Clinical Trials Sponsored by Loxbridge Research LLP

Total 1806 results

SOLTI Breast Cancer Research Group
Novartis; Alliance Foundation Trials, LLC.

Recruiting

Ribociclib vs. Palbociclib in Patients With Advanced Breast Cancer Within the HER2-Enriched Intrinsic Subtype (HARMONIA)

Metastatic Breast Cancer

United States, Spain, Portugal
Rose Research Center, LLC
Foundation for a Smoke-Free World

Recruiting

Comparative Tobacco Interventions for Individuals With Severe and Persisting Behavioral Health Disorders (THRRP)

Tobacco Use

United States
Serhat Gumrukcu, MD PhD
Frida Therapeutics LLC

Recruiting

Clinical Specimen Collection From Pompe Disease Patients

Pompe Disease

United States
Heart Rhythm Clinical and Research Solutions, LLC
Biosense Webster, Inc.

Recruiting

Real-world Experience of Catheter Ablation for the Treatment of Paroxysmal and Persistent Atrial Fibrillation (REAL-AF)

Paroxysmal Atrial Fibrillation | Persistent Atrial Fibrillation

United States
Institute of Cancer Research, United Kingdom
Merck Sharp & Dohme LLC

Recruiting

Trial of Pembrolizumab in Metastatic Castration Resistant Prostate Cancer (PERSEUS1)

Castration-resistant Prostate Cancer

United Kingdom
William Ondo, MD
Lundbeck LLC

Completed

Brain Perfusion & Oxygenation in Parkinson's Disease With NOH

Parkinson Disease | Neurogenic Orthostatic Hypotension

United States
Rose Research Center, LLC
Foundation for a Smoke-Free World

Completed

A Comparison of Exhaled Carbon Monoxide Measurements Using the iCOquit Smokerlyzer and Vitalograph Breath CO Monitor vs Carboxyhemoglobin From Venous Samples While Validating a Mobile Research Application (COCO)

Smoking, Cigarette

United States
Bharat Biotech International Limited
Georgia Institute for Clinical Research, LLC

Completed

To Determine the Safety and Efficacy of Liquid ROTAVAC 5C Vaccine Against Childhood Diarrhea Caused by Rotavirus (ROTAVAC5C)

Rotavirus Gastroenteritis
Rose Research Center, LLC
Foundation for a Smoke-Free World

Unknown

Assisting Smokers to Switch to a JUUL E-Cigarette by Devaluing Combustible Cigarettes (RECON)

Smoking Cessation | Tobacco Use Cessation | Harm Reduction | Cigarette Smoking | Tobacco Dependence | E-Cig Use

United States
DeviceFarm, Inc.
Symbio, LLC; Center for Dermatology Clinical Research, Inc.

Completed

Early Feasibility Study to Evaluate the Efficacy and Safety of the RenewalNail™ Plasma Treatment System in Patients With Mild to Moderate Onychomycosis (Fungal Nail)

Onychomycosis Due to Trichophyton Rubrum | Onychomycosis Due to Trichophyton Mentagrophytes

United States
Mani Alikhani
Propel Orthodontics, LLC

Completed

Effect of VPro5 Therapy on Clear Aligner Therapy

Malocclusion

United States
Lawrence Einhorn
Merck Sharp & Dohme LLC; Hoosier Cancer Research Network

Completed

Fosaprepitant + 5HT3 Receptor Antagonists + Dexamethasone in Germ Cell Tumors

Chemotherapy-Induced Nausea and Vomiting

United States
Centre Hospitalier Universitaire Vaudois
Agroscope Liebefeld-Posieux Research Station ALP

Completed

Effects of a Probiotics on the Health of Normal Young Males (FFF)

Inflammation | Dyslipidemia

Switzerland
McMaster University
Canadian Institutes of Health Research (CIHR); Bioventus LLC

Terminated

Randomized Trial in knEe Osteoarthritis Using Low Intensity Ultrasound - Evaluating Feasibility (RELIEF) (RELIEF)

Knee Osteoarthritis

Canada
Johnson & Johnson Pharmaceutical Research & Development...
Ortho Biotech Products, L.P.

Completed

Early and Standard Intervention With 120,000 Units of PROCRIT (Epoetin Alfa) Every Three Weeks in Patients Receiving Chemotherapy

Anemia
Johnson & Johnson Pharmaceutical Research & Development...
Ortho Biotech Products, L.P.

Completed

An Efficacy and Safety Study of PROCRIT (Epoetin Alfa) in Cancer Patients Receiving Chemotherapy Every Week or Every Four Weeks

Cancer | Anemia | Chemotherapy
Johnson & Johnson Pharmaceutical Research & Development...
Ortho Biotech Products, L.P.

Completed

An Efficacy and Safety Study of PROCRIT (Epoetin Alfa) in Cancer Patients Receiving Chemotherapy Every Three Weeks

Cancer | Anemia
Johnson & Johnson Pharmaceutical Research & Development...
Ortho Biotech Products, L.P.

