Clinical Trials Sponsored by P.R.I.S.M.A.-CRO

Total 12150 results

Boryung Pharmaceutical Co., Ltd
Samsung Medical Center; Asan Medical Center; Seoul National University Hospital; Seoul National University Bundang Hospital and other collaborators

Completed

Antihypertensive Efficacy and Tolerability and Determine the Adequate Antihypertensive Dosage of Fimasartan in Mild to Moderate Essential Hypertension Patients

Hypertension

Korea, Republic of
Peking Union Medical College Hospital
Peking University People's Hospital; Beijing Friendship Hospital; Cancer Institute... and other collaborators

Unknown

Multicenter, Prospective, RCT：Investigation of Combined Modality Therapy for Locally Advanced Mid/Low Rectal Cancer.

Rectal Cancer, Adenocarcinoma | Neoadjuvant Chemoradiation
University Hospital, Caen
Hospices Civils de Lyon; Centre Hospitalier Universitaire de Saint Etienne; Saint... and other collaborators

Not yet recruiting

Subcutaneous Cardiac Monitoring of Patients With BTK Inhibitors (IRAF-ISCM)

Atrial Fibrillation

France
Tianjin Medical University Cancer Institute and...
Shanxi Province Cancer Hospital; Fifth Affiliated Hospital, Sun Yat-Sen University and other collaborators

Recruiting

Efficacy and Safety of AI-assisted Radiotherapy Contouring Software for Thoracic Organs at Risk

Breast Cancer | Esophageal Cancer | Lung Cancer

China
The George Institute for Global Health, China
Takeda; Medical Research Council; Department for International Development, United... and other collaborators

Completed

The Third, Intensive Care Bundle With Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial (INTERACT3)

Cardiovascular Diseases | Stroke | Central Nervous System Diseases | Hypertension | Diabetes | Hemorrhage | Intracranial Hemorrhages | Cerebral Hemorrhage | Anticoagulant-induced Bleeding | Cerebral Vascular Disorder | Brain Disorder

China
Shenzhen Raysight Intelligent Medical Technology...
Renmin Hospital of Wuhan University; Sir Run Run Shaw Hospital; Jieyang People... and other collaborators

Not yet recruiting

Angiography-Derived Quantitative Functional Assessment Versus Pressure-Derived FFR and IMR: The FAIR Study

Ischemia | Heart Diseases | Cardiovascular Diseases | Vascular Diseases | Coronary Artery Disease | Arteriosclerosis | Coronary Stenosis
Peking University People's Hospital
Sun Yat-sen University; Cancer Institute and Hospital, Chinese Academy of Medical... and other collaborators

Unknown

Sentinel Lymph Node Mapping In Cervical Cancer (SLNMICC)

Uterine Cervical Neoplasms

China
Peking University People's Hospital
Sun Yat-sen University; Cancer Institute and Hospital, Chinese Academy of Medical... and other collaborators

Unknown

Sentinel Lymph Node Mapping In Endometrial Cancer (SLNMIEC)

Endometrial Neoplasms

China
The First Affiliated Hospital of Soochow University
The First Affiliated Hospital with Nanjing Medical University; The Affiliated... and other collaborators

Recruiting

Anti-FLT3 CAR T-cell Therapy in FLT3 Positive Relapsed/Refractory Acute Myeloid Leukemia

Acute Myeloid Leukemia

China
GeneScience Pharmaceuticals Co., Ltd.
The First Affiliated Hospital with Nanjing Medical University; Changhai Hospital and other collaborators

Active, not recruiting

Clinical Study of Genakumab for Injection in Patients With Acute Gout

Acute Gout

China
China National Biotec Group Company Limited
Peking University; Shaanxi Provincial Center for Disease Control and Prevention and other collaborators

Unknown

Evaluation of the Safety and Immunogenicity of Hepatitis A Vaccine

Vaccination

China
Shandong Qilu Stem Cells Engineering Co., Ltd.
First Affiliated Hospital of Fujian Medical University; Shanghai Public Health... and other collaborators

Unknown

Clinical Trial of Umbilical Cord Mesenchymal Stem Cell Transfusion in Decompensated Liver Cirrhosis

Decompensated Liver Cirrhosis
Shanghai Institute of Planned Parenthood Research
Fudan University; International Peace Maternity and Child Health Hospital; Shanghai... and other collaborators

