Clinical Trials Sponsored by SPECNOVA LLC

Total 10769 results

Indiana University
University of California, Los Angeles; Yale University; University of Maryland; University of Kansas Medical Center and other collaborators

Completed

A Double-Blind Trial of Adjunctive Valacyclovir to Improve Cognition in Early Phase Schizophrenia (VISTA)

Schizophrenia

United States
Foundation for the National Institutes of Health
M.D. Anderson Cancer Center; Eli Lilly and Company; National Institute of Diabetes... and other collaborators

Unknown

A Prospective Observational Study to Evaluate Acute Kidney Injury Biomarkers In Patients Receiving First Cycle of Cisplatin Chemotherapy for Head and Neck Cancers

Head and Neck Cancer

United States
Columbia University
National Institute on Drug Abuse (NIDA); Medical University of South Carolina; University of Pittsburgh and other collaborators

Completed

HIV Rapid Testing & Counseling in Sexually Transmitted Disease (STD) Clinics in the U.S. (Aware)

HIV/AIDS | Sexually Transmitted Infections

United States
Utrecht Institute for Pharmaceutical Sciences
Uppsala University; Erasmus Medical Center; Newcastle University; University of... and other collaborators

Completed

EUropean Pharmacogenetics of AntiCoagulant Therapy - Phenprocoumon (EU-PACT)

Venous Thromboembolism (VTE) | Atrial Fibrillation (AF)

Germany, Austria, Netherlands
Institut National de la Santé Et de la Recherche...
Charite University, Berlin, Germany; Cliniques universitaires Saint-Luc- Université... and other collaborators

Completed

Effect of Risedronate on Bone Morbidity in Fibrous Dysplasia of Bone (PROFIDYS)

Fibrous Dysplasia of Bone

Belgium, France, Germany, Netherlands
Utrecht Institute for Pharmaceutical Sciences
Uppsala University; Erasmus Medical Center; Newcastle University; University of... and other collaborators

Completed

EUropean Pharmacogenetics of AntiCoagulant Therapy - Warfarin (EU-PACT)

Atrial Fibrillation | Venous Thromboembolism

Sweden, United Kingdom
Utrecht Institute for Pharmaceutical Sciences
Uppsala University; Erasmus Medical Center; Newcastle University; University of... and other collaborators

Completed

EUropean Pharmacogenetics of AntiCoagulant Therapy - Acenocoumarol (EU-PACT)

Atrial Fibrillation | Venous Thromboembolism

Netherlands, Greece
University of British Columbia
Eli Lilly and Company; Merck Sharp & Dohme LLC; Pfizer; Canadian Institutes of... and other collaborators

Recruiting

National Active Surveillance Network and Pharmacogenomics of Adverse Drug Reactions in Children

Adverse Drug Reaction (ADR)

Canada
Hospital San Carlos, Madrid
Merck Sharp & Dohme LLC; Hospital Universitario Ramon y Cajal; Complejo Hospitalario... and other collaborators

Completed

Golimumab Trough Levels in Patients With Ulcerative Colitis (GLMLEVEL)

Ulcerative Colitis

Spain
Merck KGaA, Darmstadt, Germany
Merck Serono GmbH, Germany; Merck B.V., Netherlands; Merck A.E., Greece; Merck... and other collaborators

Completed

PERgoveriS In Stratified Treatment for Assisted Reproductive Technique (PERSIST)

Assisted Reproductive Techniques | Reproductive Technology, Assisted

Italy, Russian Federation, United Kingdom, Germany, Poland, Finland, Slovakia, Netherlands, Denmark, France, Greece
Massachusetts Eye and Ear Infirmary
London School of Hygiene and Tropical Medicine; University of Pennsylvania; The... and other collaborators

Active, not recruiting

FLuorometholone as Adjunctive MEdical Therapy for TT Surgery (FLAME) Trial (FLAME)

Eye Diseases | Eyelid Diseases | Trichiasis | Trachomatous Trichiasis (TT) | Trachomatous

Ethiopia
Université de Sherbrooke
Fonds de la Recherche en Santé du Québec; Agence de la Sante et des Services... and other collaborators

Completed

Vulnerable Patients in Primary Care: Nurse Case Management and Self-management Support (V1SAGES)

Chronic Diseases

Canada
National Institute of Diabetes and Digestive and...
Boston University; Washington University School of Medicine; University of Alabama... and other collaborators

