Search clinical trials for: Type 2 Hybrid Effectiveness-Implementation Trial

Total 126826 results

Nantes University Hospital

Recruiting

Prospective Multicenter Randomized and Controlled Study Evaluating the Benefit of Early Pulmonary Vein Isolation Compared to Usual Treatment in Patients Aged Over 75 Years and Presenting With Atrial Fibrillation (EDearly AF)

Atrial Fibrillation

France
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Radiolabeled Monoclonal Antibody Therapy, Combination Chemotherapy, and Bevacizumab in Treating Patients With Metastatic Colorectal Cancer

Stage IV Colon Cancer | Stage IV Rectal Cancer | Recurrent Colon Cancer | Recurrent Rectal Cancer

United States
Janssen Research & Development, LLC

Active, not recruiting

An Efficacy and Safety Study of Erdafitinib (JNJ-42756493) in Participants With Urothelial Cancer

Urothelial Cancer

United States, France, Germany, United Kingdom, Belgium, Taiwan, Spain, Israel, India, Romania, Korea, Republic of, Russian Federation, Turkey, Austria, Moldova, Republic of
UCB Biopharma SRL

Completed

A Study to Test the Efficacy and Safety of Bimekizumab in the Treatment of Subjects With Active Psoriatic Arthritis (BE OPTIMAL)

Psoriatic Arthritis

United States, Australia, Belgium, Canada, Czechia, France, Germany, Hungary, Italy, Japan, Poland, Russian Federation, Spain, United Kingdom
Janssen Research & Development, LLC

Active, not recruiting

An Efficacy and Safety Study of Niraparib in Men With Metastatic Castration-Resistant Prostate Cancer and DNA-Repair Anomalies (Galahad)

Prostatic Neoplasms

United States, Australia, France, United Kingdom, Belgium, Taiwan, Spain, Israel, Netherlands, Sweden, Korea, Republic of, Canada, Russian Federation, Brazil, Denmark
GlaxoSmithKline

Completed

A Study of GSK3228836 in Participants With Chronic Hepatitis B (CHB) (B-Clear)

Hepatitis B

United States, Germany, Korea, Republic of, Spain, Taiwan, Bulgaria, Italy, Russian Federation, Thailand, Canada, Singapore, France, Malaysia, China, Romania, Hong Kong, Philippines, Japan, Poland, South Africa, United Kingdom, Ar...
Federation Francophone de Cancerologie Digestive

Active, not recruiting

Standard Chemotherapy vs Immunotherapie in 2nd Line Treatment of MSI Colorectal Mestastatic Cancer (SAMCO)

Metastatic Colorectal Cancer | MSI

France
Teva Branded Pharmaceutical Products R&D, Inc.

Terminated

A Study to Evaluate the Long-term Safety, Tolerability and Effect of Daily Oral Laquinimod 0.6 mg on Disease Course in Subjects With Relapsing Multiple Sclerosis

Relapsing Multiple Sclerosis

United States, Bulgaria, Croatia, Czechia, Estonia, Georgia, Germany, Israel, Italy, Lithuania, North Macedonia, Poland, Romania, Russian Federation, Slovakia, South Africa, Spain, Ukraine
GlaxoSmithKline

Completed

An Observational Study For Ambrisentan (VOLT)

Hypertension, Pulmonary

France, Netherlands, Spain, Germany, Sweden, Australia, United Kingdom, Belgium, Canada, Italy, Greece, Slovakia, Norway, Czech Republic, Denmark
Eisai Inc.

Completed

Assessing The Long-Term Safety And To Explore The Long-Term Efficacy Of Zonisamide As Monotherapy In Newly Diagnosed Partial Seizures

Epilepsy

Greece, Italy, Spain, Sweden, Korea, Republic of, Germany, Australia, France, Switzerland, Slovakia, Poland, Taiwan, Hungary, Serbia, India, United Kingdom, Denmark, Russian Federation, South Africa, Montenegro
Vertex Pharmaceuticals Incorporated

Completed

A Study of Lumacaftor in Combination With Ivacaftor in Cystic Fibrosis Subjects Aged 12 Years and Older Who Are Homozygous for the F508del-CFTR Mutation (TRAFFIC)

