Search clinical trials for: MAPK pathway

Total 1436 results

Ruijin Hospital
Shanghai Jiao Tong University School of Medicine

Unknown

The Feasibility and Safety of Instruments in Transanal Total Mesorectal Excision (TaTME) for Rectal Cancer (FSI-TaTME)

Postoperative Complications
Elfriede Bollschweiler

Completed

Cologne Esophageal Response Prediction Study (CERP-Study) (CERP)

Esophageal Cancer

Germany
Sheba Medical Center

Withdrawn

Safety and Efficacy Aspects of a Standardized Stepwise Anatomical Approach for AVNRT Ablation

Re-entrant Atrioventricular Node Tachycardia

Israel
San Diego Veterans Healthcare System
Pathway Genomics Corp

Unknown

PREDICT: Nutrigenetic Profile of Patients With Weight Loss Success (PREDICT)

Obesity
Memorial Sloan Kettering Cancer Center

Withdrawn

Detection of Acid Sphingomyelinase/Ceramide Pathway Activation in Radiotherapy Patients Using Intravoxel Incoherent Motion (IVIM) Diffusion-weighted Magnetic Resonance Imaging and Serum Biomarkers

Metastatic Disease to Bone | Metastatic Disease to Soft Tissue

United States
University Hospital, Montpellier
Institut de Recherche en Cancérologie de Montpellier (IRCM)

Unknown

Chemoresistance and Involvement of the NOTCH Pathway in Patients With Lung Adenocarcinoma (NOTCH)

Lung Adenocarcinoma

France
Assistance Publique - Hôpitaux de Paris
Agence Regionale de Sante d'Ile de France

Unknown

HCV Care Pathway in Ile-de-France (ParcoursVHC)

Hepatitis C Virus

France
Novartis Pharmaceuticals

Withdrawn

Study of Efficacy and Safety INC280 in Patients With Advanced Hepatocellular Carcinoma

Advanced Hepatocellular Carcinoma

Germany, Australia, Hong Kong, Switzerland, Spain, France, United States
Hospices Civils de Lyon

Completed

Investigation of Docosahexaenoic Acid (DHA) Metabolic Pathway in Human by Using 13C Labeled Molecules (AceDoPC)

Healthy Subject

France
Central Hospital, Nancy, France

Unknown

Study of Polyfunctionality of Anti-tumor T Lymphocytes in Cancerology: Potential Biomarker for Emerging Immunotherapies (POLYTCANCER)

Cancer
Fen Li

Unknown

Predictability Studies on the Efficacy of TNF-α Inhibitors in Chinese RA From "Real World"

Rheumatoid Arthritis
Kayseri Education and Research Hospital

Completed

Apoptotic Signaling Pathways in Rats With Endometrial Hyperplasia

Apoptotic Signal Pathways in Endometrial Hyperplasia

Turkey
Centre Hospitalier Universitaire Dijon

Unknown

Analysis of Transposon Control Pathways in Germinal Cancers of the Testicle (SEMINOMES)

Germinal Cancers of the Testicle

France
Dartmouth-Hitchcock Medical Center

Terminated

Effect of a Goal Setting Intervention on Exercise in Women With Metastatic Breast Cancer: An Exploration of The Lipogenic Pathway

Metastatic Breast Cancer

United States
Pfizer

Completed

Dose Escalation Study of PF-06741086 In Healthy Subjects

Healthy

Belgium
Vanderbilt University

Completed

The Utility of Clinical Milestones Pathway in a Cardiovascular ICU

Cardiac Surgery
Centre Hospitalier Universitaire Dijon

Completed

Study of the Effect of Beta-3 Adrenergic Receptor Agonists on Oxidative Stress and Signalling Pathways Implicated in Remodelling of the Uteroplacental Space: Experimental in Vitro Approach on Myometrial Tissue Explants (STRESSOX)

Pregnancy

France
Institut Claudius Regaud

Unknown

From the Characterization of the Cholesterol-epoxide Pathway Deregulation to New Therapeutic Perspectives in Breast Cancers (BREASTEROL)

Breast Cancer

France
The George Institute for Global Health, China

Completed

Clinical Pathways for the Management of Acute Coronary Syndromes - Phase 3,CPACS-3 (CPACS-3)

