Search clinical trials for: Muscarinic

Total 1283 results

US Department of Veterans Affairs

Completed

Anticholinergic Therapy for Overactive Bladder in Parkinson's Disease

Overactive Bladder | Parkinson's Disease

United States
Astellas Pharma Inc
Astellas Pharma Europe B.V.

Completed

A Study of Solifenacin With Bladder Training Versus Solifenacin Alone in Patients With Overactive Bladder (SOLAR) (SOLAR)

Overactive Bladder | Urinary Incontinence | Urge Incontinence

France, Belgium, Spain, Turkey, Australia, Russian Federation, Hungary, Italy, Netherlands, Poland, Czech Republic
Astellas Pharma Inc

Completed

Efficacy & Safety Study of VESIcare® (Solifenacin Succinate) in Patients Wishing to Switch From Detrol LA® for Treatment of Overactive Bladder (VERSUS)

Urinary Bladder, Overactive

United States
Astellas Pharma Inc

Completed

A Study to Evaluate Solifenacin Succinate in Combination With Tamsulosin for the Treatment of Residual Overactive Bladder Symptoms (OAB) in Men. (VICTOR)

Urinary Incontinence

United States
Astellas Pharma Inc

Completed

Solifenacin Succinate Versus Tolterodine 4mg Once Daily (STAR)

Urinary Bladder, Overactive

France, United Kingdom, Spain, Belarus, Belgium, Ukraine, Denmark, Greece, Russian Federation, Czech Republic, Netherlands, Germany, Hungary, Italy, Slovakia, Sweden, Norway
Astellas Pharma Inc

Completed

A Multicenter VESIcare® Efficacy and Safety Study for the Treatment of Urgency Associated With Overactive Bladder (OAB) (VENUS)

Urinary Bladder, Overactive

United States
Astellas Pharma Inc

Completed

Solifenacin Succinate 5mg or 10mg Once Daily in the Treatment of Urgency Symptoms (SUNRISE)

Urinary Bladder, Overactive

France, United Kingdom, Belgium, Germany, Spain, Portugal, Greece, Russian Federation, Czech Republic, Poland, Hungary, Italy, Slovakia, Egypt
Astellas Pharma Inc

Completed

Open-label Study of the Efficacy and Safety of VESIcare® in Patients With Overactive Bladder Symptoms (VOLT)

Urinary Bladder, Overactive

United States
Pfizer

Completed

Post Marketing Surveillance Of Fesoterodine In Filipino Patients With Over Active Bladder

Over Active Bladder

Philippines
Astellas Pharma Inc

Completed

Post Marketing Survey of Vesicare in Japan (SET-Q)

Overactive Bladder

Japan
Boehringer Ingelheim

Completed

Efficacy and Tolerability of Buscopan Plus in Painful Gastric or Intestinal Spasms

Gastrointestinal Diseases
Astellas Pharma Europe B.V.

Completed

Study to Evaluate the Effect of Solifenacin and Mirabegron on the Tamsulosin Hydrochloride (HCl) Concentrations in Blood in Healthy Male Subjects

Healthy Subjects | Pharmacokinetics | Drug-Drug Interaction (DDI)

Germany
University of North Carolina, Chapel Hill
National Institute of Dental and Craniofacial Research (NIDCR)

Completed

Study of Anesthesia Techniques to Reduce Nausea and Vomiting After Jaw Corrective Surgery

Post-operative Nausea | Post-operative Vomiting | Nausea Persistent

United States
Astellas Pharma Inc

Completed

A Study With Combination Treatment (Tamsulosin Hydrochloride and Solifenacin Succinate) in Male Patients With LUTS/BPH (SATURN)

Lower Urinary Tract Symptoms | Prostatic Hyperplasia

France, Poland, Germany, Spain, Finland, Netherlands, Russian Federation, Czech Republic, Hungary, Norway, Denmark, Slovakia, Sweden, Austria, Portugal, United Kingdom
Novartis Pharmaceuticals

Completed

Efficacy, Safety and Tolerability of NVA237 in Patients With Chronic Obstructive Pulmonary Disease (GLOW7)

Chronic Obstructive Pulmonary Disease (COPD)

China, Philippines, Korea, Republic of, India
Forest Laboratories

Completed

Safety and Efficacy of Vilazodone in Major Depressive Disorder (VLZ-MD-01)

Major Depressive Disorder

United States
Astellas Pharma Inc

Completed

Solifenacin Succinate With Tamsulosin HCl in Males With Lower Urinary Tract Symptoms and Bladder Outlet Obstruction

Lower Urinary Tract Symptoms | Bladder Outlet Obstruction

United States, Czech Republic, Poland, Hungary, Belgium, Germany
Astellas Pharma Europe B.V.