Cystic Fibrosis, Homozygous for the F508del CFTR Mutation

United States, Germany, Canada, Netherlands, Czech Republic, Italy, Ireland, Sweden, United Kingdom, Australia, France
AbbVie (prior sponsor, Abbott)

Completed

Efficacy and Safety of Adalimumab and Methotrexate (MTX) Versus MTX Monotherapy in Subjects With Early Rheumatoid Arthritis (PREMIER)

Early Rheumatoid Arthritis

United States, Australia, Austria, Belgium, Canada, Czech Republic, Denmark, Finland, France, Germany, Ireland, Italy, Netherlands, Norway, Slovakia, Spain, Sweden, Switzerland, United Kingdom
Drug Induced Liver Disease Study Group
Unimed Scientific Inc.

Completed

A Retrospective Study on Drug Induced Liver Injury in China (DILI-R)

Drug-Induced Liver Injury

China
Medtronic Cardiac Rhythm and Heart Failure

Active, not recruiting

Cryo Global Registry

Atrial Fibrillation

Japan, Korea, Republic of, Singapore, China, Taiwan, Thailand, India, Switzerland, Germany, United States, Malaysia, United Kingdom, Indonesia, Hungary, Chile, United Arab Emirates, Czechia, Italy, Belgium, Poland, Iceland, Slovakia, Argenti... and more
Janssen Pharmaceutica N.V., Belgium

Recruiting

A Study of Adding Apalutamide to Radiotherapy and LHRH Agonist in High-Risk Patients With Hormone-Sensitive Prostate Cancer (PRIMORDIUM)

Prostatic Neoplasms

Italy, Russian Federation, Brazil, Portugal, Belgium, Spain, United States, Austria, Hungary, Turkey, Germany, Australia, Poland, Mexico, Finland, Slovakia, Lebanon, Czechia, Denmark, Jordan, Sweden
Bayer

Completed

A Study to Evaluate Efficacy and Safety of Oral BAY63-2521 in Patients With CTEPH. (CHEST-1)

Pulmonary Hypertension

Belgium, France, Spain, Turkey, Portugal, Taiwan, Japan, United States, Switzerland, Korea, Republic of, Austria, Canada, China, Denmark, Germany, Russian Federation, Mexico, Argentina, Netherlands, Italy, Poland, United Kingdom, Au... and more
AstraZeneca

Completed

Efficacy of Ciclesonide vs Fixed Combination of Fluticasone Propionate/Salmeterol vs Placebo in Patients With Mild Persistent Asthma (12 to 75 y) (BY9010/M1-132)

Asthma

Hungary, South Africa, Poland, Spain, Canada, Australia, Czech Republic
Hoffmann-La Roche

Completed

A Non-Interventional Study of Patients With Persistent Symptoms of Schizophrenia to Describe Medical Resource Utilization and Burden of Illness

Schizophrenia

Spain, Turkey, France, Russian Federation, Italy, Czech Republic, Australia
Novartis Pharmaceuticals

Terminated

Secukinumab Efficacy and Safety Study in Patients With Rheumatoid Arthritis and Inadequate Response to Anti-TNFα Agents. (REASSURE2)

Rheumatoid Arthritis

United States, Germany, Greece, Argentina, Brazil, Colombia, Czech Republic, Dominican Republic, Guatemala, India, Italy, Japan, Korea, Republic of, Panama, Portugal, South Africa
Takeda

Terminated

Safety and Efficacy Study of Ramelteon (TAK-375) Tablets for Sublingual Administration (SL) in Adults With Bipolar 1 Disorder

Bipolar Disorder

United States, Ukraine, United Kingdom, Germany, Bulgaria, Romania, Serbia, Russian Federation, Czech Republic, Poland
Genzyme, a Sanofi Company
Bayer

Completed

Comparison of Alemtuzumab and Rebif® Efficacy in Multiple Sclerosis, Study One (CARE-MS I)

Multiple Sclerosis, Relapsing-Remitting

Australia, France, United States, Germany, Canada, United Kingdom, Russian Federation, Argentina, Brazil, Croatia, Poland, Serbia, Sweden, Ukraine, Czech Republic, Mexico
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating Etanercept in the Treatment of Subjects With Psoriasis

Psoriasis

Belgium, France, Germany, Italy, Spain, United Kingdom, Switzerland, Greece, Netherlands, Sweden, Austria, Hungary, Denmark, Norway, Portugal, Turkey, Czech Republic, Finland, Poland
Janssen-Cilag International NV

