Search clinical trials for: pharmacokinetic (PK)

Total 14146 results

Genaera Corporation

Completed

A Tolerance and Pharmacokinetic Study of Trodusquemine in Healthy Volunteers

Obesity

United States
National Eye Institute (NEI)

Unknown

30-Day Trial of Oral Valtrex or Valtrex Plus Aspirin on Shedding of HSV DNA in Tears and Saliva of Volunteers

Herpes Simplex

United States
Callisto Pharmaceuticals

Completed

Safety and Efficacy of Atiprimod for Patients With Refractory Multiple Myeloma

Multiple Myeloma

United States
Avigen

Completed

Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of AV411 in Neuropathic Pain

Diabetic Neuropathy

Australia
Unither Pharmaceuticals

Terminated

A Comparative Pharmacokinetics and Safety Study of OvaRex MAb-B43.13 in Patients With Ovarian Epithelial Carcinoma

Ovarian Neoplasms

United States
University of Pittsburgh

Terminated

An Assessment of Voriconazole Pharmacokinetics and Pharmacogenetics in Liver Transplant Recipients - Pilot Study

Fungal Infection | Liver Transplant

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study To Evaluate The Pharmacokinetic Interaction Between PLA-695 And Methotrexate In Adults With Rheumatoid Arthritis

Arthritis, Rheumatoid

United States, Canada
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study of the Safety, Tolerability, Pharmacokinetics and Pharmcodynamics of ILV-094 in Healthy Subjects

Healthy

United States
University of California, Davis
U.S. Army Medical Research and Development Command

Completed

Metabolism of the Insecticide Permethrin

Pharmacokinetics | Metabolism

United States
University Hospital Tuebingen
Dr. Falk Pharma GmbH; Principal Investigator: Univ. Hosp. Tuebingen, Dept....

Completed

Pharmacokinetic Interaction Study Between Budesonide and Metronidazole in Healthy Volunteers

Healthy
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating the Safety, Pharmacokinetics, and Pharmacodynamics of SAM-531 in Healthy Young and Elderly Subjects

Alzheimer Disease

France
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SAM-531 in Healthy Subjects

Alzheimer Disease
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating the Effects of DVS SR and Paroxetine on the Pharmacokinetics of Desipramine in Healthy Subjects

Depression

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SAM-315 in Healthy Japanese Males

Alzheimer Disease

Japan
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Ascending Doses in Healthy

Osteoarthritis | Healthy Subjects

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating the Safety and Tolerability of SCA-136 in Healthy Japanese and Non-Japanese Female Subjects

Schizophrenia

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

A Study of the Safety, Tolerability, and Pharmacokinetics of AGG-523 in Healthy Japanese Males

Healthy

Japan
Shanghai Municipal Health Bureau

Unknown

Effectiveness Study on Fosinopril and/or Losartan in Patients With Chronic Kidney Disease Stage 3 (FLIP)

Proteinuria | Angiotensin II Type 1 Receptor Blockers | Chronic Kidney Insufficiency | Angiotensin-Converting Enzyme Inhibitors

China
Novartis
Hoffmann-La Roche

Completed

Safety and Pharmacokinetic Effects of Oseltamivir Alone or in Combination With Amantadine

Healthy

United States
Novartis

Completed

Single Dose Study to Assess the Safety, Tolerability, Concentration in Body and Effect of BAF312

Healthy

United States
KangLaiTe USA

Completed

Kanglaite Injection Phase I Study

Neoplasms | Solid Tumors Refractory To Standard Therapy

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating the Safety, Pharmacokinetics, and Pharmacodynamics of MYO-029

Healthy
Keio University

Terminated

Safety and Efficacy Study of Salvage Chemotherapy (R-ESHAP) to Treat Relapsed and Refractory Aggressive Non-Hodgkin's Lymphoma

Lymphoma, Non-Hodgkin

Japan
GP-Pharm

Completed

Leuprolide Acetate 3.75 mg Depot to Treat Prostate Cancer

Prostate Cancer

United States, Austria, Czech Republic, Germany, Hungary, Italy, Slovakia, Spain, United Kingdom
Abbott

Withdrawn

A Dose-Finding Study to Evaluate the Safety, Efficacy and Pharmacokinetics of Adalimumab in Subjects With Refractory Asthma

Asthma
Charite University, Berlin, Germany
Novartis

Completed

Pharmacokinetics of Everolimus and Enteric-Coated Mycophenolatesodium Before and After Withdrawal of Cyclosporine in Renal Transplant Patients

Renal Transplantation

Germany
University Hospital, Limoges
Hoffmann-La Roche

Completed

Study of the Pharmacokinetic Action of Amantadine and Ribavirin in Chronic Hepatitis C. CINAM (CINAM)

Chronic Hepatitis C

France
Northwell Health
The Cleveland Clinic; University of North Carolina

Completed

Pilot Studies of Novel Therapies to Treat Resistant Focal Segmental Glomerulosclerosis (FSGS)

Focal Glomerulosclerosis

United States
HiberCell, Inc.