Completed

Study to Evaluate the Effect of Solifenacin and Mirabegron on the Digoxin Concentrations in Blood in Healthy Subjects

Healthy Subjects | Pharmacokinetics | Drug-Drug Interaction (DDI)

Germany
Mahidol University

Completed

0.6 vs. 1.2 mg Atropine Together With Neostigmine 2.5 mg on Heart Rate in Patient Receiving Muscle Relaxant

Bradycardia | Neostigmine Adverse Reaction | Adverse Reaction to Belladonna or Atropine
Astellas Pharma Inc
Astellas Pharma Korea, Inc.

Completed

A Study to Evaluate Response of Over Active Bladder Symptom Score to Solifenacin Treatment (RESORT-2)

Over Active Bladder

Korea, Republic of
University Hospital, Brest
Ministry of Health, France

Completed

Treatment of Hyperhidrosis With Oxybutynin (H²O)

Hyperhidrosis

France
Antares Pharma Inc.

Completed

Study of Topically Administered Oxybutynin Gel in Patients With Urge Incontinence

Urinary Frequency | Urge Urinary Incontinence

United States
Pontificia Universidad Catolica de Chile

Unknown

A New More Efficient Cycloplegia Scheme

Refractive Errors

Chile
Buddhist Tzu Chi General Hospital

Completed

Antimuscarinics as the First-line Treatment for Male With IPSS-V/S≤1

Bladder Outlet Obstruction

Taiwan
Boehringer Ingelheim

Completed

Safety and Pharmacokinetics of Quinidine Alone and in Combination With Dabigatran Etexilate

Healthy
Boehringer Ingelheim

Terminated

Relative Bioavailability of Dabigatran Etexilate Capsules With and Without Quinidine Sulfate Tablets and to Measure the Effect of Quinidine on the Absorption of Fexofenadine in Healthy Male and Female Volunteers

Healthy
Seoul National University Hospital
Seoul National University Bundang Hospital

Completed

Clinical Trial to Investigate the Effect on Corrected QT Interval Prolongation by Psychotropic Drugs

Healthy

Korea, Republic of
Astellas Pharma Europe B.V.

Completed

A Study to Evaluate Whether Verapamil Has an Effect on the Uptake and Elimination of Solifenacin and Tamsulosin When Administered in a Combination Tablet

Healthy Subjects | Drug-Drug Interaction (DDI)

France
Magna Pharmaceuticals, Inc.

Unknown

StahistRx Phase 2, Five-arm, Parallel Group, Active vs Active, Double-blind Study

Rhinitis, Seasonal, Allergic

United States
Asan Medical Center
Samsung Medical Center; Seoul National University Hospital; Cheil General Hospital... and other collaborators

Completed

Observational Study to Estimate the Dry Mouth in OAB Patients With Solifenacin (OAB)

Overactive Bladder

Korea, Republic of
Astellas Pharma Europe B.V.

Completed

A Study to Compare the Amount of Drug in the Blood After a Single Tablet EC905 Containing Solifenacin and Tamsulosin is Taken by Healthy Males Compared to Separate Tablets of Solifenacin and Tamsulosin

Healthy Subjects | Pharmacokinetics | EC905

United Kingdom
Astellas Pharma Europe B.V.

Completed

A Study to Evaluate How Tamsulosin (at 1 Dose) and Solifenacin (at 2 Different Doses) Are Taken up From the Intestine, Distributed Through the Body and Eliminated From the Body When Administered in Combination as a Single Tablet (Called EC905)

Healthy Subjects | Pharmacokinetics | EC905 | Multiple Dose

United Kingdom
Bay State Clinical Trials, Inc.

Terminated

Use of Percutaneous Tibial Nerve Stimulation With Solifenacin or Placebo to Treat Refractory Overactive Bladder

Overactive Bladder

United States
University of Southern California
Crowley Carter Foundation; Don and Linda Carter Foundation; United Cerebral Palsy...

