Search clinical trials for: AMG 510

Total 5426 results

Amgen

Completed

Study to Evaluate the Safety, Tolerability and Pharmacokinetics of AMG 986 Administered Orally to Healthy Volunteers and Participants With Severely Impaired Renal Function

Heart Failure

United States
Amgen

Available

AMG 701 Expanded Access Program
Amgen

Completed

A Phase 1/2 Study Evaluating AMG 337 in Asian Subjects

Stomach Neoplasms

Japan
AstraZeneca

Completed

Multiple Ascending Doses of AMG 139 in Healthy and Crohn's Disease Subjects

Crohn's Disease

United States, Australia
Amgen

Terminated

Multiple Ascending Dose Study in Subjects With Type 2 Diabetes

Diabetes Mellitus

United States
Amgen

Completed

Safety Study of AMG 811 in Subjects With Systemic Lupus Erythematosus With and Without Glomerulonephritis

Systemic Lupus Erythematosus | Nephritis

United States, Hong Kong, France, Malaysia, Mexico
Amgen

Terminated

Single Ascending Dose Trial in Patients With Type 2 Diabetes

Diabetes Mellitus

United States
Amgen

Terminated

A Study of AMG 114 Administered by Subcutaneous Injection for the Treatment of Anemia in Subjects With Non-Myeloid Malignancies Receiving Multicycle Chemotherapy

Cancer | Anemia
Amgen

Completed

A Study to Evaluate the Impact of Omeprazole on the Pharmacokinetics of Sotorasib Co-administered With an Acidic Beverage in Healthy Volunteers

Healthy Volunteers

United States
Kafrelsheikh University

Completed

Ridge Augmentation With Simultaneous Implant Placement Using Bone Blocks With Autogenous Tooth Graft

Implant | Ridge Augmentation | Autogenous Tooth Graft

Egypt
Beijing VDJBio Co., LTD.

Completed

Clinical Study of Single Dose IL-6R mAb Injection in RA Patients

Rheumatoid Arthritis

China
Chong Kun Dang Pharmaceutical

Completed

A Study to Evaluate the Relative Bioavailability of Formulations of CKD-510 and to Assess the Effect of Food on the CKD-510 Tablet Formulation in Healthy Subjects

Healthy Volunteers

United States
Hansoh BioMedical R&D Company

Recruiting

A Study to Evaluate Efficacy and Safety of HS-10374 for Moderate to Severe Plaque Psoriasis

Psoriasis

China
Shanghai Henlius Biotech

Active, not recruiting

A Clinical Study Evaluating the Use of HLX10 in Combination With HLX04 for the Treatment of Advanced Hepatocellular Carcinoma (HCC) Patients

Hepatocellular Carcinoma

China
Korea University Anam Hospital

Completed

Effect of Low-dose vs. High-dose Pitavastatin on In-stent Restenosis (ELEVATE)

Atherosclerosis | Neointima | Angina

Korea, Republic of
Amgen

Completed

Single and Multiple Ascending Dose Study of AMG 133 in Participants With Obesity

Obesity

United States
Amgen

Terminated

Single and Multiple Ascending Dose Study of AMG 171 in Subjects With Obesity

Obesity

United States
Amgen

Completed

A Study to Evaluate the Safety, Tolerability, Immunogenicity, Pharmacokinetics, and Pharmacodynamics of AMG 592 in Healthy Participants

Chronic Graft-versus-host Disease (cGVHD)

United States
Amgen

Completed

P3 Study to Evaluate Efficacy and Safety of AMG 531 in Thrombocytopenic Japanese Subjects With Immune (Idiopathic) Thrombocytopenic Purpura

Idiopathic Thrombocytopenic Purpura
Amgen

Completed

AMG 529 First in Human Study

Cardiovascular

United States
Dana-Farber Cancer Institute
Massachusetts General Hospital; Brigham and Women's Hospital; Amgen; H. Lee Moffitt...

Completed

AMG 479 in Advanced Carcinoid and Pancreatic Neuroendocrine Tumors

Neuroendocrine Tumor | Carcinoid Tumor | Pancreatic Neuroendocrine Tumor

United States
Amgen

Completed

Study to Assess Fixed Dosing of AMG 223 in Subjects With Chronic Kidney Disease on Hemodialysis With Hyperphosphatemia

End Stage Renal Disease | Chronic Kidney Disease | Kidney Disease | Hyperphosphatemic
Amgen

Completed

Safety, Tolerability, and Pharcodynamics of AMG 853 in Adolescents With Asthma

Asthma
Amgen

Completed

A First-in-human Study Evaluating AMG 167 in Healthy Men and Postmenopausal Women

Osteopenia
Amgen

Not yet recruiting

A Study of AMG 732 in Healthy Participants and Participants With Thyroid Eye Disease

Thyroid Eye Disease
Amgen

Active, not recruiting

Dose-ranging Study to Evaluate the Efficacy, Safety, and Tolerability of AMG 133 in Adult Subjects With Overweight or Obesity, With or Without Type 2 Diabetes Mellitus

