Search clinical trials for: small interfering RNAs

Total 11838 results

Sichuan Kelun Pharmaceutical Research Institute...

Recruiting

A Study of SKB264 in Combination With Pembrolizumab Versus Pembrolizumab in Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

Non-Small Cell Lung Cancer

China
AstraZeneca

Not yet recruiting

Volrustomig Priming Regimens Exploratory Phase II Platform Study (eVOLVE-01)

Non-small Cell Lung Cancer
KaliVir Immunotherapeutics

Not yet recruiting

A Study of VET3-TGI in Patients With Solid Tumors (STEALTH-001)

Kidney Cancer | Renal Cell Carcinoma | Cervical Cancer | Mesothelioma | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Solid Tumor, Adult | Microsatellite Stable Colorectal Cancer | Melanoma Stage IV | Merkel Cell Carcinoma of Skin
First Affiliated Hospital of Zhejiang University

Recruiting

Efficacy and Safety of Modified Si Jun Zi Tang in Perioperative NSCLC Treatment (MSJZT-NSCLC)

Non Small Cell Lung Cancer | Perioperative Complication

China
Shanghai Chest Hospital

Recruiting

A Study of Molecular Residual, Dynamic Monitoring and Recurrence of Stage III Driver Mutated NSCLC

Non Small Cell Lung Cancer

China
Taizhou Hospital

Not yet recruiting

Toripalimab Plus Anlotinib for the Maintenance of Extensive Stage Small Cell (SCLC)

SCLC | Maintenance Treatment
University Hospital, Brest

Not yet recruiting

Impact of Respiratory Rehabilitation on Quality of Life in Patients With Metastatic Non-small Cell Lung Cancer Treated With Immunotherapy and Chemotherapy in the Maintenance Phase (REHABIM)

Cancer
University of Palermo

Not yet recruiting

SGLT-2 Inhibitor and High-Dose Furosemide Plus Small-Volume Hypertonic Saline Solution in Acute HF (DAPA-TONIC)

Heart Failure With Reduced Ejection Fraction | Heart Failure With Preserved Ejection Fraction | Diabetes Type 2 | Heart Failure Acute
Hunan Province Tumor Hospital
Hunan Cancer Hospital

Recruiting

Efficacy and Resistance Mechanisms of IP in NSCLC With Leptomeningeal Metastases (EPIC)

Non-Small Cell Lung Cancer

China
Nerissa T. Viola

Not yet recruiting

First-in-human Study of Interferon-y PET Imaging to Assess Response to Immunotherapy

Non Small Cell Lung Cancer

United States
University of British Columbia
Canadian Institutes of Health Research (CIHR); McMaster University; Memorial... and other collaborators

Recruiting

Small Steps for Big Changes - Healthy Cities Implementation Science (HCIS)

PreDiabetes

Canada
Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Not yet recruiting

Dose Escalation Study of ZG006 in Participants With Advanced Small Cell Lung Cancer or Neuroendocrine Carcinoma, Followed by Dose Expansion Study in Participants With Neuroendocrine Carcinoma.

Neuroendocrine Carcinoma

China
Mayo Clinic

Recruiting

Fasting Mimicking Diet for Reducing Immune Related Adverse Events for Cancer Patients on Immune Checkpoint Inhibitors, FMD-ICI Trial

Malignant Solid Neoplasm | Melanoma | Renal Cell Carcinoma | Lung Non-Small Cell Carcinoma | Urothelial Carcinoma | Lung Small Cell Carcinoma

United States
Karl Landsteiner Institute for Lung Research and...
Klinik Pirawarth; Therme Wien Med

Not yet recruiting

Outpatient Pulmonary Rehabilitation in Non-small-cell Lung Cancer Receiving Immunotherapy (OPAL)

NSCLC Stage IV
Henan Cancer Hospital

Recruiting

An Exploratory Study of Efficacy and Safety of Iruplinalkib Tablets in Patients With ROS1 Positive Non-small Cell Lung Cancer

Non-Small Cell Lung Cancer

China
Shenzhen TargetRx, Inc.
The First Affiliated Hospital of Soochow University

Not yet recruiting

TGRX-326 Pharmacokinetic Mass Balance

Non Small Cell Lung Cancer
Sichuan Baili Pharmaceutical Co., Ltd.
Baili-Bio (Chengdu) Pharmaceutical Co., Ltd.

Not yet recruiting

A Study of BL-B01D1+PD-1 Monoclonal Antibody in Patients With Extensive-stage Small Cell Lung Cancer

Extensive-stage Small-cell Lung Cancer

China
Shanghai Chest Hospital

Not yet recruiting

Neoadjuvant Therapy of SBRT Sequencial With Toripalimab and Chemotherapy in Resectable Stage II-III NSCLC Patients(neoR-TORCH) (neoR-TORCH)

Stage II-III Non-small Cell Lung Cancer
Sir Run Run Shaw Hospital

Not yet recruiting

A Study of SBRT Combined With Puterizumab in Intrapulmonary Metastasis From NSCLC

Non-Small-Cell Lung Cancer
Suzhou Suncadia Biopharmaceuticals Co., Ltd.