Completed

Aggrenox Prevention of Access Stenosis (GRAFT)

Kidney Failure

United States
Foundation for the National Institutes of Health
M.D. Anderson Cancer Center; Eli Lilly and Company; National Institute of Diabetes... and other collaborators

Unknown

Prospective Observational Study to Evaluate Biomarkers of Aminoglycoside Nephrotoxicity in Patients With Cystic Fibrosis

Cystic Fibrosis

United States
University of Ulster
Charite University, Berlin, Germany; University Hospital Southampton NHS Foundation... and other collaborators

Completed

Contribution of Cow's Milk to Iodine and Selenium Status in Women of Child-bearing Age (SIMI)

Selenium and Iodine Status

United Kingdom
Universitätsklinikum Hamburg-Eppendorf
Bristol-Myers Squibb; Eli Lilly and Company; UCB Pharma; Merck Sharp & Dohme LLC; AbbVi... and other collaborators

Recruiting

PsoBest - The German Psoriasis Registry

Psoriasis | Psoriatic-arthritis

Germany
Memorial Sloan Kettering Cancer Center
Johns Hopkins University; M.D. Anderson Cancer Center; Merck Sharp & Dohme LLC; Dana-Farber Cancer Institute and other collaborators

Completed

Clinical Study of Vorinostat in Combination With Etoposide in Pediatric Patients < 21 Years at Diagnosis With Refractory Solid Tumors

Solid Tumors | Relapsed/Refractory Sarcomas

United States, Canada
National Institute of Diabetes and Digestive and...
Boston University; Washington University School of Medicine; University of Alabama... and other collaborators

Completed

Clopidogrel Prevention of Early Arteriovenous (AV) Fistula Thrombosis (FISTULA)

Kidney Failure | Hemodialysis Fistula Thrombosis

United States
Finnish Institute for Health and Welfare
Finnish Institute of Occupational Health; Finnish Work Environment Fund; Berner... and other collaborators

Completed

STOPFLU: Is it Possible to Reduce the Number of Days Off in Office Work by Improved Hand-hygiene?

Gastroenteritis | Respiratory Infection

Finland
Baylor College of Medicine
M.D. Anderson Cancer Center; Massachusetts General Hospital; National Heart,... and other collaborators

Completed

Most Closely HLA Matched Allogeneic Virus Specific Cytotoxic T-Lymphocytes (CTL) (CHALLAH)

EBV Infection | Adenovirus Infection

United States
Haukeland University Hospital
The Research Council of Norway; The Royal Norwegian Ministry of Health; Norwegian... and other collaborators

Completed

WENBIT - Western Norway B Vitamin Intervention Trial (WENBIT)

Myocardial Infarction | Coronary Artery Disease | Cerebrovascular Stroke

Norway
U.S. Army Medical Research and Development Command
Walter Reed Army Institute of Research (WRAIR); Mahidol University; The Emmes... and other collaborators

Completed

HIV Vaccine Trial in Thai Adults

HIV Infection

Thailand
Ludwig Institute for Cancer Research
Memorial Sloan Kettering Cancer Center; National Taiwan University Hospital; Duke... and other collaborators

Terminated

Study of ADI-PEG 20 in Patients With Relapsed Sensitive or Refractory Small Cell Lung Cancer

Small Cell Lung Cancer

United States, Taiwan, Germany, Belgium, United Kingdom
University Hospital Inselspital, Berne
UMC Utrecht; Cliniques universitaires Saint-Luc- Université Catholique de Louvain and other collaborators

Completed

OPtimising thERapy to Prevent Avoidable Hospital Admissions in the Multimorbid Older People (OPERAM)

3 or More Chronic Conditions for 6 Months or Longer | 5 or More Regular Drugs

Belgium, Ireland, Netherlands, Switzerland
University Hospital Inselspital, Berne
UMC Utrecht; Cliniques universitaires Saint-Luc- Université Catholique de Louvain and other collaborators

Completed

Health Economic Evaluation Alongside the OPERAM Trial

3 or More Chronic Conditions for 6 Months or Longer | 5 or More Regular Drugs

Belgium, Ireland, Netherlands, Switzerland
Universitaire Ziekenhuizen KU Leuven
Universitair Ziekenhuis Brussel; Ziekenhuis Oost-Limburg; Centre Hospitalier... and other collaborators

Unknown

OCT Guided Magmaris RMS in STEMI (BESTMAG)