Acute Coronary Syndromes

China
Assistance Publique Hopitaux De Marseille

Unknown

Impact of Clinical Care Pathway on Prognosis and Therapeutic Medical Care of Infective Endocarditis

Infective Endocarditis (IE)

France
National Heart, Lung, and Blood Institute (NHLBI)

Completed

PATHWAYS--FULL SCALE STUDY

Cardiovascular Diseases | Obesity | Sedentary Behaviors
Catabasis Pharmaceuticals

Completed

Pilot Study To Assess CAT-2003 in Patients With Hyperlipidemia (PATHWAYS I)

Dyslipidemia | Hypercholesterolemia | Hypertriglyceridemia

United States, Canada
AstraZeneca

Completed

Phase I Open Label Dose Escalation Study to Investigate the Safety & Pharmacokinetics of AZD5312 in Patients With Androgen Receptor Tumors

Advanced Solid Tumours With Androgen Receptor Pathway as a Potential Factor

United Kingdom, United States
University of Aarhus

Unknown

The Complement Lectin Pathway After Cardiac Arrest

Out-of-Hospital Cardiac Arrest | Post Cardiac Arrest Syndrome

Denmark
National Cancer Institute (NCI)

Terminated

Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Stage IV Melanoma

Recurrent Melanoma | Stage IV Melanoma | Acral Lentiginous Malignant Melanoma | Lentigo Maligna Malignant Melanoma | Nodular Malignant Melanoma | Solar Radiation-related Skin Melanoma | Superficial Spreading Malignant Melanoma

United States
University Hospital, Clermont-Ferrand

Unknown

Exploration of Mesocorticolimbic Pathway in Impulse Control Disorders in Parkinson's Disease: Study Using Tensor Diffusion Imaging and Tractography. (TCI-IRMdiff)

Parkinson's Disease | Impulse Control Disorders

France
Sir Run Run Shaw Hospital

Unknown

Laparoscopy Combined With Enhanced Recovery Pathway

Crohn's Disease

China
EMD Serono

Terminated

Efficacy, Safety, and Tolerability of Plovamer Acetate (Pathway 1)

Relapsing Remitting Multiple Sclerosis

United States, Croatia, Bulgaria, Czech Republic, Italy, Mexico, Russian Federation, South Africa, Spain, Turkey, Hungary, Poland, Ukraine, Finland, United Kingdom, Greece, Serbia
RTI International

Completed

Coping Strategies Used by Food Insecure Households

Food Insecurity

United States
Bracane Company
IFG Medical

Terminated

Identify Genetic Variations That Affect The Ability of Patients To Metabolize Drugs Through Metabolic Pathways

Cardiovascular Disease | Chronic Disease | Endocrine System Disease | Respiratory Tract Disease | CNS Metabolic Disorders

United States
Queen's University
Ontario Ministry of Health and Long Term Care; Ontario Hospital Association

Completed

Evaluation of the Emergency Department Asthma Care Project

Asthma

Canada
Mahidol University

Completed

The Additive Anti-inflammatory Effect of Simvastatin in Combination With Inhaled Corticosteroids on p38 MAPK in Asthma (Simvastatin)

Asthma

Thailand
Centre Hospitalier Universitaire de Saint Etienne
Pfizer

Completed

Tissue Factor Pathway Inhibitor (TFPI) and Haemorrhagic Manifestations in Haemophilia A and B Patients

Hemophilia

France
National Cancer Institute (NCI)

Completed

AZD2171 in Treating Young Patients With Recurrent, Progressive, or Refractory Primary CNS Tumors

Recurrent Childhood Medulloblastoma | Recurrent Childhood Ependymoma | Childhood Atypical Teratoid/Rhabdoid Tumor | Childhood Grade I Meningioma | Childhood Grade II Meningioma | Childhood Grade III Meningioma | Childhood Infratentorial Ependymoma | Childhood Supratentorial Ependymoma | Recurrent Childhood... and other conditions

United States
Novartis Pharmaceuticals

Terminated

EXPLAIN -FragilE X Registry: An exPlorative Longitudinal Study for chAracterIzation, Treatment Pathways and patieNt-related Outcomes (EXPLAIN)

