Search clinical trials for: Prospective observational open cohort study

Total 128808 results

Pharmacia and Upjohn

Completed

A Study of Different Doses of Atevirdine Mesylate Plus Zidovudine in HIV-Positive Patients

HIV Infections

United States
Hoffmann-La Roche

Completed

A Study of Saquinavir Soft Gel Capsules (SGC) Used in Combination With Two Other Anti-HIV Drugs in Patients With HIV-Associated Kidney Disease

HIV Infections | AIDS-Associated Nephropathy

United States
National Center for Research Resources (NCRR)
University of Utah

Terminated

Study of Metabolic Effects of Pregnancy in Women With Cystic Fibrosis

Cystic Fibrosis

United States
Pfizer

Completed

Comparative Randomized Study of the Efficacy, Safety, and Toleration of Fluconazole Oral Suspension or Nystatin Oral Suspension in the Treatment of Patients With Oropharyngeal Candidiasis in Association With the Acquired Immunodeficiency Syndrome

HIV Infections | Candidiasis, Oral

United States
Fairview University Medical Center

Unknown

Study of Pulmonary Complications in Pediatric Patients With Storage Disorders Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

Mucopolysaccharidosis I | Niemann-Pick Disease | Mucopolysaccharidosis VI | Wolman Disease | Adrenoleukodystrophy | Metachromatic Leukodystrophy | Pulmonary Complications | Fucosidosis | Globoid Cell Leukodystrophy | Gaucher's Disease | Mannosidosis | I Cell Disease

United States
National Eye Institute (NEI)

Completed

Branch Vein Occlusion Study

Macular Degeneration | Vitreous Hemorrhage | Neovascularization, Pathologic
Astra USA

Completed

A Multicenter Study of Oral Versus Intravenous Hydration in AIDS Patients With CMV Retinitis Treated With Foscavir (Foscarnet Sodium)

HIV Infections | Cytomegalovirus Retinitis

United States
Ribozyome

Completed

Gene Therapy in HIV-Positive Patients With Non-Hodgkin's Lymphoma

HIV Infections | Lymphoma, Non-Hodgkin

United States
National Center for Research Resources (NCRR)
University of California, Los Angeles

Completed

Phase III Randomized, Double-Blind, Placebo-Controlled Study of Dehydroepiandrosterone Replacement for Primary Adrenal Insufficiency

Addison's Disease
National Center for Research Resources (NCRR)
Yale University

Completed

Phase III Randomized, Double-Blind, Placebo-Controlled Study of Guanfacine for Tourette Syndrome and Attention Deficit Hyperactivity Disorder

Tourette Syndrome
Corixa Corporation
GlaxoSmithKline

Unknown

Safety and Efficacy Study of Iodine-131 Anti-B1 Antibody for Chronic Lymphocytic Leukemia

Chronic Lymphocytic Leukemia

United States
Astra USA

Completed

The Pilot Study of Foscarnet Cream in the Treatment of Mucocutaneous Herpes Simplex Virus Infections in Immunocompromised Patients Unresponsive to Acyclovir Treatment

HIV Infections | Herpes Simplex

United States
Pfizer

Completed

A Pilot Study of Fluconazole Plus Flucytosine for the Treatment of AIDS Patients With Acute Cryptococcal Meningitis.

HIV Infections | Meningitis, Cryptococcal

United States
Pfizer

Completed

A Randomized, Double-Blind, Comparative Study of Azithromycin Versus Clarithromycin in Combination With Ethambutol for the Treatment of Disseminated Mycobacterium Avium Complex (MAC) Infection in AIDs Patients

HIV Infections | Mycobacterium Avium-intracellulare Infection

United States
Newport Pharmaceuticals International

Completed

A Study of Isoprinosine in Patients With Severe AIDS

HIV Infections

United States
National Center for Research Resources (NCRR)
Ohio State University

Completed

Phase III Randomized, Double-Blind, Placebo-Controlled Study of Dichlorphenamide for Periodic Paralyses and Associated Sodium Channel Disorders