Terminated

Randomized, Double-blind, Placebo-controlled Study to Assess Fatigue in Patients With ACD Due to RA Receiving PROCRIT

Rheumatoid Arthritis | Anemia
Johnson & Johnson Pharmaceutical Research & Development...
Ortho Biotech Products, L.P.

Completed

An Efficacy and Safety Study for Epoetin Alfa (PROCRIT) in Cancer Patients Not Receiving Chemotherapy or Radiation

Neoplasms | Anemia
Johnson & Johnson Pharmaceutical Research & Development...
Ortho Biotech Products, L.P.

Terminated

A Phase II Study to Assess Changes in Physical Function in Elderly Patients With Chronic Anemia

Anemia | Aged | Hemoglobins
Johnson & Johnson Pharmaceutical Research & Development...
Ortho Biotech Products, L.P.

Completed

Alternate Dosing of PROCRIT (Epoetin Alfa) in Patients With Cancer and Chemotherapy Induced Anemia

Anemia | Chemotherapy
Johnson & Johnson Pharmaceutical Research & Development...
Ortho Biotech Products, L.P.

Completed

Alternate Dosing - Initiation of Every 2 Week Epoetin Alfa (PROCRIT) in the Treatment of Anemia.

Kidney Diseases | Anemia
Johnson & Johnson Pharmaceutical Research & Development...
Ortho Biotech Products, L.P.

Terminated

A Study of PROCRIT (Epoetin Alfa) 80,000 Units (U) Once Every Four Weeks (Q4W) vs. 40,000 U Once Every Two Weeks (Q2W) in Cancer Patients Not Receiving Chemotherapy

Cancer | Anemia | Epoetin Alfa
H. Lee Moffitt Cancer Center and Research Institute
Merck Sharp & Dohme LLC; Janssen Scientific Affairs, LLC

Terminated

Ibrutinib and PD-1 Blockade in High Risk Lymphocytic Leukemia

Chronic Lymphocytic Leukemia

United States
H. Lee Moffitt Cancer Center and Research Institute
Merck Sharp & Dohme LLC; Janssen Scientific Affairs, LLC

Completed

Pembrolizumab in Combination With Ibrutinib for Advanced, Refractory Colorectal Cancers

Colorectal Cancer | Colon Cancer | Colorectal Carcinoma | Colon Disease

United States
R-Pharm Overseas, Inc.
R-Pharm; Data Management 365; Cromos Pharma LLC; Keystat, LLC; K-Research

Completed

Study to Evaluate the Effect on Parameters of Systemic Inflammation and Disease Outcomes and Safety of RPH-104 in Subjects With Acute ST-elevation Myocardial Infarction

Acute ST Segment Elevation Myocardial Infarction

United States, Russian Federation
Institute of Cancer Research, United Kingdom
Merck Sharp & Dohme LLC; Cancer Research UK; Astex Pharmaceuticals, Inc.

Recruiting

ASTEROID: A Trial of ASTX660 in Combination With Pembrolizumab (ASTEROID)

Cervical Cancer | Triple Negative Breast Cancer | Advanced Cancer

United Kingdom
Ludwig Institute for Cancer Research
Boehringer Ingelheim; MedImmune LLC; PharmaJet, Inc.; CureVac; Cancer Research Institute...

Completed

Phase 1/2 Study of Combination Immunotherapy and Messenger Ribonucleic Acid (mRNA) Vaccine in Subjects With NSCLC

NSCLC | Metastatic Non-small Cell Lung Cancer

United States
University of California, Davis
Thrasher Research Fund; California Department of Health Services; University...

Completed

Feasibility and Pilot Efficacy of Flash-heated Breast Milk to Reduce Maternal-to-Child-Transmission of HIV in Tanzania (Flash-heat)

HIV Infections

United States
Johnson & Johnson Pharmaceutical Research & Development...
Janssen, LP

Completed

Evaluation of Effectiveness and Safety of Paliperidone Extended Release in Patients With Schizoaffective Disorder.

Schizoaffective Disorder | Psychotic Disorder
Johnson & Johnson Pharmaceutical Research & Development...
Janssen, LP

Completed

Study Comparing Risperidone vs Placebo as add-on Therapy in Patients With Generalized Anxiety Disorder Who Are Sub-optimally Responding to Standard Therapy.

Anxiety Disorders
Johnson & Johnson Pharmaceutical Research & Development...
Janssen, LP

Completed

Efficacy and Safety of Two Atypical Antipsychotics vs. Placebo in Patients With an Acute Exacerbation of Either Schizophrenia or Schizoaffective Disorder

Schizophrenia | Schizoaffective Disorder

United States, India, Romania
Johnson & Johnson Pharmaceutical Research & Development...
Janssen, LP

Completed

Evaluation of Effectiveness of Risperdal® Consta® Compared to Abilify® Over a Two-year Period in Patients With Schizophrenia

Psychotic Disorders | Schizophrenia
Johnson & Johnson Pharmaceutical Research & Development...
Janssen, LP

Completed

Study Measuring Differences in Cognition Due to Sedative Effects of Risperidone and Quetiapine in Stable Bipolar I Outpatients

Bipolar Disorder
Johnson & Johnson Pharmaceutical Research & Development...
Janssen, LP

Completed

A Study of Effectiveness and Safety of Risperdal CONSTA Added to Usual Treatment in Patients With Bipolar Disorder Who Have Frequent Mood Episodes.

