Search clinical trials for: omeprazole

Total 442 results

Agricultural University of Athens

Completed

Effects of Biofunctional Orange Juice on Cardiometabolic Risk Markers

Hypertension | Dyslipidemias | Overweight and Obesity | Prediabetes

Greece
Bristol-Myers Squibb

Completed

A Study to Assess the Effect of BMS-986419 on the Single Dose Drug Levels of Probe Substrates in Healthy Participants

Healthy Volunteers

United States
InventisBio Co., Ltd

Active, not recruiting

A Study to Evaluate the Effects of D-1553 on PK of Midazolam, Caffeine, Rosuvastatin, Furosemide, Digoxin, and Itraconazole or Omeprazole on PK of D-1553

Healthy Male

China
Bristol-Myers Squibb

Completed

A Study to Evaluate the Drug-drug Interaction Potential of BMS-986196 in Healthy Participants

Healthy Volunteers

United States
University of Southern California
National Cancer Institute (NCI); Brooklyn ImmunoTherapeutics, LLC

Active, not recruiting

IRX-2 Regimen in Treating Women With Cervical Squamous Intraepithelial Neoplasia 3 or Squamous Vulvar Intraepithelial Neoplasia 3

Cervical Squamous Cell Carcinoma In Situ | Vulvar High Grade Squamous Intraepithelial Lesion

United States
AnHeart Therapeutics Inc.

Completed

Study the Effect of Omeprazole on AB-106 Pharmacokinetics

Pharmacokinetic Study

China
Boehringer Ingelheim

Completed

A Study in Healthy People to Test Whether BI 730357 Influences the Amount of Caffeine, Warfarin, Omeprazole, and Midazolam in the Blood

Healthy

Germany
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Drug-drug Interaction Study Of Fluzoparib (SHR3162) on Patients With Recurrent Ovarian Cancer

Recurrent Ovarian Cancer

China
Alexion

Completed

A Study of ALXN1840 (Coated and Non-coated) Administered With And Without Omeprazole In Healthy Adults

Healthy

United States
Alexion

Completed

A Study of ALXN1840 (Non-coated) Administered With And Without Omeprazole In Healthy Adults

Healthy

United States
Merck KGaA, Darmstadt, Germany

Completed

Effect of a Proton Pump Inhibitor on the PK of Tepotinib

Healthy

Germany
Janssen Research & Development, LLC

Suspended

A Study to Evaluate the Effect of Ustekinumab on Cytochrome P450 Enzyme Activities Following Induction and Maintenance Dosing in Participants With Active Crohn's Disease or Ulcerative Colitis

Crohn Disease | Ulcerative Colitis

Germany, United States, United Kingdom, Belgium
Epizyme, Inc.

Completed

Open-Label, Multicenter, Two-Part, Phase 1 Study to Characterize Effects of a Moderate CYP3A Inhibitor on PK of Tazemetostat, Effects of Tazemetostat on PK of CYP2C8 and CYP2C19 Substrates, and Effect of Increased Gastric pH on PK of Tazemetostat in B-cell Lymphoma or Advanced Solid Tumor Patients

Mantle Cell Lymphoma | Marginal Zone Lymphoma | Advanced Solid Tumor | Diffuse Large B Cell Lymphoma | Primary Mediastinal Lymphoma

United States
Emory University

Terminated

PROUD Study - Preventing Opioid Use Disorders

Anesthesia | Opioid Use

United States
zr Pharma & GmbH

Completed

Pharmacokinetic Drug-Drug Interaction Study of Rucaparib (DDI)

Neoplasms

Poland
Pfizer
Pierre Fabre Laboratories

Active, not recruiting

Pharmacokinetic Drug-drug Interaction Study of Encorafenib and Binimetinib on Probe Drugs in Patients With BRAF V600-mutant Melanoma or Other Advanced Solid Tumors

Advanced Solid Tumors | Metastatic Melanoma

United States, Spain, Belgium, Canada, Netherlands
Jiangsu HengRui Medicine Co., Ltd.

Completed

Effect of Omeprazole on the Pharmacokinetics of SHR6390 in Healthy Subjects

Advanced Solid Tumor

China
Victoria Rollason

Active, not recruiting

PROGRESSive Withdrawal Esomeprazole and Acid-related Symptoms (PROGRESS)

Stomach Diseases

Switzerland
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Drug-drug Interaction Study of Famitinib Malate With a Proton Pump Inhibitor in Healthy Adult Subjects

Tumor

China
Iyad Naeem Muhammad, PhD

Completed

Eradication of H. Pylori Infection With Moxifloxacin (RCT)

Helicobacter Pylori Infection | Helicobacter Pylori Infection, Susceptibility to

Pakistan
PT Kalbe Farma Tbk
PT Pharma Metric Labs

Completed

Bioequivalence Study of 20 mg Omeprazole Capsules in Indonesia Healthy Subject

Drug Use

Indonesia
University of Karachi
Hunan Xinhui Pharmacy Limited Company

Completed

Efficacy and Safety of Houtou Jianweiling Tablet in the Treatment of Chronic Non-Atrophic Gastritis (CT)

Gastritis

Pakistan
Jazz Pharmaceuticals

Completed

Study to Evaluate the Effect of Rifampicin, Ketoconazole, and Omeprazole on the Pharmacokinetics of Sativex

Evaluation of Pharmacokinetics of Sativex in the Absence and Presence of a Known Inducer of CYP3A4 | Evaluation of Pharmacokinetics of Sativex in the Absence and Presence of a Potent Inhibitor of CYP3A4 | Evaluation of Pharmacokinetics of Sativex in the Absence and Presence of a CYP2C19...