Paralysis, Hyperkalemic Periodic | Paramyotonia Congenita | Hypokalemic Periodic Paralysis
National Center for Research Resources (NCRR)
University of Alabama at Birmingham

Unknown

Phase III Randomized Study of Oral Acyclovir in Infants With Herpes Simplex Virus Infection Involving the Central Nervous System

Herpes Simplex

United States, Canada
Astra USA

Completed

Safety and Efficacy of Intravenous Magnesium Sulfate in Modulating Changes in Symptoms and Divalent Cation Levels Associated With Foscavir Therapy: A Phase IV Randomized, Double-Blind, Placebo-Controlled, Cross-Over, Pilot Study

HIV Infections | Hypocalcemia | Cytomegalovirus Infections

United States
National Center for Research Resources (NCRR)
Ann & Robert H Lurie Children's Hospital of Chicago

Completed

Study of the Relationship Between Calcium Levels and Intact Parathyroid Hormone (iPTH) in Adults With Repaired or Palliated Conotruncal Cardiac Defects

Heart Defects, Congenital | Tetralogy of Fallot | Pulmonary Valve Stenosis | Hypoparathyroidism | Pulmonary Atresia | Conotruncal Cardiac Defects
Community Research Initiative of New England

Completed

A Study to Evaluate the Effect of Cimetidine on CD4 Lymphocyte Counts in HIV Infection

HIV Infections

United States
Genentech, Inc.

Completed

A Phase I Study of Recombinant Human CD4 Immunoglobulin G (rCD4-lgG) in Patients With HIV-Associated Immune Thrombocytopenic Purpura

HIV Infections | Immune Thrombocytopenic Purpura ( ITP )

United States
National Center for Research Resources (NCRR)
University of Michigan

Completed

Pilot Study of Familial Nonsyndromal Mondini Dysplasia

Mondini Dysplasia

United States
National Eye Institute (NEI)

Unknown

The Collaborative Longitudinal Evaluation of Keratoconus (CLEK) Study

Keratoconus

United States
Johns Hopkins University

Completed

Pilot Study of Cyclophosphamide in Patients With Life-Threatening Systemic Lupus Erythematosus or Antiphospholipid Antibody Syndrome

Systemic Lupus Erythematosus | Antiphospholipid Antibody Syndrome

United States
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Neurodevelopmental and Neurological Study of Infants and Children With HIV-1 Infection and AIDS in Clinical Trials

HIV Infections

United States
Lederle Laboratories

Completed

A Randomized, Double-Blind, Placebo Controlled Study of l-Leucovorin in Combination With Trimethoprim / Sulfamethoxazole in the Therapy of Pneumocystis Carinii Pneumonia in Patients With the Acquired Immunodeficiency Syndrome

HIV Infections | Pneumonia, Pneumocystis Carinii

United States
Glaxo Wellcome

Completed

A Pilot Study To Evaluate the Effect of Retrovir (Zidovudine: AZT) in the Treatment of Human Immunodeficiency Virus (HIV) Associated Dementia and Neuromuscular Diseases

HIV Infections | Neuromuscular Diseases | AIDS Dementia Complex

United States
Pharmacia

Completed

Rifabutin Therapy for the Prevention of Mycobacterium Avium Complex (MAC) Bacteremia in HIV Positive Patients With CD4 Counts = or < 200: Treatment IND Study

HIV Infections | Mycobacterium Avium-intracellulare Infection

United States
Stanford University

Completed

A Dose-Escalating Study of Ro 31-8959 ( HIV Protease Inhibitor ) in Patients With HIV Disease.

HIV Infections

United States
Gilead Sciences

Completed

A Phase I/II Study of the Safety, Tolerance, and Pharmacokinetics of 9-(2-Phosphonylmethoxyethyl)Adenine ( PMEA; Adefovir ) in Patients With Advanced HIV Disease.