Completed

Childhood Hypertonia of Central Origin: A Trial of Anticholinergic Treatment Effects

Dystonia

United States
American Academy of Otolaryngology-Head and Neck...
Duke University

Completed

Study of the Effectiveness of Cevimeline on Oral Health in Patients With Radiation Induced Xerostomia (SMILE)

Xerostomia

United States
Novartis Pharmaceuticals

Completed

The Effect of QVA149 on Health Related Quality of Life in Patients With Chronic Obstructive Pulmonary Disease (COPD) (QUANTIFY)

Chronic Obstructive Pulmonary Disease (COPD)

Germany
US Department of Veterans Affairs

Completed

Behavioral Treatment of Overactive Bladder in Men (MOTIVE)

Overactive Bladder

United States
Drexel University
Merck Sharp & Dohme LLC

Completed

Comparison of Aprepitant Versus Aprepitant and Transdermal Scopolamine for Preventing Postoperative Nausea and Vomiting

Nausea | Vomiting

United States
Stanford University
National Institute of Mental Health (NIMH)

Completed

Combining Antidepressant Medication and Psychotherapy for Insomnia to Improve Depression Outcome

Insomnia | Major Depressive Disorder

United States
University of California, San Francisco
Baxter Healthcare Corporation

Completed

Impact of Anesthetic Choice (Sevoflurane Versus Desflurane) on Airway Reflex Recovery in the Context of Antagonized Neuromuscular Block

Airway Reflexes, Protective | Recovery After Neuromuscular Block | Anesthetic Recovery

United States
Drexel University College of Medicine
Merck Sharp & Dohme LLC

Completed

Comparison of Oral Aprepitant and Transdermal Scopolamine for Preventing Postoperative Nausea and Vomiting

Nausea | Vomiting

United States
Novartis Pharmaceuticals

Completed

Efficacy, Safety, and Tolerability of NVA237 Compared to Tiotropium in Patients With Chronic Obstructive Pulmonary Disease (COPD) (GLOW5)

Chronic Obstructive Pulmonary Disease

Germany, India, South Africa, Croatia, Estonia, Poland, Lithuania, Guatemala, Czech Republic, France, Philippines, Korea, Republic of, Taiwan, Canada, Latvia
National Institute of Mental Health (NIMH)

Completed

Combining Medications to Enhance Depression Outcomes (CO-MED)

Major Depressive Disorder

United States
Craig J. Huang

Completed

Effectiveness of Atropine and Glycopyrrolate to Reduce Hyper Salivation With Ketamine Sedation

Sialorrhea

United States
Ewha Womans University
GlaxoSmithKline

Completed

Neuroimaging Study of Bupropion Treatment in Patients With Major Depressive Disorder

Major Depressive Disorder

Korea, Republic of
BL&H Co., Ltd

Completed

A Comparative Bronchial Provocation Study With Mannitol and Methacolinie in a Korean Population

Asthma
Sisli Hamidiye Etfal Training and Research Hospital

Completed

Safety Study of Hyoscine N Butyl Bromide in Active Management of Labor (HBB)

Labor Fast

Turkey
Pfizer

Completed

A 12 Week Study to Confirm the Effectiveness of 8mg of Fesoterodine Compared to 4mg of Fesoterodine

Overactive Bladder

Korea, Republic of, United States, Denmark, Germany, Canada, Hungary, Poland, France, United Kingdom, Slovakia, Sweden, Mexico, Czech Republic, Finland, Italy, Lithuania, Argentina, Chile, Colombia, Egypt, Greece, Norway, Philippines, Russian Federation and more
Dr Cipto Mangunkusumo General Hospital
Astellas Pharma Indonesia Inc.; Pharos Life Corporation

Unknown

The Efficacy of Solifenacin Succinate as Adjuvant Therapy for Urinary Tract Infection in Females

Urinary Tract Infection

Indonesia
Peking Union Medical College Hospital
Astellas Pharma China, Inc.; Beijing CAT Science Co., Ltd.

Completed

Effectiveness and Safety Study of Solifenacin Succinate and Solifenacin Succinate + Estrogen to Treat OAB in Postmenopausal Women (OAB)

Overactive Bladder | Urination Disorders | Postmenopausal Disorder

China

Search clinical trials for: Muscarinic

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