STEMI

Belgium
Central Hospital, Nancy, France
Sanofi; GlaxoSmithKline; Zambon SpA; Laboratoires URGO; Pierre Fabre Medicament; Bi... and other collaborators

Unknown

Allergy to Neuromuscular Blocking Agents and Pholcodine Exposure (ALPHO)

Neuromuscular Blocking Agents Anaphylaxis

France
Medicines for Malaria Venture
Washington University School of Medicine; Sanaria Inc.; Institute of Tropical... and other collaborators

Completed

Safety, Tolerability and Chemoprotective Activity of P218 in PfSPZ Challenge Model

Malaria

Belgium
Universitaire Ziekenhuizen KU Leuven
University Hospital, Ghent; Universitair Ziekenhuis Brussel; University Hospital... and other collaborators

Completed

Closed-loop Insulin Delivery in Pregnant Women With Type 1 Diabetes (CRISTAL)

Type1 Diabetes

Belgium, Netherlands
University of Liege
University Hospital, Gasthuisberg; University Hospital, Ghent; University Hospital... and other collaborators

Active, not recruiting

Minitransplants With HLA-matched Donors : Comparison Between 2 GVHD Prophylaxis Regimens

Hematological Malignancies | Graft-Versus-Host Disease

Belgium
Cliniques universitaires Saint-Luc- Université...
KU Leuven; University of Liege; University Hospital, Ghent; Universitair Ziekenhuis... and other collaborators

Recruiting

Study of Magnitude and Prediction of Response to Omalizumab and Mepolizumab in Adult Severe Asthma. (PREDICTUMAB)

Severe Asthma

Belgium
Angimmune LLC
University of Colorado, Denver; Washington University School of Medicine; Yale... and other collaborators

Unknown

Safety and Effectiveness of A-dmDT390-bisFv(UCHT1) Fusion Protein in Subjects With Mycosis Fungoides (Resimmune®)

Mycosis Fungoides
Columbia University
Boston University; National Institute on Drug Abuse (NIDA); Johns Hopkins University and other collaborators

Completed

Assessing Long-term CTN 0049 Outcomes, HCV Prevalence and Progression Along the HCV Care Continuum Among HIV/HCV Co-infected Substance Users in the U.S. (CTN 0064)

Hepatitis C | HIV | Substance Use | AIDS

United States
University of Liege
KU Leuven; Maastricht University Medical Center; University Hospital, Ghent; Queen... and other collaborators

Recruiting

Mesenchymal Stem Cell Infusion as Treatment for Steroid-Resistant Acute Graft Versus Host Disease (GVHD) or Poor Graft Function

Graft-versus-host Disease | Poor Graft Function | Low Donor T-cell Chimerism

Belgium, Netherlands
Cliniques universitaires Saint-Luc- Université...
University Hospital, Rouen; University Hospital, Montpellier; Central Hospital... and other collaborators

Unknown

Assessment of Regional Response With PET-FDG in Advanced Head and Neck Squamous Cell Carcinoma (pet)

Head and Neck Squamous Cell Carcinoma

Belgium
Memorial Sloan Kettering Cancer Center
The City College of New York; Queens Cancer Center of Queens Hospital; New York... and other collaborators

Recruiting

Meaning-Centered Counseling for Chinese Patients Who Are Being Treated for Advanced Cancer

Advanced Cancer

United States
Children's Hospitals and Clinics of Minnesota
M.D. Anderson Cancer Center; Washington University School of Medicine; Dana-Farber... and other collaborators

Recruiting

International PPB/DICER1 Registry

Neuroblastoma | Thyroid Carcinoma | Pineoblastoma | Wilms Tumor | Embryonal Rhabdomyosarcoma | Ovarian Sarcoma | Sertoli-Leydig Cell Tumor | Pleuropulmonary Blastoma | Gynandroblastoma | DICER1 Syndrome | Cystic Nephroma | Renal Sarcoma | Nodular Hyperplasia of Thyroid | Nasal Chondromesenchymal Hamartoma | Ciliary Body... and other conditions

United States
Universitaire Ziekenhuizen KU Leuven
University of Liege; University Hospital, Ghent; Imelda Hospital, Bonheiden; AZ... and other collaborators

Completed

Clinical Outcome After Escalation and De-escalation of Adalimumab in Real Life in Ulcerative Colitis (CEDAR UC)

Ulcerative Colitis

Belgium
University Hospital, Angers
Poitiers University Hospital; Hôpital Cochin; University Hospital, Grenoble; Cliniques... and other collaborators