Bipolar Disorder
Johnson & Johnson Pharmaceutical Research & Development...
Janssen, LP

Completed

Evaluation of Effectiveness and Safety of Flexible-dose Paliperidone Extended Release in Patients With Schizoaffective Disorder.

Schizoaffective Disorder | Psychotic Disorder

United States, India, Malaysia, Romania, Korea, Republic of, Philippines
Johnson & Johnson Pharmaceutical Research & Development...
Janssen, LP

Completed

Evaluation of the Usefulness to Doctors of the Risperdal Consta Treatment Guidebook Over a Three-month Period During Which Adult Patients With Schizophrenia or Schizoaffective Disorder Are Switching From Daily Doses or Risperidone Tablets to Long-acting Risperidone by Injection

Psychotic Disorders | Schizophrenia
Johnson & Johnson Pharmaceutical Research & Development...
Janssen, LP

Completed

A Study of the Effectiveness and Safety of Risperidone to Augment SSRI Therapy in Patients With Treatment-resistant Depression

Depressive Disorder | Depression | Depressive Disorder, Major
Johnson & Johnson Pharmaceutical Research & Development...
Janssen, LP

Completed

A Study of How Long it Takes a Patient to Relapse After Switching From an Oral Antipsychotic to One of Two Doses of Long-acting Risperidone Injections in Patients With Schizophrenia or Schizoaffective Disorder

Schizophrenia | Schizoaffective Disorder
Daniela Matei, MD
Merck Sharp & Dohme LLC; Hoosier Cancer Research Network

Completed

Pembro/Carbo/Taxol in Endometrial Cancer

Endometrial Cancer | Endometrial Adenocarcinoma

United States
Johnson & Johnson Pharmaceutical Research & Development...
Janssen, LP

Completed

Study Comparing Adjunctive Risperidone Versus Placebo in Major Depressive Disorder That Is Not Responding to Standard Therapy

Major Depressive Disorder

United States
Johnson & Johnson Pharmaceutical Research & Development...
Janssen, LP

Completed

Evaluation of Effectiveness and Safety of Paliperidone ER (Extended-release) Compared With Quetiapine in Patients With Schizophrenia

Schizophrenia
Actelion
Chiltern International Ltd.; Medidata Solutions; Frontier Science & Technology... and other collaborators

Terminated

A Long Term Study to Find Out if Macitentan is an Effective and Safe Treatment for Patients With Heart Failure With Preserved Ejection Fraction and Pulmonary Vascular Disease (SERENADE OL)

Heart Failure With Preserved Ejection Fraction and Pulmonary Vascular Disease

United States, United Kingdom, Israel, Austria, Russian Federation, Germany, Poland, Denmark, Argentina, Brazil, Bulgaria, France, Hungary, Romania, Sweden
William Ondo, MD
Harmony Biosciences, LLC

Recruiting

Pitolisant in Refractory Restless Legs Syndrome

Restless Legs Syndrome

United States
MENA Center for Research & Development and Internship
Merck Sharp & Dohme LLC

Recruiting

The Epidemiology , Health and Economic Burden of RSV Amongst Hospitalized Children Under 5 Years of Age in Jordan (RSV-JO)

Respiratory Syncytial Virus Infections

Jordan
Rose Research Center, LLC
Foundation for a Smoke Free World INC

Recruiting

The Effects of Combination Zonisamide and Bupropion on Switching to an Electronic Cigarette

Smoking Cessation

United States
H. Lee Moffitt Cancer Center and Research Institute
Minneamrita Therapeutics LLC

Terminated

Dose Escalation Study of Minnelide in Relapsed or Refractory Acute Myeloid Leukemia

Acute Myeloid Leukemia

United States
Rose Research Center, LLC
Foundation for a Smoke Free World INC

Active, not recruiting

Evaluate Harm Reduction Products as a Second Line Intervention for Adult Smokers Who Do Not Quit With NRT

Smoking Cessation | Harm Reduction

United States
Food and Drug Administration (FDA)
Leiden University; Spaulding Clinical Research LLC

Completed

Effect of Selective Serotonin Reuptake Inhibitors (SSRIs) and an Opioid on Ventilation

Hypercapnia | Ventilatory Depression

United States
Nasser Hanna, M.D.
Merck Sharp & Dohme LLC; Hoosier Cancer Research Network

Completed

Consolidation Pembrolizumab Following Chemoradiation in Patients With Inoperable/Unresectable Stage III NSCLC

Carcinoma, Non-Small-Cell Lung

United States

Clinical Trials Sponsored by Loxbridge Research LLP

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