HIV Infections

United States
Gilead Sciences

Completed

A Study of PMPA in HIV-Infected Patients

HIV Infections

United States
Amgen

Completed

A Study of Granulocyte Colony-Stimulating Factor Plus Recombinant Erythropoietin Plus Zidovudine in Patients With AIDS or AIDS-Related Complex

HIV Infections | Cytopenias

United States
Pfizer

Completed

A Study of Fluconazole in the Prevention of Fungal Infections in HIV-Infected Patients Living in Areas Where Fungal Infections Are Common

HIV Infections | Mycoses | Coccidioidomycosis

United States
Glaxo Wellcome

Completed

A Study to Compare Two Anti-HIV Drug Combinations That Include Amprenavir in HIV-Infected Patients Who Have Failed Anti-HIV Drug Combinations That Did Not Include Amprenavir

HIV Infections

United States
National Center for Research Resources (NCRR)
Ann & Robert H Lurie Children's Hospital of Chicago

Completed

Phase II Study of Calcitonin for Tumoral Calcinosis

Calcinosis

United States
National Center for Research Resources (NCRR)
Penn State University

Completed

Phase II Pilot Study of Early Cortisol Replacement to Prevent Bronchopulmonary Dysplasia

Bronchopulmonary Dysplasia
National Center for Research Resources (NCRR)
Columbia University

Completed

Study of Low Bone Mass in Premenopausal or Perimenopausal Women

Osteoporosis

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Cooperative Study of The Clinical Course of Sickle Cell Disease

Anemia, Sickle Cell | Blood Disease
National Center for Research Resources (NCRR)
Icahn School of Medicine at Mount Sinai

Completed

Genetic Study of Patients and Families With Diaphyseal Medullary Stenosis With Malignant Fibrous Histiocytoma of the Bone

Stenosis | Histiocytoma

United States
Northwestern Memorial Hospital

Unknown

Phase I Study of Immune Ablation and CD34+ Peripheral Blood Stem Cell Support in Patients With Systemic Lupus Erythematosus

Systemic Lupus Erythematosus

United States
Sir Charles Gairdner Hospital

Unknown

Thyroxine Titration Study

Hypothyroidism

Australia
National Center for Research Resources (NCRR)
Vanderbilt University Medical Center

Completed

Phase II Randomized, Double-Blind, Placebo-Controlled Study of Intravenous Mucoid Exopolysaccharide Pseudomonas Aeruginosa Immune Globulin for Cystic Fibrosis

Bacterial Infections | Cystic Fibrosis
Agouron Pharmaceuticals

Completed

A Study of Viracept in AIDS Patients With Mycobacterium Avium Complex Disease (MAC)

HIV Infections | Mycobacterium Avium-Intracellulare Infection

United States
AJI Pharma USA

Unknown

Phase II/III Study of the Tolerance and Efficacy of Combined Use of Didanosine (2',3'-Dideoxyinosine; ddI) and Lentinan in HIV-Positive Patients

HIV Infections

United States
National Center for Research Resources (NCRR)
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Phase I/II Study of Human Anti-Cytomegalovirus (CMV) Monoclonal Antibody MSL-109 in Newborns With Symptomatic Congenital CMV Infection Without Central Nervous System Disease

Cytomegalovirus Infections
Parke-Davis

Completed

A Phase I Maximum Tolerated Dose Study of CI-1012 in Late-Stage HIV+ Patients

HIV Infections

United States
Otsuka Pharmaceutical Development & Commercialization...

Completed

Multicenter, Randomized, Double-Blind, Placebo Controlled, Efficacy Study on the Effects of Tolvaptan on Left Ventricular Dilatation in Congestive Heart Failure Patients

Congestive Heart Failure

Canada, United States
National Institute of Allergy and Infectious Diseases...

Completed

An HIV Vaccine Preparedness Study

HIV Infections

United States
Northwestern Memorial Hospital

Unknown

Study of Allogeneic Bone Marrow and T-Cell Depleted, CD34+ Peripheral Blood Stem Cell Transplantation in Patients With Aplastic Anemia

Aplastic Anemia | Graft Versus Host Disease

United States
BioCryst Pharmaceuticals

Completed

A Study of Peldesine (BCX-34) in HIV-Infected Patients

HIV Infections

United States

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