Not yet recruiting

Clinical Study of SHR-A1921 Combined With Adebrelimab and SHR-8068 With or Without Carboplatin in the Treatment of Advanced NSCLC

Advanced Non-small Cell Lung Cancer
Daping Hospital and the Research Institute of Surgery...

Not yet recruiting

Osimertinib and Etoposide as First-Line Treatment in Osimertinib-Resistant Advanced EGFR-Mutant NSCLC

Non Small Cell Lung Cancer | Non Small Cell Lung Cancer Stage IIIB | EGFR Gene Mutation | Non-small Cell Lung Cancer Stage IV
Novartis Pharmaceuticals

Not yet recruiting

A Study to Investigate LDL-cholesterol Lowering With Inclisiran Compared to Bempedoic Acid in Patients With Atherosclerotic Cardiovascular Disease.

Hypercholesterolemia
Zhejiang Provincial People's Hospital

Recruiting

Fundus Optical coheRence Tomography Angiography Evaluation for Small-vessel Health in Cerebral Small Vessel Disease (FRESH-CSVD)

Cerebral Small Vessel Diseases | Retinal Ischemia | Choroid; Injury

China
Fundación GECP

Not yet recruiting

Study of Treatment With Sacituzumab and Zimberelimab for Patients With Lung Cancer Confined to the Chest and Previously Operated on Who Were Not Disease-free. (ARIAN)

Lung Diseases | Carcinoma, Non-Small-Cell Lung | Resectable Lung Non-Small Cell Carcinoma

Spain
Amgen

Not yet recruiting

Pharmacokinetic Similarity Between ABP 234 and Keytruda® (Pembrolizumab) (Eucalyptus)

Early-stage Non-squamous Non-small Cell Lung Cancer (NSCLC)
Nanfang Hospital, Southern Medical University

Not yet recruiting

PD-L1 Inhibitor Combined With Apatinib as First-line Maintenance Treatment for Extensive-stage Small Cell Lung Cancer

Small Cell Lung Cancer Extensive Stage
Jiangsu HengRui Medicine Co., Ltd.

Not yet recruiting

A Study of SHR-A1811 in First-line Treatment of Patients With Advanced or Metastatic Non-small Cell Lung Cancer With HER2 Mutations

Non-Small Cell Lung Cancer With HER2- Mutations

China
Beijing Geekgene Technology Co., LTD

Recruiting

a Single-arm, Single-center, Open Clinical Study (GK-01)

Cervical Cancer | Gastric Cancer | Esophageal Cancer | Non-Small Cell Lung Cancer NSCLC | Triple Negative Breast Cancer TNBC

China
Necmettin Erbakan University
Health Institutes of Türkiye (TUSEB)

Not yet recruiting

The Impact of Probiotic on Survival and Treatment Response in Metastatic Non-small Cell Lung Cancer Patients

Metastatic Non-small Cell Lung Cancer

Turkey
BeiGene

Not yet recruiting

A Phase 1 Study of BGB-B2033, Alone or in Combination With Tislelizumab, in Participants With Advanced or Metastatic Solid Tumors

Metastatic Solid Tumor | Advanced Hepatocellular Carcinoma | Metastatic Hepatocellular Carcinoma | Alpha-fetoprotein (AFP)-Producing Gastric Cancer | Extragonadal Yolk Sac Tumors | Glypican-3 (GPC3)-Positive Squamous Non-small Cell Lung Cancer
Sun Yat-sen University

Not yet recruiting

ctDNA-MRD Guided Consolidation Toripalimab in Stage IB-IIIA NSCLC (CONTINUE)

Lung Cancer, Nonsmall Cell
Roswell Park Cancer Institute

Not yet recruiting

An Investigational Scan (124I-hJAA-F11 PET/CT) for Diagnosing Lung Cancer

Stage IV Lung Cancer | Lung Non-Small Cell Carcinoma | Extensive-stage Small-cell Lung Cancer | Limited-stage Small-cell Lung Cancer | Stage IIIA Lung Cancer
Zeng Jian

Recruiting

A Study Comparing Neoadjuvant Chemoimmunotherapy and Immuno-consolidationafter Compared With Immunoconsolidation After Radical Chemoradiotherapy for Stage III Potentially Resectable NSCLC

Non Small Cell Lung Cancer

China
Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co...