Completed

Effectiveness of BenZalkonium Chloride Gel as Vaginal Contraceptive: a Multicentric Randomized Controlled Trial (BZK)

Healthy

China
GeneScience Pharmaceuticals Co., Ltd.
Peking University First Hospital; Peking Union Medical College Hospital; Children... and other collaborators

Unknown

A Study to Evaluate the Efficacy and Safety of Recombinant Human Growth Hormone Injection in Patients With Prader-Willi Syndrome

Prader-Willi Syndrome

China
Chengdu CoenBiotech Co., Ltd
Jiangsu Province Centers for Disease Control and Prevention; Changde First... and other collaborators

Recruiting

Clinical Trial to Explore the Skin Test Dosage of EEC in People Aged 18 to 65 Years Old and the Safety and Preliminary Efficacy in People Aged 3 to 75 Years Old.

Tuberculosis

China
University Hospital Tuebingen
European Space Agency; Dr. Isabelle Mack, Co-PI, University Hospital Tübigen; Dr. Claude Lambert, University Hospital of Saint-Etienne and other collaborators

Recruiting

A Counter Measure for the Effects of Immune and Microbiome Changes in Environments With Limited ANtigen Diversity (ICELAND-TWO) (ICELAND-2)

Confinement and Isolation

Antarctica
China Academy of Chinese Medical Sciences
Chengdu University of Traditional Chinese Medicine; Beijing Children's Hospital and other collaborators

Completed

Chinese Medicinal Treatment on Mild Hand, Foot, and Mouth Disease: Multicenter, Prospective, Randomized Double-blind, Placebo-controlled Study

Hand, Foot and Mouth Disease

China
Funan Liu
Institute of Health and Medical Technology, Hefei Institutes of Physical... and other collaborators

Recruiting

A Clinical Study Aims to Assess the Consistency of Clinical Efficacy in Colorectal Cancer Treatment and Drug Susceptibility Outcomes Using a Novel Drug Susceptibility Testing Method

Colorectal Cancer | Organoids

China
Ahn-Gook Pharmaceuticals Co.,Ltd
Samsung Medical Center; Seoul St. Mary's Hospital; Seoul National University... and other collaborators

Completed

Clinical Trial to Evaluate the Safety and Efficacy of AGR Tablet as a Treatment of Perennial Allergic Rhinitis in Korean

Allergic Rhinitis | Perennial Allergic Rhinitis | Non-seasonal Allergic Rhinitis

Korea, Republic of
Funan Liu
Institute of Health and Medical Technology, Hefei Institutes of Physical... and other collaborators

Recruiting

A Clinical Study Aims to Assess the Consistency of Clinical Efficacy in Gastric Cancer Treatment and Drug Susceptibility Outcomes Using a Novel Drug Susceptibility Testing Method

Gastric Cancer | Organoids

China
GeneScience Pharmaceuticals Co., Ltd.
Children's Hospital of Fudan University; The First Affiliated Hospital of Henan... and other collaborators

Unknown

Pegylated Somatropin (PEG Somatropin) in the Treatment of Children With Growth Hormone Deficiency

Growth Hormone Deficiency

China
Shenzhen Ausa Pharmed Co.,Ltd
Peking University First Hospital; The First Affiliated Hospital of Shanxi Medical... and other collaborators

Not yet recruiting

China Stroke Primary Prevention Trial for Subjects With H-type Hypertension and MTHFR 677 CC/CT Genotype (CSPPT2-CC/CT)

Hypertension

China
The First Affiliated Hospital of Soochow University
Affiliated Hospital of Jiangnan University; Chia Tai Tianqing Pharmaceutical... and other collaborators

Unknown

Anlotinib Hydrochloride Combined With EGFR TKIs in Advanced Non-small Cell Lung Cancer

Non-Small-Cell Lung

China
Techpool Bio-Pharma Co., Ltd.
The First Affiliated Hospital with Nanjing Medical University; Peking Union... and other collaborators

Suspended

Ulinastatin in Severe Acute Pancreatitis

Pancreatitis

China
Children's Hospital of Fudan University
Health Science Center of Xi'an Jiaotong University; Xiamen Children's Hospital and other collaborators

