic of
Entasis Therapeutics

Completed

A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics (PK, the Measure of How the Human Body Processes a Substance) of ETX0282 When Administered Orally to Healthy Participants

Healthy Volunteers

Australia
National Institute of Allergy and Infectious Diseases...

Completed

Multiple Ascending Dose Study of Oxfendazole in Healthy Adult Volunteers

Helminthic Infection

United States
Alios Biopharma Inc.

Completed

A Study of Orally Administered JNJ-440 to Evaluate the Safety, Tolerability, and Pharmacokinetics After Single Ascending Doses Including Food Effect Evaluation; After Multi-Day Dosing in Healthy Participants; and After Multiple (Ascending) Doses in Participants With Chronic Hepatitis B

Chronic Hepatitis B

Korea, Republic of, Moldova, Republic of, New Zealand, Thailand, Ukraine
Neurop Inc.
National Institute of Neurological Disorders and Stroke (NINDS); Pharmaron

Completed

A Multiple Ascending Dose Study of Safety and Pharmacokinetics of NP10679 in Normal Healthy Volunteers

Pain, Postoperative | Subarachnoid Hemorrhage | Stroke, Ischemic | Substance Abuse

United States
Inventiva Pharma
Parexel

Completed

Multiple Ascending Dose Phase I Study in Order to Define Lanifibranor (IVA337) Supra-thjerapeutic Dose (MAD)

Healthy Subjects

Germany
Genentech, Inc.

Terminated

A Study of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamic Effects of Single and Multiple Ascending Doses of GDC-0334 and the Effect of Food on the Pharmacokinetics of GDC-0334 in Healthy Adult Participants

Healthy Volunteers

United Kingdom
Xenon Pharmaceuticals Inc.

Completed

Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Oral Doses of XEN901

Healthy Volunteers

United Kingdom
Concert Pharmaceuticals

Completed

Multiple Ascending Dose Study of CTP-692 in Healthy Volunteers

Healthy

United States
Wockhardt

Completed

Evaluate The Safety, Tolerability and Pharmacokinetics Of Multiple Ascending Oral Doses Of WCK 4873 In Healthy Adult Volunteers

Healthy
Astellas Pharma Global Development, Inc.

Completed

A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of MA-0211 in Healthy Adult Subjects Including a Food Effect Cohort

Healthy Volunteers

United States
Janssen Research & Development, LLC

Completed

A Single Ascending Dose Study in Healthy Participants and Multiple Dose Study of JNJ-55920839 in Participants With Mild to Moderate Systemic Lupus Erythematosus

Healthy | Systemic Lupus Erythematosus

United States, Spain, Romania, Taiwan, Belgium, Poland, Moldova, Republic of
Takeda

Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Ascending Single- and Multiple-Doses of TAK-020 in Healthy Volunteers

Healthy Volunteers

United States
Daiichi Sankyo, Inc.

Terminated

Effects of Multiple Doses of CS-8080 in Healthy Volunteers

Healthy

United States
AstraZeneca

Completed

Single + Multiple Ascending Dose and Food Effect Study of AZD7986 in Healthy Volunteers, PK, PD and Safety Study

Safety, Pharmacokinetics, Pharmacodynamics, Food Effect

United Kingdom
Vitae Pharmaceuticals Inc., an Allergan affiliate

Completed

An Ascending Multiple Dose Study With VTP-43742 in Healthy Volunteers and Psoriatic Patients

Psoriasis

United States
Vitae Pharmaceuticals Inc., an Allergan affiliate

Completed

An Ascending Multiple Dose Study With VTP-43742 in Healthy Volunteers

Psoriasis

United States
Pfizer

Completed

Clinical Trial In Healthy Volunteers And Health Elderly Volunteers To Evaluate The Safety, Tolerability And Blood Concentration After Single And Multiple Escalating Oral Doses Of PF-06751979.

Healthy Subjects

Belgium
Pfizer

Completed

A Study To Understand Safety And Plasma Concentrations Of PF-06669571 During And Following The Oral Administration Of Single And Multiple Doses Of PF-06669571 In Healthy Volunteers Under Fasted And Fed Conditions

Healthy

United States
Crinetics Pharmaceuticals Inc.

Completed

Single and Multiple-Ascending Dose Study of CRN00808 in Healthy Volunteers

Healthy Volunteers

Australia
Dongguan HEC TaiGen Biopharmaceuticals Co., Ltd.
R&G Pharma Studies Co.,Ltd.

Completed

To Evaluate the Safety, Tolerability, and Pharmacokinetics Profile in Healthy Chinese Volunteers of TG-2349

Healthy Chinese Volunteers

China
Dongguan HEC TaiGen Biopharmaceuticals Co., Ltd.
R&G Pharma Studies Co.,Ltd.

Completed

To Evaluate PK and Safety Profile of Oral MAD of Separately Using TG-2349, DAG181 or Combination in Healthy Chinese Volunteers

Healthy Chinese Volunteers

China
Ablynx

Completed

ALX-0171 Phase I Study, Evaluating Single Ascending Dose and Multiple Dose in Healthy Male Volunteers

RSV Infection

Netherlands
University of Washington
National Institute of General Medical Sciences (NIGMS)

Completed

The Effects of Multiple Dose Fluoxetine and Metabolites on CYP1A2, CYP2C19, CYP2D6 and CYP3A4 Activity (FLUOXETINE)

Healthy Volunteers | Drug-Drug Interaction
AstraZeneca
Parexel

Completed

Multiple-ascending Dose Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD9977 in Healthy Male Subjects

Healthy Volunteers

United Kingdom
Aelis Farma
National Institute on Drug Abuse (NIDA)

Completed

Multiple Ascending Dose to Study the Safety, Tolerability, PK and PD Effects of AEF0117

Healthy Volunteers

United States
Biota Pharmaceuticals, Inc.

Completed

Safety and Pharmacokinetics Study of Multiple Ascending Doses of BTA-C585 in Healthy Volunteers

Healthy Volunteers | Pharmacokinetics

United States
Enterome
Quotient Clinical

Completed

First-in-Human Single and Multiple Dose of EB8018

Healthy Volunteers

United Kingdom
ZZ Biotech, LLC

Completed

Safety and Pharmacokinetics of Single and Multiple Ascending Doses of 3K3A-APC in Healthy Adult Volunteers

Healthy

Austria
Cinclus Pharma AG

Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of X842 in Human: A Single/Multiple Ascending Dose Study

Healthy Volunteers

Sweden
Bristol-Myers Squibb

Terminated

Single Ascending Dose and Multiple Ascending Dose Study in Healthy Participants and Proof of Mechanism Study in Patients With Ulcerative Colitis

Healthy Volunteers | Ulcerative Colitis

Australia, Georgia, Moldova, Republic of

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