Completed

Thromboembolic Risk Stratification by TRiP(Cast) Score to Guide Physicians in Preventive Treatment Prescriptions for Patients With Lower Limb Trauma Requiring Brace or castING. (CASTING)

Venous Thromboembolism | Lower Limb Trauma | Stratification

France, Belgium
Institute for Clinical and Experimental Medicine
King's College Hospital NHS Trust; Charles University, Czech Republic; Karolinska... and other collaborators

Completed

Endoscopic Pyloromyotomy for Refractory Gastroparesis (GREG)

Gastroparesis

United States, Czechia, Belgium, Denmark, Germany, Netherlands, Romania, Slovakia, Sweden, United Kingdom
National Cancer Institute (NCI)
M.D. Anderson Cancer Center; Washington University School of Medicine; Merck... and other collaborators

Completed

Phase I/II Adaptive Randomized Trial of Bevacizumab Versus Bevacizumab Plus Vorinostat in Adults With Recurrent Glioblastoma

Malignant Glioma | Recurrent Glioblastoma

United States
University of Padova
University Medical Center Groningen; Azienda Ospedaliera Universitaria Integrata... and other collaborators

Recruiting

European Prospective Registry on Anomalous Aortic Origin of the Coronary Arteries (EUROAAOCA)

Arrhythmia | Heart Defects, Congenital | Congenital Heart Disease | Sudden Cardiac Death | Surgical Procedure, Unspecified | Diagnosis | Adult Children | Coronary Artery Anomaly

Italy, Switzerland
Karolinska Institutet
University Health Network, Toronto; University of Chicago; University of Illinois... and other collaborators

Completed

Stockholm3 Validation Study in a Multi-Ethnic Cohort (SEPTA)

Prostate Cancer (Diagnosis)

United States, Canada
Maastricht University Medical Center
KU Leuven; University College, London; Erasmus Medical Center; Catholic University... and other collaborators

Active, not recruiting

IMMUNOtherapy and Stereotactic ABlative Radiotherapy (IMMUNOSABR) a Phase II Study (IMMUNOSABR2)

NSCLC Stage IV | Metastatic Disease

Netherlands, Belgium, United Kingdom, Germany, France, Italy
Wake Forest University
University of Missouri-Columbia; National Institute of Arthritis and Musculoskeletal... and other collaborators

Recruiting

The Osteoarthritis Prevention Study (TOPS)

Osteoarthritis, Knee

United States, Australia
Amoneta Diagnostics SAS
Assistance Publique - Hôpitaux de Paris; University Hospital, Geneva; University... and other collaborators

Unknown

ADDIA Proof-of-Performance Clinical Study (ADDIA)

Frontotemporal Lobar Degeneration | Progressive Supranuclear Palsy (PSP) | Dementia With Lewy Bodies (DLB) | Corticobasal Degeneration (CBD) | Alzheimer Disease (AD) | Parkinson Disease Dementia (PDD)

Belgium, France, Italy, Switzerland, Turkey
KU Leuven
University Medical Center Groningen; Maastricht University Medical Center; University... and other collaborators

Completed

Pulmonary Function Test Study - Automated Interpretation

Respiratory Disease

Belgium
Żelazna Medical Centre, LLC
Charles University, Czech Republic; Karolinska Institutet; Charite University... and other collaborators

Unknown

Risk Factors for Anxiety and Depression Among Pregnant Women During the COVID-19 Pandemic (MindCOVID)

Depression | Anxiety | Pregnancy Related

Lebanon, Hong Kong, United States, Sweden, Germany, Australia, Poland, Italy, Taiwan, Albania, Czechia, France, Israel, Norway, Spain
Universitair Ziekenhuis Brussel
UMC Utrecht; University Hospital, Antwerp; Imelda Hospital, Bonheiden; Cliniques... and other collaborators

Recruiting

Percutaneous Peritoneal Dialysis Catheter Insertion (PREDICT) (PREDICT)

End-stage Kidney Disease

Belgium, Netherlands
University Hospital, Ghent
Universitaire Ziekenhuizen KU Leuven; Jessa Hospital; Queen Fabiola Children's... and other collaborators

Completed

Vestibular Infants Screening-Flanders (VIS-Flanders)

Vestibular Disorder | Hearing Impaired Children

Belgium

Clinical Trials Sponsored by SPECNOVA LLC

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