Search clinical trials for: pharmacokinetic interactions

Total 13293 results

National Institutes of Health Clinical Center (CC)

Completed

The Effect of Milk Thistle on the Pharmacokinetics of Indinavir

HIV Infection | Healthy

United States
National Institutes of Health Clinical Center (CC)

Completed

Pharmacokinetics of Mycophenolate Mofetil in Healthy Volunteers

Healthy

United States
National Institute of Neurological Disorders and...

Completed

Alpha-Galactosidase A Replacement Therapy for Fabry Disease

Fabry Disease

United States
National Cancer Institute (NCI)

Completed

A Phase I Study of Continuous Infusion Immunotoxin IgG-RFB4-SMPT-dgA in Refractory CD22 Positive B-Cell Lymphoma

B Cell Lymphoma

United States
National Institute of Dental and Craniofacial Research...

Completed

Local Flurbiprofen to Treat Pain Following Wisdom Tooth Extraction

Pain

United States
National Cancer Institute (NCI)

Completed

A Phase II Trial of 72-Hour Continuous IV Infusion of 9-Aminocamptothecin With G-CSF Support in Patients With Advanced Ovarian Cancer Previously Treated With Paclitaxel and Cisplatin

Ovarian Neoplasms

United States
National Cancer Institute (NCI)

Completed

A Phase I Trial of ZD1694 (TOMUDEX), an Inhibitor of Thymidylate Synthase, in Pediatric Patients With Advanced Neoplastic Disease

Neoplasm

United States
National Cancer Institute (NCI)

Completed

A Phase I /II Study of the Protease Inhibitor Indinavir (MK-0639) in Children With HIV Infection

HIV Infections | Acquired Immunodeficiency Syndrome

United States
National Cancer Institute (NCI)

Completed

A Phase I Study of SU101 in Pediatric Patients With Refractory Malignancy

Glioma | Sarcoma

United States
National Cancer Institute (NCI)

Completed

A Phase I Study of Oral COL-3 (NSC-683551), a Matrix Metalloproteinase Inhibitor, in Patients With Refractory Metastatic Cancer

Melanoma | Lymphoma | Renal Cell Carcinoma | Neoplasm Metastasis

United States
National Cancer Institute (NCI)

Completed

Study of Etoposide in Breast Cancer Patients

Breast Cancer

United States
National Institute of Allergy and Infectious Diseases...

Completed

Pharmacokinetics of Antiretroviral Agents in HIV-1 Infected Pregnant Women

HIV Infection

United States
National Institute of Neurological Disorders and...

Completed

1-Octanol to Treat Essential Tremor

Essential Tremor

United States
National Cancer Institute (NCI)

Completed

Phase I Study of the Safety, Tolerance, and Pharmacokinetics of FK463 in Immunocompromised Children With Fever and Neutropenia

Mycoses | Neutropenia | Fever

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Safety and Dosing Evaluation of REG1 Anticoagulation System

Healthy

United States
National Cancer Institute (NCI)

Completed

Phase II Trial of a 96-Hour Continuous Infusion of Paclitaxel Followed by Cisplatin for Patients With Stage III/IV and Relapsed NSCLC

Carcinoma, Non-Small-Cell Lung | Lung Neoplasms

United States
National Cancer Institute (NCI)

Completed

A Pharmacokinetic and Pharmacodynamic Study of Vincristine in Children With Leukemia

Leukemia | Acute Lymphocytic Leukemia

United States
National Cancer Institute (NCI)

Completed

A Pharmacokinetic Study of Genistein, a Tyrosine Kinase Inhibitor

Cancer

United States
National Cancer Institute (NCI)

Completed

Oxaliplatin in Cancer Patients With Impaired Kidney Function

Neoplasm Metastasis | Neoplasm | Kidney Disease

United States
University of Sao Paulo
Fundação de Amparo à Pesquisa do Estado de São Paulo

Completed

Propofol Pharmacokinetics and Pharmacodynamics During Cardiopulmonary Bypass

Coronary Artery Disease | Cardiopulmonary Bypass | Coronary Artery Bypass Graft

Brazil
KU Leuven
Fund for Scientific Research, Flanders, Belgium

Completed

Gene Polymorphisms in Tacrolimus Drug Interactions (DDI-TAC)

Renal Transplantation

Belgium
Novartis

Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ACZ885 in Patients With Rheumatoid Arthritis With Ongoing Treatment With Methotrexate

Rheumatoid Arthritis

Germany, Netherlands, Switzerland
Wyeth is now a wholly owned subsidiary of Pfizer

Terminated

Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SAM-315

Alzheimer Disease

France
Millennium Pharmaceuticals, Inc.