Recruiting

The Brain Mechanism of Social Emotion and Communication in Infants Aged 0 to 6 Years

Brain Development | Behavior Disorders, Child | Intellectual Developmental Disorders

China
Shenzhen Ausa Pharmed Co.,Ltd
Peking University First Hospital; The First Affiliated Hospital of Shanxi Medical... and other collaborators

Not yet recruiting

China Stroke Primary Prevention Trial for Subjects With Hypertension and MTHFR 677 TT Genotype (CSPPT2-TT) (CSPPT2-TT)

Hypertension

China
Central Hospital, Nancy, France
Sanofi; GlaxoSmithKline; Zambon SpA; Laboratoires URGO; Pierre Fabre Medicament; Bi... and other collaborators

Unknown

Allergy to Neuromuscular Blocking Agents and Pholcodine Exposure (ALPHO)

Neuromuscular Blocking Agents Anaphylaxis

France
The First Affiliated Hospital of Soochow University
The First Affiliated Hospital with Nanjing Medical University; The Affiliated... and other collaborators

Recruiting

Sequential Infusion of CD19 and BCMA CAR-T Cells to Improve PTR in Patients With AL

Platelet Transfusion Refractoriness | Acute Leukemia in Remission

China
Xijing Hospital
Xi'an Central Hospital; Second Affiliated Hospital of Xi'an Jiaotong University and other collaborators

Completed

Effectiveness and Safety of Berberine Hydrochloride and Bifidobacterium in People With Abnormal Glucose Level

Berberine Hydrochloride
Boryung Pharmaceutical Co., Ltd
Samsung Medical Center; Seoul National University Hospital; Gachon University... and other collaborators

Completed

Clinical Trial to Assess the Immunogenicity and Safety of the Vero Cell-derived JE Vaccine in Korea

Japanese Encephalitis

Korea, Republic of
GeneScience Pharmaceuticals Co., Ltd.
The First Affiliated Hospital with Nanjing Medical University; Tongji Hospital and other collaborators

Active, not recruiting

A Study Extension Period of PEG-somatropin (Pegylated-somatropin) in the Treatment of Children With Idiopathic Short Stature

Dwarfism

China
Nanjing NingQi Medicine Science and Technology...
The First Affiliated Hospital with Nanjing Medical University; Fudan University and other collaborators

Unknown

Yiqi Wenjing Prescriptions Preventive Efficacy of Oxaliplatin-induced Peripheral Neuropathy Clinical Trial (YWPPEOPNCT)

Colorectal Cancer | Chemotherapy-induced Peripheral Neuropathy
GeneScience Pharmaceuticals Co., Ltd.
The First Affiliated Hospital with Nanjing Medical University; Tongji Hospital and other collaborators

Unknown

A Study of PEG-somatropin in the Treatment of Children With Idiopathic Short Stature

Dwarfism

China
The First Affiliated Hospital of Soochow University
Affiliated Hospital of Jiangnan University; The Affiliated Nanjing Drum Tower... and other collaborators

Recruiting

CD7 CAR T-cell for R/R CD7+ T Cell Lymphoma

Refractory and Relapsed T Cell Lymphoma

China
Peijia Medical Technology (Suzhou) Co., Ltd.
General Hospital of Shenyang Military Region; West China Hospital; Second Affiliated... and other collaborators

Active, not recruiting

Safety and Efficacy of TaurusOne® Transcatheter Aortic Valve System in Patients With Severe Calcific Aortic Stenosis

Aortic Stenosis

China
Xinqiao Hospital of Chongqing
Chongqing University Cancer Hospital; 920th Hospital of Joint Logistics Support... and other collaborators

Not yet recruiting

CD19 and CD22 Dual-targeted CAR-T Cells for Relapsed or Refractory B-NHL

B-cell Lymphoma Refractory | B-cell Lymphoma Recurrent

China
I.C. Van Gelder
Bayer; AstraZeneca; Boehringer Ingelheim; Boston Scientific Corporation; Medtronic; Abbott Medical Devices and other collaborators

Completed

Routine Versus Aggressive Upstream Rhythm Control for Prevention of Early Atrial Fibrillation in Heart Failure (RACE 3)

Atrial Fibrillation

United Kingdom, Netherlands
International Agency for Research on Cancer
Federico II University; Imperial College London; Fondazione IRCCS Istituto Nazionale... and other collaborators