Completed

Phase Ia Dose-Escalation Safety, Pharmacodynamic and Pharmacokinetic Study of Imprime PGG™ Injection

Healthy
HiberCell, Inc.

Completed

Multiple-Dose, Dose-Escalation Safety, Pharmacodynamics, and Pharmacokinetics Study of Imprime PGG™ Injection

Healthy
King Saud University

Completed

Evaluating Pharmacokinetics and Pharmacodynamics of Jusline

Healthy

Saudi Arabia
Rottapharm Spain

Completed

Study of the Modification of the Pharmacokinetic Profile of Levodopa by the Fiber Plantago Ovata Husk

Parkinson's Disease, Idiopathic

Spain
National Cancer Center, Korea

Unknown

Study of Genetic Polymorphisms of Drug Transporters and Orphan Nuclear Receptors on Treatment Effects of Irinotecan

Colorectal Neoplasms | Secondary

Korea, Republic of
Eunice Kennedy Shriver National Institute of Child...
Sanofi-Synthelabo

Completed

Single Dose Pharmacokinetic and Pharmacodynamic Evaluation of Three Different Doses of Zolpidem in Children

Sleep Disorder | Insomnia

United States
University of Oslo School of Pharmacy

Terminated

Ganciclovir Pharmacokinetics in Patients Undergoing Continuous Renal Replacement Therapy

Acute Renal Failure | Cytomegalovirus Infections | Multi Organ Failure

Norway
Eunice Kennedy Shriver National Institute of Child...

Unknown

A Pharmacokinetic Study of Actinomycin-D and Vincristine in Children With Cancer

Cancer

United States
Novartis

Completed

Safety, Tolerability, Effect of Vildagliptin and How the Body Changes the Blood Level of Vildagliptin in Healthy Chinese Volunteers

Healthy

China
Novartis
Schering-Plough

Completed

Study of Mometasone Furoate/Formoterol Fumarate Inhalation Combination in Healthy Volunteers

Healthy

United Kingdom
Novartis

Completed

Drug Interaction of SMC021 With Concomitant Antacid (Calcium Carbonate/Magnesium Hydroxide).

Health Postmenopausal Women

Denmark
Novartis

Completed

Effect of Moderate Hepatic Impairment on the Pharmacokinetics and Metabolism of a Single Dose of Licarbazepine

Healthy

Czech Republic
Novartis

Completed

Safety and Tolerability of AQW051 in Elderly Healthy Volunteers.

Healthy

United Kingdom
Novartis

Completed

Effect of Food on the Pharmacokinetics of AQW051 in Japanese Healthy Male Subjects

Healthy

Japan
Novartis

Completed

Effect of Severe Renal Impairment on Pharmacokinetics and Metabolism of a Single Administration of Licarbazepine

Healthy

Czech Republic
Novartis

Completed

Study to Explore the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Oral AHT956 in Healthy Subjects

Healthy

Switzerland
SK Chemicals Co., Ltd.

Completed

Phase I Study to Investigate the Alcohol Interaction of SK3530

Erectile Dysfunction

Korea, Republic of
Novartis

Completed

Evaluation of Pharmacokinetic Interaction of Indacaterol With Ketoconazole in Healthy Adult Subjects

Healthy

India
Nordic Bioscience A/S
Novartis

Completed

Pharmacokinetics/Pharmacodynamics of Oral Salmon Calcitonin in Patients With Osteoarthritis

Osteoarthritis

Denmark
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating the Effects of DVS SR and Duloxetine on the Pharmacokinetics of Desipramine in Healthy Subjects

Depressive Disorder | Depression | Depressive Disorder, Major

United States
Novartis

Completed

Effects of Water and Food Intake on the Pharmacokinetics and Pharmacodynamics of Oral Salmon Calcitonin in Healthy Postmenopausal Women

Postmenopausal Osteoporosis

Denmark
RFS Pharma, LLC

Completed

Safety, Tolerance, Pharmacokinetic and Antiviral Study of Amdoxovir in Combination With Zidovudine in Adults With HIV

HIV Infections

Argentina

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