Completed

A Study in Healthy Participants to Evaluate the Effects of Multiple Doses of JNJ-55308942 on Cytochrome P450 Substrate Activity and on the Pharmacokinetics of Levonorgestrel/Ethinyl Estradiol

Healthy

Belgium
University of Utah

Terminated

Docetaxel or Abiraterone Acetate With ADT in Treating Patients With Metastatic Hormone Sensitive Prostate Cancer (ACADEMIC)

Stage IV Prostate Cancer | Metastatic Prostatic Adenocarcinoma | Castration-Sensitive Prostate Carcinoma | Stage IVA Prostate Cancer | Stage IVB Prostate Cancer

United States
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Effect of Oral Doses of JNJ-54175446 on the Inhibition of Cytochrome P450 CYP3A4, CYP2C9, CYP1A2 and CYP2D6 Activity and the Induction of CYP2B6 and CYP2C19 Activity Using a Multiple Probe Substrate Cocktail in Healthy Subjects

Healthy

Belgium
United Therapeutics

Recruiting

A Study Evaluating the Efficacy and Safety of Ralinepag to Improve Treatment Outcomes in PAH Patients

Cardiovascular Diseases | Vascular Diseases | Lung Diseases | Hypertension | Connective Tissue Diseases | Pulmonary Arterial Hypertension | Familial Primary Pulmonary Hypertension | Hypertension, Pulmonary | Pulmonary Hypertension | PAH | Respiratory Tract Disease

United States, Australia, Austria, Italy, Taiwan, Spain, Korea, Republic of, Canada, United Kingdom, Singapore, Argentina, Germany, France, Belgium, Mexico, Brazil, Hungary, Bulgaria, Chile, Czechia, Denmark, Greece, Israel, Netherlands, Pola... and more
University of Pennsylvania
Hospira, now a wholly owned subsidiary of Pfizer

Completed

Alternative Sedation During Bronchoscopy (DEX)

Sedation

United States
National Cancer Institute (NCI)

Terminated

Docetaxel and Prednisone With or Without Vaccine Therapy in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer

Prostate Adenocarcinoma | Recurrent Prostate Carcinoma | Stage IV Prostate Cancer | Hormone-Resistant Prostate Cancer

United States
Janssen-Cilag International NV

Withdrawn

A Study of Esketamine Nasal Spray Plus a New Standard-of-care Oral Antidepressant or Placebo Nasal Spray Plus a New Standard-of-care Oral Antidepressant in Adult and Elderly Participants With Treatment-resistant Depression

Depressive Disorder, Treatment-Resistant
Ajay Wasan, MD, Msc
Mayo Clinic; National Institute of Arthritis and Musculoskeletal and Skin Diseases... and other collaborators

Recruiting

Treating Negative Affect in Low Back Pain Patients (TNA-LBP)

Chronic Low Back Pain | Negative Affectivity

United States
Akeso

Recruiting

A Phase III Study to Evaluate the Efficacy and Safety of AK111 in Subjects With Active Ankylosing Spondylitis

Ankylosing Spondylitis

China
University of Turin, Italy
Gilead Sciences

Recruiting

Burden of Hepatitis D Virus (HDV) Infection in Italy (HDV Describe)

Chronic Hepatitis D

Italy
SK Life Science, Inc.

Recruiting

Investigate Efficacy and Safety of Carisbamate as Adjunctive Treatment for Seizures Associated With LGS in Children and Adults

Seizures | Lennox Gastaut Syndrome

United States, Korea, Republic of, Taiwan, Colombia, Australia, Poland, Serbia, Mexico, Spain, Greece, Italy, Portugal, Germany, Argentina, Israel
Alimentiv Inc.
Takeda Development Center Americas, Inc.

Active, not recruiting

Determination of the Optimal Treatment Target in Ulcerative Colitis (VERDICT)

Colitis, Ulcerative

Canada, Italy, United Kingdom, Poland, Netherlands, Ukraine, Belarus, United States, Belgium, France
Swedish Orphan Biovitrum

Active, not recruiting

A 48-Month Study to Evaluate Long-Term Effectiveness of Elocta on Joint Health (A-MORE)

Hemophilia A

Spain, Germany, Czechia, Italy, Estonia, Finland, Greece, Netherlands, Saudi Arabia, Slovenia, Sweden, Switzerland, United Kingdom
Ionis Pharmaceuticals, Inc.