Obesity | Overweight | Type 2 Diabetes Mellitus

United States, Czechia, Taiwan, Canada, Japan, Korea, Republic of, Germany, Hungary, Australia, Hong Kong, Spain, Poland
Amgen

Completed

A Study to Evaluate the Pharmacokinetics, Safety, and Pharmacodynamics of Olpasiran in Participants With Normal Renal Function and Participants With Various Degrees of Renal Impairment

Renal Impairment

United States
Amgen

Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of AMG 890 in Subjects With Elevated Plasma Lipoprotein(a)

Cardiovascular Disease

United States, Australia
Amgen

Completed

Study to Evaluate the Efficacy and Safety of AMG 301 in Migraine Prevention

Chronic Migraine or Episodic Migraine

United States, Germany, Austria, Czechia, Canada, Denmark, Finland, Sweden
Kyowa Kirin Co., Ltd.

Completed

Open Label Extension Study of AMG 531 in Japanese Subjects With ITP

Immune (Idiopathic) Thrombocytopenic Purpura (ITP)

Japan
Jonsson Comprehensive Cancer Center
NantCell, Inc.

No longer available

Single Patient Expanded Access to Ganitumab for Metastatic Ewing Sarcoma

Ewing Sarcoma
Amgen

Completed

AMG 853 Phase 2 Study in Subjects With Inadequately Controlled Asthma

Asthma
Amgen

Completed

A Study to Examine the Safety, Pharmacokinetics and Pharmacodynamics of AMG 623 in Subjects With Systemic Lupus Erythematosus

Systemic Lupus Erythematosus
Amgen

Terminated

Phase I, Double-Blind,Placebo, MAD Study to Evaluate the Safety, Tolerability, PK, and PD of AMG 333 in Healthy Subjects and Migraine Subjects

Migraine

United States
Amgen

Completed

A Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of AMG 557 in Subjects With Systemic Lupus Erythematosus

Systemic Lupus Erythematosus

United States, United Kingdom
Amgen

Completed

Single-Ascending Dose Study of AMG 333 in Healthy Subjects and Subjects With Migraines

Migraine

United States
Amgen

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AMG 811 in Subjects With Systemic Lupus Erythematosus

Systemic Lupus Erythematosus
Kyowa Kirin Co., Ltd.

Completed

Safety Study of AMG 531 in Japanese Subjects With ITP

Thrombocytopenia in Subjects With Immune (Idiopathic) Thrombocytopenic Purpura (ITP)
Amgen

Terminated

First-in-Human Study to Evaluate AMG 579 in Healthy Subjects and Patients With Stable Schizophrenia

Schizophrenia

United States
Amgen

Recruiting

A Phase 1/2 Study of AMG 193 in Combination With IDE397 in Participants With Advanced Methylthioadenosine Phosphorylase (MTAP)-Null Solid Tumors

MTAP-null Non-Small-Cell Lung Cancer | MTAP-null Solid Tumors

United States, Australia
Amgen

Recruiting

Single and Multiple Ascending Dose Study to Evaluate AMG 786 in Healthy Participants and Participants With Obesity

Obesity

United States
Amgen

Completed

A Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Olpasiran in Chinese Participants With Elevated Serum Lipoprotein(a)

Elevated Serum Lipoprotein(a)

Hong Kong
Amgen

Completed

A Study to Evaluate the Pharmacokinetics, Safety, and Pharmacodynamics of Olpasiran in Participants With Various Degrees of Hepatic Impairment

Hepatic Impairment

United States
Amgen

Terminated

Study of Emerfetamab (AMG 673) in Adults With Relapsed/Refractory Acute Myeloid Leukemia (AML)

Acute Myeloid Leukemia

United States, Australia, Germany
Amgen

Completed

A Study to Evaluate the Pharmacokinetics, Safety and Tolerability of AMG 592 in Healthy Japanese Participants

Chronic Graft-versus-Host Disease (cGVHD)

Australia
Amgen

Completed

AMG 531 Treatment of Thrombocytopenic Subjects With Immune (Idiopathic) Thrombocytopenic Purpura (ITP) Prior to Splenectomy

Thrombocytopenia | Idiopathic Thrombocytopenic Purpura
Amgen

Completed

AMG 531 Treatment of Thrombocytopenic Subjects With Immune (Idiopathic) Thrombocytopenic Purpura (ITP) Refractory to Splenectomy

Thrombocytopenia | Idiopathic Thrombocytopenic Purpura
Amgen

Completed

Study to Evaluate the Efficacy and Safety of AMG 714 in Adult Patients With Type II Refractory Celiac Disease

Type II Refractory Celiac Disease (RCD-II) | In-situ Small Bowel T-cell Lymphoma

Spain, United States, Finland, France, Netherlands
Amgen

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AMG 282 in Healthy Subjects and Subjects With Chronic Rhinosinusitis With Nasal Polyps

Chronic Rhinosinusitis With Nasal Polyps

United States
Amgen

Terminated

Study to Evaluate the Safety, Tolerability, and Action of AMG 357 in Females With Rheumatoid Arthritis

Rheumatoid Arthritis

United States

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