Search clinical trials for: Controlled Human Exposure Study

Total 145176 results

Pfizer

Completed

Six Month Clinical Trial Assessing Efficacy and Safety of Inhaled Insulin in Type 1 Diabetes

Diabetes Mellitus, Type 1

United States, Canada
Heidelberg University
Dietmar Hopp Stiftung; Prof. Wolfgang Stremmel

Completed

Dose Finding Study for Retarded Phosphatidylcholine in Pancolitis

Ulcerative Colitis

Germany
Abant Izzet Baysal University

Unknown

A Study Evaluating the Effects of Lipid Lowering Treatment on Steroid Synthesis

Diabetes Mellitus | Hypercholesterolemia | Coronary Heart Disease | Non-Coronary Atherosclerotic Disease

Turkey
University of Calgary
Canadian Institutes of Health Research (CIHR); LEO Pharma; Dupont Applied Biosciences

Completed

Trial of the Effect of Low-Molecular-Weight Heparin (LMWH) Versus Warfarin on Mortality in the Long-Term Treatment of Proximal Deep Vein Thrombosis (DVT) (Main LITE Study)

Thrombosis | Venous Thrombosis | Thromboembolism

Canada
Abbott

Completed

The Safety and Efficacy of Divalproex Sodium Extended-Release Tablets in Migraine Prophylaxis: A Study in Adolescents

Migraine

United States
Assistance Publique - Hôpitaux de Paris

Terminated

Influenza Vaccination of Nursing Home Workers.

Influenza Disease

France
Critical Therapeutics

Unknown

Study of Oral Zileuton in the Treatment of Moderate to Severe Facial Acne Vulgaris

Acne Vulgaris

United States
Ilypsa

Unknown

Efficacy and Tolerability of ILY101 in Dialysis Patients With Hyperphosphatemia

Kidney Diseases | Renal Insufficiency

United States
Medical University of Vienna

Completed

Retinal Oxygen Reactivity in Patients Infected With Human Immunodeficiency Virus (HIV)

HIV Infections | Ocular Physiology | Retina

Austria
Postgraduate Institute of Medical Education and...

Unknown

A Comparative Study of the Safety and Efficacy of Face Talc Slurry and Iodopovidone for Pleurodesis

Primary Spontaneous Pneumothorax | Malignant Pleural Effusions | Recurrent Pleural Effusions | Secondary Spontaneous Pneumothorax

India
Odense University Hospital

Completed

OXY-2: The Pharmacogenetics of Oxycodone Analgesia in Human Experimental Pain Models

Healthy

Denmark
Royal Brompton & Harefield NHS Foundation Trust

Completed

Oral Allergy Syndrome (OAS): a Pilot Study to Evaluate a Clinical Questionnaire as a Diagnostic Tool

Rhinitis | Food Allergy

United Kingdom
PowderMed

Completed

Safety Study of HSV2 DNA Vaccine to Treat Patients With Recurrent Genital Herpes Caused by HSV-2

HSV-2

United States
University of Oxford

Completed

A Phase I Study of the Safety and Immunogenicity of a Recombinant MVA Vaccine Encoding a Secreted Antigen From M. Tuberculosis, Antigen 85A, Delivered Intradermally by a Needle Injection in Healthy Volunteers Who Have Previously Received BCG

Tuberculosis

United Kingdom
University of Oxford
Merck KGaA, Darmstadt, Germany

Unknown

Oxford Niaspan Study: Effects of Niaspan on Atherosclerosis and Endothelial Function

Atherosclerosis

United Kingdom
University of Oxford

Completed

A Phase I Study of the Safety and Immunogenicity of a Recombinant MVA Vaccine Encoding a Secreted Antigen From M. Tuberculosis, Antigen 85A, Delivered Intradermally by a Needle Injection in Healthy Volunteers Who Have Received BCG Immunisation 1 Month Previously

Tuberculosis

United Kingdom
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating Sirolimus and Cyclosporine in Kidney Transplant Recipients

Renal Transplantation
Eli Lilly and Company

Completed

Bipolar Depression Study: Bipolar Depression Assessment Study on Treatment Response

Depression, Bipolar

United States, Puerto Rico
Eli Lilly and Company

Completed

An Open-Label Study of Atomoxetine in Adolescents With Attention-Deficit/Hyperactivity Disorder

Attention Deficit Hyperactivity Disorder

Germany
Memorial Sloan Kettering Cancer Center

Completed

A Randomized Study of the Efficacy of Low Venous Pressure General Anesthesia Versus Combined Spinal-Epidural Anesthesia in Decreasing Blood Loss During Prostate Surgery

Prostate Cancer

United States
Eli Lilly and Company

Completed

An Open-Label Study of Atomoxetine in Children With Attention-Deficit/Hyperactivity Disorder

Attention Deficit Hyperactivity Disorder

Germany
Otsuka Pharmaceutical Development & Commercialization...
Otsuka Pharmaceutical Co., Ltd.