Completed

Ketoconazole Administration: How it is Affected by the Body and Broken Down and How it Acts on the Body When Used With Velcade

Tumors

United States
Makerere University
Department of Foreign Affairs, Ireland

Completed

Comparison of Plasma Drug Levels of Triomune 40 With Those of the Originator Products

HIV Infections

Uganda
University of Southern Denmark
H. Lundbeck A/S

Completed

Pupillary Changes as a Potential Biomarker for Escitalopram in Relation to CYP2C19 Polymorphism

Healthy

Denmark
Blanchette Rockefeller Neurosciences Insitute

Unknown

Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics Study of Bryostatin 1 in Patients With Alzheimer's Disease

Alzheimer's Disease

United States
BioPartners GmbH
LG Life Sciences

Completed

Sustained Release Formulation of Somatropin (rDNA Origin)for Injection

Growth Hormone Deficiency
Ludwig-Maximilians - University of Munich
University of Rochester

Completed

Effect of Hyperglycemia on Gastric Emptying Interactions With Pramlintide

Type 1 Diabetes
Javelin Pharmaceuticals

Completed

Study to Assess the Safety, Tolerability and Pharmacokinetic Profile of MNS075 (Intranasal Morphine)

Healthy

United States
Bracco Diagnostics, Inc

Completed

A Pharmacokinetics Study of MultiHance in Pediatric Patients

Central Nervous System Pathology

Poland
Javelin Pharmaceuticals

Completed

Multiple Dose Pharmacokinetics of Intranasal Ketamine

Healthy
Genaera Corporation

Completed

A Tolerance and Pharmacokinetic Study of Trodusquemine in Healthy Volunteers

Obesity

United States
National Eye Institute (NEI)

Unknown

30-Day Trial of Oral Valtrex or Valtrex Plus Aspirin on Shedding of HSV DNA in Tears and Saliva of Volunteers

Herpes Simplex

United States
Javelin Pharmaceuticals

Completed

Study to Compare the Pharmacokinetics of IV Diclofenac Sodium (2 Doses)Versus Oral Diclofenac Potassium

Healthy

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Of Pharmacokinetic (PK) Profile of Bazedoxifene (BZA) in 2 BZA/Conjugated Estrogen Forms

Postmenopause

United States
Callisto Pharmaceuticals

Completed

Safety and Efficacy of Atiprimod for Patients With Refractory Multiple Myeloma

Multiple Myeloma

United States
Avigen

Completed

Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of AV411 in Neuropathic Pain

Diabetic Neuropathy

Australia
Unither Pharmaceuticals

Terminated

A Comparative Pharmacokinetics and Safety Study of OvaRex MAb-B43.13 in Patients With Ovarian Epithelial Carcinoma

Ovarian Neoplasms

United States
University of Pittsburgh

Terminated

An Assessment of Voriconazole Pharmacokinetics and Pharmacogenetics in Liver Transplant Recipients - Pilot Study

Fungal Infection | Liver Transplant

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study To Evaluate The Pharmacokinetic Interaction Between PLA-695 And Methotrexate In Adults With Rheumatoid Arthritis

Arthritis, Rheumatoid

United States, Canada
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study of the Safety, Tolerability, Pharmacokinetics and Pharmcodynamics of ILV-094 in Healthy Subjects

Healthy

United States
University of California, Davis
U.S. Army Medical Research and Development Command

Completed

Metabolism of the Insecticide Permethrin

Pharmacokinetics | Metabolism

United States
University Hospital Tuebingen
Dr. Falk Pharma GmbH; Principal Investigator: Univ. Hosp. Tuebingen, Dept....

Completed

Pharmacokinetic Interaction Study Between Budesonide and Metronidazole in Healthy Volunteers

Healthy
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating the Safety, Pharmacokinetics, and Pharmacodynamics of SAM-531 in Healthy Young and Elderly Subjects

Alzheimer Disease

France
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SAM-531 in Healthy Subjects

Alzheimer Disease
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating the Effects of DVS SR and Paroxetine on the Pharmacokinetics of Desipramine in Healthy Subjects

Depression

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evalutating the Pharmacokinetics (PK) and Safety of a Single Dose of Desvenlafaxine Sustained Release (DVS SR)

Depressive Disorder, Major

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SAM-315 in Healthy Japanese Males

Alzheimer Disease

Japan
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Ascending Doses in Healthy

Osteoarthritis | Healthy Subjects

United States

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