Completed

Discovery of Novel Biomarkers of Dietary Exposure in the EPIC Calibration Study

Dietary Exposure
Sun Yat-sen University
First Affiliated Hospital, Sun Yat-Sen University; Nanfang Hospital of Southern... and other collaborators

Completed

Comparison of Intravenous Anesthetics to Volatile Anesthetics on Postoperative Cognitive Dysfunction

Intra-abdominal and Intrapelvic Surgery

China
Shenzhen Beike Bio-Technology Co., Ltd.
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical... and other collaborators

Unknown

Safety and Efficacy of Umbilical Cord Mesenchymal Stem Cell Therapy for Patients With Hereditary Ataxia

Hereditary Ataxia

China
Shenzhen Beike Bio-Technology Co., Ltd.
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical... and other collaborators

Unknown

Safety and Efficacy of Umbilical Cord Mesenchymal Stem Cell Therapy for Patients With Progressive Multiple Sclerosis and Neuromyelitis Optica

Progressive Multiple Sclerosis | Neuromyelitis Optica.

China
Shenzhen Kangzhe Pharmaceutical Co., Ltd.
LanZhou University; Beijing Friendship Hospital; The Third Affiliated Hospital... and other collaborators

Recruiting

A Multicentre Study to Explore the Efficacy and Safety of Mucopolysaccharide Polysulfate Cream in Patients With Eczema

Eczema

China
Boston University
Harvard Medical School (HMS and HSDM); University of Colorado, Denver; National... and other collaborators

Recruiting

Efficacy and Tolerability of Bedaquiline, Delamanid, Levofloxacin, Linezolid, and Clofazimine to Treat MDR-TB (DRAMATIC)

Tuberculosis, Multidrug-Resistant

Philippines, Vietnam
Shanghai Eye Disease Prevention and Treatment Center
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine; Shanghai... and other collaborators

Completed

The Effectiveness and Safety of Low-intensity Single-wavelength Red Light in Controlling High Myopia in Children and Adolescents：A Randomized, Controlled, Multicenter Clinical Trial

Age 3 to 16 Years (Inclusive), Male or Female | Clinical Diagnosis Confirming That Myopia Has Occurred in at Least One Eye | The Guardian Voluntarily Signed the Subject's Informed Consent Form

China
Boryung Pharmaceutical Co., Ltd
Pusan National University Hospital; Ulsan University Hospital; Daegu Catholic... and other collaborators

Completed

The Clinical Study to Evaluate the Efficacy and Safety of Fimasartan in Patients With Mild to Moderate Essential Hypertension

Hypertension

Korea, Republic of
Shenzhen Ausa Pharmed Co.,Ltd
Peking University First Hospital; Nanfang Hospital of Southern Medical University and other collaborators

Unknown

H-Type Hypertension Precision Medicine Trial

Hypertension

China
Eastern Hepatobiliary Surgery Hospital
Sun Yat-sen University; Shanghai Zhongshan Hospital; First Affiliated Hospital... and other collaborators

Unknown

Effect of Babaodan on Tumor Recurrence After Curative Resection of Hepatocellular Carcinoma

Hepatocellular Carcinoma | Tumor Recurrence
Xinqiao Hospital of Chongqing
Chongqing University Cancer Hospital; 920th Hospital of Joint Logistics Support... and other collaborators

Not yet recruiting

Anti-CD19 FasT CAR-T Cell Therapy for B Cell NHL

Lymphoma, Non-Hodgkin

China
Finnish Institute for Health and Welfare
Karolinska Institutet; Medical University of Vienna; University Of Perugia; Maastricht... and other collaborators

Active, not recruiting

Digitally Supported Lifestyle Programme to Promote Brain Health Among Older Adults (LETHE)

Cognitive Impairment | Dementia | Cognitive Decline

Sweden, Austria, Finland, Italy
Shandong Branden Med.Device Co.,Ltd
Wuhan University; Hubei Cancer Hospital; Yichang Central People's Hospital; Wuhan... and other collaborators

Not yet recruiting

Comparing the Safety and Effectiveness of Tunnel PICC Guided by EDUG and Conventional PICC (PICC)

the Incidence of PICC-related Complications

Clinical Trials Sponsored by P.R.I.S.M.A.-CRO

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