Completed

Safety and Tolerability Study of ISIS EIF4E Rx in Combination With Docetaxel and Prednisone (CRPC)

Castrate-Resistant Prostate Cancer

United States, Puerto Rico, Hungary, Romania, Russian Federation, Poland
Fresenius Kabi SwissBioSim GmbH

Completed

A Study to Evaluate the Efficacy, Pharmacodynamics, Safety, and Immunogenicity of FKS518 in Postmenopausal Women With Osteoporosis

Postmenopausal Osteoporosis

Hungary, Poland, Georgia, Bulgaria, Czechia, Estonia
Green Valley (Shanghai) Pharmaceuticals Co., Ltd.

Active, not recruiting

A Clinical Study to Evaluate the Long-Term Safety Sodium Oligomannate Capsules (GV-971)

Alzheimer Disease

China
Mitsubishi Tanabe Pharma America Inc.

Completed

Safety Study of Oral Edaravone Administered in Subjects With ALS

ALS

United States, Canada, Japan, France, Germany, Italy
Pfizer

Completed

Aromasin® Interventional Study Of Early Invasive Breast Cancer Patients In China

Breast Neoplasms

China
Pfizer

Completed

A Study Of Crizotinib Versus Chemotherapy In Previously Untreated ALK Positive East Asian Non-Small Cell Lung Cancer Patients

NSCLC (Non-small Cell Lung Cancer)

Hong Kong, China, Taiwan, Malaysia, Thailand
Eisai Limited

Terminated

Efficacy and Safety of Adjunctive Zonisamide in Myoclonic Seizures Associated With Idiopathic Generalised Epilepsy

Epilepsy

Australia, Serbia, Germany, Czech Republic, Romania, Estonia, Lithuania, Croatia, Finland, Hungary, Poland, Russian Federation, Ukraine
Boehringer Ingelheim

Completed

Non-Interventional Observational Study With Viramune Plus Antiretroviral in HIV Infected Patients

HIV Infections

Germany
Solvay Pharmaceuticals

Completed

Analgesic Effectiveness of Three Different Doses of a New Formulation of Lamaline in a Model of Painful Knee (Gonarthrosis)

Knee Osteoarthritis

France
Società Italiana di Cardiologia Invasiva
Eli Lilly and Company; Royal Brompton & Harefield NHS Foundation Trust; Biotronik...

Completed

CARESS in Acute Myocardial Infarction

Myocardial Infarction

France, Italy, Poland
University of Debrecen

Completed

Diclofenac Premedication, as the Effect of Preemptive Analgesia After Post-thoracotomy Chest and Shoulder Pain

Pain | Inadequate or Impaired Respiratory Function

Hungary
Takeda

Terminated

Extended Access Program of Vedolizumab IV in Ulcerative Colitis and Crohn's Disease

Crohn Disease | Colitis, Ulcerative

Korea, Republic of, Italy, India, Malaysia, Hungary, Serbia, Latvia, Australia, Estonia, Poland, South Africa, Czechia, Turkey, Bulgaria, New Zealand, Romania, Russian Federation, Ukraine
Italfarmaco
Cromsource

Enrolling by invitation

Givinostat in Duchenne's Muscular Dystrophy Long-term Safety and Tolerability Study

Duchenne Muscular Dystrophy

Spain, United States, Canada, Belgium, France, Israel, Italy, Netherlands, Serbia, Germany, United Kingdom
Cytokinetics

Completed

A Study for Patients Who Completed VITALITY-ALS (CY 4031) (VIGOR-ALS)

Amyotrophic Lateral Sclerosis (ALS)

United States, Netherlands, Canada, Belgium, United Kingdom, France, Germany, Ireland, Italy, Portugal, Spain
Hoffmann-La Roche
Genentech, Inc.

Completed

A Study to Evaluate the Efficacy and Safety of Rituximab Versus Mycophenolate Mofetil (MMF) in Participants With Pemphigus Vulgaris (PV)

Pemphigus Vulgaris

United States, Spain, Israel, Australia, France, Argentina, Canada, Turkey, Germany, Brazil, Italy, Ukraine

Search clinical trials for: Type 2 Hybrid Effectiveness-Implementation Trial

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