Not yet recruiting

A Study of FZ-AD005 in Patients With Advanced Solid Tumors

Advanced Solid Tumor, SCLC(Small Cell Lung Cancer) or LCNEC (Large Cell Neuroendocrine Carcinoma)

China
Medical University of South Carolina

Not yet recruiting

Study of Fingolimod

Non Small Cell Lung Cancer | Small-cell Lung Cancer
Beijing Cancer Prevention & Treatment Society
Cancer Institute and Hospital, Chinese Academy of Medical Sciences

Recruiting

A Prospective, Multicenter, Non-interventional, Real-world Study to Characterize Changes in Molecular Markers After Three Weeks of Targeted Therapy With Oxitinib in EGFRm NSCLC (pre-FLAME)

Non Small Cell Lung Cancer

China
National University Hospital, Singapore

Not yet recruiting

A Value-Driven Study on Reducing Immune Checkpoint Inhibitor Dosing Frequency in Advanced Cancers (VALUE-CHECK)

Carcinoma, Hepatocellular | Gastric Adenocarcinoma | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Oesophageal Cancer | GastroEsophageal Cancer

Singapore
Merck Sharp & Dohme LLC

Not yet recruiting

Pembrolizumab With or Without Maintenance Sacituzumab Tirumotecan (Sac-TMT; MK-2870) in Metastatic Squamous Non-small Cell Lung Cancer (NSCLC) [MK-2870-023]

NSCLC | Non-small Cell Lung Cancer
Leiden University Medical Center
The Dutch Brain Foundation (funding)

Not yet recruiting

Stimulating Amyloid Clearance in Cerebral Amyloid Angiopathy (Clear-Brain)

Cerebral Amyloid Angiopathy
Jinghui Wang

Recruiting

A Prospective, Single-arm, Phase II Clinical Trial to Evaluate the Efficacy and Safety of Tafolecimab and Sintilimab Combined With Chemotherapy in Patients With Advanced or Metastatic Driver Gene-negative Non-small Cell Lung Cancer After Failure of First-line Immunotherapy.

Lung Cancer

China
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Not yet recruiting

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics (COSMIC)

Melanoma | Non-Hodgkin Lymphoma | Breast Carcinoma | Lung Non-Small Cell Carcinoma | Colorectal Carcinoma
University of Cologne
AstraZeneca

Not yet recruiting

Maintenance Durvalumab (MEDI4736) and Olaparib (AZD2281) After Standard 1st Line Treatment (Carboplatin/Cisplatin, Etoposide, Durvalumab) in HRD Positive Extensive Disease (ED) Small-cell Lung Cancer (SCLC) (GUIDANCE)

Small Cell Lung Carcinoma
National Cancer Centre, Singapore

Recruiting

A Pan-Asian Clinical Database of EGFR Exon 20 Insertion Mutated NSCLC

Advanced EGFR Exon 20 Insertion Mutated Non-Small Cell Lung Cancer

Korea, Republic of, Taiwan, Singapore
University of Edinburgh

Not yet recruiting

Retinal Vessel Leakage in Cerebral Small Vessel Disease

Cerebral Small Vessel Diseases | Vascular Dementia | Lacunar Stroke
Hansoh BioMedical R&D Company

Not yet recruiting

A Study of HS-20117 Combined With Aumolertinib in Participants With Advanced Non-Squamous Non-Small Cell Lung Cancer

Non-Squamous Non-Small Cell Lung Cancer
Jacobio Pharmaceuticals Co., Ltd.

Not yet recruiting

JAB-21822 Combined With JAB-3312 Compared SOC in the First Line for Treatment of Advanced Non-small Cell Lung Cancer With KRAS p.G12C Mutation

Advanced Non-squamous Non-small-cell Lung Cancer | Metastatic Non-squamous Non Small Cell Lung Cancer
Yantai LNC Biotechnology Singapore PTE. LTD.

Not yet recruiting

Clinical Study of 18F-Alfatide Injection PET/CT

Non-Small Cell Lung Cancer NSCLC

China
AstraZeneca
Daiichi Sankyo

Not yet recruiting

A Study to Investigate the Efficacy and Safety of Dato-DXd With or Without Osimertinib Compared With Platinum Based Doublet Chemotherapy in Participants With EGFR-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (TROPION-Lung15)

Metastatic Non-small Cell Lung Cancer
Sunshine Guojian Pharmaceutical (Shanghai) Co.,...

Not yet recruiting

A Phase II Study of SSGJ-707 Combination Therapy in Advanced NSCLC Patients

First-line Advanced NSCLC Patients

China
Ospedale San Raffaele
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico

Recruiting

Identification of New Biological Markers for the Progression of Mycobacterium Abscessus-induced Lung Disease in Cystic Fibrosis (BioMol-MA)

Non-Tuberculous Mycobacterial Pneumonia | Cystic Fibrosis Lung

Italy

Search clinical trials for: small interfering RNAs

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