Fragile-X Syndrome

Germany
Assiut University

Completed

Expression of EPK in Recurrent Miscarriage (EPK-RM)

Recurrent Miscarriage

Egypt
Medical Research Council
Merck Sharp & Dohme LLC; Aarhus University Hospital; NCRI Clinical Studies Groups and other collaborators

Unknown

Evaluation Of The Treatment Effectiveness Of Glioblastoma / Gliosarcoma Through The Suppression Of The PI3K/Akt Pathway In Compared With MK-3475

Glioblastoma

United States, Italy, Belgium, Germany, Poland, Russian Federation, Spain, Switzerland, Ukraine, United Kingdom
Hunan Province Tumor Hospital

Unknown

Polymorphisms in Key Genes of Glycolytic Pathway: Influence on Radiosensitivity in Nasopharyngeal Carcinoma

Nasopharyngeal Carcinoma | Radiosensitivity | Single Nucleotide Polymorphisms

China
Children's Hospital of Eastern Ontario
CHAMO Innovation Fund

Completed

The Impact of Implementing a Nursing-driven Clinical Pathway for Inpatient Management of Children With Asthma (NAP)

Asthma

Canada
Rigshospitalet, Denmark
Bispebjerg Hospital

Completed

Autonomic Nervous Activity During the Systemic Inflammatory Response in Trained and Untrained Healthy Volunteers

Systemic Inflammatory Response Syndrome

Denmark
University Hospital Tuebingen

Completed

Compliance of Clinical Pathways in Elective Laparoscopic Cholecystectomy: Evaluation of Different Implementation Methods

Gallstones
Assistance Publique - Hôpitaux de Paris

Unknown

The OMAGE (Optimization of Medication in AGEd) Transitional Care-Pathway: Impact on Readmissions (OMAGE-P)

Ageing
Virginia Commonwealth University
National Institute on Minority Health and Health Disparities (NIMHD); Pathways-VA...

Terminated

Wellness Engagement Project, Petersburg (WE)

Obesity

United States
Autonomic Technologies, Inc.

Completed

Sphenopalatine Ganglion Stimulation for the Acute Treatment of Cluster Headache

Chronic Cluster Headache

Germany, Belgium, Denmark, Spain
Universitaire Ziekenhuizen KU Leuven

Completed

Effect of the Motilin Receptor Agonist, Erythromycin, on Hunger and Food Intake; Study of Role of Cholinergic Pathways

Healthy
National Cancer Institute (NCI)

Terminated

RO4929097and Bevacizumab in Treating Patients With Progressive or Recurrent Malignant Glioma

Adult Anaplastic Astrocytoma | Adult Anaplastic Oligodendroglioma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Recurrent Adult Brain Tumor

United States
National Cancer Institute (NCI)
M.D. Anderson Cancer Center

Terminated

RO4929097 in Treating Patients With Advanced Non-Small Cell Lung Cancer Who Have Recently Completed Treatment With Front-Line Chemotherapy

Stage IIIB Non-small Cell Lung Cancer | Recurrent Non-small Cell Lung Cancer | Stage IV Non-small Cell Lung Cancer

United States
Fundación para el Fomento de la Investigación Sanitaria...

Unknown

Clinical Pathway Based on Procalcitonin Levels for the Management of Community-acquired Pneumonia in Outpatients

Community-acquired Pneumonia

Spain
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Decision Making About Participating in Pharmacokinetic Studies in Patients Enrolled in a Phase I Treatment Clinical Trial

Unspecified Childhood Solid Tumor, Protocol Specific | Leukemia | Brain and Central Nervous System Tumors | Unspecified Adult Solid Tumor, Protocol Specific
Novartis Pharmaceuticals

Completed

Efficacy, Safety and Pharmacokinetics of Oral LDE225 in Treatment of Patients With Nevoid Basal Cell Carcinoma Syndrome (NBCCS)

Nevoid Basal Cell Carcinoma Syndrome | Basal Cell Carcinoma | Gorlin Syndrome

Belgium, Austria, Germany, Canada

Search clinical trials for: MAPK pathway

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