Completed

"SALT Trial" Study of Ascending Levels of Tolvaptan in Hyponatremia

Inappropriate ADH Syndrome | Water Intoxication | Hyponatremias | Water-Electrolyte Imbalances

United States
Eli Lilly and Company

Completed

A Study of LY317615 in Patients With Brain Tumors

Malignant Glioma

United States
Eli Lilly and Company

Completed

A Study of Biweekly Pemetrexed and Gemcitabine in Patients With Metastatic Breast Cancer

Breast Cancer

Canada
Eli Lilly and Company

Completed

Phase 2 Study on Use of a Combination of Pemetrexed in Patients With Advanced Gastric Carcinoma

Gastrointestinal Neoplasms

Korea, Republic of
Eli Lilly and Company

Completed

A Study of Pemetrexed in Small Cell Lung Cancer, Which Has Returned

Carcinoma, Small Cell

United States
Eli Lilly and Company

Completed

A Study of Pemetrexed Plus Oxaliplatin as First Line Therapy in Advanced Gastric Carcinoma

Advanced Gastric Carcinoma

Italy
Eli Lilly and Company

Completed

A Study Comparing Pemetrexed Plus Best Supportive Care Versus Best Supportive Care Alone in the Treatment of Mesothelioma

Mesothelioma

Canada
Eli Lilly and Company

Completed

A Single Arm Phase 2 Study of Pemetrexed as 2nd-Line Treatment of Advanced Non-Small Cell Lung Cancer

Carcinoma, Non-Small Cell Lung

China, Taiwan, Australia, Korea, Republic of, Egypt, Romania, India, Turkey
Eli Lilly and Company

Completed

Study Comparing Short Infusion Vs. Fixed Dose of Cisplatin + Gemcitabine in Non Small Cell Lung Cancer.

Non-Small-Cell Lung Carcinoma

Argentina, Brazil, Chile, Mexico
Retinal Consultants Medical Group

Completed

Combination Bevacizumab and Verteporfin (Two Different Sequences of Treatment)in Neovascular AMD

Macular Degeneration | Choroidal Neovascularization

United States
Eli Lilly and Company
Boehringer Ingelheim

Completed

A Randomized Double Blind Study Evaluating Duloxetine in Outpatients With MDD and Pain

Depressive Disorder, Major

Belgium, Germany, France, Slovakia, Czech Republic, Finland
Eli Lilly and Company

Completed

A Study With LY293111, Gemcitabine and Placebo in Patients With Pancreatic Cancer

Pancreatic Cancer

United States
Eli Lilly and Company

Completed

A Study in People With Abnormal Fat Levels in the Blood

Dyslipidemia

United States
Eli Lilly and Company
Boehringer Ingelheim

Completed

Open Label Phase III Duloxetine Study for Stress Urinary Incontinence

Urinary Incontinence Stress

United Kingdom
Eli Lilly and Company
Aventis Pharmaceuticals

Completed

A Randomized Study Evaluating the Feasibility and Activity of Three Different Combination With Gemcitabine as First Line Therapy for Non Small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung

Italy
Eli Lilly and Company

Completed

A Study on Induced Weight Gain During Atypical Antipsychotic Treatment and Its Management With Psychoeducational Programme

Weight Gain

Italy
Eli Lilly and Company

Completed

Efficacy Study of LY2422347 to Treat Insomnia

Sleep Initiation and Maintenance Disorders

United States
Eli Lilly and Company

Completed

Study of Atomoxetine in Children With ADHD to Assess Symptomatic and Functional Outcomes

Attention-Deficit/Hyperactivity Disorder

Canada
QDose Limited

Unknown

Investigating the Pharmacokinetics and Pharmacodynamics of Recombinant Human Insulin Administered by Dry Powder Inhaler

Diabetes Mellitus

United States
Geha Mental Health Center

Unknown

Reboxetine Treatment in Depressed Children and Adolescents an 8-Week, Open Study

Depression

Israel
BZL Biologics

Completed

Phase II Trial of Monoclonal Antibody (J591) in Combination With Low-Dose Subcutaneous Interleukin-2

Prostatic Neoplasms

United States
Charite University, Berlin, Germany

Terminated

Pilot-Study of Thalidomide in Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis (ALS)

Germany
University Hospitals, Leicester

Unknown

A Study of the Effects of Sodium Citrate on Olfactory Thresholds

Anosmic and Hyposmic Patients
University of Oxford

Completed

A Phase I Study of the Safety and Immunogenicity of a Recombinant MVA Vaccine Encoding a Secreted Antigen From M. Tuberculosis, Antigen 85A, Delivered Intradermally by a Needle Injection in Healthy Volunteers.

Tuberculosis

United Kingdom
Japan Clinical Oncology Group
Ministry of Health, Labour and Welfare, Japan

Terminated

Study of Standard CHOP Versus Biweekly CHOP in Aggressive Non-Hodgkin's Lymphoma (JCOG9809)

Non-Hodgkin's Lymphoma

Japan
Pfizer

Terminated

Open Label Sumanirole Study of Safety, Tolerability, and Therapeutic Response In Patients With Parkinson's Disease

Parkinson Disease

Colombia, United States, Argentina, Puerto Rico
Gilead Sciences

Completed

A Clinical Study to Evaluate the Effects of Darusentan on Safety and Efficacy in Subjects With Resistant Systolic Hypertension Receiving Combination Therapy With Three or More Blood Pressure Lowering Drugs

Hypertension
University of Oxford

Completed

A Phase I Study of the Safety and Immunogenicity of MVA85A in Healthy Gambian Volunteers

Tuberculosis

Gambia
University of Aarhus
The Swedish Research Council for Environment, Agricultural Sciences and Spatial...

Completed

SENOC-I Det Sunda Huset II - Sensitization of Occupants of Water Damaged Buildings.

Upper Airway, Irritation Inflammation, Discomfort

Denmark

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