Search clinical trials for: 0.9% NaCl solution

Total 23210 results

Karolinska Institutet
Danderyd Hospital

Completed

Endotoxin-induced Inflammatory and Behavioral Responses and Predictors of Individual Differences

Sickness Behavior
Santen Inc.

Completed

Study Assessing the Efficacy and Safety of STN1013600 Ophthalmic Solution 0.1% and 0.3% Compared With Placebo in Subjects With Presbyopia (OPSIS)

Presbyopia

United States
Microgen

Recruiting

Clinical Study in the Treatment of Patients With Moderate Course of COVID-19

COVID-19

Russian Federation
Niels Van Regenmortel

Completed

TOnicity of Perioperative Maintenance SoluTions (TOPMAST-1)

Water-Electrolyte Imbalance | Fluid Overload | Thoracic Diseases | Fluid Retention | Sodium Disorder | Potassium Disorders | Chloride Disorder

Belgium
University Hospital, Antwerp
Baxter Healthcare Corporation

Completed

Metabolism of Isotonic Versus Hypotonic Maintenance Solutions in Fasting Healthy Adults (MIHMoSA)

Healthy Adult Volunteers

Belgium
Nuvo Research GmbH

Completed

PILOT STUDY OF THE EFFICACY AND SAFETY OF WF10 IN SUBJECTS SUFFERING FROM PERSISTENT ALLERGIC RHINITIS

Allergic Rhinitis

Germany
Rigel Pharmaceuticals

Completed

Safety and Efficacy Study of R932348 Ophthalmic Solution in Chronic Ocular Graft Versus Host Disease Patients(DROPS-2) (DROPS-2)

Chronic Graft-versus-host Disease

United States
Alnylam Pharmaceuticals

Completed

APOLLO: The Study of an Investigational Drug, Patisiran (ALN-TTR02), for the Treatment of Transthyretin (TTR)-Mediated Amyloidosis

Amyloid Neuropathies | Amyloid Neuropathies, Familial | TTR-mediated Amyloidosis | Amyloidosis, Hereditary | Amyloidosis, Hereditary, Transthyretin-Related | Familial Amyloid Polyneuropathies

United States, Canada, Argentina, Australia, Bulgaria, Cyprus, Italy, Japan, Malaysia, Mexico, Netherlands, Portugal, Spain, Sweden, Germany, France, Brazil, Turkey, Korea, Republic of, Taiwan, United Kingdom
Alnylam Pharmaceuticals

Completed

A Phase 1, Single- and Multi-Dose, Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Subcutaneously Administered ALN-TTRSC (Revusiran) in Healthy Volunteers

TTR-mediated Amyloidosis

United Kingdom
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...

Unknown

Effects of Different Crystalloid Solutions for Extra-corporeal Membrane Oxygenator (ECMO) Priming

Acute Respiratory Failure

Italy
Alcon Research

Completed

Clinical Outcomes Following Treatment With Systane® Balance in Dry Eye Subjects

Dry Eye
Rigel Pharmaceuticals

Completed

To Assess the Safety and Efficacy of R932348 Ophthalmic Solutions in Patients With Keratoconjunctivitis Sicca (DROPS)

Keratoconjunctivitis Sicca

United States
University of Iowa

Completed

Essential Fatty Acids for Major Depression

Major Depression

United States
Innovaderm Research Inc.

Completed

Effect of RANKL Inhibition on UV-induced Immunosuppression

Hypersensitivity, Delayed | Immunosuppression | Ultraviolet Rays | Immune Tolerance/Drug Effects

Canada
MassBiologics
Celerion

Completed

First Clinical Study of the Safety and Blood Levels of a Human Monoclonal Antibody (2217LS) Against Lyme Disease Bacteria in Healthy People

Lyme Disease

United States
Ionis Pharmaceuticals, Inc.
Akcea Therapeutics

Completed

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of IONIS APO(a)-LRx in Healthy Volunteers With Elevated Lipoprotein(a)

Elevated Lipoprotein(a)

Canada
Alnylam Pharmaceuticals

Active, not recruiting

HELIOS-B: A Study to Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

Transthyretin Amyloidosis (ATTR) With Cardiomyopathy

United States, Poland, Argentina, Australia, Belgium, France, Germany, Japan, Netherlands, Portugal, Spain, Sweden, United Kingdom, Canada, Czechia, Denmark, Hungary, Ireland, Norway, Korea, Republic of, Austria, Croatia, Israel, Latvia, Lithuan... and more
Universitas Bali Internasional

Completed

The Effects of Intra-articular Platelet-Rich Plasma Injection on The Severity of Knee Osteoarthritis

Osteoarthritis, Knee

Indonesia
Assistance Publique - Hôpitaux de Paris

Completed

Cell Therapy Using Umbilical Cord-derived Mesenchymal Stromal Cells in SARS-CoV-2-related ARDS (STROMA-CoV2)

Severe Acute Respiratory Syndrome Coronavirus 2 | Severe Acute Respiratory Distress Syndrome

France
Arrowhead Pharmaceuticals

Completed

Study of ARO-HSD in Healthy Volunteers and Patients With Non-Alcoholic Steatohepatitis (NASH) or Suspected NASH

Non-alcoholic Steatohepatitis

New Zealand
Dicerna Pharmaceuticals, Inc.