United Kingdom
Hoffmann-La Roche

Completed

Bioavailability and Bioequivalence of Two Risdiplam Tablets in Healthy Participants

Muscular Atrophy, Spinal

United States
Northwestern University
National Institutes of Health (NIH); National Center for Complementary and...

Completed

Placebo In Chronic Back Pain - Double-Blind Randomized Control Trial

Chronic Low Back Pain

United States
University of Chicago

Withdrawn

The Effect of NSAIDs After a Rotator Cuff Repair Surgery.

Rotator Cuff Tear

United States
Jiangsu HengRui Medicine Co., Ltd.

Completed

The DDI Study Had Been Designed to Investigate the Effect of SHR3680 on the Pharmacokinetics of Midazolam, S-Warfarin and Omeprazole

Prostate Cancer Patients

China
Icahn School of Medicine at Mount Sinai

Completed

High Dose Dual Therapy vs Clarithromycin Triple Therapy for Treatment Naive H Pylori Infection in an Urban Population

Helicobacter Pylori Infection

United States
Poznan University of Medical Sciences

Active, not recruiting

Omeprazole and Famotidine in Chronic Dysfunction of the Transplanted Kidney

Kidney Rejection Transplant

Poland
Imperial College London

Terminated

Preventing Cardiac Complication of COVID-19 Disease With Early Acute Coronary Syndrome Therapy: A Randomised Controlled Trial. (C-19-ACS)

COVID-19

United Kingdom
Eli Lilly and Company
Loxo Oncology, Inc.

Completed

Study of H2 Antagonist and a Proton Pump Inhibitor of Selpercatinib in Healthy Participants

Healthy

United States
AstraZeneca

Completed

Study to Assess the Effect of Co-Administration of AZD9833 on the Pharmacokinetics of Midazolam, of Omeprazole, of Celecoxib and of Dabigatran Etexilate in Healthy Postmenopausal Female Volunteers

Healthy Volunteers

United States
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Pharmacokinetic Study to Evaluate the Drug Interaction Between HRS5091 and Probe Drugs in Healthy Volunteers

Chronic Hepatitis B

China
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Pharmacokinetic Study to Evaluate the Drug Interaction Between SHR0302 and CYP Substrates in Healthy Volunteers

Rheumatoid Arthritis

China
Eli Lilly and Company

Completed

A Study of Imlunestrant (LY3484356) in Female Healthy Participants

Healthy

United States
R-Pharm International, LLC
IQVIA RDS Ireland Ltd; Thermo Fisher Scientific FS

Completed

Study in Subjects With Rheumatoid Arthritis to Evaluate the Effect of a Single Dose of Olokizumab on the Pharmacokinetics of Substrates for CYP1A2, CYP2C9, CYP2C19 and CYP3A4

Rheumatoid Arthritis

Bulgaria, Moldova, Republic of
Aboca Spa Societa' Agricola
University of Roma La Sapienza; Doppel Farmaceutici; BMR Genomics

Completed

Efficacy and Safety Evaluation of Neobianacid® in GERD and EPS

GERD | EPS

Italy
Apkar Apkarian
National Institutes of Health (NIH); National Center for Complementary and...

Completed

Placebo In Chronic Back Pain (Phase 2) (PICP2)

Chronic Low Back Pain

United States
Amgen

Completed

A Study to Evaluate the Impact of Acid-reducing Agents on the Pharmacokinetics (PK) of AMG 510 in Healthy Participants

Healthy Participants

United States
MetroHealth Medical Center

Completed

Symptom Control Satisfaction With Proton Pump Inhibitor Regimen

Heartburn

United States
Amgen

Completed

Study to Evaluate the Drug-drug Interaction Effect of Omeprazole on the Pharmacokinetics (PK) of AMG 510 in Healthy Participants

Healthy Participants

United States
AstraZeneca
Parexel

Terminated

A Study to Assess the Effects of Itraconazole, Rifampicin, and Omeprazole on Pharmacokinetics of Adavosertib

Advanced Solid Tumours

United States, Spain
Jiangsu HengRui Medicine Co., Ltd.
The Third Xiangya Hospital of Central South University

Completed

Effect of Omeprazole on PK of Fluzoparib in Healthy Male Subjects

Advanced Solid Tumor

China
Merck Sharp & Dohme LLC

Completed

A Study of MK-8033 in Patients With Advanced Solid Tumors (MK-8033-001)

Advanced Cancer
Afferent Pharmaceuticals, Inc.
Celerion

Completed

A Multiple-Dose Pharmacokinetics Study of Two Gefapixant (AF-219/MK-7264) Formulations

Healthy

United States
Afferent Pharmaceuticals, Inc.
Celerion

Completed

A Study to Assess the Effect of Intragastric pH and Fasting on the Pharmacokinetics of Gefapixant (AF-219/MK-7264)

Healthy Volunteers
Eli Lilly and Company
Loxo Oncology, Inc.

Completed

A Study of Effect of Food and a Proton Pump Inhibitor on Selpercatinib (LY3527723) in Healthy Participants

Healthy

United States
Xspray Pharma AB
Axis Clinicals Limited

Completed

Evaluating the Effects of Omeprazole on the Pharmacokinetics of XS004 (Dasatinib) Tablets in Healthy Adult Subjects Under Fasting Conditions

Pharmacokinetics | Drug Interactions

United States
Kadmon Corporation, LLC
Quotient Sciences

Completed

Drug-drug Interaction Between Belumosudil, Itraconazole, Rifampicin, Rabeprazole, and Omeprazole in Healthy Volunteers

Autoimmune Diseases | Drug-drug Interaction | Fibrotic Disease

United Kingdom
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Investigate the Effect of Single and Repeated Oral Doses of ACT-539313 on What the Body Does to Flurbiprofen, Omeprazole, Midazolam in Healthy Subjects

Healthy

Germany

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