Completed

Study to Evaluate Safety, Tolerability, PK and PD of DCR-PHXC in PH Type 3 Patients (PHYOX4)

Primary Hyperoxaluria Type 3

United States, Germany, Netherlands, United Kingdom
Arrowhead Pharmaceuticals

Completed

Study of ARO-HBV in Normal Adult Volunteers and Patients With Hepatitis B Virus (HBV)

Hepatitis B

Australia, Hong Kong, New Zealand
Berlin Cures GmbH

Completed

A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Efficacy of BC 007 in Healthy Subjects

Healthy Volunteers

Germany
Alnylam Pharmaceuticals

Completed

A Study of the Safety, Tolerability and Pharmacokinetics of ALN-TTR02 in Japanese Healthy Volunteers

Transthyretin (TTR)-Mediated Amyloidosis

United Kingdom
LipimetiX Development, LLC

Completed

Safety Study of AEM-28 to Treat Refractory Hypercholesterolemia

Hypercholesterolemia | Hyperlipoproteinemia Type II

Australia
Rigshospitalet, Denmark

Completed

Acute Exercise and NK Cell Regulation in Tissue and Circulation After IL-6R Blockade

Appetitive Behavior | Physical Stress | Interleukin-6 Inhibition

Denmark
Preben Kjolhede, MD, professor

Completed

Tranexamic Acid in Surgery of Advanced Ovarian Cancer

Ovarian Cancer

Sweden
Thomas Jefferson University

Unknown

The Use of a Restrictive Fluid Regimen With Hypertonic Saline for Patients Undergoing Pancreaticoduodenectomy

Pancreaticoduodenectomy

United States
University of Oxford
NIHR Oxford Health Biomedical Research Centre

Not yet recruiting

Semaglutide and Cognition in Healthy Volunteers (OxSENSE)

Cognitive Change

United Kingdom
Rigel Pharmaceuticals

Completed

A Safety, Tolerability and Pharmacokinetics Study of R932348 Eye Drops in Patients With Dry Eye Disease

Keratoconjunctivitis Sicca

United States
Heinrich-Heine University, Duesseldorf
CSL Behring

Withdrawn

Haemate HS in Patients With Severe Bleeding Undergoing Valve Replacement Due to Aortic Stenosis (HAVAS)

Blood Loss, Surgical

Germany
University Hospital, Ghent

Withdrawn

Diagnosis of Urethral Stricture With Sono-urethrography vs Conventional Urethrography (SONO-URETHRA) (SONO-URETHRA)

Urethral Stricture Disease

Belgium
University of Liege

Completed

G-CSF in the Treatment of Toxic Epidermal Necrolysis (NeupoNET)

Stevens - Johnson Syndrome

Belgium
University Hospital, Basel, Switzerland
Swiss National Science Foundation

Completed

PROVOCATION Trial - PROphylactic intraVenOus Hydration for Contrast Agent Toxicity PreventION

Kidney Failure, Acute

Switzerland, Italy
PhaseBio Pharmaceuticals Inc.

Completed

Phase 1/2a, Randomized, Double-Blind, Placebo-Controlled, Study to Assess Safety, Tolerability, PK and PD Response of PB1023 Injection Following Single and Multiple SQ Doses in Adults With Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

United States
University Hospital, Grenoble

Completed

Early Administration of Prothrombin Concentrate Complex in Patients With Acute Hemorrhage Following Severe Trauma (PROCOAG)

Shock, Hemorrhagic

France
Suez Canal University

Unknown

Effect of Glucose 5% on Labor Length

Induction of Labor Affected Fetus / Newborn

Egypt
University of North Carolina, Chapel Hill
United States Department of Defense; RTI International; Environmental Protection...

Completed

Effects of 20,000 EU of Clinical Center Reference Endotoxin (CCRE) Versus Placebo(ENDOHEART) (Endoheart)

Healthy

United States
Egetis Therapeutics

Completed

Mangafodipir as an Adjunct to FOLFOX6 Chemotherapy in Colon Cancer Stage Dukes' C (MANFOL)

Chemotherapy | Colon Cancer

Sweden
Assistance Publique - Hôpitaux de Paris

Completed

Ilomedin in Septic Shock With Persistent Microperfusion Defects (I-MICRO) (I-MICRO)

Septic Shock Hyperdynamic

France
Rawalpindi Medical College

Completed

Effect of Hot Saline Irrigation on the Operative Field During Endoscopic Sinus Surgery

Rhinosinusitis

Pakistan
MassBiologics

Completed

Evaluate the Safety Pharmacokinetics of a Human Monoclonal Antibody S315 Against Diphtheria Toxin in Healthy Subjects (S315)

Diphtheria

United States
Virginia Commonwealth University

Withdrawn

Ideal Initial Bolus and Infusion Rate for Erector Spinae Plane Block Catheters

Pain, Postoperative | Pain, Chest

United States
Ostergotland County Council, Sweden
Linkoeping University

Completed

Effects of Seminal Plasma on Pregnancy Rate With IVF (SENAVA)

Infertility

Sweden
Beth Israel Deaconess Medical Center

Recruiting

Corticosteroids to Treat Pancreatitis (CRISP)

Pancreatitis | Pancreatitis, Acute | Corticosteroid | Hydrocortisone

United States
Haukeland University Hospital

Completed

Fluid Shifts in Patients Treated With Therapeutic Hypothermia After Cardiac Arrest

Cardiac Arrest

Norway
Medical University of Vienna

Completed

Changes in Adaptive Immune Responses and Effector Cell Responses Upon Nasal Allergen Exposure - a Pilot Study

Allergic Rhinitis | Allergic Inflammation

Austria
Alcon Research

Completed

The Effect of SYSTANE® BALANCE on Tear Film Break Up Time in Dry Eye Subjects

Dry Eye

Argentina
University Hospital, Basel, Switzerland

Completed

Study of Postoperative ICC Analgesia (SPICA)

Postoperative Analgesia

Switzerland
The Hospital for Sick Children

Completed

0.9% NaCl/Dextrose 5% vs 0.45% NaCl/Dextrose 5% as Maintenance Intravenous Fluids in Hospitalized Children

Hyponatremia

Canada

Search clinical trials for: 0.9% NaCl solution

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